Claim Missing Document
Check
Articles

Found 33 Documents
Search

EFEKTIFITAS PEMBERIAN JUS TOMAT TERHADAP LINGKAR PERUT DAN LEMAK TUBUH PADA TENAGA KESEHATAN DENGAN OBESITAS Florentinus Nurtitus; Agung Susanto; Tonang Ardyanto
GIZI INDONESIA Vol 45, No 2 (2022): September 2022
Publisher : PERSATUAN AHLI GIZI INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36457/gizindo.v45i2.703

Abstract

Obesity is an excess weight that is characterized by the Body Mass Index (BMI) 27kg/m2. Obesity in health professionals can potentially endanger health professionals. Tomatoes are a source of lycopene which has a protective effect against obesity. This study aims to analyze the effect of giving tomato juice on the waist circumference and body fat of health officers with obesity. This experimental study employed the pre-test and post-test control group design. The research sample comprised 66 individuals, divided into 2 groups. The Control group was given education on a low-calorie diet while the treatment group was given education on a low-calorie diet and 500 ml of tomato juice. The data analysis was conducted using paired–t-tests. After 30 days of treatment, there was a decrease in body fat levels in the treatment group by 1.32+1.4 (p=0.000). Meanwhile, in the control group, there was no significant difference (p=0.543). The treatment group experienced a decrease in waist circumference by 5+0.44 (p=0.000) and the control group had a difference of 3.12+2.61 (p=0.000). Tomato juice is effective in reducing waist circumference and body fat in obesity. It is necessary to consider the use of tomato juice in programs aimed at reducing waist circumference and body fat.
Blood Gas Analysis as A Predictor of Mortality in Critical COVID-19 Patients in Dr. Moewardi Hospital Surakarta Maria Sekar Cahyaningrum; Dian Ariningrum; Widana Primaningtyas; Tonang Dwi Ardyanto
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 29 No. 2 (2023)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v29i2.1970

Abstract

COVID-19 has been declared a global pandemic affecting many countries, including Indonesia. The worsening of COVID-19 patients may go unnoticed because one of the clinical manifestations of COVID-19 is silent hypoxia, where the patients’ blood oxygen saturation drops with no visible symptoms. Blood gas analysis is needed to detect silent hypoxia. This study aims to confirm whether blood gas analysis results correlate with the mortality of critical COVID-19 patients. This was a retrospective cohort study, the samples were taken from the medical records of critical COVID-19 patients from May 2020-July 2021. The variables observed were gender, age, comorbidities, oxygen saturation (SaO2), partial pressure of oxygen (PaO2), partial pressure of carbon dioxide (PaCO2), bicarbonate (HCO3-), and blood pH. Descriptive statistics, bivariate, and multivariate analyses were done. There were 210 samples, where 137 patients survived (65.24%) and 73 patients died (34.76%). The data analysis showed that comorbidities and blood pH significantly correlate with the mortality of critical COVID-19 patients, with p-values < 0.05; indicating that comorbidities and blood pH can be used as mortality predictors in critical COVID-19 patients. The RR for comorbidities and blood pH were 2.194 and 2>294, respectively, with CI 95% 1.202-4.833 for comorbidities and 1.151-5.295 for blood pH. The cut-off value used for blood pH was 7.310.
Neuthropil-to-Lymphocyte Ratio Correlation with Pneumonia Severity Index in COVID-19 Patients Hendrastutik Apriningsih; Nurhasan Agung Prabowo; Reviono; Betty Suryawati; Tonang Dwi Ardyanto
Nusantara Science and Technology Proceedings Multi-Conference Proceeding Series D
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2023.3004

Abstract

COVID-19 is still a major problem and characterized by the development and progression of inflammatory responses. Assessment of disease degree includes several tools, such as the pneumonia severity index (PSI). However, because the pandemic occurs in all regions in Indonesia, not all health facilities have a complete diagnostic tool to assess the severity of pneumonia. It is necessary to have an easy, inexpensive, and readily available examination to determine the COVID-19 disease's severity, such as Neutrophil-to-Lymphocyte Ratio (NLR). The purpose of this study was to determine the correlation between NLR and PSI in COVID-19 patients. The research was carried out on the COVID-19 ward of Universitas Sebelas Maret (UNS) Hospital in February 2021. Examination of laboratory parameters and X-rays was carried out when the patients entered the Emergency Room at the hospital. A prospective cohort study, with the population being patients >18 years old with mild to critical COVID-19 and being admitted from February to March 2021. Statistical analysis was conducted using the Pearson correlation test with SPSS 25, in which case p was deemed significant if it was <0.05. Results were obtained from 49 COVID-19 patients treated in the COVID-19 ward, whose mean age was 49.83 + 13.31, NLR and PSI were 8.85 + 13.25, 61.673 + 26.635, respectively. There was a strong positive correlation between NLR and PSI (p = 0.001; r = 0.488). NLR was correlated with PSI in COVID-19 patients.
THE RELATIONSHIP BETWEEN EMOTIONAL EATING, MEAL SKIPPING AND UNHEALTHY FOOD CONSUMPTION PATTERN IN ADOLESCENT GIRLS Nisri Ina Zahrah; Moh Fanani; Tonang Dwi Ardyanto
The Indonesian Journal of Public Health Vol. 18 No. 1 (2023): THE INDONESIAN JOURNAL OF PUBLIC HEALTH
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijph.v18i1.2023.47-58

Abstract

Introduction: Psychological problems can lead to emotional eating and meal skipping, which may impact unhealthy food consumption patterns. This study aimed to assess the interrelationship between emotional eating, meal skipping, and unhealthy food consumption pattern in adolescent girls. Method: This cross-sectional study included 122 samples of adolescent girls aged 13-15 years. The study was carried out in Tangerang, in June 2021. The data of emotional eating were measured by Emotional Eater Questionnaire (EEQ), meal skipping collected by self-reported questionnaire of daily eating frequency, and unhealthy food consumption patterns measured by Food Frequency Questionnaires (FFQ). Result: The results showed majority of emotional eater subjects more often consumed fatty foods (76.6%). It’s also found that adolescents  skipping breakfast were high in consumed sweet  foods (66.0%), while those skipping lunch (63.6%) and dinner (54.5%) were found higher to consume  fatty foods than others. In addition, multivariate regression analyses showed that simultaneously between the variables, only emotional eating variables had a significant  relationship with unhealthy food consumption patterns (p-value = 0.002), while meal skipping variables were not significantly related. Conclusion: It can be concluded that emotional eating can affect unhealthy food consumption patterns among adolescent girls, while meal skipping did not show  any meaningful effect.
Investigation of antioxidant activity from beetroot juice (Beta vulgaris L) as a healthy drink for the prevention of non-communicable disease Ratih Tri Amelia; Tonang Dwi Ardyanto; Yulia Sari
AcTion: Aceh Nutrition Journal Vol 9, No 1 (2024): March
Publisher : Department of Nutrition at the Health Polytechnic of Aceh, Ministry of Health

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/action.v9i1.1444

Abstract

Non-communicable diseases can cause oxidative stress, which affects their pathophysiology. One of the recommended diets for preventing complications of non-communicable diseases (NCD) is a rich antioxidant diet. One of the foods rich in antioxidants is beetroots. This study aimed to assess the antioxidant content of locally obtained beetroot juice. Laboratory experimental methods were used to test the antioxidant activity of beetroot juice. Before the laboratory test, the panelists carried out a hedonic test. The beets were then juiced and checked for DPPH′ (2,2-diphenyl-1-picrylhydrazyl). The beetroot was then juiced and checked for DPPH′ (2,2-diphenyl-1-picrylhydrazyl). Statistical analysis was performed using the Kruskal–Wallis test.  Results: The hedonic test showed that panelists preferred beetroot juice with lemon juice, with a 'like' range for the aroma and viscosity and a 'neutral-like' range for the taste and color of beetroot juice. The antioxidant content in 300 ml of beetroot juice was 53,34 ± 0,13%. In conclusion, beetroot juice has a high antioxidant content and health benefits in preventing NCD.
Perception of Body Image Related to Nutritional Status of Young Women in Pontianak City During the Covid-19 Pandemic Deviro Deviro; Tonang Dwi Ardyanto; Anik Lestari
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 8, No 2: June 2023
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (623.761 KB) | DOI: 10.30604/jika.v8i2.1744

Abstract

Covid 19 is a pandemic disease experienced throughout the world. This pandemic causes limitations on activities outside the home so it will impact the health and mentality of adolescents. Adolescent girls are in a period of transition from children to adults. Adolescence is an age that is very vulnerable to nutritional problems, this is caused by a lack of self-confidence, lifestyle, and knowledge of balanced nutrition. Often, young women feel dissatisfied with their body shape, so they go on a diet to get the desired body shape. This study aimed to determine the relationship between body image and nutritional status in young women during the Covid 19 pandemic in Pontianak City. This research is an observational study with a cross-sectional design chosen randomly and then the Pontianak Health Polytechnic, Stikes Yarsi, and Aisyiyah Polytechnic were selected. The sample in the study was 102 female students using sampling using proportional random sampling. Data collection was carried out in March-April 2022. The data collection technique measured the waist-hip ratio (RLPP) and used a figure rating scale questionnaire with a Cronbach alpha of 0.85. Then the data were analyzed using the chi-square test with a 95% confidence level. The results of this study indicate that 76 respondents (74.5%) have a negative body image and 26 respondents (25.5%) have a positive body image. In comparison, regarding the nutritional status of young women 74 respondents (72.5%) were obese and 28 respondents (27.5%) were not obese. The chi-square test results were obtained with p = 0.00 (p less than 0.05). This shows a relationship between body image and the nutritional status of young women in Pontianak City during the Covid 19 pandemic. Young women who experience nutritional status obesity tend to have a negative body image compared to young women whose nutritional status is not obese tend to have a positive body image. Abstrak: Covid 19 merupakan penyakit pandemi yang dialami seluruh dunia. Pandemi ini menyebabkan keterbatasan kegiatan diluar dirumah sehingga akan berdampak kesehatan dan mental pada remaja. Remaja putri merupakan masa peralihan dari anak-anak ke dewasa. Usia remaja merupakan usia yang sangat rentan terhadap permasalahan gizi hal tersebut diakibatkan oleh kurang kepercayaan diri, gaya hidup serta kurangnya pengetahuan gizi seimbang. Seringkali remaja putri memiliki rasa ketidakpuasaan terhadap bentuk tubuhnya sehingga remaja akan melakukan diet untuk mendapatkan bentuk tubuh yang diinginkan. Tujuan Penelitian ini adalah untuk mengetahui hubungan body image dengan status gizi pada remaja putri selama masa pandemi covid 19 di Kota Pontianak. Penelitian ini merupakan penelitian observasional dengan desain cross sectional yang dipilih secara random kemudian terpilih politeknik kesehatan Pontianak, stikes yarsi dan politeknik aisyiyah. sampel pada penelitian sebanyak 102 mahasiswa putri dengan cara pengambilan sampelnya menggunakan proportional random sampling. Pengambilan data dilakukan di bulan maret-april 2022. Teknik pengumpulan data menggunakan perngukuran rasio lingkar pinggang-panggul (RLPP) dan menggunakan kuesioner figure rating scale dengan alpha cronbach sebesar 0,85. Kemudian data dianalisis menggunakan uji chi-square dengan tingkat kepercayaan 95%. Hasil dari penelitian ini menunjukkan bahwa sebanyaj 76 responden ( 74,5%) mempunyai body image negatif dan 26 responden (25,5%) memiliki body image positif, sedangkan status gizi pada remaja putri sebanyak 74 responden (72,5%) obesitas dan 28 responden (27,5%) tidak obesitas. Hasil dari uji chi-square diperoleh dengan nilai p=0,00 (p kurang dari 0,05). Hal tersebut menunjukkan bahwa ada hubungan body image dengan status gizi remaja putri di Kota Pontianak selama masa pandemi covid 19. Remaja putri yang mengalami status gizi obesitas cenderung memiliki body image negatif dibandingkan remaja putri yang status gizinya tidak obesitas cenderung memiliki body image positif.
Post COVID-19 vaccination binding and neutralizing antibody with or without previous infection: An 18-month longitudinal study in Indonesia Ardyanto, Tonang D.; Khariri, Khariri; Agus, Telly P.; Subandrio, Amin
Narra J Vol. 4 No. 2 (2024): August 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v4i2.1071

Abstract

Due to the persisting development of SARS-CoV-2 variants, studies on the kinetics, duration, and function of antibodies are essential for vaccine development and long-term immunity prediction. This longitudinal study examined post-vaccination antibody responses in people after receiving CoronaVac or ChAdOx1 vaccines with or without a history of SARS-CoV-2 infection. Conducted in Indonesia between August 2021 and May 2023, this study involved 121 participants divided into two groups based on the received vaccine types and monitored for 18 months post-second dose vaccination by assessing the binding antibody (BAb) level and neutralizing antibody (NAb) inhibition rate at six time points. The study also documented the participants’ age, gender, and body mass index (BMI). Before the first dose vaccination, 85 (70.25%) participants were reactive BAb (defined by BAb level ≥50 AU/mL) indicating a history of infection. In the CoronaVac group, only 53.1% were reactive BAb. However, 100% of participants were positive NAb (defined by NAb inhibition rate ≥30%), which indicates a past history of infection with low initial or rapidly decreasing BAb levels. In the ChAdOx1 group, 81,9% of participants were reactive, while only 54.2% were positive NAb, suggesting a recent infection with a high BAb level but a relatively low NAb inhibition rate. During the 18 months post-second dose vaccination, the BAb levels fluctuated. However, 100% of participants were positive NAb. No significant difference in antibody response was documented among participants with or without infection history. Also, no significant impact was presented by the factors of sex, age, and BMI. The findings highlight the crucial of the vaccine in public health and how vaccination strategies could be optimized effectively during and after the post-pandemic.
TINGKAT EFEKTIVITAS DETEKSI MANDIRI HIPERTENSI OLEH KOMUNITAS DI PUSKESMAS GAJAHAN Myrtha, Risalina; Ardyanto, Tonang Dwi; Prabowo, Nurhasan Agung; Apriningsih , Hendrastutik; Dyanneza, Frieska; Kuncorowati, Niken Dyah Aryani; Nugroho, Novianto Adi; Suwandono, Adji; Sari, Maria Galuh Kamenyangan; Shofiyah, Laily
Sebatik Vol. 28 No. 1 (2024): June 2024
Publisher : STMIK Widya Cipta Dharma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46984/sebatik.v28i1.2323

Abstract

Pengabdian ini bertujuan untuk menguatkan peran komunitas dalam kemandirian kesehatan melalui deteksi mandiri hipertensi dan kelainan irama jantung di Puskesmas Gajahan. Peningkatan prevalensi penyakit tidak menular, khususnya hipertensi dan fibrilasi atrium, memerlukan intervensi berbasis komunitas yang efektif untuk mengurangi beban penyakit ini. Metode pengabdian ini melibatkan pada kader kesehatan di wilayah kerja Puskesmas Gajahan dengan melakukan edukasi dan pelatihan kepada kader puskesmas Gajahan mengenai cara deteksi mandiri hipertensi dan kelainan irama jantung. Pelatihan ini mencakup cara pengukuran tekanan darah mandiri dan cara deteksi mandiri kelainan irama jantung dengan cara meraba nadi sendiri (MENARI), serta edukasi mengenai faktor risiko dan tanda-tanda kedua penyakit ini. Hasil dari implementasi pelatihan ini menunjukkan peningkatan pengetahuan dan keterampilan masyarakat dalam mendeteksi dini hipertensi dan kelainan irama jantung. Partisipan yang mengikuti pelatihan mampu melakukan pemeriksaan tekanan darah dan deteksi kelainan irama jantung secara mandiri dengan benar. Selain itu, terdapat peningkatan kesadaran masyarakat tentang pentingnya pemeriksaan kesehatan rutin dan perubahan gaya hidup untuk mengurangi risiko penyakit tidak menular. Kesimpulannya, penguatan peran komunitas melalui edukasi dan pelatihan deteksi mandiri terbukti efektif dalam meningkatkan kemandirian kesehatan masyarakat di wilayah kerja Puskesmas Gajahan.
Neuthropil-to-Lymphocyte Ratio Correlation with Pneumonia Severity Index in COVID-19 Patients Hendrastutik Apriningsih; Nurhasan Agung Prabowo; Reviono; Betty Suryawati; Tonang Dwi Ardyanto
Nusantara Science and Technology Proceedings Multi-Conference Proceeding Series D
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2023.3004

Abstract

COVID-19 is still a major problem and characterized by the development and progression of inflammatory responses. Assessment of disease degree includes several tools, such as the pneumonia severity index (PSI). However, because the pandemic occurs in all regions in Indonesia, not all health facilities have a complete diagnostic tool to assess the severity of pneumonia. It is necessary to have an easy, inexpensive, and readily available examination to determine the COVID-19 disease's severity, such as Neutrophil-to-Lymphocyte Ratio (NLR). The purpose of this study was to determine the correlation between NLR and PSI in COVID-19 patients. The research was carried out on the COVID-19 ward of Universitas Sebelas Maret (UNS) Hospital in February 2021. Examination of laboratory parameters and X-rays was carried out when the patients entered the Emergency Room at the hospital. A prospective cohort study, with the population being patients >18 years old with mild to critical COVID-19 and being admitted from February to March 2021. Statistical analysis was conducted using the Pearson correlation test with SPSS 25, in which case p was deemed significant if it was <0.05. Results were obtained from 49 COVID-19 patients treated in the COVID-19 ward, whose mean age was 49.83 + 13.31, NLR and PSI were 8.85 + 13.25, 61.673 + 26.635, respectively. There was a strong positive correlation between NLR and PSI (p = 0.001; r = 0.488). NLR was correlated with PSI in COVID-19 patients.
Challenges in diagnosing and treating Liddle syndrome in resource-limited settings: A case report from Indonesia Prabowo, Nurhasan A.; Putranto, Wachid; Myrtha, Risalina; Ardyanto, Tonang D.; Gautama, Coana S.; Wulandari, Evi L.; Hermawati, Berty D.; Putri, Desy P.; Ramadhani, Artika; Dewi, Herlina K.
Narra J Vol. 4 No. 3 (2024): December 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v4i3.1000

Abstract

Liddle syndrome, a rare form of monogenic hypertension, poses significant diagnostic and therapeutic challenges due to its phenotypic variability and the need for genetic testing. The rarity of the condition, coupled with the limited availability of first-line treatments such as epithelial sodium channel (ENaC) blockers, makes this case report particularly urgent and novel, highlighting alternative management strategies in resource-limited settings. The aim of this case report was to present the diagnostic challenges, therapeutic strategies, and clinical outcomes of a patient with Liddle syndrome who did not have access to ENaC blockers, emphasizing the importance of early recognition and personalized treatment. A 35-year-old female presented with resistant hypertension (190/100 mmHg) and bilateral limb weakness. Laboratory results revealed persistent hypokalemia, hypernatremia, and metabolic alkalosis. Low aldosterone levels, alongside clinical and family history, led to the diagnosis of Liddle syndrome. Genetic testing was not conducted due to resource limitations, and ENaC blockers were unavailable. The patients were managed with a combination of alternative antihypertensive agents, potassium supplementation, and a low-sodium diet. Although this approach led to modest improvements in blood pressure and motor strength, persistent hypokalemia and hypernatremia underscored the suboptimal control of the syndrome's underlying pathophysiology in the absence of ENaC blockers. This case highlights the challenges faced in resource-limited settings and the need for innovative strategies to manage rare conditions like Liddle syndrome. Liddle syndrome's diagnostic and therapeutic challenges underscore the critical importance of early recognition and access to targeted therapies. In the absence of ENaC blockers, alternative treatment strategies can provide some benefit, but they often fall short of optimal management. This case emphasizes the need for enhanced clinical awareness, improved access to genetic testing, and the development of personalized treatment approaches to achieve better patient outcomes.
Co-Authors Adang Muhammad Gugun, Adang Muhammad Adji Suwandono adji suwandono Agung Susanto Agus Kristiyanto Agus Kristiyanto Agus Sholikin Agus Sholikin Agus, Telly P. Ambar Mudigdo Amilia Yuni Damayanti Amin Subandrio, Amin Andikashwari, Sekarnira Andri Haryanto Anik Lestari Anwar, Fuad Aprilningsih, Hendrastutik Apriningsih, Apriningsih Apriningsih Apriningsih, Hendrastutik Ari Natalia Probandari Ari Probandari Ariningrum, Dian Artika Ramadhani Astri Tantri Indriani Astri Tantri Indriani Astri Tantri Indriani Avelia, Annisa Ayunda Oktavia Badri, Baarizah Febriana Benyamin Saut Berty Denny Hermawati Betty Suryawati Bismantara, Haryo Brian Wasita Brian Wasita Cari Cari Citra Jaya Dedy Revelino Delta Nur Septianingsih Deviro Deviro Dewi, Herlina K. Donald Pardede Dono Indarto Dyanneza, Frieska Dyanneza, Frieska Elfi Susanti V. H. Ema Nur Fitriana Endang Suparniati Erzan Dhanalvin Eti Poncorini Pamungkasari Fajar Rakhman Wibowo Firdaus Hafidz As Shidieq Firdaus, Nais Volum Florentinus Nurtitus Gautama, Coana S. Gilbert Renardi Kusila Hendrastutik Apriningsih Hendrastutik Apriningsih Hendrastutik Apriningsih Hendrastutik Apriningsih Hendrastutik Apriningsih Hendrastutik Apriningsih Hermawati, Berty D. Hidayat, Syamsu Ida Nurwati Ika Mukti Virgiyanti Ika Mukti Virgiyanti Indriani, Astri Tantri Iskandar, Kasir Isnanda Putri Nur Istiqomah Istiqomah, Isnanda Putri Nur Khariri Khariri Kuncorowati, Niken Dwi Aryani Kuncorowati, Niken Dyah Aryani Kurniawati, Golda Laily Shofiyah Laily Shofiyah Lestari, Nova Dwi Maria Galuh Kamenyangan Maria Galuh Kamenyangan Sari Maria Galuh Kamenyangan Sari Maria Galuh Kamenyangan Sari, Maria Galuh Kamenyangan Maria Sekar Cahyaningrum Moh Fanani Mohtar Yunianto Muchtar Hanafi Muttaqien Muttaqien, Muttaqien Myrtha, Risalina Niken Dwi Aryani Kuncorowati Niken Dyah Aryani Kuncorowati Niken Dyah Aryani Kuncorowati Niken Dyah Aryani Kuncorowati Niken Dyah Aryani Kuncorowati Nisri Ina Zahrah Novianto Adi Nugroho Novianto Adi Nugroho Novianto Adi Nugroho Nugroho, Novianto Adi Nur Hafidha Hikmayani Nurhasan Agung Prabowo Prabowo, Nurhasan A. Putranto, Wachid Putri, Desy P. Qadrijati, Isna Ragil Rahma Nafila Ratih Tri Amelia Resta Farits Pradana Reviono Rini Astuti Risalina Myrtha Risalina Myrtha Risalina Myrtha Risalina Myrtha Rizky Amalia Puspitaningrum Rusliana, Eka Samodra, Imam Shofiyah Shofiyah, Laily Soeparmi Soeparmi Soetrisno Soetrisno Sri Indratni Sri Indratni Sri Mulyani Sugiarto Sugiarto Tahono Tahono Tsalatshita, Risky Wan Aisyiah Baros Widana Primaningtyas Wulandari, Evi L. Yeni Farida Yulia Sari Yulita Hendrartini