Aryati Aryati
Dengue Study Group, Institute Of Tropical Disease, Universitas Airlangga, Mulyorejo Street, Mulyorejo 60115, Surabaya, East Java, Indonesia Clinical Pathology Department, Faculty Of Medicine, Universitas Airlangga, Prof.Dr.Moestopo Street, Tambaksari

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Journal : indonesian journal of medical laboratory science and technology

Validation of Rapid Antibody (IgM – IgG) Test Kit for SARS-CoV-2 Infection in Surabaya, Indonesia Museyaroh, Museyaroh; Wardani, Puspa; Aryati, Aryati; Woelansari, Evy Diah
JURNAL INDONESIA DARI ILMU LABORATORIUM MEDIS DAN TEKNOLOGI Vol 4 No 2 (2022): Enhanced knowledge of laboratory medicine's role in healthcare
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/ijmlst.v4i2.3027

Abstract

At the beginning of the Corona Virus Disease 2019 (COVID-19) pandemic, rapid test examinations were widely used as a screening for Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection. The purpose of this examination was to detect SARS-CoV-2 IgM/IgG antibodies in the patient's body. One of these tests uses the immunochromatographic method. This study aims to determine the validity of immunochromatography. The study was conducted from August to September 2020. The sample used in this study was 100 patients. The research was conducted at Husada Utama Hospital Surabaya, Indonesia. According to the study's findings, the Zybio brand reagent kit has an accuracy of 85%, a sensitivity of 82%, a specificity of 88%, a positive predictive value of 87%, and a negative predictive value of 83%. In the group of patients who experienced clinical symptoms, < 7 had a sensitivity of 50%, specificity of 88%, positive predictive value of 60%, negative predictive value of 83%, and accuracy of 77.94% while the group of patients experiencing clinical symptoms > 7 days, had a sensitivity value of 100 %, specificity of 88%, positive predictive value of 84%, negative predictive value of 100%, and accuracy of 92.68%. Based on these results, the conclusion is that the Zybio brand reagent kit has a relatively high sensitivity, specificity, positive predictive value, negative value, and sample accuracy. In the group with clinical sensitivity < 7 days, the positive predictive value and accuracy are lower than the sample group with clinical symptoms > 7 days but have the same specificity.
Co-Authors Agus Santosa Agus Sulistyono Agustin Iskandar Aksono HP., Eduardus Bimo Alida Roswita Harahap Anak Agung Wiradewi Lestari Andrea Aprilia Andyanita Hanif Hermawati Anniwati, Leonita AR, M. Yazid Ariani, Grace Arifoel Hajat Bastiana Bastiana Budi Utomo Budiailmiawan, Luhung Cavalier, Etienne Darto Saharso Desak Gde Ushadi Bulan Dewata Dewi Wulandari Djoko Santoso Doddy M. Soebadi Dominicus Husada Dwiyanti Puspitasari, Dwiyanti Eko Sulistijono Erawati Erawati Erni Juwita Nelwan, Erni Juwita Erwin Astha Triyono Evy Diah Woelansari Fahimah Martak Ferdy Royland Marpaung Gondo Mastutik Handayani, Cut Fitri Harianto Notopuro Harsasi Setyawati Haryanto, Isnaeni Yudi Hebert Adrianto Heny Arwati Herdiman Theodorus Pohan Hermina Novida, Hermina I A Putri Wirawati I Dewa Gede Ugrasena Ilham Harlan Amarullah Indah Susanti Iris Rengganis Isnaeni Isnaeni Yudi Haryanto Isnin Anang Marhana Jusak Nugraha Kris Cahyo Mulyatno, Kris Cahyo Kuntaman Kuntaman Kusmiati, Tutik Kusumastuti, Etty H. Laksita, Tetuka B. Lulut Kusumawati Lumban Toruan, Anggia Augustasia M. Andriady S. Nasution Maharani, Anisa Mardiyah, Nikmatul Margalin, Brilliant Marpaung, Ferdy Royland Masanori Kameoka, Masanori Ma`ruf, Anwar Merylin Ranoko Mohammad Guritno Suryokusumo Mufasirin Muhammad Nazarudin Muhammad Rivai Museyaroh, Museyaroh Mustika Amri Nabil Salim Ambar Nia Saurina Niluh Suwasanti Norwahyuni, Yuyun Nunki, Nastasya Nur Chamidah Nurdianto, Arif Rahman Partakususma, Lia Gardenia Patria Dewi, Pande Putu Ayu Perbowo, Primandono Pranidya, Nada Putri Purnomo, Windu Puspa Wardhani R Raharjo, Paulus R. Tedjo Sasmono Rahmawati, Lita Diah Retno Palupi Riries Rulaningtyas Rizaliansyah, Ferdian Rizqidhana Juliana Putri Rohmayana, Sri Rony, Zahara Tussoleha Royland Marpaung, Ferdy Rusli, Musofa Saptawati Bardosono Saraswati Dewi Sari, Arabella Vonia Sari, Sri Kartika Sasmono, R. Tedjo Serlin serang Setianingsih, Yennie A. Shifa Fauziyah Shuhai Ueda Siti Churrotin, Siti Soegeng Soegijanto Sofro, Muchlis AU Sri Masyeni, Dewa Ayu Putri Sri Subekti Sri Sumarsih Suci Andriani Suhendro Suhendro SUKACITA TEHUPURING Sunari, I Gusti Agung Ayu Eka Putri Sunaryo Hardjowijoto Syamsu Nujum Teguh Hari Sucipto, Teguh Hari Theresia Indah Budhy Sulisetyawati Thomas Tandi Manu Tjokroprawiro, Brahmana A. Tomohiro Kotaki, Tomohiro Trieva Verawaty Butarbutar Ueda, Shuhai Usman Hadi wahjoe djatisoesanto Wardani, Puspa Wardhani, Puspa Wibrianto, Aswandi Widajati, Rahma Widodo J Pujiraharjo Yetti Hernaningsih Yohan, Benediktus Yovilianda Maulitiva Untoro Yulia Iriani, Yulia Yulia Nadar Indrasari Yuliasih Yusuf, Laily Indrayanti