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All Journal Journal of Agromedicine and Medical Sciences Sosio Konsepsia Dentino: Jurnal Kedokteran Gigi Berkala Kedokteran Sari Pediatri Jurnal Sinergitas PkM & CSR MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan YARSI Medical Journal Tropical Wetland Journal Dentin Bioinformatics and Biomedical Research Journal Prosiding Konferensi Nasional PKM-CSR JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Homeostasis: Jurnal Mahasiswa Pendidikan Dokter DUNIA KEPERAWATAN: JURNAL KEPERAWATAN DAN KESEHATAN JOURNAL OF WETLANDS ENVIRONMENTAL MANAGEMENT
Lia Yulia Budiarti
Faculty Of Medicine University Of Lambung Mangkurat, Banjarmasin, South Kalimantan, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Control & Systems Engineering Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Pola Resistensi Bakteri Kontaminan Luka Pasien di Bangsal Bedah Ortopedi RSUD Ulin Banjarmasin Periode Juli-September 2013: Tinjauan In Vitro Pola Resistensi Isolat Bakteri Kontaminan Asal Swab Luka Pasien di Bangsal Bedah Ortopedi RSUD Ulin Banjarmasin Terhadap Gentamisin, Kloramfenikol, Sefotaksim dan Seftriakson Rihansyah, Akbar; Putera, Husna Dharma; Budiarti, Lia Yulia
Berkala Kedokteran Vol 10, No 2 (2014): September 2014
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v10i12.964

Abstract

ABSTRACT: Surgery, trauma, burns, and other factors can affect the defense/skin barrier against bacterial contamination that can cause infection. The risk of infection must be remained of the rational use of prophylactic antibiotics. Rational use of antibiotic susceptibility test results obtained by antibotic against bacteria. The aim of this research was to figure out the resistance pattern of bacteria contaminant in patient’s wound at Orthopaedic Ward of RSUD Ulin Banjarmasin to selected antibiotics i.e. gentamicin, chloramphenicol, cefotaxime and ceftriaxone from July-September 2013. This was descriptive research. The samples were taken with consecutive sampling technique according to inclusion criteria. This research used wound swab bacteria contaminant isolates i.e. Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, and Streptococcus sp. Antibiotic susceptibility test was done in vitro with Kirby-Bauer diffusion method. The radical zones were measured and compared to CLSI 2011 standard. The antibiotic susceptibility test result showed that Staphylococcus aureus was sensitive to gentamicin (100%) and cefotaxime (66,67%), resistant to chloramphenicol (44,44%); Staphylococcus epidermidis was sensitive to cefotaxime (28,75%), resistant to gentamicin (85,71%) and chloramphenicol (57,14%); Pseudomonas aeruginosa was sensitive to cefotaxime (33,33%), resistant to ceftriaxone (66,67%); Streptococcus sp. was sensitive to cefotaxime (50%), resistant to gentamicin (50%), chloramphenicol (100%) and ceftriaxone (50%). Key words:   Antibiotic susceptibility, wound bacterial contaminant. ABSTRAK: Tindakan operasi, trauma, luka bakar dan beberapa faktor lain dapat mempengaruhi pertahanan/barier kulit terhadap kontaminasi bakteri yang dapat menyebabkan infeksi. Risiko terjadinya infeksi harus tetap diwaspadai dengan penggunaan antibiotik profilaksis yang rasional. Penggunaan antibiotik rasional didapatkan berdasarkan hasil uji kepekaan antibotik terhadap bakteri penyebab. Penelitian ini bertujuan untuk mengetahui pola resistensi bakteri kontaminan pada luka pasien di Bangsal Bedah Ortopedi RSUD Ulin Banjarmasin terhadap beberapa antibiotik yaitu gentamisin, kloramfenikol, sefotaksim dan seftriakson periode Juli-September 2013. Penelitian ini bersifat deskriptif. Pengambilan sampel menggunakan teknik consecutive sampling menurut kriteria inklusi. Penelitian ini menggunakan isolat bakteri kontaminan hasil swab luka pasien yaitu Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, dan Streptococcus sp. Uji kepekaan keempat jenis bakteri tersebut dilakukan secara in vitro dengan metode difusi Kirby-Bauer. Zona radikal yang terbentuk diukur dan dibandingkan dengan standar CLSI 2011. Hasil uji kepekaan antibiotika menunjukkan bahwa Staphylococcus aureus sensitif terhadap gentamisin (100%) dan sefotaksim (66,67%), resisten terhadap kloramfenikol (44,44%); Staphylococcus epidermidis sensitif terhadap sefotaksim (28,75%), resisten terhadap gentamisin (85,71%) dan kloramfenikol (57,14%); Pseudomonas aeruginosa sensitif terhadap sefotaksim (33,33%), resisten terhadap seftriakson (66,67%); Streptococcus sp. sensitif terhadap sefotaksim (50%), resisten terhadap gentamisin (50%), kloramfenikol (100%) dan seftriakson (50%). Kata-kata kunci : Kepekaan antibiotika, bakteri kontaminan luka.
Identifikasi Bakteri Penyebab Infeksi Saluran Kemih pada Pasien Urolithiasis di Ruang Perawatan Bedah RSUD Ulin Banjarmasin Periode Juni-Agustus 2013 Nufaliana, Sri Hayati; Rahman, Eka Yudha; Budiarti, Lia Yulia
Berkala Kedokteran Vol 10, No 2 (2014): September 2014
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v10i12.960

Abstract

ABSTRACT: Urinary tract stone or urolithiasis is a pathological condition which is presented by the existence of the stone in the urinary tract. The existence of this stone may make the normal imunity of urinary tract decrease, so that the bacteria can enter, stay and grow until make urinary tract infection (UTI). Urinary tract infection is diagnosed by finding cases of positive urine culture (>105cfu/ml). The aim of this research was to figure out the type of bacteria in urolithiasis patients with UTI at surgical treatment room of RSUD Ulin Banjarmasin during June-August 2013. This study was a descriptive research with cross sectional approach. The samples were taken with totally sampling methode who fullfilled  inclusion criteria. There were 19 urolithiasis patients at surgical treatment room of RSUD Ulin Banjarmasin. From urine examination, there were 13 patients with UTI. Bacterial identification showed there were 3 types of bacteria, Escherechia coli (53,84%), Pseudomonas aeruginosa (38,46%), and Proteus sp. (7,69%). Keywords: urinary tract infection, urinary tract infection’s bacteria, urolithiasis ABSTRAK: Batu saluran kemih atau urolithiasis adalah suatu kondisi patologis yang ditandai dengan keberadaan batu di sepanjang traktus urinarius. Kehadiran batu ini dapat membuat pertahanan saluran kemih yang normal berkurang, sehingga bakteri dapat masuk, menetap dan berkembang biak yang akhirnya menimbulkan infeksi saluran kemih (ISK). ISK dapat didiagnosis jika ditemukan koloni bakteri (>105cfu/ml). Penelitian ini bertujuan untuk mengetahui gambaran jenis bakteri penyebab ISK pada pasien urolithiasis di ruang perawatan bedah RSUD Ulin Banjarmasin selama periode Juni-Agustus 2013. Penelitian ini bersifat deskriptif dengan pendekatan cross sectional. Pengambilan sampel menggunakan totally sampling method menurut kriteria inklusi. Sampel pada penelitian ini adalah 19 pasien urolithiasis di ruang perawatan bedah RSUD Ulin Banjarmasin. Hasil pemeriksaan urine dari 19 pasien urolithiasis diperoleh 13 pasien urolithiasis dengan ISK. Hasil identifikasi bakteri pada 13 pasien urolithiasis dengan ISK didapatkan bakteri penyebab ISK pada pasien urolithiasis yaitu Escherechia coli (53,84%), Pseudomonas aeruginosa (38,46%), dan Proteus sp. (7,69%). Kata-kata kunci: bakteri penyebab ISK, infeksi saluran kemih, urolithiasis
JENIS BAKTERI DAN JAMUR KONTAMINAN UDARA DI RUANG PERAWATAN SUB BAGIAN PENYAKIT DALAM RUMAH SAKIT UMUM DAERAH BANJARBARU Yulia Budiarti, Lia; Noormuthmainah, Noormuthmainah; Rahmiati, Rahmiati
Jurnal Kedokteran YARSI Vol 15, No 1 (2007): JANUARI - APRIL 2007
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (184.807 KB) | DOI: 10.33476/jky.v15i1.1005

Abstract

Nosocomial infection is one of the major health problem in the world. One of the way for transmitting the causative microorganism of nosocomial infection is airborne. This research had been done to know kinds of air contaminating bacteria in sub departement of internal disease science of General Hospital Banjarbaru. This research was laboratory descriptive using ?open plate? method. The results of research described that there were five kinds of bacteria, they were Staphylococcus epidermidis 38,07%, Escherichia coli 27,52%, Streptococcus ? haemolyticus 19,26%, Pseudomonas aeruginosa 10,55% and Staphylococcus aureus 4,58% and five kinds of fungi: Rhizopus sp. (37,78%), Aspergillus niger (20%), Trichosporon sp. (17,78%), Penicilliumsp. (13,33%) and Aspergillus flavus (11,11%).
Phenol Coefficient Test Combination Infusion of Cananga odorata – Averrhoa bilimbi L. Against Staphylococcus aureus and Salmonella typhi in Vitro Budiarti, Lia Yulia; Wydiamala, Erida; Ulfa, Najiya
Bioinformatics and Biomedical Research Journal Vol. 4 No. 1 (2021): Vol 4 No 1 (2021)
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/bbrj.04.01.03

Abstract

Cananga odorata (kenanga) flowers and Averrhoa bilimbi L. (belimbing wuluh) fruit are plant parts that contain relatively the same antibacterial compounds, namely flavonoids, saponins, and tannins. Both of these plants can be developed as an alternative natural antiseptic preparation, which is made in the form of a combination infusion. The effectiveness of an antiseptic preparation is measured by the coefficient value of the phenol antiseptic substance compared to 5% phenol against several standard test bacteria. This study aims to determine the antibacterial activity of the combination infusion of Cananga odorata flower - Averrhoa bilimbi L. fruit against Staphylococcus aureus ATCC 25923 and Salmonella typhi ATCC 19430 based on the in vitro phenol coefficient test. The phenol coefficient test method was carried out conventionally. The coefficient value close to 1 can be said that the antiseptic preparation has good activity and is equivalent to the phenol coefficient value as a comparison. The results showed that the mean coefficient of the phenol coefficient of the combination infusion of Cananga odorata flower - Averrhoa bilimbi L. fruit was 0.91 against S. aureus and 0.83 against S. typhi. The conclusion of this study, the antibacterial activity of the combination infusion of Cananga odorata flower - Averrhoa bilimbi L. fruit against Staphylococcus aureus obtained a higher phenol coefficient value than Salmonella typhi.
Antimicrobial Activity of Stenochlaena palustris and Sauropus androgynus in Staphylococcus aureus, Escherichia coli and Candidia albicans Budiarti, Lia Yulia; Isnaini, Isnaini; Dayana, Puteri; Sari, Norma; S., Nur Almira R.
Bioinformatics and Biomedical Research Journal Vol. 4 No. 1 (2021): Vol 4 No 1 (2021)
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/bbrj.04.01.05

Abstract

Stenochlaena palustris and Sauropus androgynus are known to contains antimicrobial substances such as flavonoids, saponins and tannins compounds.The purpose of this study was to analyzes the antimicrobial activity of young and old leaf infusions of S. palustris and S. androgynus leaves against Staphylococcus aureus, Escherichia coli and Candida albicans. Analyze the antibacterial activity of a single preparations with a combination preparation of S.palustris (SP) and S.androgynus (SA) leaves infusion against S.aureus, E.coli and C.albicans. Leaves of S.palustris young part (SP1) taken 0-10 cm from shoots and old parts (SP2) 11-20 cm from shoots, while leaves of S.androgynus young part (SA1) leaves number 1 - 10 from the top and the old part (SA2) leaves number 11-20 from the top. The results showed that a single infusion of SP1 75% and SP2 75%, SA1 90% and SA2 90%, and a combination of SP1 75% and SA1 75%, SP2 75% and SA2 75% have the same activity as ampicillin in S.aureus. Single infusion of SP1 90% and SP2 90%, SA1 90% and SA2 90%, combination of SP1 75% and SA1 80% and the combination of SP2 80% and SA2 60% have the same activity as ciprofloxacin in E. coli. Single infusion of SP1 90% and SP2 90%, and a combination of SP1 80% and SA1 80%, SP2 80% and SA2 80% have the same activity as ketoconazole in C.albicans. The difference in activity due to differences in leaf parts used only occurred in E. coli, whereas in S.aureus and C.albicans (p <0.05).
ANALISIS KEYAKINAN DIRI DAN KESEJAHTERAAN PSIKOLOGIS PEDAGANG DI PASAR TRADISIONAL DARAT DAN PASAR TERAPUNG LOK BAINTAN SUNGAI TABUK MARTAPURA Lia Yulia Budiarti; Sukma Noor Akbar; Dwi Nur Rachmah
Sosio Konsepsia Vol 4 No 2 (2015): Sosio Konsepsia
Publisher : Puslitbangkesos Kementerian Sosial RI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33007/ska.v4i2.117

Abstract

AbstrakPenelitian ini bertujuan untuk mengetahui hubungan antara keyakinan diri dan kesejahteraan psikologispada pedagang di pasar tradisional darat dan pasar terapung. Selain itu penelitian ini juga ingin mengetahuiperbedaan keyakinan diri dan kesejahteraan psikologis pada pedagang pasar tradisonal darat dan pedagangpasar terapung. Metode penelitian pada penelitian ini adalah menggunakan metode kuantitatif. Analisisdata yang digunakan adalah analisis korelasi product moment Pearson’s dan analisis independent samplet-test. Subjek penelitian ini adalah 30 orang pedagang di pasar tradisional darat dan 30 orang pedagang dipasar terapung Lok Baintan Sungai Tabuk Martapura Kalimantan Selatan dengan menggunakan tekhnikpurposive sampling. Hasil penelitian menunjukkan bahwa ada hubungan antara keyakinan diri dankesejahteraan psikologis pada pedagang di pasar tradisional darat dan pedagang di pasar terapung, sertaterdapat perbedaan kesejahteraan psikologis pada pedagang di pasar tradisional darat dan pedagang di pasarterapung, tetapi tidak ada perbedaan keyakinan diri pada pedagang di pasar tradisional darat dan pedagangdi pasar terapung.Kata kunci: keyakinan diri, kesejahteraan psikologis, pedagang pasar tradisional darat, pedagang pasarterapung.
Pola Sensitivitas In Vitro Salmonella Typhi Terhadap Antibiotik Kloramfenikol, Amoksisilin, Dan Kotrimoksazol: Di Bagian Anak RSUD Ulin Banjarmasin Periode Mei-September 2012 Silvan Juwita; Edi Hartoyo; Lia Yulia Budiarti
Berkala Kedokteran Vol 9, No 1 (2013)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (236.585 KB) | DOI: 10.20527/jbk.v9i1.915

Abstract

ABSTRACT: Incidence of typhoid fever in children is still considered high, especially in the Paediatric Department of RSUD Ulin Banjarmasin, so the effective and efficient treatment was required. The sensitivity test of organisms which tends to be resistance like Salmonella typhi is very important because each region has different sensitivity pattern of Salmonella and change over time. The purpose of this research was to determine the in vitro sensitivity pattern of Salmonella typhi to antibiotics chloramphenicol, amoxicillin, and cotrimoxazole in patients of Paediatric Department of RSUD Ulin Banjarmasin. This research was laboratoric descriptive.Out of 37 blood samples of typhoid fever patients in Paediatric Department of RSUD Ulin Banjarmasin, 20 samples were positive of Salmonella typhi isolate and the samples had undergone sensitivity test to antibiotic chloramphenicol, amoxicillin, and cotrimoxazole. This research was carried out with Kirby-Bauer diffusion method. Result interpretation was based on the formation radical zone of bacteria growth around antibiotic disk and it was compared to the standards of sensitivity by Clinical and Laboratory Standards Institute (CLSI) 2011. The results of this research showed that Salmonella typhi was sensitive to chloramphenicol, (65%); amoxicillin, (15%); and cotrimoxazole, (80%); resistance to chloramphenicol, (10%); amoxicillin, (85%); and cotrimoxazole, (20%); and intermediat to chloramphenicol, (25%). The results of this research suggested that antibiotics chloramphenicol and cotrimoxazole were still sensitive to the bacteria Salmonella typhi, whereas amoxicillin was already resistant. Keywords: amoxicillin, chloramphenicol, cotrimoxazole, Salmonella typhi. ABSTRAK: Angka kejadian demam tifoid pada anak yang masih tinggi khususnya di Bagian Anak RSUD Ulin Banjarmasin, sehingga diperlukan pengobatan yang efektif dan efesien. Uji sensitivitas terhadap organisme yang cenderung mengalami resistensi seperti Salmonella typhi sangatlah penting karena pada masing-masing daerah mempunyai pola sensitivitas Salmonella yang berbeda dan berubah seiring waktu. Tujuan dari penelitian ini adalah untuk mengetahui pola sensitivitas in vitro Salmonella typhi terhadap antibiotik kloramfenikol, amoksisilin, dan kotrimoksazol pada pasien yang berada di Bagian Anak RSUD Ulin Banjarmasin. Penelitian ini bersifat deskriptif laboratorik. Dari 37 sampel darah penderita demam tifoid di Bagian Anak RSUD Ulin Banjarmasin didapatkan 20 isolat positif Salmonella typhi dan telah dilakukan uji sensitivitas terhadap 3 jenis antibiotik yaitu kloramfenikol, amoksisilin, dan kotrimoksazol. Penelitian ini dilakukan dengan metode difusi Kirby-Bauer. Interpretasi hasil berdasarkan pada terbentuknya zona radikal pertumbuhan bakteri di sekitar disk antibiotik dan dibandingkan dengan standar sensitivitas menurut Clinical and Laboratory Standards Institute (CLSI) tahun 2011. Hasil penelitian menunjukkan bahwa Salmonella typhi sensitif terhadap kloramfenikol, (65%); amoksisilin, (15%); dan kotrimoksazol, (80%); resisten terhadap kloramfenikol, (10%); amoksisilin, (85%); dan kotrimoksazol, (20%); dan intermediat terhadap kloramfenikol, (25%). Hasil penelitian ini menunjukkan antibiotik kloramfenikol dan kotrimoksazol masih sensitif terhadap kuman Salmonella typhi, sedangkan amoksisilin sudah resisten. Kata-kata kunci: amoksisilin, kloramfenikol, kotrimoksazol, Salmonella typhi.
Perbandingan Daya Hambat Ekstrak Etanol Dengan Sediaan Sirup Herbal Buah Belimbing Wuluh (Averrhoa bilimbi L.) Terhadap Pertumbuhan Shigella dysenteriae In Vitro Intan Kusuma Dewi; Joharman Joharman; Lia Yulia Budiarti
Berkala Kedokteran Vol 9, No 2 (2013)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v9i2.949

Abstract

ABSTRACT: Sour carambola (Averrhoa bilimbi, L) fruit has antibacterial effect to Shigella dysenteriae. Shigella dysentriae is Gram-negative bacteria caused shigellosis and bloody diarrhea in human. Sour carambola can be used as extract and herbal syrup. This research aims to compare the inhibitory effect between ethanol extract and herbal syrup of sour carambola fruit to against Shigella dysenteriae in vitro. The concentration of ethanol extract and herbal syrup were 60 %,70%, 80% and 90%. Antibacterial effect was tested by Kirby- Bauer diffusion method on Mueller Hinton media and measure the inhibitory zone of  Shigella dysenteriae. The result of inhibitory zone was tested by Kruskal-Wallis and Mann-Whitney post hoc tests with 95% significance level showed  that ethanol extract and herbal syrup of sour carambola showed the differences in concentration of 60% (p < 0,05). The phytochemical screening result showed that ethanol extract of sour carambola contains  flavonoid, saponin, alkaloid and steroid. Keywords: Averrhoa bilimbi, L., ethanol extract, herbal syrup, Shigella dysenteriae ABSTRAK: Buah belimbing wuluh (Averrhoa bilimbi, L.) terbukti memiliki aktivitas antibakteri terhadap Shigella dysenteriae. Shigella dysenteriae merupakan bakteri penyebab shigellosis atau disentri basiler. Buah belimbing wuluh dapat digunakan dalam bentuk ekstrak dan sirup. Penelitian ini bertujuan untuk mengetahui adanya perbedaan daya hambat antara ekstrak etanol dengan sediaan sirup herbal buah belimbing wuluh dalam menghambat pertumbuhan Shigella dysenteriae in vitro. Konsenterasi ekstrak etanol dan sirup herbal buah belimbing wuluh yang digunakan adalah 60%, 70%, 80% dan 90%. Uji antibakteri dilakukan menggunakan metode difusi Kirby-Bauer dengan media Mueller- Hinton dan dilakukan pengukuran zona hambat Shigella dysenteriae. Hasil zona hambat yang terbentuk diuji menggunakan Kruskal Wallis dan post hoc Mann Whitney dengan tingkat kepercayaan 95% dan menunjukkan bahwa ekstrak etanol dan sediaan sirup herbal buah belimbing wuluh memiliki perbedaan bermakna dalam menghambat Shigella dysenteriae pada konsenterasi 60% (p<0,05). Hasil skrining fitokimia ekstrak etanol buah belimbing wuluh menunjukkan adanya kandungan flavonoid, saponin, alkaloid dan steroid.  Kata-kata kunci: Averrhoa bilimbi, L., ekstrak etanol, Shigella dysenteriae, sirup herbal
Uji Sensitivitas Isolat Bakteri Pasien Urolithiasis di Ruang Perawatan Bedah Rsud Ulin Banjarmasin terhadap Antibiotik Terpilih Strata Pertiwi; Eka Yudha Rahman; Lia Yulia Budiarti
Berkala Kedokteran Vol 10, No 1 (2014)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v10i1.929

Abstract

ABSTRACT: Urinary tract infection (UTI) is defined as the presence of microorganisms in urine which is marked with significants bacteriuria. Urinary tract infection is very common condition that occurs in both women and men in all ages. Urinary tract stone (Urolithiasis) can lead to the development of bacteriuria. Bacterial resistance to antibiotics has long recovery from UTI. The aim of this research was to find out bacterial sensitivity urinary tract infection in patients urolithiasis to selected antibiotic in Surgical Treatment Ulin General Hospital Banjarmasin period Juni-Agustus 2013. The selected antibiotics were ceftriaxone, levofloxaxin and gentamicin. The research was a descriptional research. The subject of this research is all patients urolithiasis with complication urinary tract infection in Surgical Treatment Ulin General Hospital Banjarmasin period Juni-Agustus 2013. The sampling technique in this research was consecutive method. The sensitivity test to antibiotic test in the research used Kirby-Bauer method and analyzed according to CLSI 2011 standard. Based of the research can be concluded that bacteria that sensitive to selected antibiotics in succession is levofloxaxin 61,54%, seftriaxone 15,38% and gentamicin 15,38%. Percentage of bacteria that resisten to antibiotic seftriaxone 23,8%. Keywords: bacteriuria, gentamicin, urinary tract infection (UTI), in vitro, levofloxaxin, seftriaxone, urolithiasis ABSTRAK: Infeksi saluran kemih (ISK) didefinisikan sebagai adanya mikroorganisme dalam urin yang ditandai dengan bakteriuria bermakna. Infeksi saluran kemih merupakan kondisi yang sangat umum terjadi baik pada wanita maupun pria pada semua usia. Batu saluran kemih (urolithiasis) dapat menyebabkan perkembangan bakteriuria. Resistensi bakteri terhadap antibiotik menyebabkan lamanya penyembuhan dari ISK. Penelitian ini bertujuan untuk mengetahui sensitivitas bakteri penyebab ISK pada pasien urolithiasis terhadap antibiotik terpilih di Bagian Perawatan Bedah RSUD Ulin Banjarmasin periode Juni-Agustus 2013. Antibiotik terpilih yaitu seftriakson, levofloksasin dan gentamisin. Penelitian ini merupakan penelitian deskriptif murni sensitivitas isolat bakteri Escheriachia coli, pseudomonas sp., dan proteus sp. dari pasien urolithiasis dengan ISK terhadap antibiotik uji terpilih. Subjek penelitian ini adalah seluruh pasien urolithiasis dengan komplikasi infeksi saluran kemih di ruang perawatan bedah RSUD Ulin Banjarmasin periode Juni-Agustus 2013. Teknik pengambilan sampel pada penelitian ini adalah consecutive method. Uji sensitivitas antibiotik pada penelitian ini menggunakan metode Kirby-Bauer dan dianalisa sesuai dengan standar CLSI 2011. Berdasarkan penelitian yang telah dilakukan dapat disimpulkan bakteri yang sensitif terhadap antibiotik terpilih secara berturut-turut adalah levofloksasin 61,54%, seftriakson 15,38%, dan gentamisin 15,38%. Persentase bakteri yang resisten terhadap antibiotik seftriakson 23,8%. Kata-kata kunci: bakteriuria, infeksi saluran kemih (ISK), in vitro, levofloksasin, gentamisin, seftriakson, urolithiasis
Perbandingan Sensitivitas Bakteri Aerob Penyebab Otitis Media Supuratif Kronik Tipe Benigna Aktif Tahun 2008 Dan 2012 Hafizah Hafizah; Nur Qamariah; Lia Yulia Budiarti
Berkala Kedokteran Vol 9, No 1 (2013)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (249.21 KB) | DOI: 10.20527/jbk.v9i1.920

Abstract

ABSTRACT: Active benign chronic suppurative otitis media (ABCSOM) was a chronic infection of middle ear with the perforation of tympanic membrane and history of  drainage (otorrhea) for more than 2 months. The aim of this research is to compare the bacteria sensitivity to the antibiotic between 2008 and 2012. The antibiotics used for this research are ciprofloxacin, gentamicin, chlorampenicol and polymixyn B. This is an observational analytic research. The bacteria sensitivity was examined with Kirby-Bauer diffusion method and were converted using the standard of CLSI. The data were analyzed with Kolmogorov smirnov and Fisher test. The results has showed that in 2012 ciprofloxacin has 100% sensitivity, gentamicin has 98.2%,  chloramphenicol has 81,9% and polymyxin B has 30,8%, while the result in 2008 showed chloramphenicol has 86,1% sensitivity, gentamicin has 40,3% and polymyxin B has 13,8%. Data analysis using Kolmogorov smirnov and Fisher test with 95% confidence level showed that there is significant difference between the sensitivity of Pseudomonas aureginosa and Staphylococcus aureus to gentamicin and there is no significant difference in the other comparisons. It has been concluded that the most sensitive antibiotics in 2012 is ciprofloxacin and there is a significant difference in sensitivity of Staphylococcus aureus and Pseudomonas aureginosa to gentamicine in 2008 and 2012. Keywords : CSOMBA,  sensitivity of antibiotics, resistence of antibotics, sensitivity test of bacteria ABSTRAK: Otitis Media Supuratif Kronik tipe Benigna Aktif (OMSKBA) adalah infeksi kronis pada telinga dengan perforasi membran timpani dan riwayat keluarnya otorea lebih dari 2 bulan. Penelitian ini dilakukan untuk membandingkan sensitivitas bakteri penyebab OMSKBA terhadap beberapa antibiotik pada tahun 2008 dan 2012. Antibiotik yang digunakan adalah siprofloksasin, gentamisin, kloramfenikol dan polimiksin B. Penelitian ini bersifat observasional analitik. Sensitivitas bakteri diuji dengan metode Kirby Bauer dan hasilnya dikonversikan dengan standar CLSI. Hasil penelitian pada tahun 2012 didapatkan sensitivitas dari siprofloksasin 100%; gentamisin 98,2%; kloramfenikol 81,9%; dan Polimiksin B 30,8%. Hasil Penelitian pada tahun 2008 didapatkan sensitivitas dari kloramfenikol 86,1%; gentamisin 40,3%; dan polimiksin B 13,8%. Hasil analisis data menggunakan uji Kolmogorov-Smirnov dan Fisher dengan tingkat kepercayaan 95% memperlihatkan adanya perbedaan pada sensitivitas bakteri Staphylococcus aureus dan Pseudomonas aureginosa terhadap gentamisin, sedangkan pada hasil lainnya tidak didapatkan adanya perbedaan. Dapat simpulkan bahwa antibiotik yang paling sensitif pada tahun 2012 adalah siprofloksasin dan pada uji analisis terdapat perbedaan sensitivitas yang bermakna pada bakteri Staphylococcus aureus dan Pseudomonas aureginosa terhadap antibiotik gentamisin pada tahun 2008 dan 2012. Kata-kata Kunci : OMSKBA, resistensi antibiotik, sensitivitas antibiotik, uji sensitivitas bakteri
Co-Authors A.A. Ketut Agung Cahyawan W Abdurahman Wahid Agung Biworo Agung Biworo Agung Biworo Ahdadia, Huda Aisyah Aisyah Akbar Rihansyah Akbar Rihansyah, Akbar Alfi Yasmina Alfi Yasmina Alfi Yasmina Alfia Fitriani Alfia Fitriani, Alfia Alshazil, Renata Seikh Amalia, Maulidia Khairada Amalya, Khalida Zikra Amiratun Naillah Anward, Aliy Arivin Ari Yunanto Arietama, George Armanda, Ferdio Aulia Nalar, Gusti Ayu Apriliani Ayu Dewi Pertiwi Ayu Septiana Azhari, Nazla Puteri Bhisma Ridho Romadhon Borneo Yuda Pratama Chyntia Devi, Made Putri Dastin Andre Davi’ Qowiyul Ali Dayana, Puteri Dayani, Nor Ella Debby Saputera, Debby Derlin, Ellanda Permata Desy Elisa Kismiliansari Desy Elisa Kismiliansari, Desy Elisa Devin, Firdi Dewi Nurdiana Dhian Ririn Lestari Dhian Ririn Lestari, Dhian Ririn Diah Puspita Rifasanti Diah Puspita Rifasanti Dini Permata Sari Dita Permatasari Dita Permatasari Dwi Nur Rachmah Dwi Nur Rachmah Edi Hartoyo Edi Hartoyo Edyson Edyson Edyson Edyson Edyson Edyson, Edyson Eka Yudha Rahman Eka Yudha Rahman Erida Widyamala Erida Wydiamala Erida Wydiamala Erwin Rosadi Erwin Rosadi, Erwin Fachriyad, Muhammad Fahdyannoor, Fahdyannoor Fahdyanoor Fahmi, Yafi Farida Heriyani Farida Heriyani Farida Heriyani Farida Raudah Farida Raudah, Farida Ferdio Armanda Galuh Eka Suryani Ghina Salsabila Gusti Aulia Nalar Hafiz Rakhmatullah Hafizhah, Ghina Hardiyanti Ruslan Hayatun Nufus Herawati Herawati Hikmah Ika Darmayanta Husna Dharma Putera Husna Dharma Putera, Husna Dharma Husnul Khatimah Ichrom Nahzi, Muhammad Yanuar Ihsanti, Shofia Hilwa Ihya Ridlo Nizomy Ihya Ridlo Nizomy, Ihya Ridlo Ikhwanda Angga L. Ikhwanda Angga L., Ikhwanda Angga Indah Ramadhan Intan Kusuma Dewi Irma Zufira Isnaini Isnaini Isnaini Isnaini Isnaini Joharman Joharman Khatimah, Husnul Khatimah3, Husnul Lena Rosida Lie Vanny Leono Lutfia Papita Derizky Rahmayanti M. Rizki Valian Akbar M. Rizki Valian Akbar, M. Rizki Valian Maharani Laillyza Apriasari Moehammad Rezaldi Panesa Mohammad Bakhriansyah Muhammad Baihaqi Siddik Muhammad Bayu Fernanda Muhammad, Fadil Muthmainah, Noor Nadhila Nadhila Nadya Azzahra, Nadya Nadya Salsabila Nafiah Syella, Nafiah Nafilah Syella Nafilah Syella, Nafilah Najiya Ulfa Nasution, Naulita Sari Nazla Puteri Azhari Nida Nurkhalishah Nisa, Rohmatun Noor Fathimah Zohra Noormuthmainah, Noormuthmainah Nor Admi Zayanti Nor Ella Ella Dayani Norma Sari Normaida Novianti Novita Pratiwi Nur Adnia Nur Azmina Aisyah Nur Qamariah Nur Salsabila Apriliani Risma Putri Nurlaili Rafina Nurwafa, Nurwafa Nurzahida, Gusti Nadya Pauline Surya Kurniati Prenggono, Muhamad Darwin Puspa Astri Sella Putra, Andifa Anugerah Putri Putri, Putri Qiptiah, Putri Mariatul Rahmah, Resvi Amalia Rahmiati Rahmiati Raymona Dewi Ginarti Ridhoni, Muhammad Zaki Rohmatun Nisa S., Nur Almira R. Safaana, Aurora Savitri, Dwiana Shahiba Inayati Maghfira Siddik, Muhammad Baihaqi Silvan Juwita Siti Kaidah Siti Kaidah Solly Aryza Sonya Esti Kholifa Sri Hayati Nufaliana Sri Hayati Nufaliana, Sri Hayati Sri Widyarsi Strata Pertiwi Strata Pertiwi, Strata Sukma Noor Akbar Talitha Maghfira Ramadhinta Talitha Maghfira Ramadhinta, Talitha Maghfira Thea Shagita Ulfa, Najiya Vania Puspitasari Sangadi Wahyuni A Wahyuni A, Wahyuni Widiantoro Saputro Widya Nursantari Wydiamala, Erida Wydiamala, Erida Yulia, Noor Zafira Aisyah Putri Zohra, Noor Fathimah Zufira, Irma