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All Journal International Journal of Public Health Science (IJPHS) Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Jurnal Pendidikan Biologi Undiksha Jurnal Kedokteran Brawijaya Majalah Kedokteran Bandung Biota: Jurnal Ilmiah Ilmu-Ilmu Hayati Medula Indonesian Journal of Urology Bioeksperimen: Jurnal Penelitian Biologi Jurnal Penelitian Pertanian Terapan Paediatrica Indonesiana Jurnal Biologi Tropis Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Kesehatan Jurnal Ilmiah Biologi Eksperimen dan Keanekaragaman Hayati (J-BEKH) BIO-EDU: Jurnal Pendidikan Biologi Jurnal Ilmu Medis Indonesia Bioma : Jurnal Biologi dan Pembelajaran Biologi IJIS Edu : Indonesian Journal of Integrated Science Education JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine
Hendri Busman
Jurusan Biologi Fakultas Matematika dan Ilmu Pengetahuan Universitas Lampung
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Effects of soy plus zinc supplementation on growth and kidney health in Wistar rats: Implications for childhood stunting prevention Yuniastini, Yuniastini; Purwati, Purwati; Rahmadi, Antun; Sulastri, Sulastri; Wiratmoko, Wien; Prasetio, Iradah Lia; Busman, Hendri; Al Hafidz, Muhammad; Mz, Fannia Khairani; Hak, Mohammad Hafid
International Journal of Public Health Science (IJPHS) Vol 15, No 1: March 2026
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v15i1.26895

Abstract

Zinc deficiency can cause growth and health problems, whereas protein from soy sources contributes to essential nutritional intake. This study aimed to evaluate the effects of soy plus zinc (SPZ) supplementation on growth and kidney health in Wistar rats. This study used a randomized controlled trial design with 24 rats divided into five treatment groups, including a control group. SPZ supplementation was administered daily for 14 days with varying zinc doses (0.020 mg and 0.035 mg per gram of body weight) and palatability enhancement using vanilla flavoring. Data obtained through measurements of initial and final body weights and kidney weights were analyzed using ANOVA to determine significant differences between groups. The results showed that SPZ supplementation positively contributed to growth, as evidenced by a significant increase in the final weight of rats compared to their initial weight (p < 0.05). Histological analysis of the kidneys indicated no visible structural damage, and the average increase in kidney weight was approximately 26.5%. The combination of soy and zinc in SPZ was shown to have a synergistic effect that benefits the development and kidney health of rats, demonstrating its potential application in the context of animal nutrition.
Keberhasilan Pleurodesis Bleomisin Pada Pneumotoraks Spontan Sekunder Berulang Akibat Tuberkulosis Paru: Laporan Kasus Mustofa, Syazili; Fitri, Reggina Annisa; Choerunnisa, Nida; Soemarwoto, Retno Ariza; Putri, Giska Tri; Busman, Hendri
Jurnal Ilmu Kedokteran dan Kesehatan Vol 13, No 3 (2026): Volume 13 Nomor 3
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v13i3.23187

Abstract

Pneumotoraks spontan sekunder merupakan komplikasi serius tuberkulosis paru dengan risiko kekambuhan yang tinggi. Dilaporkan seorang perempuan 17 tahun dengan tuberkulosis paru yang mengalami pneumotoraks berulang meskipun telah dilakukan pemasangan chest tube. Pasien kemudian menjalani pleurodesis menggunakan bleomisin, dengan hasil resolusi klinis dan radiologis lengkap tanpa kekambuhan selama 2 bulan follow-up. Temuan ini menunjukkan bahwa pleurodesis bleomisin berpotensi menjadi pilihan terapi yang efektif pada pneumotoraks spontan sekunder berulang terkait tuberkulosis, terutama pada kasus yang tidak responsif terhadap chest tube. Secara klinis, pendekatan ini dapat dipertimbangkan sebagai alternatif minimal invasif pada pasien dengan kontraindikasi tindakan bedah atau risiko kekambuhan yang tinggi.
Analysis of Serum Glutamate Pyruvate Transaminase (SGPT) and Serum Glutamate Oxaloacetate Transaminase (SGOT) Levels in the Blood of Rat Offspring (Rattus norvegicus) Treated with Soybean (Glycine max L.) Extract and Zinc Hafidz, Muhammad Al Hafidz; Busman, Hendri; Kanedi, M. Kanedi; Widiastuti, Endang Linirin
Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 14 No. 1 (2026): JAMBI MEDICAL JOURNAL: Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jmj.v14i1.41788

Abstract

Background: The liver is the largest metabolic organ and plays an important role in the body. Nutritional fulfilment is one factor in maintaining liver health. Liver function can be evaluated by measuring the levels of SGPT and SGOT enzymes in the blood. Soybean juice and zinc can support liver health by keeping SGPT and SGOT enzyme levels normal. Methods: This study was conducted between October and December 2024 at the Zoology Laboratory of the University of Lampung. This study used a Completely Randomized Design (CRD) included four treatment groups. Each treatment included five mice: control (K), treatment 1 (P1)- induced Soybean juice 0,6 mL/kg body weight (P2) induced Soybean 0,3 mL/kg body weight and Zinc 0,3 mL/kg body weight, and (P3) induced Soybean 0,6 mL/kg body weight and Zinc 0,6 mL/kg body weight for 14 days. Normal and homogeneous data were analyzed using analysis of variance (ANOVA) to determine whether the treatment's effect was significant. Differences were considered statistically significant at p < 0.05. Duncan's multiple interval post hoc test (=5%) was used to identify the most effective treatment. Result: Based on the results of the one-way ANOVA test with a 95% confidence interval, the average SGPT and SGOT levels in the K, P1, P2, and P3 treatments differ significantly. The average SGPT levels above show that the P2 and P3 groups experienced a significant decrease compared to the K and P1 treatments. Conclusion: Analysis of variance (ANOVA) showed that administering soya juice and zinc at an optimum dose of 1.2 mL/kg body weight can affect and maintain normal SGPT and SGOT levels.
Co-Authors Adli, Farhan Kamali Ajeng Pawesti, Ammanda Sadiva Al Hafidz, Muhammad Alqoriani A, Ostarica Amani Raya, Latansa Ananta, Yoga Andriani, Silvia Angelia, Tisa Arofah, Nur Lailatul Ayu Ayssca Besty Prastiwy, Ayu Ayssca Azizah, Nailul Bayu Putra DJ Bilqis, Khorina Fatin Cahyani, Endang Nur Choerunnisa, Nida Dyah Wulan Sumekar Rengganis Wardani Endah Setyaningrum, Endah Ernawiati, Eti Fitri, Reggina Annisa Gina Dania Pratami, Gina Dania Ginting, Bisart Giska Tri Putri Hadibrata, Exsa Hafidz, Muhammad Al Hafidz Hak, Mohammad Hafid Hanifah, Farah Hendri Tarigan S Indri Windarti Indriyani Indriyani Indriyani Intanri Kurniati Iswandi Darwis Jausal, Anisa Nuraisa Justisia, Adilla Kanedi, M. Kanedi Karina, Salwa Al Khairun Nisa Kurniawaty, Evi Kurniawaty, Evi Kurniawaty Kusuma Handayani, Kusuma Leni Ervina, Leni Maulana, Rifadly Yusril Muhammad Ilyas Muhartono Muhartono Muhartono Sudarmo Kasban Mumtazah, Dzul Fithria Mz, Fannia Khairani NA, Ahmad Mufid Nuning Nurcahyani Nursidiq, Iqbal Muhammad Rafi Prasetio, Iradah Lia Purwati Purwati Puspa, Egita Windrianatama Putri, Lolyta Mutiara Rahmadi, Antun Rahmanisa, Soraya Rahmanisa Ramdini, Dwi Aulia Rosa, Emantis RR. Ella Evrita Hestiandari Safitri, Dewi Restika Ayu Sahroni, Mizan Sangging, Putu Ristyaning Ayu Sarasati, Filia Sembiring, Rinawati Septiani, Linda Soemarwoto, Retno Ariza Sulastri Sulastri Susanto, Gregorius Nugroho Susianti Susianti Sutyarso Sutyarso Sutyarso Syakir, Muhammad Addin Syarif, Muhammad Reza Syazili Mustofa Tri Putri, Giska Utami, Hanifa Fauzia Widiastuti, Endang Linirin Wiratmoko, Wien Yolanda, Jennifer Ester Yulia Sari, Umi Yuniastini, Yuniastini Yuningrum, Hesti