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All Journal ACTA VETERINARIA INDONESIANA Hemera Zoa Jurnal Sain Veteriner Jurnal Veteriner Veterinary Biomedical and Clinical Journal Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal Pusat Inovasi Masyarakat Jurnal Veteriner dan Biomedis Current Biomedicine Asian Journal of Social and Humanities Indonesian Journal of Jamu Jurnal Veteriner
Lina Noviyanti Sutardi
Institut Pertanian Bogor
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences Veterinary

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PAT-3 In Vitro Growth Inhibition Activities of Natural (nCaIFN) and Recombinant (rCaIFN) Canine Interferons on Three Different Tumor-Derived Cell Lines Bambang Pontjo Priosoeryanto; Rizki Rostantinata; Eva Harlina; Lina Noviyanti
Hemera Zoa Proceedings of the 20th FAVA & the 15th KIVNAS PDHI 2018
Publisher : Hemera Zoa

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Abstract

Recently, from many kinds of diseases one could be counted is a tumor disease. Tumor is a degenerative disease that involved many biological pathways within the host. A tumor or neoplasm can be defined as a disturbance of growth characterized by excessive, abnormal and uncontrolled proliferation of transformed or altered cell(s) at  one or more primary points within the host, and frequently at  one or more metastatic sites (Priosoeryanto, 1994).The treatment of tumor is mostly by medical surgery which usually combined with chemotherapeutic agent(s), unfortunately the using of chemotherapeutic agent can develop a seriously side effect to the treated-patients. Biological substances like interferon (IFN) known as anti-virus agent is also one of promising candidate for treating or preventing of tumor disorders.Feline and canine squamous cell carcinoma is one of tumor type that often found in cat and dog, and mostly develop to a very aggressive disorder. The using of in vitro cell culture is a way to avoid the use of live animals on the study of tumors especially the study of antitumor agent due to can mimic the in vivo condition.  The aim of the present study is to examine the growth inhibition activity of natural and recombinant canine interferon in order to find the suitable biological substances for combating tumor disorder especially in the field of veterinary medicine and also as an information for the development of tumor treatment in the human medical side.
PAT-8 Antiproliferation Activity of Keladi Tikus (Typhonium flagelliforme) Leaves Ethanol Extract on MCA- B1 and MCM-B2 Tumor – Derived Cell Lines In Vitro Riski Rostantinata; Bambang Pontjo Priosoeryanto; Eva Harlina; Waras Nurcholis; Lina Noviyanti; Rachmi Ridho
Hemera Zoa Proceedings of the 20th FAVA & the 15th KIVNAS PDHI 2018
Publisher : Hemera Zoa

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INTRODUCTIONTumor  is  a  degenerative disease  as  the second agent cause of death in human. This disease is caused by disturbances of cell’s growth that show alteration and uncontrolled of cells proliferation. The uncontrolled of cells proliferation is also accompanied by penetration of that cells into others tissue and develop on it. Removed of tumor is usually done by operation or chemotherapy. Alternative treatment that can be used is herbal treatment. Typhonium flagelliforme known as “Keladi Tikus” in Indonesia; is known has a chemopreventive effect (2). Other researchers also show flavonoid glucoside of T. flagelliforme (1) can induce the activity of apoptosis in colon cancer cells (5). The aim of this study is to examine the in vitro anti-proliferation activity of Typhonium flagelliforme leaves ethanol extract on MCA- B1and MCM-B2 cell line.
Co-Authors Adi Winarto Alifin Wisnu Ananta Alpayet, Rahmat Amaq Fadholly Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Anggraeni, Henny Endah Anggraini, Lutvi Anisa Rahma, Anisa Anisa, Rahma Anita Esfandiari April Hari Wardhana April Hari Wardhana Ardi Sandriya Aulia Andi Mustika Aulia Andri Mustika Aulia Mustika Bachmid, Salma Safitri Bambang Pontjo Priosoeryanto Bayu Febram Prasetyo Budiono, Novericko Ginger Christina Clarice Leksono Deni Afrizal Dhiya Puja Ramadhan Diah Nugrahani Pristihadi Diaz, Fariz Arrachman Dodi Darmakusuma Dodi Darmakusumah Ekowati Handharyani Elpita Tarigan Elpita Tarigan Elpita Tarigan Esti Dhamayanti Eva Harlina Fedik Abdul Rantam Fitri Ariyani Fitri, Arni Diana Geby Magdalena Simanjuntak Guna Prajanto Gunanti . Hadri Latif Hamdika Yendri Hamdika Yendri Hamdika Yendri Putra Hamdika Yendri Putra IETJE WIENTARSIH Inayati ilmi Kamilatun Nisa Khonsa Khonsa Kusdiantoro Mohamad Kusdiantoro Muhamad Leliana Nugrahaning Widi Leliana Nugrahaning Widi Leliana Widi Leliana Widi Lingga Surya Maret Daulay Madyastuti, Rini Maret Daulay, Lingga Surya May, Ng U Mufida, Anis Arifatu Muhammad Bintang Nababan, Ratna Kristiani Nabilah, Avida Shahnaz Nina Indria Afifah Nisrina Nurmahfuzhah Nurdiansyah, Rio Dwi Haryadi Nuzul Asmilia Nuzul Asmilia Purohita, Adwisto Saktika Rachmi Ridho Raphaella widiastuti Rasyid, Baharun Ridi Arif Riki Siswandi Rindy Fazni Nengsih Rindy Fazni Nengsih Rindy Fazni Nengsih Rindy Fazni Nengsih Rini, Dian Cipta Risa Tiuria Riski Rostantinata Riski Rostantinata Rizki Rostantinata Safitri, Nadiya Santosa, Alfian Shabrina Marsha Shabrina Rizki Ahadiah Silmy Kamila Widyanti Siti Rabi’ah SM Leluala Subangkit, Mawar Supiyani, Atin Sus Derthi Widhyari Trioso Purnawarman Utami Idha Pangesti Waras Nurcholis Wasmen Manalu Wiwin Winarsih Yessy Anastasia Yusa Irarang Yusa Irarang Yusa Irarang