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All Journal Indonesian Journal of Cancer Chemoprevention Majalah Obat Tradisional MPI (Media Pharmaceutica Indonesiana) Abdimas Talenta : Jurnal Pengabdian Kepada Masyarakat JSFK (Jurnal Sains Farmasi & Klinis) PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Viva Medika: Jurnal Kesehatan, Kebidanan dan Keperawatan Majalah Kesehatan Pharmamedika Jurnal Ners Indonesian Journal of Pharmaceutical and Clinical Research IJOEP : International Journal of Ecophysiology International Journal Of Science, Technology & Management (IJSTM) Unri Conference Series: Community Engagement JOURNAL LA MEDIHEALTICO Cakradonya Dental Journal Journal of Pharmaceutical and Sciences.
Aminah Dalimunthe
Departement Of Pharmacology, Faculty Of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia
Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Transportation Veterinary

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Pengaruh Intervensi Apoteker terhadap Pengetahuan, Tingkat Kepuasan dan Outcome Terapi Pasien Swamedikasi Commond Cold di Apotek Kasih Agape Tarigan, Eunike Victorita; Wiryanto, Wiryanto; Dalimunthe, Aminah
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 3 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i3.941

Abstract

Self-medication for minor illnesses such as the common cold is generally done by the community. In situations like this, the role of pharmacists is very important in providing education to improve patient safety. This study aims to analyze the effect of pharmacist intervention (pretest-posttest) on the level of knowledge and outcome of self-medication therapy for common cold patients at Kasih Agape Pharmacy Medan. This study used a quasi-experimental design with a one-group pretest-posttest design approach on the knowledge and outcome indicators, while the patient satisfaction indicator used a descriptive quantitative research design. The sample consisted of 50 patients who were in the intervention group (pretest-posttest), randomly selected using a purposive sampling technique. The intervention was given in the form of pharmacist education and counseling. Data were collected using a questionnaire that had been tested for validity and reliability. The results of the analysis showed that there was a significant increase in the level of knowledge (p <0.05) and outcome of therapy (p <0.05) in the intervention group compared to the pretest and posttest. These results can also be seen as increasing patient knowledge, and the outcome of therapy can have an impact on increasing patient satisfaction. This study shows that pharmacist intervention can effectively improve the quality of self-medication for the common cold in patients. This study emphasizes the importance of the active role of pharmacists in providing education to support safe, rational drug use and improve therapeutic outcomes.
EVALUASI ORGANOLEPTIK PERMEN HERBAL KENCUR (Kaempferia galanga L rhizoma) DAN JAHE MERAH (Zingiber officinale var rubrum rhizoma) Dalimunthe, Aminah; Masfria; Sumaiyah
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 3 No. 2 (2018): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (571.036 KB) | DOI: 10.32734/abdimastalenta.v3i2.4117

Abstract

Tujuan penelitian ini adalah untuk mengetahui daya terima masyarakat berdasatkan tingkat kesukaan rasa, aroma, warna, dan tekstur permen herbal dari kencur dan jahe merah . Penelitian ini dilakukan secara eksperimental menggunakan metode analisis statistik deskriptif. Hasil penelitian, menunjukkan bahwa tidak ada perbedaan signifikan terhadap tingkat kesukaan rasa, aroma, warna dan tekstur permen herbal dari kencur dan jahe merah (P>0,05) sehingga dapat disimpilkan bahwa masyarakat meyukai permen herbal dari kencur dan jahe merah.
Hepatoprotective Activity of Ethanol Extract of Mobe Leaves (Artocarpus lacucha Buch-Ham.) on Total Bilirubin, ALT, and AST Levels, and Macropathology of Liver in Rats Induced by Carbon Tetrachloride Lubis, Meiva Amelia; Dalimunthe, Aminah; Sitorus, Panal; Satria, Denny; Lubis, Arga
Viva Medika Vol 17 No 3 (2024)
Publisher : Universitas Harapan Bangsa Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35960/vm.v17i3.1490

Abstract

This study evaluates the hepatoprotective effects of ethanol extract of mobe leaves (Artocarpus lacucha Buch-Ham.) in rats induced with carbon tetrachloride (CCl4). The objective was to determine the extract's efficacy in reducing liver damage markers, specifically total bilirubin, alanine aminotransferase (ALT), and aspartate aminotransferase (AST) levels, and to assess liver macropathology. The ethanol extract was prepared by maceration using 96% ethanol. Results showed that administering 400 mg/kg body weight (BW) of the extract significantly reduced total bilirubin, ALT, and AST levels in CCl4-induced rats. Additionally, liver macropathology observations indicated improved liver conditions in the treatment group. Phytochemical screening revealed bioactive compounds like flavonoids, alkaloids, tannins, saponins, triterpenoids, and glycosides, which are potential antioxidants and hepatoprotective agents. The significant contribution of this research is providing a scientific basis for using mobe leaf extract as a natural hepatoprotective agent, highlighting its potential for safe and effective herbal medicine. Further research and clinical trials are recommended to validate these findings and explore the extract's therapeutic applications.
Teratogenic Effects of Arabica Coffee (Coffea arabica L) on Rats During the Organogenesis Period Reza Destri Anggi; Yuandani; Dalimunthe, Aminah
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 3 No. 2 (2020): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/idjpcr.v3i2.4311

Abstract

The purpose of the research was to evaluate the teratogenic effect caused by theprovision of Arabica coffee solution with variations of 0.36 ml, 0.72 ml and 1.08 ml withpositive control of caffeine at a dose of 300 mg / kg bw to rats during organogenesis. Themeasurement parameters in this study are the appearance of reproduction, externalmalformations and scalal malformations. The results in this study found that theadministration of Arabica coffee solution with a volume of 1.08 ml and caffeine 300 mg /kg bb caused an abnormality in the reproductive appearance of weight loss and body length,whereas for extrenal malformation and scalal malforation no abnormalities were found ineach administration of the solution Arabica coffee and caffeine.  
Hematological and Biochemical Alterations of Andaliman (Zanthoxylum Acanthopodium Dc) with Doxorubicin Induced in White Wistar Rat Prayoga, Andre; Dalimunthe, Aminah; Zumaira; Salim, Emil
International Journal of Ecophysiology Vol. 7 No. 1 (2025): International Journal of Ecophysiology
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijoep.v7i1.20188

Abstract

Doxorubicin, a well-known chemotherapy drug, is associated with cardiac toxicity primarily due to oxidative stress. This oxidative stress leads to the production of reactive oxygen species and a subsequent decline in antioxidant levels. As doxorubicin induces the formation of free radicals and decreases endogenous antioxidants, it triggers various hematological and biochemical abnormalities. Consequently, the use of antioxidants has been proposed as a strategy to mitigate this damage. This study focuses on the administration of ethanol extract from Andaliman (EAF) fruit, recognized for its rich array of metabolites and antioxidant properties, which may serve as a cardioprotective agent against the adverse effects of doxorubicin. The research involved comprehensive observations, including hematological and clinical chemistry examinations. The findings indicate that EAF demonstrates protective effects by enhancing hematological and clinical chemistry parameters in male Wistar rats subjected to doxorubicin. Notably, these improvements were statistically significant when compared to the control group. Given its promising results, further exploration of EAF as a protective agent for hematological and biochemical health warrants attention and development.
Antibacterial Potential Of Ethanol Extract Of Tamarind Seed Bark (Tamarindus indica L.) And Formulation Of Anti-Acne Nanogel Amalyuri, Annisa Ghassani; Reveny, Julia; Dalimunthe, Aminah
International Journal of Science, Technology & Management Vol. 3 No. 3 (2022): May 2022
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v3i3.522

Abstract

Acne is a skin disease that affects a large number of sufferers. Acne occurs due to active oil glands under the skin. This activity is stimulated by androgen hormones. The active compound content of proanthocyanidin is the main compound in the ethanolic extract of tamarind seed bark, which can inhibit the growth of acne-causing bacteria, namely Propionibacterium acnes and Staphylococcus epidermidis. The purpose of this study was to formulate a nanogel from tamarind seed bark extract and test the antibacterial potential of an ethanol extract of tamarind seeds against acne-causing bacteria. The antibacterial potency test consisted of variations in concentration and was 0.5, 1, 5, 25, 50, 75, 100, 125, 150, and 300 (in mg/mL). The concentration of the formulated nanogel preparations was 2.5%, 5%, and 7.5%. The MIC results showed that the minimum inhibitory concentration (MIC) was at a concentration of 1 mg/mL with a zone of inhibition of 6.50 ± 0.44 mm (Propionibacterium acnes) and 6.40 ± 0.10 mm (Staphylococcus epidermidis). The minimum bactericidal concentration (MBC) was at a concentration of 25 mg/mL with a percentage reduction of 98.18% (Propionibacterium acnes) and 98.06% (Staphylococcus epidermidis). The results of the nanogel formulations showed that the particle sizes were 49.88 ± 0.11 nm (Formula I), 51.92 ± 0.09 nm (Formula II), and 59.13 ± 0.10 nm (Formula III). Conclusion The ethanolic extract of tamarind seed bark has effectiveness in inhibiting the growth of acne-causing bacteria and can be formulated as an anti-acne nanogel.
Phytochemical Screening and Antibacterial Potential Ethanol Extract of Kemangi Leaves (Ocimum basilicum L.) Towards Staphylococcus aureus Sanjaya, Angga Nugraha; Harahap, Urip; Dalimunthe, Aminah
International Journal of Science, Technology & Management Vol. 3 No. 6 (2022): November 2022
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v3i6.630

Abstract

An infectious disease is a disease with the highest prevalence in the world, with a great risk of transmission. Staphylococcus aureus is a pathogen that can cause several infectious diseases. The use of kemangi leaves as vegetables can be used as an invention in treating infections caused by bacteria. The purpose of this study was a phytochemical screening test to determine what metabolites are contained and their potential activity against Staphylococcus aureus. The research method is to carry out a qualitative phytochemical screening test using reagents and an antibacterial potential test against Staphylococcus aureus using the Kirby-Bauer method (diffusion agar) with varying concentrations. The results showed that kemangi leaves extract showed positive results on the secondary metabolite compounds, were alkaloids, flavonoids, saponins, tannins, glycosides, and steroids/triterpenoids. The diameter of the inhibition zone at a concentration of 500 mg/mL showed the diameter of the inhibition zone was 11.93 ± 0.25 mm with the strong category group. The conclusion is that the ethanolic extract of kemangi leaves shows the ethanolic extract of kemangi leaves has potential as an antibacterial.
Phytochemical Screening of Cinnamon Bark (Cinnamomum burmanii) (C. Ness & T. Ness) C. Ness ex Blume Ethanol Extract and Antioxidant Activity Test with DPPH (2,2-diphenyl-1-picrylhydrazyl) Method. Sirait, Tri Susanti; Arianto, Anayanti; Dalimunthe, Aminah
International Journal of Science, Technology & Management Vol. 4 No. 1 (2023): January 2023
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v4i1.739

Abstract

Cinnamon (Cinnamomum burmanii) is one of the spices that can be used as cosmetic preparations in the pharmaceutical industry because it contains potent antioxidants. Examples of cosmetic products containing cinnamon are body scrubs, body showers, and moisturizers. This study aimed to determine the antioxidant activity of cinnamon extract using the DPPH method. Cinnamon was extracted using the maceration technique with 96% ethanol solvent, and phytochemical screening was carried out. The results of phytochemical screening from cinnamon bark extract were alkaloids, saponins, tannins, triterpenoids, and flavonoids. Antioxidant activity obtained an IC50 value of 25.35 ppm. Based on these results, the cinnamon extract has a very strong antioxidant activity value.
Pengaruh Konseling Apoteker Terhadap Kepatuhan Penggunaan Obat Antidiabetes dan Kontrol Glikemik pada Pasien Diabetes Nufus, Hayatun; Dalimunthe, Aminah; Wiryanto, Wiryanto
JSFK (Jurnal Sains Farmasi & Klinis) Vol 12 No 2 (2025): J Sains Farm Klin 12(2), August 2025
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.12.2.178-185.2025

Abstract

Controlling blood glucose is paramount in diabetes management, yet medication non-adherence often hinders optimal outcomes. This study investigated the impact of pharmacist counseling on Fasting Blood Glucose (FBG) levels and medication adherence in Type 2 Diabetes Mellitus (T2DM) patients within a rural primary healthcare setting. A quasi-experimental pre- and post-test design was employed with 112 T2DM outpatients from Puskemas Simpang Mamplam, Bireuen City, Aceh, Indonesia, from March to April 2024. Medication adherence was assessed using the MARS-10 Questionnaire, and FBG levels were measured via finger prick. The majority of participants were female (79.5%), aged 41-60 (45.5%, mean age 55.70 ± 10.07 years), with secondary education (43.8%), predominantly sedentary/inactive workers (60.7%), and reported low-income (38.4%). Data analysis was performed using the Wilcoxon Signed rank Test. Following counseling, which was provided every two weeks over the two-months period, the mean medication adherence score significantly increased (p < 0.001) from 3.150 ± 0.942 to 8.790 ± 1.297. FBG levels also significantly decreased (p<0.05), from an initial mean of 308.98 ± 72.995 to 220.42 ± 68.547 at two weeks, 162.36 ± 50.191 at four weeks, and 130.00 ± 27.774 at six weeks. These findings suggest that pharmacist counseling significantly improves both medication adherence (p < 0.001) and glycemic control (FBG decrease, p < 0,05) in T2DM patients.
Co-Authors . S, Aminah Ade Sri Rohani Amalyuri, Annisa Ghassani Anjelisa Z. Hsb, Poppy Arfita Sipahutar Arianto, Anayanti Butar, Ririn Anastasia Butar Candrika, Candrika Darmirani, Yosi Denny Satria, Denny Effendy De Lux Putra, Effendy De Lux Embun Suci Nasution Emil Salim Hafid Syahputra Hakim Bangun* Harahap, Rizki Doli Hartama Hayatun Nufus Herawaty Ginting Iksen, Iksen Julia Reveny Khairunnisa Khairunnisa Khairunnisa Lisda Rimayani Lubis, Arga Lubis, Meiva Amelia Lumbanraja, Linnon Bastian M.S, Wiryanto Masfria Muhammad Wahyu, Muhammad Nasri Nasri, Nasri Nasution, Azizah Nazliniwaty Nazliniwaty* Pintauli, Sondang Prayoga, Andre Putri Fiari, Hera Zalia Rexi, Daniel Reza Destri Anggi Sanjaya, Angga Nugraha Simbolon, Rohana Oktofariday Siti Morin Sinaga Sitorus, Panal Sondang Pintauli Sumaiyah Tarigan, Betharina Br Tarigan, Eunike Victorita Tri Susanti Sirait Urip Harahap Vadhila, Mumtaz Wardono, Sri Waruwu, Syukur Berkat Wira Septama, Abdi Wiryanto Wiryanto Wiryanto Yuandani Zumaira