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All Journal Indonesian Journal of Cancer Chemoprevention Majalah Obat Tradisional MPI (Media Pharmaceutica Indonesiana) Abdimas Talenta : Jurnal Pengabdian Kepada Masyarakat PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Viva Medika: Jurnal Kesehatan, Kebidanan dan Keperawatan Majalah Kesehatan Pharmamedika Jurnal Ners Indonesian Journal of Pharmaceutical and Clinical Research IJOEP : International Journal of Ecophysiology International Journal Of Science, Technology & Management (IJSTM) Unri Conference Series: Community Engagement JOURNAL LA MEDIHEALTICO Cakradonya Dental Journal Journal of Pharmaceutical and Sciences.
Aminah Dalimunthe
Departement Of Pharmacology, Faculty Of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia
Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Transportation Veterinary

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Pengaruh Konseling Apoteker Terhadap Pengetahuan Pasien Diabetes di Apotek Kf 27 Medan Butar, Ririn Anastasia Butar; M.S, Wiryanto; Dalimunthe, Aminah
Jurnal Ners Vol. 9 No. 3 (2025): JULI 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v9i3.47397

Abstract

Abstract This study aimed to analyze the effect of pharmacist counseling on the knowledge of patients with Type 2 Diabetes Mellitus (T2DM) at Kimia Farma 27 Pharmacy, Medan. The study employed a quasi-experimental design with a one-group pretest-posttest approach. A total of 112 T2DM patients participated, selected through total sampling. Data were collected using a validated questionnaire administered before and after pharmacist counseling. The results showed a significant increase in the average knowledge score from 3.07 ± 1.69 to 7.36 ± 1.70, with a p-value of 0.000. The direct counseling sessions, supported by written educational materials, effectively improved patients’ understanding. These findings highlight the strategic role of pharmacists in enhancing medication literacy in primary healthcare settings. This intervention serves as a strong foundation for developing standardized pharmacy counseling modules in community pharmacies. Keywords: pharmacist counseling, medication literacy, type 2 diabetes mellitus, patient education, community pharmacy.
IDENTIFICATION AND CHARACTERIZATION OF ANCHOVY (Stolephorus commersonnii) PRODUCED IN TANJUNG TIRAM VILLAGE BATU BARA REGENCY Rexi, Daniel; Pintauli, Sondang; Dalimunthe, Aminah; Nasri, Nasri
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 8 No. 01 (2025): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/idjpcr.v8i01.20636

Abstract

Anchovy is a widely consumed marine food source in Indonesia and has the potential to serve as a vital nutritional resource. This study aimed to analyze the primary nutrient contents of anchovy, including protein, total fat, phosphorus, calcium, and iron levels. Nutritional composition analysis was conducted through laboratory testing using scientifically validated standard methods. The results were analyzed descriptively to provide an overview of the chemical composition of anchovy. The findings revealed that anchovy contains 31.5% protein, indicating its value as a rich source of animal protein. The total fat content was measured at 4.76%, suggesting a relatively low to moderate fat level. Furthermore, phosphorus content was recorded at 227.8 mg/kg, calcium at 2.45%, and iron at 36.1 mg/kg—all essential minerals for physiological functions. Based on these results, anchovy demonstrates strong potential as a highly nutritious local food source that could significantly contribute to meeting the community's nutritional needs.
OPTIMIZED HPLC METHOD FOR SIMULTANEOUS DETERMINATION OF ARTIFICIAL SWEETENERS, PRESERVATIVES, AND CAFFEINE IN CARBONATED SOFT DRINKS Wardono, Sri; Putra, Effendy De Lux; Sinaga, Siti Morin; Dalimunthe, Aminah; Nasri, Nasri
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 8 No. 01 (2025): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/idjpcr.v8i01.20975

Abstract

Sweeteners, preservatives, and caffeine in soft drinks can pose health risks if consumed excessively. This study aimed to develop a method for the simultaneous determination of acesulfame, saccharin, cyclamate, aspartame, caffeine, benzoate, and sorbate in carbonated soft drinks. The analysis was conducted using reversed-phase high-performance liquid chromatography (RP-HPLC) with a dual-wavelength PDA detector (Shimadzu LC-20AD), a C18 column (Shimadzu), and a UV-Vis spectrophotometer (Shimadzu). Standard materials included acesulfame-K, saccharin-Na, cyclamate-Na, aspartame, caffeine, benzoate-Na, and sorbic acid. Samples were obtained from a supermarket in Medan, Indonesia. Optimization parameters included detection wavelength, mobile phase pH, column oven temperature, and mobile phase composition. Validation parameters assessed were linearity, limit of detection (LOD), limit of quantification (LOQ), accuracy, precision, and selectivity. The optimized method employed a mobile phase of phosphate buffer (pH 3.8) and methanol (80:20, v/v) at a flow rate of 0.55 mL/min and column oven temperature of 40 °C. Detection was carried out at 200 nm for cyclamate, caffeine, aspartame, and benzoate, and at 220 nm for acesulfame, saccharin, and sorbate. Validation results showed the method met all requirements, with recovery rates ranging from 95.21% to 99.82%, system suitability values of 1.0%–1.9%, and precision values between 1.65% and 2.48%. The method also demonstrated good selectivity. The concentrations of acesulfame, saccharin, cyclamate, caffeine, benzoate, and sorbate in the analyzed samples did not exceed the maximum permissible limits.
Pengaruh Intervensi Apoteker terhadap Pengetahuan, Tingkat Kepuasan dan Outcome Terapi Pasien Swamedikasi Commond Cold di Apotek Kasih Agape Tarigan, Eunike Victorita; Wiryanto, Wiryanto; Dalimunthe, Aminah
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 3 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i3.941

Abstract

Self-medication for minor illnesses such as the common cold is generally done by the community. In situations like this, the role of pharmacists is very important in providing education to improve patient safety. This study aims to analyze the effect of pharmacist intervention (pretest-posttest) on the level of knowledge and outcome of self-medication therapy for common cold patients at Kasih Agape Pharmacy Medan. This study used a quasi-experimental design with a one-group pretest-posttest design approach on the knowledge and outcome indicators, while the patient satisfaction indicator used a descriptive quantitative research design. The sample consisted of 50 patients who were in the intervention group (pretest-posttest), randomly selected using a purposive sampling technique. The intervention was given in the form of pharmacist education and counseling. Data were collected using a questionnaire that had been tested for validity and reliability. The results of the analysis showed that there was a significant increase in the level of knowledge (p <0.05) and outcome of therapy (p <0.05) in the intervention group compared to the pretest and posttest. These results can also be seen as increasing patient knowledge, and the outcome of therapy can have an impact on increasing patient satisfaction. This study shows that pharmacist intervention can effectively improve the quality of self-medication for the common cold in patients. This study emphasizes the importance of the active role of pharmacists in providing education to support safe, rational drug use and improve therapeutic outcomes.
EVALUASI ORGANOLEPTIK PERMEN HERBAL KENCUR (Kaempferia galanga L rhizoma) DAN JAHE MERAH (Zingiber officinale var rubrum rhizoma) Dalimunthe, Aminah; Masfria; Sumaiyah
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 3 No. 2 (2018): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (571.036 KB) | DOI: 10.32734/abdimastalenta.v3i2.4117

Abstract

Tujuan penelitian ini adalah untuk mengetahui daya terima masyarakat berdasatkan tingkat kesukaan rasa, aroma, warna, dan tekstur permen herbal dari kencur dan jahe merah . Penelitian ini dilakukan secara eksperimental menggunakan metode analisis statistik deskriptif. Hasil penelitian, menunjukkan bahwa tidak ada perbedaan signifikan terhadap tingkat kesukaan rasa, aroma, warna dan tekstur permen herbal dari kencur dan jahe merah (P>0,05) sehingga dapat disimpilkan bahwa masyarakat meyukai permen herbal dari kencur dan jahe merah.
Hepatoprotective Activity of Ethanol Extract of Mobe Leaves (Artocarpus lacucha Buch-Ham.) on Total Bilirubin, ALT, and AST Levels, and Macropathology of Liver in Rats Induced by Carbon Tetrachloride Lubis, Meiva Amelia; Dalimunthe, Aminah; Sitorus, Panal; Satria, Denny; Lubis, Arga
Viva Medika Vol 17 No 3 (2024)
Publisher : Universitas Harapan Bangsa Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35960/vm.v17i3.1490

Abstract

This study evaluates the hepatoprotective effects of ethanol extract of mobe leaves (Artocarpus lacucha Buch-Ham.) in rats induced with carbon tetrachloride (CCl4). The objective was to determine the extract's efficacy in reducing liver damage markers, specifically total bilirubin, alanine aminotransferase (ALT), and aspartate aminotransferase (AST) levels, and to assess liver macropathology. The ethanol extract was prepared by maceration using 96% ethanol. Results showed that administering 400 mg/kg body weight (BW) of the extract significantly reduced total bilirubin, ALT, and AST levels in CCl4-induced rats. Additionally, liver macropathology observations indicated improved liver conditions in the treatment group. Phytochemical screening revealed bioactive compounds like flavonoids, alkaloids, tannins, saponins, triterpenoids, and glycosides, which are potential antioxidants and hepatoprotective agents. The significant contribution of this research is providing a scientific basis for using mobe leaf extract as a natural hepatoprotective agent, highlighting its potential for safe and effective herbal medicine. Further research and clinical trials are recommended to validate these findings and explore the extract's therapeutic applications.
Teratogenic Effects of Arabica Coffee (Coffea arabica L) on Rats During the Organogenesis Period Reza Destri Anggi; Yuandani; Dalimunthe, Aminah
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 3 No. 2 (2020): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/idjpcr.v3i2.4311

Abstract

The purpose of the research was to evaluate the teratogenic effect caused by theprovision of Arabica coffee solution with variations of 0.36 ml, 0.72 ml and 1.08 ml withpositive control of caffeine at a dose of 300 mg / kg bw to rats during organogenesis. Themeasurement parameters in this study are the appearance of reproduction, externalmalformations and scalal malformations. The results in this study found that theadministration of Arabica coffee solution with a volume of 1.08 ml and caffeine 300 mg /kg bb caused an abnormality in the reproductive appearance of weight loss and body length,whereas for extrenal malformation and scalal malforation no abnormalities were found ineach administration of the solution Arabica coffee and caffeine.  
Hematological and Biochemical Alterations of Andaliman (Zanthoxylum Acanthopodium Dc) with Doxorubicin Induced in White Wistar Rat Prayoga, Andre; Dalimunthe, Aminah; Zumaira; Salim, Emil
International Journal of Ecophysiology Vol. 7 No. 1 (2025): International Journal of Ecophysiology
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijoep.v7i1.20188

Abstract

Doxorubicin, a well-known chemotherapy drug, is associated with cardiac toxicity primarily due to oxidative stress. This oxidative stress leads to the production of reactive oxygen species and a subsequent decline in antioxidant levels. As doxorubicin induces the formation of free radicals and decreases endogenous antioxidants, it triggers various hematological and biochemical abnormalities. Consequently, the use of antioxidants has been proposed as a strategy to mitigate this damage. This study focuses on the administration of ethanol extract from Andaliman (EAF) fruit, recognized for its rich array of metabolites and antioxidant properties, which may serve as a cardioprotective agent against the adverse effects of doxorubicin. The research involved comprehensive observations, including hematological and clinical chemistry examinations. The findings indicate that EAF demonstrates protective effects by enhancing hematological and clinical chemistry parameters in male Wistar rats subjected to doxorubicin. Notably, these improvements were statistically significant when compared to the control group. Given its promising results, further exploration of EAF as a protective agent for hematological and biochemical health warrants attention and development.
Co-Authors . S, Aminah Ade Sri Rohani Anayanti Arianto Angga Nugraha Sanjaya Anjelisa Z. Hsb, Poppy Arfita Sipahutar Arianto, Anayanti Butar, Ririn Anastasia Butar Candrika, Candrika Darmirani, Yosi Denny Satria, Denny Effendy De Lux Putra, Effendy De Lux Embun Suci Nasution Emil Salim Hafid Syahputra Hakim Bangun* Harahap, Rizki Doli Hartama Herawaty Ginting Iksen, Iksen Julia Reveny Khairunnisa Khairunnisa Khairunnisa Lisda Rimayani Lubis, Arga Lubis, Meiva Amelia Lumbanraja, Linnon Bastian M.S, Wiryanto Masfria Masfria Muhammad Wahyu, Muhammad Nasri Nasri, Nasri Nasution, Azizah Nazliniwaty Nazliniwaty* Nurul Suci Pintauli, Sondang Prayoga, Andre Putri Fiari, Hera Zalia Rexi, Daniel Reza Destri Anggi Simbolon, Rohana Oktofariday Siti Morin Sinaga Sitorus, Panal Sondang Pintauli Sumaiyah Tarigan, Betharina Br Tarigan, Eunike Victorita Tri Susanti Sirait Urip Harahap Vadhila, Mumtaz Wardono, Sri Waruwu, Syukur Berkat Wira Septama, Abdi Wiryanto Wiryanto Wiryanto Yuandani Zumaira