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Journal : INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES

CANTHARANTHUS ROSEUS LEAF EXTRACT ACCELERATES HEALING OF WOUND WISTAR RAT Anom-Dada, I K.; Berata, I K.; Putra-Manuaba, I. B.; Damriyasa, and I M.
INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES Vol 7 No 1 (2013): IJBS Vol.7 No.1 January-June 2013
Publisher : Udayana University

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Abstract

Cantharantus roseus (C. roseus) is a medical plant that has been used to treat various diseases. This study was carried to determine C. roseus leaf extract able to acclerate wound healing in Wistar rat. Full skin-tickness round wounds were created on the back of the rats. Wound healing was evaluated after treated with 15% of a mixture of leaf extract of C. roseus and vaseline. The rats were divided into two groups, each group consist of 16 rats. Wound healing was assesed in five and fifteen days after treatment by measuring wound area, wound closure, and counting the new capillary vessel number (angiogenesis). The result of the study indicated that extract of C. roseus leaf accelerates the wound healing in Wistar rat. Coverage rate of wound is faster on treated group than control group (p<0.05). Wound closure and angiogenesis in early wound healing were higher in treated group than control group (p<0.05). These results suggested that the first phase of wound healing was shortened, and the proliferative and maturation phases were advanced by methanol extract of C. roseus leaf. Therefore, it can be concluded that C. roseus could be potential to help in topical management of wound healing.  
SENSITIVITY AND SPECIFICITY OF ELISA TEST USING 30 KDA RECOMBINANT ANTIGEN TO DETECT Toxoplasma gondii INFECTION IN PIG WITH MICE BIOASSAY AS A GOLD STANDARD Nyoman Adi Suratma1????, I Made Bakta2, I Made Damriyasa3 Adi Suratma, Nyoman; Bakta, I Made; Damriyasa, I Made
INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES Vol. 3, No. 1 Januari 2009
Publisher : Udayana University

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Abstract

Toxoplasmosis is a zoonotic disease caused by the protozoa Toxoplasma gondii.Primary infection in pregnant women can cause abortion, neonatal death or abnormalityof fetus. Accurate diagnosis is needed to prevent infection especially related to thepresence of cyst in the tissuesThe aim of this research was to study sensitivity and specificity of ELISAmethod with 30 kDa protein antigen to detect T.gondii infection in pig with micebioassay as gold standard.. Samples were 171 pigs slaughtered at pig slaughter house inDarmasaba BadungThe result showed that sensitivity of ELISA method was 100% and 90,7% inspecificity.Research about sensitivity using ELISA test to predict cysts presence in tissuewere needed in the future.
Co-Authors Adryani Ris Akira Ito Anak Agung Gde Oka Dharmayudha Anak Agung Komang Suardana Anak Agung Sagung Kendran BERNA NATALIA SILABAN Desak Nyoman Dewi Indira Laksmi Dewa Putu Sahadewa Dharmawan N.S Dina Harumna Endang Wulandari Suryaningtyas Farika E. Y Gede Yudi Suryawan Handayani, Ni Made HERTATI ANRIANI LUBIS I Gede Mahardika I K. Berata I K. K. Agustina I Kadek Saka Wiryana I Kadek Swastika I Ketut Anom Dada I Ketut Berata I Ketut Suada I Made Angga Prayoga I Made Bakta I Made Dwinata I MADE INDRA PERMADI I Made Kardena I Made Merdana I Made Subrata I Nengah Kapti I NYOMAN ADI SURATMA I Nyoman Arsana, I Nyoman I NYOMAN MANTIK ASTAWA I Nyoman Polos I Nyoman Sunita I Nyoman Wijaya Guna I PUTU YOGA LOKANTARA I Wayan Bebas I Wayan Masa Tenaya I Wayan Masa Tenaya, I Wayan Masa I Wayan Wahyudi, I Wayan I. B. Putra-Manuaba Ida Ayu Laksmi Puspita Dewi Ida Ayu Pasti Apsari Ida Bagus Gde Yudha Triguna Ida Bagus Komang Ardana Ida Bagus Made Oka Ida Bagus Ngurah Swacita Ida Bagus Oka Winaya K. K. Agustina Kadek Agus Agra Arnawa Kadek Ayu Dwi Suryastini Kadek Dianiyanti Kadek Karang Agustina Ketut Budiasa Luh Dewi Anggreni MARIANA KRESTY FERDINANDEZ MORI FRISKA TAMBA Muhammad Ulqiya Syukron Munehiro Okamoto N. T. Suryadhi N.S. Dharmawan Ngakan Putu Anom Harjana Ni Ketut Ayu Juliasih Ni Luh Ayu Trisnayanti Ni Luh Gede Merry Cintya Laksmi Ni Luh Gede Sudaryati Ni Made Yunik Novita Dewi Dewi Nyoman Tigeh Suryadi PANDE KETUT YULIARI PRATIWI DEVI GM Putu Nara Kusuma Prasanjaya Putu Suma Githa Sanjaya Putu Sutisna sang gede purnama Sri Hartini STEFAN THEISEN Stelen, I Dewa Ketut Raeyadi Purnama Sudiartawan, I Putu Sumartono - Sumartono . Sumartono s Sumartono s Sumarya, I Made Tjok G. O. Pemayun, Tjok G. O. Tjok Gede Oka Pemayun, Tjok Gede Oka TRI KOMALA SARI Wayan Tunas Artama Wayan Tunas Artama Widayantari, Anak Agung Ayu Sauca Sunia