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All Journal HAYATI Journal of Biosciences Jurnal Pendidikan Biologi Undiksha Biotika: Jurnal Ilmiah Biologi JURNAL TEKNOLOGI LINGKUNGAN Microbiology Indonesia Buletin Plasma Nutfah Biotropika Bioeksperimen: Jurnal Penelitian Biologi BERITA BIOLOGI BIOLINK (Jurnal Biologi Lingkungan, Industri, Kesehatan) JOHME: Journal of Holistic Mathematics Education BIOEDUSCIENCE Jurnal Biologi Tropis Jurnal Kimia Terapan Indonesia Al-Madrasah: Jurnal Ilmiah Pendidikan Madrasah Ibtidaiyah MITRA: Jurnal Pemberdayaan Masyarakat Walisongo Journal of Chemistry Molekul: Jurnal Ilmiah Kimia BAHTERA : Jurnal Pendidikan Bahasa dan Sastra Jurnal Abdi Insani BIO-EDU: Jurnal Pendidikan Biologi Jurnal Ilmiah Biologi UMA (JIBIOMA) Jurnal Pengabdian kepada Masyarakat Nusantara BONAFIDE: Jurnal Teologi dan Pendidikan Kristen Didache: Journal of Christian Education PEADA': Jurnal Pendidikan Kristen Jurnal ComunitA Servizio Lumbung Inovasi: Jurnal Pengabdian Kepada Masyarakat Oryza : Jurnal Pendidikan Biologi Prosiding Konferensi Nasional PKM-CSR JURNAL HUTAN TROPIS Inculco Journal of Christian Education JURNAL BIOLOGI PAPUA Jurnal Teknologi Lingkungan Molekul: Jurnal Ilmiah Kimia Prosiding Seminar Nasional Pengabdian kepada Masyarakat (SINAPMAS) Jurnal Biologi Udayana

WAHYU IRAWATI

Universitas Pelita Harapan

Author-ID : 2562471

Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Terapi Sel Punca sebagai Inovasi dalam Pengobatan Penyakit Autoimun untuk Mempertahankan Sistem Imunitas Tubuh Manusia Elysabeth Simatupang; Pahotkon Purba; Sherina Juliana; Yohana Ayustin; Wahyu Irawati
Jurnal Biologi Papua Vol 14, No 1 (2022)
Publisher : Jurusan Biologi FMIPA Universitas Cenderawasih

Autoimmune is a disease caused by imbalance of immunology and losing tolerance then causes autoimmunity to attack body tissues in organisms. This disease occurs when the self-antigens attached by adaptive immune response. This disease can be treated by stem cell therapy. Stem cell therapy is an assured alternative to autoimmune treatment. Stem cells that can differentiate or can change themselves into various cells according to the environment and function to replace the damaged body cells. This study aims to find out the utility of stem cell therapy as an innovation in the treatment of autoimmune diseases. Literasture review is the method used in this research and focus to discuss: 1) the body's immune system; 2) immune system disorders; 3) autoimmune disease mechanisms; and 4) Stem cell therapy as an alternative to autoimmune treatment. Through this paper, readers will know that there is one technology to use treating autoimmune diseases, stem cell therapy. The mechanism of utilisation of stem cell therapy varies with each type of autoimmune disease, but this therapy can also cause some side effects. Stem cell therapy repairs damaged cells and replaces them with new, more functional ones. Key words: autoimmune disease; stem cell therapy; human body; medication.

Multiresistensi dan Akumulasi Acinetobacter sp. IrC2 terhadap Logam Berat Wahyu Irawati; Aaron Hasthosaputro; Lucia Kusumawati
Jurnal Biologi Papua Vol 12, No 2 (2020)
Publisher : Jurusan Biologi FMIPA Universitas Cenderawasih

The increasing industrial activity in Indonesia, that is not equipped with appropriate waste treatment, has caused an increase of heavy metal contaminants in water bodies. Heavy metals contamination such as copper (Cu), mercury (Hg), cadmium (Cd), and lead (Pb) contamination in water bodies have endangered aquatic life and public health. For this reason, it is urgently important to lower down the concentration of heavy metal pollutants in the water bodies surrounding industrial areas. Compared to chemical remediation, bioremediation of heavy metal by using indigenous bacteria is more effective and economical, since it can be applied in situ directly and be used repeatedly. Acinetobacter sp. IrC2, used in this study, is Indonesian indigenous bacteria isolated from the industrial waste treatment facility in Rungkut, Surabaya. This study aims, firstly, to investigate the heavy metal multiresistance of Acinetobacter sp. IrC2 against mercury, cadmium, and lead. Secondly, this study intends to examine its bioaccumulation capacity for single and heavy metal alloys. The heavy metal multiresistance test was carried out by measuring the minimum heavy metal concentrations that inhibit bacterial growth (Minimum Inhibitory Concentration/MIC). The bioaccumulation capacity was measured using an atomic absorption spectrophotometer (AAS). It is shown that Acinetobacter sp. IrC2 has high multiresistance to mercury, cadmium, and lead with MIC values of 12 mM, 8 mM, and 18 mM, respectively. Furthermore, it is also resistant to heavy metal mixture of 4.5 mM. The mechanism of bacterial resistance in response to heavy metal toxicity, in general, is by accumulating heavy metals in the cells. The highest amount of accumulated heavy metals identified, from bacteria grown in the medium contains a mixture of heavy metals, were 0.023 mg, 0.084 mg, 0.684 mg, and 1.476 mg per gram of cell dry weight for copper, mercury, cadmium and lead respectively. In conclusion, Acinetobacter sp. IrC2 is a promising heavy metal bioremediation agent due to its heavy metal multiresistance and accumulator characteristics. Key words: Acinetobacter sp. IrC2; cadmium; copper; lead; merkuri

Peranan Intervensi Fisioterapi Metode Senam Kegel Untuk Mengatasi Kegagalan Kerja Sel Otot Polos Pada Kelainan Kandung Kemih Inkontinensia Urin Argorby Simanullang; Naomi Dwany; Ruth Y. Purba; Melany Djami; Wahyu Irawati
Jurnal Biologi Papua Vol 13, No 2 (2021)
Publisher : Jurusan Biologi FMIPA Universitas Cenderawasih

Urinary incotinensia is a disease that causes sufferers to experience urine without realizing it or is often referred to as bed-wetting. Urinary incotinence causes sufferers to experience difficulty or sleep disturbances, depression, isolation, lack of confidence, irritability, limiting social activities, and spending a lot of money on medication so that they really need a treatment solution. Urinary incontinence results from weakening of the smooth muscle in the bladder organs. One of the treatments that can be done to overcome urinary incontinence is using physiotherapy, namely by doing Kegel exercises. The purpose of this paper is to determine the role of physiotherapy interventions using Kegel exercises to overcome the failure of smooth muscle cells in urinary incontinence bladder disorders. This literature review will discuss four focus studies, namely: 1) the structure and function of the renal organ system, 2) the structure and working mechanism of smooth muscle cells, 3) cellular studies of urinary incontinence, and 4) treatment of urinary incontinence using physiotherapy interventions. Physiotherapy with Kegel exercises has the benefit of strengthening the work of the bladder sphincter and pelvic floor muscles. The mechanism is by increasing smooth muscle cell metabolism. The metabolic rate of the muscles will increase the strength of the smooth muscle and the nervous system to contract, so that the smooth muscle will get stronger. However, Kegel exercises do not completely cure urinary incontinence and only relieve the symptoms it causes.Key words: Physiotherapy; Urinary incontinence; Smooth muscles; Cells; Kegel exercises.

Bakteri Indigen yang Diisolasi dari Danau Toba: Acinetobacter junii DT2.1 Multiresisten Tembaga, Methylen Blue, dan Basic Fuchine Irawati, Wahyu; Ambarita, Polin P.; Shaday, Vannesa El; Rahmawati, Sintia Y.
Jurnal Biologi Papua Vol 15 No 2 (2023)
Publisher : Jurusan Biologi FMIPA Universitas Cenderawasih

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31957/jbp.2804

Lake Toba is one of the industrial waste disposal sites around the location. Copper and dyes are pollutants that are toxic and harmful to organisms. Bioremediation using indigenous bacteria isolated from polluted sites is a promising solution to overcome environmental pollution. Bacteria that have multi-resistance to copper and dyes are expected to increase the efficiency of industrial waste treatment. This study aims to: 1) isolate and characterize copper-resistant bacteria, 2) determine the level of resistance of bacterial isolates to copper, 3) test the resistance of bacteria to dyes. Physiological characterization of bacterial isolates was carried out by observing colony and cell morphology, also Gram staining. Molecular characterization was carried out by analysis of the 16S rDNA gene. The copper resistance level was tested by determining the Minimum Inhibitory Concentration MIC value. The dye resistance test was carried out by growing bacteria on a medium containing 100 ppm of dye. There were eight isolates of copper-resistant bacteria with MIC values ranging from 3-7 mM CuSO4 with code as DT1.1; DT1.2; DT1.3; DT1.4; DT1.5; DT2.1; DT2.2; and DT3.1. The three highly resistant bacteria were strains DT1.1 and DT1.3 which were identified as Lysinibacillus macroides and strain DT2.1 was identified as Acinetobacter junii with an MIC value of 7mM CuSO4, respectively. The results of the resistance test to dyes showed that only A. junii strain DT2.1 was resistant to 100 ppm Methylene Blue and Basic Fuschine. Key words: indigenous bacteria; Lake Toba; multi-resistence; dye; copper.

Keunikan Struktur Anatomi dan Morfologi Burung Maleo (Macrochepalon maleo) sebagai Fauna Endemik Indonesia dan Upaya Konservasinya Manalu, Damai Y.; Rido, Elisabeth M.T.; Irawati, Wahyu
Jurnal Biologi Papua Vol 15 No 2 (2023)
Publisher : Jurusan Biologi FMIPA Universitas Cenderawasih

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31957/jbp.2980

Maleo bird is one of the unique animals of the aves class which is included in endemic animals in Indonesia. The Maleo bird is almost endangered due to predators and irresponsible behavior of local people. One of the conservation efforts carried out by the government is contained in Law No. 5 of 1990 and Government Regulation No. 7 of 1999 concerning the protection or conservation of Maleo birds. The purpose of this paper is to analyze the morphological and physiological characteristics of the Maleo bird (Macrochepalon maleo), the anatomy of the Maleo bird (Macrochepalon maleo), the relationship of the uniqueness of the behavior of the Maleo bird (Macrochepalon maleo) with the morphology, anatomy, and physiology of the Maleo bird, as well as conservation efforts of the Maleo bird (Macrochepalon maleo). The method used is a literature review by reading various books, journals and papers and other publications in accordance with the research topic. The results of research that have been conducted show that the morphology, anatomy, and physiology of the Maleo bird are closely related to the behavior of the Maleo bird. The Maleo bird uses a crest located on its head to detect heat when digging an egg nest. Maleo bird legs equipped with sharp hooves can make Maleo birds able to survive in coastal forests. Maleo birds are monogamous animals, namely animals that are loyal to their partners. The advice that can be given through this literature review is that the community must have awareness to take care of the Maleo bird as a form of accountability for the mandate given by God to humans. Key words: Aves; endemic; conservation; maleo; morphology

Kidney Stone Treatment Using the Percutaneous Nephrolithotomy Method (PCNL) Novera, Rusliani S.; Angelica, Apriliana; Maharaja, Dwi P.; Situmorang, Stefani; Irawati, Wahyu
Jurnal Biologi Papua Vol 17 No 1 (2025)
Publisher : Jurusan Biologi FMIPA Universitas Cenderawasih

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31957/jbp.4520

Kidney stones are a serious condition that often occurs in the wider community. The presence of this disease is influenced by genetic factors, diet, dehydration, irregular lifestyle, and unhealthy lifestyle. One of the treatments used to treat kidney stones is Percutaneous Nephrolithotomy (PCNL) for kidney stones measuring more than two centimeters. This study aims to find out about kidney stone treatment using the PCNL method. The method used is a literature study by discussing five study focuses, namely (1) healthy kidney structure and its role in maintaining body balance, (2) kidney structural abnormalities and their impact on health, (3) kidney stone treatment methods and their impact on health, (4) PCNL as a modern treatment solution for kidney stone sufferers, and (5) the process of implementing PCNL in kidney stone treatment. It can be concluded that healthy kidneys are vital organs with integrated structures and functions to maintain the physiological balance of the body and play a role in producing the hormones renin, erythropoietin, and calcitriol. Kidney disorders that often appear are kidney stones caused by waste in the blood or crystallized chemicals such as calcium and oxalic acid. Pharmacological therapy is a therapy that is often used to treat kidney stones using medical drugs and also surgery, but this method has side effects due to the drugs given. PCNL is a non-invasive treatment that utilizes sophisticated medical technology to treat kidney stones. PCNL treatment is done by making a small incision in the skin of kidney stone sufferers so that it does not have significant side effects. PCNL has a high success rate for the treatment of kidney stones

Isolation and characterization of nickel, lead, copper, and cadmium-multiresistant bacteria from the Citarum River, West Java Ruga, Deokward F.; Irawati, Wahyu
Jurnal Biologi Papua Vol 18 No 1 (2026)
Publisher : Jurusan Biologi FMIPA Universitas Cenderawasih

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31957/jbp.5286

Industrial activities along the Citarum River, West Java, have resulted in serious heavy metal contamination, causing negative impacts on aquatic ecosystems and human health. Bioremediation using indigenous bacteria with multi-metal resistance offers an efficient and environmentally friendly solution because these bacteria are directly obtained from contaminated environments and are resistant to several heavy metals simultaneously. This study aimed to isolate and characterize indigenous bacteria from the Citarum River that are multiresistant to a mixture of four heavy metals, namely nickel, lead, copper, and cadmium. The bacteria were isolated using the spread plate method on Luria–Bertani Agar supplemented with a mixture of those heavy metals at a concentration of 1 mM. The isolates were purified by the streak plate method and characterized based on colony morphology and cell morphology through Gram staining. The results showed that 24 bacterial isolates were successfully obtained, all of which were able to grow in a 1 mM mixture of nickel, lead, copper, and cadmium. Morphological characterization revealed diverse colonies dominated by yellow, white, and brown pigmentation, with circular shapes and smooth margins. Gram staining showed that all isolates were Gram-negative bacteria. A total of 16 isolates exhibited darker pigmentation, ranging from dark brown to blackish, when cultivated on heavy-metal-containing media. Dark-colored colonies indicate intensive interactions through biosorption and bioprecipitation mechanisms, resulting in the formation of insoluble compounds such as metal sulfides on the cell surface.

Co-Authors . PATRICIA Aaron Hasthosaputro Aazokhi Waruwu ABYATAR HUGO BASKORO Al Khadziq, Muhammad Fuadzy Alvionita Thana Alya Leonita Lamonta Ambarita, Polin P. Ambarita, Polin Parulian Andara Frida Sheilaliany Daely Angelica, Apriliana Anggun Anggun Aninditya Sri Nugraheni Argoby Simanullang Argorby Simanullang Artha, David Dharmawan Ashiong P Munthe Ashiong Parheheon Munthe Ayustin, Yohana Delvia Bellen Mouretta Bermuli, Jessica Elfani Bora, Merliana Ina Cantika Dela Kurnia Zendrato Charles Immanuel Chelvieana A. Christanti Christeven Mevotema Christian, Grace Purnamasari Christian, Salomo Clement Khrisman Laia Clement Khrisman Laia Daely, Andara Frida Sheilaliany Damai Yanti Manalu David L Gultom Debora V. Widyanti Delfania Apang Madao Deokward F. Ruga Desi L. Sihombing Destya Waty Silalahi, Destya Waty Dipakalyano Dipakalyano Dipakalyano, Dipakalyano Djoko Prasetyo Dominica Feni Valentina Dr. Adolf J.N. Parhusip Dwany, Naomi Dwi N. Susilowati Egilia Lucky Elisabeth Tita Ellen Nur Endah Pangesti Elysabeth Simatupang Eunike Bunga Marvella Eunike Bunga Marvella Eunike Bunga Marvella Fernando Christofer Fernando Christofer Fernando Corneles Moniharapon Fiska Ivana Pratami Putri Tokede Floreta D. Icasari Frichilya Intan Lawa Padang Gaol, Riris Lumban Geoffrey Darrien Fideli Georgine Gladis Paula Sulardi Gim Mi Kyong Giri, Mutiara Yaemeliza Venderry Grace Charity Mary Cartir Greisnaningsi Greisnaningsi Harefa, Dellania Yvonne HARI HARTIKO Hasanah, Intan Andriani Hayati, Lutfiah Isfa Helen Melenia Sianipar Herna Siahaan Hernawati Siahaan Hutauruk, Kristian I Made Samudra Imanuel Adhitya Wulanata, Imanuel Adhitya Intan Cidarbulan Matita Iren Asima Situmorang Jennie Agatherania Listira JOEDORO SOEDARSONO Josephine Elsa Diani Putranto Karnelasatri, . Keisha Hillary Pangalila Kosi, Ice Frans Krisdarwindah Mardiana Kristin Armis Pasaribu Laia , Clement Khrisman Laia, Clement Khrisman Laoli, Beta Mualiman Lastiar R. Sitompul Lastiar Roselyna Sitompul, Lastiar Roselyna Legesang, Eddowardho Otniel Lucia Kusumawati Lusiana Haris Maha, Paldevina Br Maharaja, Dwi P. Malau, Robeka Risky Manalu, Damai Y. Manalu, Damai Yanti Marcellie, Jessica Margaretha, Cecilia Marvella, Eunike Bunga Melany Djami Meyners, Geraldy John Mia Parhusip Muhamad Ananda Munthe, Ashiong P. Munthe, Sri Wahyu Ningsih Naomi Dwany Nexson Parhusip, Adolf Jan Nicolas Tunggul Adhigandewa Nida Sopiah Nida Sopiah Nida Sopiah Nommensen Pangihutan Ompusunggu Nommensen Pangihutan Ompusunggu Novera, Rusliani S. Novera, Rusliani Sesy Orah, Eklesia Taysa Pahotkon Purba Pangaribuan, Medeliene Christine Patricia Patricia Pebrianti Pebrianti, Pebrianti Pingkan Imelda Wuisan Polin Parulian Ambarita Ponagadi, Merry Adisty Prasetyo, Djoko Purba, Friska Juliana Purwanti, Ester Ayu Sri PutrI, Nadya Aurelia Ratna Rahmawati, Sintia Y. Rahul Simon Situmeang Rani Nurlina Tifen Raudhatunnur Reinhard Pinontoan Resky Megawati Tammu Resti Nopriyanti Rido, Elisabeth M.T. Rimpan, Takashi Reymond Rosiva Betaria Purba Ruben Patrick Adhiwijaya Ruga, Deokward F. Ruth Y. Purba Sabar Manampin Giawa Salomo Christian Selvi Esther Suwu, Selvi Esther Shaday, Vannesa El Sherina Juliana Sherina Juliana Siane Indriani, Siane Siane Indriyani Sianturi, Golda Santiur Silaban, Grace Niche Agnesa Silalahi, Ramses Silvana Putri Tarigan Simamora, Tanti Marsanda Sindy Friska Siringo-ringo, Sisilya Situmorang, Stefani Situmorang, Widya Srigika Natalia Boru Ginting Stephanus Jordan Jans Steven Anggawinata Sudarsono Siburian Sugata, Marcelia Suhartono, Andreas Valiant Sukri, Urbanus Susi Sulistia Susi Sulistia, Susi Tabitha Grace Larasati Tahya, Candra Tahya, Candra J. Tahya, Candra Yulius Tammu, Reisky Megawati Thesalonika Liony Pangemanan Tinambunan , Christine Febriandini Torreno, Jovan Nathanael Tri P. Priyatno Triwibowo Yuwono Valiant, Andreas Vania Austine Callista Timotius Vannesa El Shaday Ruth Advenita Viona Heryani Arla Waruwu, A'azokhi Wuisan, Pingkan Imelda Xaveria, Jessica Yadi Suryadi Yantra Wijaya YENNY SORAYA Yesica C. Rhenata Yohana Ayustin Yohanes Edi Gunanto Yolanda, Shelomita Feby Yovanka P.P Tumakaka Zebua, Satria Putri Aryani Zega, Yeni Angelina

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