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All Journal Jurnal Teknologi Dan Industri Pangan JURNAL GIZI INDONESIA Jurnal Ilmu keperawatan Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Jurnal Kesehatan Reproduksi UNEJ e-Proceeding Sari Pediatri Paediatrica Indonesiana Jurnal Gizi dan Dietetik Indonesia (Indonesian Journal of Nutrition and Dietetics) Jurnal Gizi Klinik Indonesia Jurnal Keperawatan Respati Yogyakarta Basic and Applied Nursing Research Journal Berita Kedokteran Masyarakat Jurnal Farmasi Indonesia Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)
Madarina Julia
Universitas Gadjah Mada
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Neuroscience Nursing Public Health Other

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Journal : UNEJ e-Proceeding

 1 
LOCAL WISDOM OF JEMBER COMMUNITY IN REDUCING CYANOGENIC LEVELS TO LOWER URINE THIOCYANATE LEVELS Farida Wahyu Ningtyias; Ahmad Husain Asdie; Madarina Julia; Yayi Suryo Prabandari
UNEJ e-Proceeding Proceeding of 1st International Conference on Medicine and Health Sciences (ICMHS)
Publisher : UPT Penerbitan Universitas Jember

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Abstract

Disorders caused by iodine deficiency remains aglobal health problem in the world with a prevalenceof 30.6% in 2007 (De Benoist et al., 2003; De Benoistet al., 2008). The causing factors are not only limitedto iodine deficiency. Instead, other factors of IDD aregoitrogenic substances; one of them is thiocyanateresulted from cyanide detoxification. The workmechanism of thiocyanate disrupts thyroid functionby inhibiting the uptake of the iodine and interfereswith the thyroid peroxidase (TPO) activities (Gaitan,1990; Taurog, 1970; Van Etten, 1969; Stoewsand,1995; Virion et al., 1980 cit Chandra & Ray, 2001;Chandra et al., 2004; Delange, 2000; Erdogan, 2003;Gibbs, 2006; Sinebeeh, 2007; Semba & Delange,2008). In addition, small amount of cyanide is alwaysavailable in many kinds of plants commonlyconsumed by community. Goitrogenik source foodsare easily accessible by the community because theprices are cheap or they can be self-planted (Nio,1989; Chandra et al., 2004).Some studies mention that most of the goitrogenicsubstances do not cause clinical effects except theyare going along with iodine deficiency. Therefore,the consumption of goitrogenic substances becomesetiologic agent in an endemic area (Zimmermann etal., 2008). Jember is one of regencies in East Javawhich experiences an increase in TGR from 21.94%in 2003 to 23.57% in 2007. Most of its districts areincluded in the category of endemic goiter area(Jember regency Health Department, 2007). Theresults of previous studies made by the researchersshow that goitrogenic substance as a causativefactor of IDD in Jember, through one of theindicators of urinary iodine levels, is included in thecategory of normal and tend to be high. In addition,urinary thiocyanate levels goiter group are higherthan those in non-goiter group (Ningtyias, 2006;Ningtyias et al., 2007; Ningtyias et al., 2008).Consumption pattern of goitrogenic source food inJember of at least 3-5 times per week with anaverage consumption of 505 μg per day is a riskfactor of IDD in Jember (Megawati, 2007; Ningtyiaset al., 2008). The existence of these substances willdisrupt the process of the formation of thyroidhormones; therefore, it needs to be eliminated, orthe levels are reduced, so that the food ingredientscontaining goitrogenic substances are safe forconsumption. This study used local wisdom to solveproblems of nutrition, that is, one of the habits ofpeople in Jember to boil vegetables for freshvegetables for overcoming nutritional problem ofIDD because the boiling process can reducecyanogenic levels up to 93% (Murdiana, 2001). Bythe decrease in cyanogenic levels, it is expected thatgoitrogenic substance intake into the body willdecrease indicated by the decreasing biomarkers ofgoitrogenic substance of urinary thiocyanate levels.
Co-Authors A.A. Ketut Agung Cahyawan W Achmad Surjono Adhila Fayasari Agustini Utari Ahmad Husain Asdie Ahmad Husain Asdie Ahmad Husain Asdie Ahmad Husain Asdie Almira Sitasari Aman B Pulungan Andi Imam Arundhana Ari Tri Astuti, Ari Tri Arief Priambodo Astuti, Lucia Mawarti Dwi Attika A. Andarie Basuki, Siswanto Betaditya, Dika Burhan, Fatimah Zahra Cerdasari, Carissa Dewi Astiti Diadra Annisa Dio Biade Djaswadi Dasuki Djauhar Ismail Ekawaty L. Haksari Emy Huriyati Endang Baliarti Endy P. Prawirohartono Endy Paryanto Prawirohartono, Endy Paryanto Eni Harmayani Esti Nurwanti Farida Wahyu Ningtyas Farida Wahyu Ningtyas Farida Wahyu Ningtyias, Farida Wahyu Fitri Haryanti Frida Soesanti Gunawan, I Made Alit H. A. Delemarre-van de Waal HA Delemarrevan de Waal Hamam Hadi Hamam Hadi Handayani Handayani Harry Freitag Luglio Muhammad Helmyati, Siti Hendratini, Julita Hizni, Alina I Made Alit Gunawan I Wayan Bikin ika agustina Indria Laksmi Gamayanti Indria Laksmi Gamayanti Irma Yunawati Joko Susilo Jufrrie, Muhammad Junaidi Junaidi Jurianto Gambir Kandarina, Bernadette Josephine Istiti Khaerul Anwar Kunayarti, Wahyuni Kurnia Febriana Laksono Trisnantoro Lamana, Aspia Legawati Legawati, Legawati Lely Lusmilasari, Lely Lisma Evareny, Mohammad Hakimi, Retna Siwi Padmawati M M van Weissenburch M. M. van Weissenbruch Mohammad Hakimi Muchtar, Mohammad Mursyid, Abidillah Neti Nurani Niken Pritayati Nina Lestari Nisa, Fatma Zuhrotun Noormanto Noormanto, Noormanto Nugroho, Akmad Kharis Nur Afia Amin Nurliyani Nurul Hadi, Nurul Nuryanti Nuryanti Pangesti, Neni Paulinus Deny Krisnanto Purnama, Ni Luh Agustini Putra, Irwansyah R. Dwi Budiningsari Rahayu, Endah Sri Rahmawati, Rahmawati Ramadhaniah, Ramadhaniah Ramli, Nurlaili Retno Sutomo Rianti Puji Lestari Rina Susilowati Riris Andono Ahmad Roni Naning Ronny Martien Ruqoyatul Himah S. Yudha Patria Santi Gunarwati Setya Wandita Shelly Puspa Anggraini Shinta Prawitasari Shoim, Mohammad Siti Nurfadilah H Slamet Rohaedi, Slamet Soeroyo Machfudz, Soeroyo Soi, Beatrix Solly Aryza Sri Mulyati Sri Sugiharti Sri Wahyuni Subardjo, Yovita Puri Sulistyaningrum, Elisa Sunartini Sunartini, Sunartini Susetyowati Tarigan, Noviani Titih Huriah Titih Huriah Toto Sudargo Tunjung Wibowo Tuti Nuraini Tuti Nuraini Winda Irwanti, Winda Winda Nurmayani M Yayah Lakoro Yayi Suryo Prabandari Zulfayeni, Zulfayeni