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All Journal Jurnal MIPA PHARMACON Jurnal Dinamika Pengabdian (JDP) Universa Medicina Jurnal Farmasi Medica (Pharmacy Medical Journal) PMJ Jurnal Biomedika dan Kesehatan The Studies of Social Sciences Vivabio : Jurnal Pengabdian Multidisiplin Jurnal Kesehatan Tambusai Jurnal Lentera Farma
Hosea Jaya Edy
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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PENGARUH MODAL SOSIAL DAN BUDAYA ORGANISASI TERHADAP KINERJA TENAGA MEDIS DI RSUD KABUPATEN KEPULAUAN TALAUD Edy, Yosua Jaya; Maupa, Haris; Edy, Hosea Jaya
PHARMACON Vol 2, No 3 (2013): pharmacon
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.2.2013.2392

Abstract

ABSTRACTThis study aims to analyze the direct effect of social capital factors and organizational cultureon the performance of medical personnel in hospitals Talaud Islands. The population in thisstudy is the Civil Servants (PNS) in Talaud Islands who served in hospitals Talaud Islands.Sampling technique in this study is proportional sampling with a sample size of 100 people.In the data analysis using Structural Equation Modelling (SEM), using AMOS program(Analysis of Moment Structure) 20. Structural Equation Modeling (SEM) is a multivariateanalysis technique that was developed to cover the limitations that are owned by the previousanalytical models that have been widely used in statistical research. Stuctural equation model(SEM) can be seen as a combination of factor analysis, path analysis, and regression. Theresults indicate that (1) Social Capital and significant positive effect on the performance ofmedical personnel in hospitals Talaud Islands (2) Organizational culture positive andsignificant impact on the performance of medical personnel in hospitals Talaud Islands.Keywords : Social capital, Organization Culture, Performance
IDENTIFIKASI FITOKIMIA DAN UJI DAYA HAMBAT DARI EKSTRAK ETANOL TANGKAI BUAH PINANG YAKI (ARECA VESTIARIA GISEKE) TERHADAP BAKTERI STAPHYLOCOCCUS AUREUS, ESCHERICHIA COLI, DAN PSEUDOMONAS AERUGINOSA Redwik, Danni Umbu Wira; Simbala, Herny; Edy, Hosea Jaya
PHARMACON Vol 8, No 4 (2019)
Publisher : PHARMACON

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

ABSTRACT Areca nut (Areca vestiaria Giseke), which is a kind of wild palm, is a multi-functional plant. The North Sulawesi people empirically use this plant to cure various diseases. This study aims to determine the phytochemical content and antibacterial activity of ethanol extracts of areca nut against the inhibitory growth of Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa using 5 concentrations namely 1%, 2%, 3%, 4% and 5%. Extraction was done by maceration using 96% of ethanol. Antibacterial activity testing was using paper disc diffusion method (Kirby and Bauer diffusion). The results of this study indicate that the ethanol extracts of areca nut stem contains flavonoids, saponins, triterpenoids that have the potential to be antibacterial and has antibacterial strength against Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa, at concentrations of 4% and 5%, which are concentrations which are included in the group that categorize as strong to inhibit the bacteria E. coli and P. aeruginosa, while the extract concentration of 2%, 3%, 4%, and 5% which are included in the group that categorize as strong to inhibit the S. aureus bacteria. Keywords: Agar diffusion method, Antibacterial, Areca nut, Phytochemical. ABSTRAK Pinang Yaki (Areca vestiaria Giseke) yang merupakan sejenis palem liar, merupakan tanaman yang multi fungsi. Masyarakat Sulawesi Utara secara empiris menggunakan tanaman ini untuk menyembuhkan berbagai macam penyakit.. Penelitian ini bertujuan untuk mengetahui kandungan fitokimia dan aktivitas antibakteri dari ekstrak etanol tangkai buah pinang yaki terhadap daya hambat pertumbuhan bakteri Escherichia coli, Staphylococcus aureus, dan Pseudomonas aeruginosa menggunakan 5 konsentrasi yakni 1%, 2%, 3%, 4%, dan 5%. Ekstraksi dilakukan dengan cara maserasi menggunakan etanol 96%. Pengujian aktivitas antibakteri menggunakan metode difusi dengan cakram kertas (difusi Kirby dan Bauer). Hasil penelitian ini menunjukkan bahwa ekstrak etanol tangkai buah Pinang Yaki memiliki kandungan flavonoid, saponin, triterpenoid yang berpotensi sebagai antibakteri dan memiliki kekuatan antibakteri terhadap Escherichia coli, Staphylococcus aureus, dan Pseudomonas aeruginosa, pada konsentrasi 4% dan 5% merupakan konsentrasi yang termasuk dalam golongan kuat untuk menghambat bakteri E. coli dan P. aeruginosa, sedangkan pada konsentrasi ekstrak 2%, 3%, 4%, dan 5% termasuk dalam golongan kuat menghambat bakteri S. aureus. Kata kunci: Pinang Yaki, Fitokimia, Antibakteri,metode difusi agar
FORMULASI KRIM TABIR SURYA EKSTRAK KULIT NANAS (ANANAS COMOSUS L MERR) DAN UJI IN VITRO NILAI SUN PROTECTING FACTOR (SPF) Damogalad, Viondy; Edy, Hosea Jaya; Supriati, Hamidah Sri
PHARMACON Vol 2, No 2 (2013): pharmacon
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.2.2013.1577

Abstract

This research aims to determine the value of sun protecting factor (SPF) of pineapple skinextracts (Ananas comosus L Merr) in the form of cream with variant concentration of 2%,4% and 8%. The pineapple skin contains flavonoids and tannins substances that can give theeffect as a sunscreen. The formulation of pineapple skin extract cream using the phase of oilin water. The ingredients that was use in the cream formulation are stearic acid, liquidparaffin cera alba, cetyl alcohol, stearyl alcohol, propylene glycol, triethanolamine, distilledwater and nipagin. Cream of pineapple skin extract then giving a variety of specified qualitytesting and SPF value. Each concentration cream diluted using 96% ethanol. Creams that hasbeen diluted read it’s absorbance value at UV-Vis Spectrophotometer instrument thencalculated the SPF values. The results showed that the cream of pineapple skin extract hasmet the requirements after conducting various quality of cream tests and the SPF value ofeach cream concentrations are very low. It’s been Concluded that the concentration ofpineapple skin extract cream 2% has shown a very small SPF value and increasing theconcentration of 4% and 8% demonstrate higher SPF values but still does not meet thestandards as a good sunscreen cream.Keywords : cream, extract, pineapple skin, sunscreen, sun protecting factor
Formulasi Salep Ekstrak Etanol Daun Tapak Kuda (Ipomoea pes-caprae) Dan Uji Efektivitasnya Terhadap Luka Terbuka Pada Punggung Kelinci Muthalib, Eka Mulya; Fatimawali, Fatimawali; Edy, Hosea Jaya
PHARMACON Vol 2, No 3 (2013): pharmacon
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.2.2013.2384

Abstract

ABSTRACTPalm horse weevil contains medicinal properties that are useful in the process of woundhealing. The purpose of this study is to to examine formulate an ointment of palm horse(Ipomoea pes-caprae (L) Sweet) weevil extract and to test the ointment to heal open woundon the skin of rabbits. This study is experimental descriptive in the laboratory. Palm horseweevil extracts used in the manufactured of ointment formulation 10%, 15 % and 20 %. Theresults showed that the palm horse weevil formulation meets the ointment test requirementaccording, making ointment formulation using cassava tuber extract used as 5 rabbits.Divided into 5 treatment gropus, namely, test the ointment treatment group, negative controlgroup (basic ointment) and positive control group (chloramphenicol ointment). Observed thehealing effects for 7 days. The results showed that from day-1 to day-7 observations burnssuffered diminution in diameter. It was concluded that concentration of 10 % cassava extractontment has healing effect and increasing the concentration of 15 % and 20 % containedshowed more effective and speed up the healing process.Keywords : Extract leaf palm horse , ointment, wound healing, rabbit.
FORMULASI KRIM EKSTRAK ETANOL DAUN LAMUN (Syringodium isoetifolium) Juwita, Anisa Puspa; Yamlean, Paulina V.Y; Edy, Hosea Jaya
PHARMACON Vol 2, No 2 (2013): pharmacon
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.2.2013.1414

Abstract

Seagrass (Syringodium isoetifolium) is a plant that lives submerged at sea, this floweringplant, leaves, and stems that are plugged into a powerful in water. The chemical content ofthe leaves of the Seagrass is a flavonoid, phenol, hydroquinone, and antioxidants.This studyaims to determine the quality of the cream of seagrass leaf extracts using a concentration of5%, 10%, 20% dan 40%. on organoleptic testing conducted cream, homogeneity test, testdispersive power, pH and absorbance test. results obtained in the organoleptic seen from thecolor green, semi-solid dosage forms and distinctive smell seagrass cream. homogeneity test.homogeneity test cream seagrass leaf extract with a concentration of 5% 10% 20% and 40%did not experience any clumping or phase separation dispersive power test creams rangedfrom 2.5 cm - 3.5 cm. pH ranged from 4.93 - 5.96 and test absorption ranged from 3.7 ml - 5ml. seagrass leaf extract cream with type W/O creams that meet the test of homogeneity testquality, dispersive power test, test and test pH absorptionKeyword : Syringodium isoetifolium, Seagrass Leaves, Cream W/O
EFEK ANTIBAKTERI SALEP EKSTRAK RIMPANG LENGKUAS PUTIH (Alpinia galangal [L] Swartz) PADA KULIT PUNGGUNG KELINCI YANG DIBUAT INFEKSI Staphylococcus aureus Tandy, Debora; Edy, Hosea Jaya; Supriati, Hamidah Sri
PHARMACON Vol 1, No 2 (2012)
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.1.2012.509

Abstract

The aim of these research were to study antibacterial effect, effective concentration, and theeffect of concentration alteration of white galangal rhizome extract ointmentto heal rabbitsback skininfected with Staphylococcus aureus. Extraction was done by maceration usingethanol 96% as solvent. Observation of healing time was done by observing infectionhealingtime on rabbits back skin after anointment treatment, which based onthe disappearance oferythema and pus. The result shows that 10% of white galangal rhizome extract ointmenteffective to heal the infection of Staphylococcus aureus. It shown by its short healing timecompared with concentration 3% and 5%. One way ANOVA result shows that there was asignificant effect between concentrations 3%, 5%,and 10%. (Fcalculation 27,30>Ftable 3,48),it meant that high concentration resultingshorter healing time.Keywords: antibacterial effect. Alpinia galangal L., Staphylococcus aureus, rabbit backskin
Edukasi Penggunaan Antibiotika, Obat Keras, dan Over The Counter Medicine sebagai Upaya Pengendalian Resistensi dan Misused Drug di Kolom VIII GMIM Jemaat Victory Minanga Indah Kota Manado Siampa, Jainer P; Edy, Hosea Jaya
VIVABIO: Jurnal Pengabdian Multidisiplin Vol 1, No 2 (2019): VIVABIO: Jurnal Pengabdian Multidisiplin
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/vivabio.1.2.2019.24932

Abstract

Obat adalah zat kimia yang bersifat racun, namum dalam jumlah tertentu dapat memberikan efek yang baik bagi tubuh. Efek preventif dan kuratif yang bisa dihasilkan dengan mengonsumsi obat, membuat masyarakat sangat sering menggunakan obat untuk pengobatan sendiri (swamedikasi). Kenyataan yang ditemukan adalah masyarakat tidak memiliki informasi yang cukup tentang obat untuk menjamin keamanan dan keselamatan mereka. Hal ini pun terjadi pada masyarakat yang termasuk dalam Kolom VIII GMIM Victory Minanga Indah Kelurahan Malalayang II Kecamatan Malalayang Kota Manado Sulawesi utara sehingga perlu dilakukan edukasi. Kegiatan ini bertujuan untuk memberikan edukasi yang tepat tentang obat keras, antibiotika, obat bebas, dan swamedikasi sehingga dapat mengendalikan resistensi dan penyalahgunaan obat. Pemahaman yang benar tentang obat adalah racun akan membuat masyarakat lebih berhati-hati menggunakannya. Metode pelaksanaan adalah penyuluhan, studi kasus, dan diskusi. Capaian dari kegiatan ini adalah peningkatan pemahaman anggota masyarakat yang terukur dari hasil studi kasus dan diskusi. Masyarakat dapat dengan benar memecahkan kasus yang ada sehingga dapat disimpulkan bahwa kegiatan edukasi berhasil dengan baik dan  masyarakat dapat menyampaikan informasi penting kepada keluarga dan masyarakat sekitar.
PKM di Perum Puri Kelapa Gading Paniki Atas, Talawaan, Minahasa Utara, Sulawesi Utara Tentang Edukasi Mencegah Penyebaran Covid-19 Edy, Hosea Jaya; Jayanto, Imam
VIVABIO: Jurnal Pengabdian Multidisiplin Vol 2, No 2 (2020): VIVABIO:Jurnal Pengabdian Multidisiplin
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/vivabio.2.2.2020.30571

Abstract

Covid-19 merupakan penyakit menular yang bermula dari Wuhan, China. Sekitar lebih dari 200 negara di dunia terjangkit virus covid-19 dan banyak menimbulkan korban jiwa dalam waktu yang sangat cepat. Pemerintah melakukan pembatasan kegiatan masyarakat sebagai upaya memutus mata rantai penyebaran virus covid-19. Pencegahan penyebaran penyakit menular tersebut harus segera dilakukan dengan tepat. Metode yang dilakukan adalah Kampanye Informasi Edukasi (KIE) kepada warga agar terhindar dari penularan Covid-19. Edukasi yang diberikan adalah himbauan untuk mengenakan masker, mencuci tangan dan menjaga jarak sosial. Hasil dari KIE dalam rangka pencegahan Covid-19 di Perum Puri Kelapa Gading adalah peningkatan kesadaran warga untuk mengenakan masker sebesar 68% untuk warga yang mengendarai mobil, 40% untuk warga yang mengendarai motor dan meningkat 150% bagi warga yang berjalan kaki. Edukasi dan bantuan yang diberikan mampu memberikan solusi bagi warga Puri Kelapa Gading untuk menjaga diri dari paparan Covid-19.
Uji Antibakteri Sediaan Masker Peel Off Ekstrak Etanol Daun Alpukat (Persea ameicana Mill.) terhadap Bakteri Staphylococcus epidermidis sebagai Antijerawat Puluh, Esterlina Aldora; Edy, Hosea Jaya; Siampa, Jainer Pasca
Jurnal MIPA Vol 8, No 3 (2019)
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jmuo.8.3.2019.25773

Abstract

Daun Alpukat memiliki kandungan antara lain saponin, alkaloid, flavonoid, polifenol, quersetin yang bersifat sebagai antibakteri.  Penelitian ini bertujuan untuk mendapatkan konsentrasi terbaik dari ekstrak etanol daun alpukat (Persea americana Mill.) yang diformulasikan sebagai sediaan masker gel peel off berdasarkan uji aktivitas antibakteri terhadap bakteri Staphylococcus epidermidis. Penelitian ini menggunakan metode ekperimental laboratorium. Formula sediaan masker gel peel off ekstrak daun Alpukat dibuat dengan variasi konsentrasi 0.1%; 0.15%; 0.2%; 0.25% dan 0.3%. Ekstrak tanaman daun alpukat diperoleh dengan cara maserasi menggunakan pelarut etanol 96%. Pengujian antibakteri dengan metode sumuran diameter zona hambat yang paling besar yaitu pada konsentrasi 0,3% dengan diameter zona hambat 3 mm ± 0,32 dan kemampuan daya hambat dikategorikan lemah. Dapat disimpulkan bahwa konsentrasi terbaik dari ekstrak etanol daun Alpukat (Persea americana Mill.) yang diformulasikan sebagai sediaan masker gel peel off yaitu pada konsentrasi 0.3% dan dikategorikan kemampuan daya hambat lemahAvocado leaves contains saponins, alkaloids, flavonoids, polyphenols, quercetin which are as antibacterial properties. This study aims to obtain the best concentration of ethanol extract of avocado leaves (Persea americana Mill.) which is formulated as a gel peel off mask preparation based on antibacterial activity test against Staphylococcus epidermidis bacteria. This study uses a laboratory experimental method. Avocado leaf extract peel off mask gel formula is made with a concentration variation of 0.1%; 0.15%; 0.2%; 0.25% and 0.3%. Avocado leaf extract is obtained by maceration using 96% ethanol solvent. Antibacterial testing with the largest inhibition zone diameter wells method is at a concentration of 0.3% with a diameter of inhibition zone 3 mm ± 0.32 and the ability of inhibition is categorized as weak. It can be concluded that the best concentration of ethanol extract of avocado leaves (Persea americana Mill.) Which is formulated as a gel peel off mask preparation is at a concentration of 0.3% and categorized as weak inhibitory ability
Uji Efektivitas Antibakteri Sediaan Krim Ekstrak Etanol Daun Kaliandra (Calliandra surinamensis) Terhadap Bakteri Staphylococcus aureus Somba, Gichella C.J; Edy, Hosea Jaya; Siampa, Jainer Pasca
Jurnal MIPA Vol 8, No 3 (2019)
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jmuo.8.3.2019.25776

Abstract

Daun Kaliandra (Calliandra surinamensis) mengandung senyawa flavonoid, saponin dan tannin yang mampu menghambat pertumbuhan bakteri. Penelitian ini bertujuan untuk memformulasi dan mengetahui efektivitas antibakteri sediaan krim ekstrak etanol daun Kaliandra terhadap bakteri Staphylococcus aureus. Penelitian ini menggunakan metode eksperimental laboratorium. Formula sediaan krim dibuat dengan variasi konsentrasi ekstrak etanol daun Kaliandra 2%, 3%, 4%, 5%, 6%. Ekstrak daun Kaliandra diperoleh dengan cara maserasi menggunakan pelarut etanol 96%. Penelitian uji antibakteri sediaan krim esktrak etanol daun Kaliandra menggunakan metode sumuran pada bakteri Staphylococcus aures menghasilkan daya hambat yang terbesar 5,09±0,88 mm pada konsentrasi 6%. Dapat disimpulkan bahwa sediaan krim ekstrak etanol daun Kaliandra memiliki efektivitas  antibakteri yang sedangKaliandra leaf (Calliandra surinamensis) contains flavonoid compounds, saponins and tannins that can inhibit bacterial growth. The aim of this study was to formulate and investigate the antibacterial effectiveness of Kaliandra leaf ethanol extract cream against Staphylococcus aureus. This research uses laboratory experimental methods. Cream preparation formula is made with variations in the concentration of ethanol extract of Kaliandra leaves 2%, 3%, 4%, 5%, 6%. Kaliandra leaf extract was obtained by maceration using 96% ethanol solvent. The antibacterial test study of ethanol extract of Kaliandra leaf extract using the method of Staphylococcus aures produced the greatest inhibition of 5.09 ± 0.88 mm at a concentration of 6%. It can be concluded that the ethanol extract of Kaliandra leaf cream has moderate antibacterial effectivenessDaun Kaliandra (Calliandra surinamensis) mengandung senyawa flavonoid, saponin dan tannin yang mampu menghambat pertumbuhan bakteri. Penelitian ini bertujuan untuk memformulasi dan mengetahui efektivitas antibakteri sediaan krim ekstrak etanol daun Kaliandra terhadap bakteri Staphylococcus aureus. Penelitian ini menggunakan metode eksperimental laboratorium. Formula sediaan krim dibuat dengan variasi konsentrasi ekstrak etanol daun Kaliandra 2%, 3%, 4%, 5%, 6%. Ekstrak daun Kaliandra diperoleh dengan cara maserasi menggunakan pelarut etanol 96%. Penelitian uji antibakteri sediaan krim esktrak etanol daun Kaliandra menggunakan metode sumuran pada bakteri Staphylococcus aures menghasilkan daya hambat yang terbesar 5,09±0,88 mm pada konsentrasi 6%. Dapat disimpulkan bahwa sediaan krim ekstrak etanol daun Kaliandra memiliki efektivitas  antibakteri yang sedang
Co-Authors Abdullah, Surya Sumantri Ade Novia Mokodompit Adithya Yudistira Agnes S. G. Sahuleka Anisa Puspa Juwita Apitalau, Etserlisa A. Arsianita Ester Wawo Bidulang, Crunny Bidhya Ciptanti Putri Prakarsa Citra Tompunu David Tjahyadi Debora Tandy Djafar, Fadillah Djebli, Noureddine Eka Mulya Muthalib Ekadelania Buyung Elly Suoth Falles Raintung The Fathoni, Kristiani W. S. W. Fatimawali . Gayatri Citraningtyas Gratia, Berta Hairunisa, Nany Hamidah Sri Supriati Hardy Senjaya Haris Maupa Herny E.I. Simbala Hisan, Annisa Khoirotun Husnun Amalia I Made Putra Suwertayasa Inriani MarlinMareyke Rumayar Jainer Pasca Siampa Jayanto, Imam Jonathan Christofel Rumangkang Jovie M. Dumanauw2 Kalalo, Marko Jeremia Karlah L. R. Mansauda Korengkeng, Nathania Anabel Lebang, Julianri S. Legi, Angelika Pretty Lestari, Monica Dewi M. Agung Pratama Suharto Mallaka, Indriyani MANGUNE, GLORYA DORCHICYLHIA Marko Jeremia Kalalo Meilani Jayanti Missyeling Fransisca Saerang ML Edy Parwanto Mumu, Britney Stevani Nathania Anabel Korengkeng Novel Kojong Oladimeji, Ashaolu Victoria Parwanto, Edy Paulina yamlean Pongsapan, Abdul David Prayoga, Deshanda Kurniawan Puluh, Esterlina Aldora Purnomo, Novia Hanna Rajab, Mustika Nur Rambi, Salfa Efata Glory Redwik, Danni Umbu Wira Romario Aldi Rompas Santika Angela Van Gobel Sarwan, Sarwan Sergio Christiano Mandagi JR Siampa, Jainer P Siampa, Jainer Pasca Somba, Gichella C.J Sri Murti Sari Syamsuddin Sri Sudewi, Sri Sukartiningsih, Yulita Ni Nyoman Surya Sumantri Abdullah Tiara Mappa Tondolambung, Axcel H. Tunas, Theresia H. Valencia Lumantow Viondy Damogalad Vyta N Sari Sinrang Weny Wiyono Widdhi Bodhi Yosua Jaya Edy