Claim Missing Document
Check
Articles

Found 38 Documents
Search

Antioxidant Activity of Edible Bird’s Nest (Aerodramus fuciphagus) from Central Borneo, Indonesia Sandi, Dita Ayulia Dwi; Susiani, Eka Fitri; Rahmatullah, Satrio Wibowo; Adnyana, I Ketut; Wikaningtyas, Pratiwi
Borneo Journal of Pharmacy Vol. 8 No. 1 (2025): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v8i1.6595

Abstract

Edible bird's nests (EBNs) from Aerodramus fuciphagus have been traditionally used in Asia for their various health benefits, including antioxidant properties. Previous studies have reported antioxidant activity in EBN water extracts using methods like ABTS and ORAC. However, the antioxidant activity can vary significantly depending on factors such as the source of EBN, extraction methods, and the specific assay used. This study aimed to comprehensively evaluate the antioxidant potential of EBN water extract using a range of in vitro assays. The antioxidant activity was assessed using four different methods: 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, nitric oxide (NO) radical scavenging, ferric reducing antioxidant power (FRAP), and cupric reducing antioxidant capacity (CUPRAC). Results demonstrated that the EBN water extract exhibited moderate NO radical scavenging activity with an IC50 value of 116.86 μg/mL. While weak activity was observed in the DPPH assay, the FRAP and CUPRAC assays showed promising antioxidant potential with an ascorbic acid equivalent (AAE) of 4.567±0.30 and 3.487±0.095 μg AAE/mL, respectively. These findings suggest that the antioxidant activity of EBN water extract may be primarily attributed to its protein content. However, further investigations are warranted to elucidate the specific mechanisms of action and isolate the bioactive compounds responsible for the observed antioxidant effects. These findings have implications for the development of EBN-based functional foods, nutraceuticals, and cosmeceuticals with enhanced antioxidant properties.
Kacip Fatimah (Labisia pumila) as Natural Sunscreen: Analysis of Flavonoid Content and Ultraviolet Protection Ability Rahmatullah, Satrio Wibowo; Rizki, Muhammad Ikhwan; Sari, Anna Khumaira; Sari, Fitri Novita; Fadlilaturrahmah, Fadlilaturrahmah; Junjung Buih, Putri Helena
Tropical Health and Medical Research Vol. 7 No. 1 (2025): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v7i1.132

Abstract

The cause of melanoma cancer is exposure to high-intensity ultraviolet rays from sunlight. Kacip Fatimah (Labisia pumila) utilizes the people of the interior of Kalimantan to protect their skin from sunlight by attaching leaves to the face or skin. Kacip Fatimah (Labisia pumila) contains flavonoid compounds, which are thought to impact these various properties. This study aimed to determine the ultraviolet protection ability and total flavonoid levels of Kacip Fatimah (Labisia pumila) leaves. Kacip Fatimah (Labisia pumila) leaves originating from Central Kalimantan were cleaned, dried in an oven, ground, and then extracted with air solvents, 70% ethanol, and 96% ethanol. Flavonoid identification was carried out with specific reagents, and total flavonoid levels were determined by colorimetric method using quercetin as a comparison. The ultraviolet protection ability of Kacip Fatimah (Labisia pumila) leaf extract was measured using a UV-Vis Spectrophotometer with the Sun Protection Factor parameter. The results showed the presence of flavonoids in the third extract. The total flavonoid content of air extract, ethanol 70%, and ethanol 96% from Kacip Fatimah (Labisia pumila) leaves were obtained respectively at 1.69%, 2.15%, and 2.38%. The most extracted flavonoids were in ethanol 96%solvent. The ultraviolet protection ability at a concentration of 100 - 500 ppm from air extract was in the range of 2.80 - 7.99, in ethanol 70% extract in the range of 5.69 - 38.39, while in ethanol 96% extract in the range of 8.76 - 49.07. The highest ultraviolet protection was in 96% ethanol extract from Kacip Fatimah (Labisia pumila) leaves. The results showed that Kacip Fatimah (Labisia pumila) leaves can provide ultraviolet protection with the content of active compounds of the flavonoid group. The research results can be scientific evidence for utilizing and developing products from Kacip Fatimah (Labisia pumila).
Characteristics and Antioxidant Activity of Limau Kuit Peel (Citrus hystrix) Extract with Variation of Extraction Solvent Rizki, Muhammad Ikhwan; Agustina, Ni Kadek Ayu; Sari , Anna Khumaira; Rahmatullah, Satrio Wibowo; Isnani, Nazhipah
Medical Laboratory Technology Journal Vol. 11 No. 1 (2025): June
Publisher : Poltekkes Kemenkes Banjarmasin Jurusan Analis Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/mltj.v11i1.650

Abstract

Limau kuit (Citrus hystrix) has been traditionally utilized for its therapeutic properties, particularly the antioxidant potential of its peel. Extraction is preferred for medicinal use, with solvent selection playing a critical role in determining the yield and concentration of bioactive compounds. This study aimed to assess the characteristics and antioxidant activity (IC₅₀ value) of Limau Kuit peel extract extracted with three different solvents. The research methods, starting with sample preparation, were carried out by drying Limau Kuit peel, then extraction using three different solvents: distilled water, ethanol 70%, and ethanol 96%. Extraction with distilled water solvent used the infusion method, while the ethanol solvent used the maceration method. The third extract was then characterized based on the parameters of percent yield, organoleptic testing, phytochemical screening, chromatography profile, and determination of total flavonoid levels. Antioxidant activity testing on the third extract using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. The study results showed that the third extract had the same shape, color, aroma, taste, and compound content: flavonoids, phenolics, alkaloids, and terpenoids. The results of thin-layer chromatography also showed no difference in the third extract. The characteristic differences were found in the parameters of percent yield and total flavonoid content.  The highest total flavonoid content of Limau Kuit (Citrus hystrix) peel extract was obtained using 70% ethanol (11.47% w/w), followed by 96% ethanol (6.39% w/w), and distilled water (2.82% w/w). Antioxidant activity, evaluated using the IC₅₀ value as the parameter, showed that the 70% ethanol extract exhibited the strongest activity (21.26 ppm, very strong), followed by the 96% ethanol extract (31.87 ppm, very strong), and distilled water extract (70.91 ppm, strong). This study concludes that 70% ethanol is the most effective solvent for extracting antioxidant-rich compounds from Limau Kuit peel, supporting its potential use in herbal formulations.
Education on Eye Ointments and Eye Drops for the Elderly at the Gedang Hanyar Health Center Setiawan, Deni; Fatimatuz Zahra; Khairunnisa; Ade Syarif Hakim; Satrio Wibowo Rahmatullah; Dita Ayulia Dwi Sandi
SAFARI :Jurnal Pengabdian Masyarakat Indonesia Vol. 3 No. 1 (2023): Januari : Jurnal Pengabdian Masyarakat Indonesia
Publisher : BADAN PENERBIT STIEPARI PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56910/safari.v3i1.343

Abstract

Eye drops and eye ointment are sterile drugs used to treat eye disorders. Using eye medications without using the instructions correctly can cause harm to the eyes. Elderly is a stage of life marked by a decrease in physical abilities including memory, so that it requires attention, especially in the use of special drugs. The purpose of this activity is to promote health regarding the use of eye drops and ointments targeting the elderly in the Gadang Hanyar Health Center area. Education is carried out through lectures with the help of leaflets. The target of the activity is elderly patients who are being treated at the Puskesmas during the activity. The results of the pretest showed that the patient's knowledge in general was good which was marked with a value of more than 70. The posttest was carried out after education using leaflets showed an increase in the knowledge value of ± 12-15 points from the initial value. Education on eye ointment and eye drops using leaflets significantly increases the knowledge of elderly respondents.
Penyuluhan Kesehatan Mental Pada Mahasiswa Tingkat Akhir Program Studi Farmasi Fakultas MIPA Universitas Lambung Mangkurat Hayatun Izma; Satrio Wibowo Rahmatullah; Muhammad Ikhwan Rizki; Anna Humaira
SAFARI :Jurnal Pengabdian Masyarakat Indonesia Vol. 3 No. 1 (2023): Januari : Jurnal Pengabdian Masyarakat Indonesia
Publisher : BADAN PENERBIT STIEPARI PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56910/safari.v3i1.361

Abstract

Mental health is as important as physical health. Final year students are inclined for mental health disorders associated with finishing their final project. This activity is to increase student’s knowledge and awareness of mental health so it can stimulate a healthy mental of students who are finishing final projects. This activity began with a pretest session to measure participant’s initial knowledge about mental health, presentation using experiental methods, discussion, sharing and Q&A session, and top it off with a posttest session. The results of this activity showed increase participant’s knowledge about mental health, from 57.84% to 95.47%.
Preclinical Study of n-Hexane Extract of Kapul Fruit (Baccaurea macrocarpa) as an Anti-Inflammatory Rizki, Muhammad Ikhwan; Rahmatullah, Satrio Wibowo; Izma, Hayatun; Isnani, Nazhipah; Ramadhani , Syahrizal
BORNEO JOURNAL OF PHARMASCIENTECH Vol 9 No 2 (2025): Borneo Journal Of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59053/bjp.v9i2.769

Abstract

Plants of the genus Baccaurea have long been traditionally used in folk medicine. Previous studies reported that the n-hexane extract of kapul fruit (Baccaurea macrocarpa) exhibited extreme antioxidant activity with an IC₅₀ value of 33.11 ppm. However, its potential anti-inflammatory activity has not been extensively investigated. The results demonstrated that all three doses of the n-hexane extract exhibited anti-inflammatory activity, as indicated by a reduction in edema volume. Among the tested doses, 600 mg/kg BW was the most effective ini decreasing edema volume. Statistical analysis using one-way ANOVA showed a significance value of 0.000, confirming a significant difference among the five treatment groups. Furthermore, post hoc analysis indicated that dose III did not differ significantly from the positive control but showed a significant difference compared to the negative control. Conversely, doses I and II exhibited significant differences when compared to both the positive and negative controls. These findings suggest that the n-hexane extract of B. macrocarpa fruit possesses anti-inflammatory activity, with the 600 mg/kg BW dose demonstrating the most potent effect, comparable to that of diclofenac sodium
PENINGKATAN KEPATUHAN MINUM OBAT MUAL MUNTAH DI RUMAH SINGGAH KANKER WILAYAH KALIMANTAN SELATAN Sari, Okta Muthia; Fikriyati, Nirmala; Kurniasari, Winda Tri; Izma, Hayatun; Rahmatullah, Satrio Wibowo; P.P, Aditya Maulana
JURNAL PENGABDIAN FARMASI DAN SAINS Vol. 2 No. 1 (2023): Oktober 2023
Publisher : Jurusan Farmasi FMIPA Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/jpsf.2023.v2.i1.16487

Abstract

Pasien paska kemoterapi sering mengalami efek samping yang mengganggu. Salah satu efek samping yang paling sering terjadi adalah gangguan mual dan muntah. Namun, pengetahuan terkait penggunaan obat mual muntah paska kemoterapi masih rendah. Tujuan pengabdian adalah meningkatkan kepatuhan minum obat mual muntah khususnya di Rumah Singgah Kanker. Metode pengabdian dengan penyuluhan dan dilaksanakan di Rumah Singgah Kanker wilayah Kalimantan Selatan. Peserta yang hadir sebanyak 10 orang. Setelah penyuluhan diperoleh tingkat pengetahuan peserta sebesar 90% pengetahuan tinggi dan 10% pengetahuan sedang. Dengan meningkatnya pengetahuan terkait maka dapat meningkatkan kepatuhan minum obat mual muntah pasien kanker.
Pemberdayaan Kader dan Lansia dalam Pengelolaan Serta Pemanfaatan Toga sebagai Upaya Dalam Mengatasi Hipertensi di Desa Sungai Batang Kabupaten Banjar Isnani, Nazhipah; Triyasmono, Liling; Rizki, Muhammad Ikhwan; Rahmatullah, Satrio Wibowo; Sandi, Dita Ayulia Dwi; Izma, Hayatun; Redanti, Hema Novita; Humaidy, Mizan; Amali, Dzikra Aulia
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 8, No 12 (2025): Volume 8 No 12 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v8i12.22551

Abstract

ABSTRAK Hipertensi merupakan salah satu penyakit tidak menular dengan prevalensi tinggi dan menjadi faktor risiko utama penyakit kardiovaskular. Salah satu upaya pencegahan yang dilakukan melalui pemberdayaan masyarakat dengan edukasi dan pemanfaatan Tanaman Obat Keluarga (TOGA). Kegiatan ini bertujuan untuk meningkatkan pengetahuan dan keterampilan kader serta lansia dalam pencegahan hipertensi di Desa Sungai Batang. Kegiatan ini dilakukan dengan metode ceramah interakif, diskusi, pemerian edukasi dan pelatihan pengolahan TOGA. Evaluasi pengetahuan peserta dilakukan menggunakan pre-test dan post-test, kemudian dianalisis secara deskriptif kuantitatif. Hasil dari kegiatan ini didapatkan peningkatan rata-rata pengetahuan peserta dari 87,14% pada pre-test menjadi 100% pada post-test, dengan nilai p=0,0001 yang menunjukkan perbedaan siginifikan. Selain itu, peserta juga memperoleh keterampilan dalam meracik ramuan herbal antihipertensi dari TOGA. Edukasi hipertensi dan pelatihan TOGA efektif meningkatkan pengetahuan dan keterampilan kader serta lansia dalam mendukung upaya promotif dan preventif pada penyakit hipertensi di Desa Sungai Batang. Kata Kunci: Hipertensi, Edukasi Kesehatan, Tanaman Obat Keluarga, Pemberdayaan Masyarakat.  ABSTRACT Hypertension is a non-communicable disease with a high prevalence and a significant risk factor for cardiovascular disease. One preventative measure is community empowerment through education and the use of Family Medicinal Plants (TOGA). This activity aims to improve the knowledge and skills of community health workers and the elderly in preventing hypertension in Sungai Batang Village. The activity used interactive lectures, discussions, educational presentations, and TOGA processing training. Participants' knowledge was evaluated using pre- and post-tests, then analysed descriptively using quantitative data. This activity showed an increase in average participant knowledge from 87.14% in the pre-test to 100% in the post-test, with a p-value of 0.0001 indicating a significant difference. Furthermore, participants also gained skills in preparing antihypertensive herbal concoctions from TOGA. Hypertension education and TOGA training effectively improved the knowledge and skills of community health workers and the elderly in supporting promotive and preventive efforts for hypertension in Sungai Batang Village. Keywords: Hypertension, Health Education, Family Medicinal Plants, Community Empowerment
Co-Authors Abdul Hadi Ade Syarif Hakim Adnan Syahrizal Agustina, Ni Kadek Ayu Ahmad Nazar Winarto Akbar, Depy Oktapian Akhmad Junaidi Amali, Dzikra Aulia Angelina Ayu Dela Anisa Desriyanti Anna Humaira Anna Khumaira Sari Apriyanti, Anna Astuti, Karunita Ika Aulia Rahmah Buih, Putri Helena Junjung Dahlia Syahrina Damayanti Rumondang Butar Butar Daniel Wisnugroho Deni Setiawan DENI SETIAWAN Difa Intannia Dyah Anggraeni Dyera Forestryana Dyera Forestryana Eka Fitri Susiani Endah Puwarastuti Endang Kurniasih Fadlilaturrahmah Fadlilaturrahmah, Fadlilaturrahmah Fanli Yudi Anwar Fanli Yudi Anwar Fatimatuz Zahra Fikriyati, Nirmala Fitria Febrianti Gultom, Luis Figo Guntur Kurniawan Hafiz Ramadhan Hafizah, Noor Hayatun Izma Helmina Wati Helsawati Helsawati Hendrya Legenda Herliana Dewi Herningtyas Nautika Lingga Humaidy, Mizan I Dewa Putu Pramantara I Dewa Putu Pramantara I Ketut Adnyana Isnaini, Nazhifah Izma, Hayatun Jenah, Rina Astiyani Khairina Maida Khairunnisa Khalifah, Sefa Nur Khoerul Anwar Khoirunnisa Muslimawati Kurniasari, Winda Tri Liling Triyasmono LINDA WAHYUNI Lisa Andina Lukman Hakim Lukman Hakim Madani, Al Mahendra, Rachul Ridho Mia Fitriana Muhamad Hepriatna Muhammad Ikhwan Rizki Muhammad Reza Fahlevi Muhammad Reza Pahlevi Mulia, Radha Eka Nasya Hafizah Nazhipah Isnani Noor, Riskan Nor Aida Normaidah, Normaidah Novia Novia Nurrahma, Ika Maulida Okta Muthia Sari P.P, Aditya Maulana Pratiwi, Desy Prima Happy Ratnapuri Putra, Aditya Maulana Perdana Putri, Indah Pebriani Qory Rahmat Nazri Rahma, Salsabila Fadiya Rahmayanti Fitriah Ramadhan, Fery Ramadhani , Syahrizal Ratna Restapaty Redanti, Hema Novita Risma Dian Ariyani Rosanti, Diah Aulia Sandi, Dita Ayulia Dwi Saputri, Revita Saragih, Triando Hamonangan Sari , Anna Khumaira Sari, Fitri Novita Sari, Okta Muthia Sari, Sindwi Rinanda Sari, Sri Oktaviani Silviana, Mega Siti Bahzah Siti Nurhaliza Leyla Susiani, Eka Fitri Syifa Auliani Tangkas, Hansel Hens Tjitradi, Sukhito Yohanes Tuti Misrina Wikaningtyas, Pratiwi Yusrinie Wasiaturrahmah