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Diah Riski Gusti
Department Of Chemistry, Faculty Of Science And Technology, Universitas Jambi, Jambi, Indonesia
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Journal : Pharmascience

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Potensi Ekstrak Etanol Daun Enceng Gondok (Eichhornia crassipes) sebagai Terapi Penyembuh Luka Bakar pada Tikus Putih Jantan Sani K, Fathnur; Putri, Andinni; Gusti, Diah Riski
Jurnal Pharmascience Vol 12, No 1 (2025): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v12i1.20326

Abstract

Luka bakar muncul akibat adanya cidera kontak lanngsung dengan sumber panas. Kondisi ini menjadi penyebab utama cidera dan kematian. Daun enceng gondok memiliki kandungan metabolit sekunder yang memiliki banyak efek farmakologi. Tujuan penelitian adalah menganalisis hasil potensi ekstrak enceng gondok secara in vivo sebagai terapi penyembuh luka bakar. Kelompok perlakuan dibagi menjadi 5 kolompok yaitu kontrol positif (Bioplacenton), kontrol negatif (Vaselin), konsentrasi ekstrak 2,5%, konsentrasi ekstrak 5%, dan konsentrasi ekstrak 7,5%. Parameter pengamatan yang digunakan adalah diameter luka bakar selama 14 hari dan hasil deskriptif histologi yang dikorbankan pada hari ke-15. Hasil penelitian menunjukkan bahwa semua perlakuan menunjukkan adanya perbedaan yang bermakna dengan konsentrasi terbaik adalah 7,5%, kemudian diikuti konsentrasi 5% dan 2,5%. Penelitian ini menjadi dasar pengembangan penelitian berikutnya dalam proses pengembangan produk penyembuh luka berbahan dasar ekstrak enceng gondok. Kata Kunci: Daun Enceng Gondok, Ekstrak, Histologi, Luka Bakar  Burns occur due to direct contact injury with a heat source. This condition is the leading cause of injury and death. Water hyacinth leaves contain secondary metabolites that have many pharmacological effects. This study aimed to analyze the potential results of water hyacinth extract in vivo as a burn healing therapy. The treatment group was divided into 5 groups: positive control (Bioplacenton), negative control (Vaseline), extract concentration of 2.5%; 5%; and 7.5%. The observation parameters used were the diameter of the burn wound for 14 days and the descriptive results of histology sacrificed on the 15th day. The results showed that all treatments showed significant differences, with the best activity concentration being 7.5%, followed by 5% and 2.5%. This study is the basis for developing subsequent research in developing wound healing products based on water hyacinth extract.
Co-Authors Abd. Mutakkin Abdul Manab Abdurrazaq Habib Abdurrazaq Habib Fadhilah Addion Nizori Ade Adriadi Ade Adriadi Adinda, Ladiva Adiningtyas Putri, Alya Agnes Vionita Yohana Agus Lintang Widodo Ahmad Sazali Alfernando, Oki Amanda Amanda Ance Pramai Shella Andini, Paziati Andrian Setyarestu Prayogi Anggi Cahaya Nirwana Angraini, Resti Indah Anisa Anisa Anjelli Putri Gunawan Annisa Dhita Syahrial apriansyah, rendi Ardian Salsa Rusmana Arif Nurrahman Armitha Dea Pradina Aulia Rahmi Azril Bagus, Adhitya Eko Betri Yanda Damris Muhammad Damris Muhammad Damris Muhammad Daniel Arsa Denny Prabawa, Aditya Dhian Eka Wijaya Dila Oktarise Dwina Djangkung Sumbogo Murti, Sri Dwi Savitri Nur Hidayah Dyah Kumalasari Edwin Permana Edwin Permana Eko Prasetyo Fadhilah, Abdurrazaq Habib Faizar Farid Faizar Farid Fajriaty, Rana Farizt Ichsan, Ahmad Fauzan Ramadhan Fitra Armando Frandi Mardiansyah Frastica Deswardani Frely Setiawan Sihombing Gunawan, Anjelli Putri Hamdan Maruli Siregar Harizon Harizon Haryanto Haryanto Henry Aritonang Hidayat, Ali Nurdin Indra Lasmana Tarigan Intan Lestari Intan Lestari Intan Lestari Intan Lestari Intan Lestasi Is Heriyanti, Septina Ismet, Lince Muis Khairunnisah, Resilta KurniawanSyah, Gilang Lenny Marlinda Lestari, Intan - Lestasi, Intan Lestasi, Uce M Ikrar Lagowa M. Rifqi Efendi M. Rusdi Maemonah, Maemonah Maharani Manulang, Ermita Meisa Martin Horas Parulian Butarbutar Martina Asti Rahayu Mastutik, Diah Maulana, Rico Gewana Resdy Menita Sinurat Mesa Sukmadani Rusdi Mia Aina Mia Aina Mirda Yanti, Fusia Moh Nabawi Moh Nabawi Mounir El Achaby Muhammad Arief Yamin Muhammad Haris Effendi Hasibuan Muhammad Rusdi Munawir Nursyahrobby Nabela Viviana Naswir, M. Nelson Nelson Nelson NEVIATY PUTRI ZAMANI Ngatijo Ngatijo Ngatijo Ngatijo Ngatijo Ngatijo Ngatijo Nindita Clourisa Amaris Susanto Nuralang Nuralang Oki Alfernando Oktarise Dwina, Dila Pradina, Armitha Dea Prasetio, Muhamad Reza Puspa Dwi Pratiwi Putra, Adrisma Juanda Putri Ramadhanti Putri Ramadhanti, Putri Putri, Andinni Qisthi, Zummul Qurrata Aini Ragil Johanda Rahma Aini Sapitri Rahmi Rahmi Rajagukguk, Yuli Evrianti Br Ratih Dyah Puspitasari Resilta Khairunnisah Restina Bemis Restina Bemis Revis Asra Ria Gracia Sibarani Safitri Safitri Safitri Safitri Sani K, Fathnur Sibarani, Ria Gracia Sihotang, Andreas Silvia Devi Eka Putri Sinurat, Menita Sriwati Azis Sudibyo Sudibyo Sudibyo Sudibyo Sukor, Mohd Zaki Susanto, Nindita Clourisa Amaris Syauqi, Rif’at Tri Haryati Tri Siswanto Uce Lestari Uce Lestari Uce Lestasi Wahyudi, Abdi Walidatur Rofiah, Yuliana Warni Warni Wulansari wulan Yanova, Shally Yehezkiel Dwi Wahyu Situmerang Yoga Andika Yohana, Agnes Vionita Zahar, Wahyudi