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All Journal International Journal of Public Health Science (IJPHS) Jurnal Sains dan Teknologi Jurnal Kebidanan Medical Laboratory Technology Journal THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST Meditory : The Journal of Medical Laboratory Jurnal Analis Kesehatan Jurnal Kesehatan Jurnal Bidan Cerdas Poltekita : Jurnal Ilmu Kesehatan Medicra (Journal of Medical Laboratory Science/Technology) Jurnal Pengabdian Kepada Masyarakat (JPKM) Tabikpun Poltekita: Jurnal Pengabdian Masyarakat Jurnal Pengabmas Masyarakat Sehat Muhammadiyah Medical Journal Ahmar Metakarya: Jurnal Pengabdian Masyarakat Jurnal Pengabmas Masyarakat Sehat JURNAL SKALA HUSADA: THE JOURNAL OF HEALTH Jurnal Pendidikan Kesehatan (e-Journal) (Medical Scientific Journal) MESINA Media Penelitian dan Pengembangan Kesehatan MEDICA (International Medical Scientific Journal) Jurnal Analis Kesehatan Kendari Jurnal Info Kesehatan
Heri Setiyo Bekti
Department Of Medical Laboratory Technology, Politeknik Kesehatan Kemenkes Denpasar, Denpasar, Bali, Indonesia And Center Of Excelence In Science And Technology, Polytechnic Of Health Denpasar, Bali, Indonesia
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Gambaran Kadar Asam Urat pada Ibu Hamil Wikantari, Ni Made Ayu Kerti; Bekti, Heri Setiyo; Krisna, Luh Ade Wilan
MESINA (Medical Scientific Journal) Vol 4, No 2 (2024): Medical Scientific Journal (MESINA)
Publisher : Universitas Muhammadiyah Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32502/msj.v4i2.6602

Abstract

Prevalensi asam urat pada ibu hamil, masih sering terjadi, dan dalam klinis lanjut dapat menyebabkan preeklampsia pada ibu hamil, hal ini dapat terjadi karena selama masa kehamilan terjadi penurunan kecepatan filtrasi glomerulus akibat adanya perubahan fungsi ginjal. Penelitian ini bertujuan untuk mengetahui gambaran kadar asam urat pada ibu hamil. Penelitian ini menggunakan metode deskriptif, yang dilaksanakan pada bulan Februari sampai Mei 2023 yang dilakukan di Puskesmas Penebel I Kecamatan Penebel Kabupaten Tabanan, dengan penarikan sampel menggunakan teknik non probability sampling dilakukan secara accidental sampling. Sampel dalam penelitian ini adalah ibu hamil di Puskesmas Penebel 1 Kecematan Penebel Kabupaten Tabanan. Pengukuran kadar asam urat menggunakan sampel darah kapiler dengan metode Point of Care Testing (POCT). Hasil penelitian ini menunjukkan bahwa terdapat 24 orang ibu hamil (70,6%) dengan kadar asam urat normal dan 10 orang ibu hamil (29,4%) dengan kadar asam urat tinggi. Kadar asam urat tinggi mayoritas diderita oleh ibu hamil usia ? 30 tahun (17%), paling banyak ditemukan pada usia kehamilan Trimester III (11,8%), paling banyak ibu hamil dengan indeks massa tubuh (IMT) obesitas (14,7%), dan ibu hamil dengan tekanan darah normal (29,4%). 
The Effectiveness of Green Grape Extract (Vitis vinifera) on Decreasing White Rat (Rattus novergicus) Triglycerides Levels Arwati, Ketut Lilik; Dewi, Ni Nyoman Astika; Bekti, Heri Setiyo; Dewi, Ni Wayan Rika Kumara; Saransi, Andi Udin
Muhammadiyah Medical Journal Vol 3, No 1 (2022): Muhammadiyah Medical Journal (MMJ)
Publisher : Faculty of Medicine and Health Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24853/mmj.3.1.1-9

Abstract

Background: Grapes (Vitis vinifera) are a source of antioxidants with high content of polyphenols and anthocyanins. Grape skin is rich in flavonoids. Anthocyanins and flavonoids have the effect of lowering blood triglyceride levels. Purposes: This study aimed to determine the effect of using green grape extract (GGE) in lowering triglyceride levels in the blood. Methods: Five groups of white male rats (Rattus novergicus) were divided into a negative control group (KN), positive control (KP), rats with a GGE dose of 100 mg/200g BW as P1, rats with a GGE dose of 250mg/200g BW as P2, and rats with GGE dose of 500 mg/200g BW as P3. Each group was given a hypercholesterolemic diet for five weeks. Groups P1, P2, and P3 were given GGE according to their respective doses for 14 days, then measured triglyceride levels in the blood. Results: The results showed that GGE 500mg/200g BW significantly reduced triglyceride levels in all treated mice. Conclusion: These results indicate that GGE has a great potential to treat dyslipidemia by lowering triglyceride levels in the blood.
A Patient with Suspect Chronic Myeloid Leukemia: A Case Report Dharmawaiswari, Anak Agung Ayu Ratih; Tedja, I Gusti Ayu Wiradari; Prianggandanni, Made Ayu Vita; Dharmawati, I Gusti Agung Ayu; Bekti, Heri Setiyo
Muhammadiyah Medical Journal Vol 5, No 2 (2024): Muhammadiyah Medical Journal (MMJ)
Publisher : Faculty of Medicine and Health Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24853/mmj.5.2.116-121

Abstract

Chronic myeloid leukemia (CML) is a type of cancer that starts in the blood-forming cells of the bone marrow. In contrast to other types of leukemia, chronic myeloid leukemia (CML) progresses slowly. This report covers a 52-year-old male patient who came to the emergency room at Wangaya Regional Hospital with weakness, nausea, and pallor. His weight had drastically decreased over the last few months. The clinical condition of the patient was that both eyes appeared anemic, and the abdominal examination revealed hepatomegaly. Complete blood count examination results showed the following results: leukocytes 222.73x103/µl, hemoglobin 7.3 g/dL, platelets 679x103/µl, neutrophil 87.5%, neutrophil/lymphocyte ratio 16.66%. The results of peripheral blood smear analysis showed that hyperleukocytosis, with the maturation stage of myelocyte cells with a percentage of myeloblasts 6%, promyelocytes 7%, myelocytes 6%, metamyelocytes 8%, neutrophils 10%, neutrophil segments 60%, other cells 3%. These examination results suggest chronic myeloid leukemia. However, to confirm the diagnosis, the BCR-ABL fusion protein must be expressed, which can be used to identify the presence or absence of the Philadelphia chromosome in patients diagnosed with chronic myeloid leukemia (CML).
Uric Acid Levels in Pregnant Women Haribaik, Anastaysia Annisa; Bekti, Heri Setiyo; Posmaningsih, Dewa Ayu Agustini
Muhammadiyah Medical Journal Vol 3, No 2 (2022): Muhammadiyah Medical Journal (MMJ)
Publisher : Faculty of Medicine and Health Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24853/mmj.3.2.53-59

Abstract

Background: Preeclampsia in pregnant women can be detected by measuring uric acid levels in the blood. This can occur due to changes in the hemodynamic system and decreased glomerular filtration rate during pregnancy. Purposes: This study aims to determine the description of uric acid levels in pregnant women at Community Health Centers I, South Denpasar. Methods: This study uses a descriptive observational method from April to May 2022, with 31 respondents obtained by non-probability sampling technique. Uric acid levels were measured by the Point of Care Testing (POCT) method. Results: The results showed 23 pregnant women (74.2%) with normal uric acid levels and eight pregnant women (25.8%) with high uric acid levels. Conclusion: High uric acid levels are most suffered by pregnant women aged 30 years (16.1%), most commonly found in the third trimester of pregnancy (16.1%), most pregnant women with a body mass index (BMI) more and obesity (9.7%), and pregnant women with normal blood pressure (22.6%).
Primers application with the Tso31 gene target in the molecular identification of Taenia solium Habibah, Nur; Bekti, Heri Setiyo; Kumara Dewi, Ni Wayan Rika; Rinawati, Luh Putu; Burhannuddin, Burhannuddin; Rakhmawati, Aprilia
Muhammadiyah Medical Journal Vol 2, No 1 (2021): Muhammadiyah Medical Journal (MMJ)
Publisher : Faculty of Medicine and Health Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (271.651 KB) | DOI: 10.24853/mmj.2.1.35-40

Abstract

Background: taeniasis is a zoonotic disease caused by Taenia spp. Human taeniasis caused by Taenia solium can be acquired after consumption of raw insufficiently cooked infected pork meat. Pigs are intermediate host for T.solium. Pigs acquired this infection by eating human feces that contained T.solium eggs. Pigs infected with T.solium can be transmitted to humans. Purposes: identification of T.solium in pig is important because it is indicator of T.solium transmission. Microscopic examination of T.solium eggs is considered less effective and efficient so that many other methods are developed for T.solium detection such as molecular and immunology. Method: This method used specific primer which can detect the Tso31 gene in T.solium. Tso31 gene is one of the most promising antigens to differentiate T.solium from T.saginata. Pig feces samples were taken by random sampling technique from 7 pig farms in Denpasar. Result: from the 30 samples, we found one sample that which gave a single amplification product of 234 bp. This indicates that the pig farms in Denpasar have been infected with T.solium. Conclusion: it is necessary to do meat inspection properly in the market as well as health education about the dangers and impacts of T.solium infection in the community.
The Efficacy of Green Grapefruit (Vitis Vinifera L) Extracts on Reducing Blood Glucose in a Diabetic Rat Model Habibah, Nur; Rofi'ah, Lisa Khofidatur; Bekti, Heri Setiyo; Dewi, Ni Nyoman Astika; Wilankrisna, Luh Ade; Posmaningsih, Dewa Ayu Agustini
Medical Laboratory Technology Journal Vol. 10 No. 2 (2024): December
Publisher : Poltekkes Kemenkes Banjarmasin Jurusan Analis Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/mltj.v10i2.606

Abstract

Diabetes mellitus (DM) is a chronic disease in which the pancreas cannot produce enough insulin hormone or when the body cannot use the insulin hormones properly. Green grapes contain flavonoids, anthocyanins, tannins, phenolic acids, and resveratrol and are high in antioxidants that are beneficial in lowering blood glucose levels. This study aims to determine the effectiveness of green grapefruit (Vitis vinifera L) extract in reducing blood glucose levels in a diabetic rat model. This research is a true experiment with a post-test-only control group design, using 24 male Wistar white rats aged 8-12 weeks and weighing 130-200 grams. The rats were divided into three groups: the positive control (I), green grapefruit extract (II), and normal group (III). The results showed that green grapefruit extract effectively reduced blood glucose levels in experimental animals by a percentage of 98.4%. The Independent T-Test showed a value of ρ>0.05 (0.533), so there was no significant difference in glucose levels between green grapefruit extract and positive control. This study concludes that green grapefruit extract was effective at 98.4% in reducing blood glucose levels in the diabetic rat model, compared to the positive control. The promising results of this study need to be continued by establishing a standardized optimal dose, assessing long-term effects, and implementing clinical trials to evaluate efficacy and safety.
Hubungan Kadar Kolesterol Total Dengan Tekanan Darah Pada Lansia Di Desa Peliatan Ubud Gianyar Ni Komang Sri Narayanthi; Sarihati, I Gusti Agung Dewi; Burhanuddin, Burhannuddin; Bekti, Heri Setiyo
Jurnal Analis Kesehatan Vol. 13 No. 2 (2024): Jurnal Analis Kesehatan
Publisher : Department of Health Analyst, Politeknik Kesehatan, Kementerian Kesehatan Tanjungkarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jak.v13i2.4735

Abstract

Penuaan sering menimbulkan masalah kesehatan pada sistem jantung dan pembuluh darah diantaranya adalah hipertensi. Kadar kolesterol yang tinggi dan hipertensi sering bersinergi dalam menyebabkan sindrom metabolik, yang menjadi prekursor penting dalam patogenesis penyakit kardiovaskular. Penelitian ini bertujuan untuk mengetahui hubungan antara kadar kolesterol total dengan tekanan darah pada lansia di Desa Peliatan Kecamatan Ubud Kabupaten Gianyar. Penelitian ini menggunakan pendekatan Cross Sectional dengan besar sampel adalah 43 responden. Pengambilan responden penelitian  ditentukan berdasarkan kriteria inklusi dan eksklusi. Pemeriksaan kadar kolesterol total dilakukan dengan menggunakan metode Point of Care Testing  easy touch, dan tekanan darah diukur menggunakan sphygmomanometer digital. Hasil penelitian ditemukan kadar kolesterol total yang  tinggi sebanyak 44,2 %, kadar ambang batas atas 25,6 % dan normal 30,2 %. Responden yang memiliki  tekanan darah tinggi 51,2 % dan normal 48,8 %, dari responden yang memiliki tekanan darah tinggi ditemukan 86,4% memiliki kadar kolesterol total kategori tinggi. Sedangkan responden dengan tekanan darah normal memiliki kadar kolesterol kategori normal dan ambang batas atas. Hasil uji chi-square menunjukkan nilai p = 0,001.  Dapat disimpulkan bahwa ada hubungan yang signifikan antara kadar kolesterol total dengan tekanan darah  pada lansia di Desa Peliatan Ubud Gianyar.
INCREASED PAROXONASE-3 LEVELS IN RATS FED HIGH CHOLESTEROL FEED WITH INDUCTION OF ETHANOL EXTRACT FROM KENIKIR LEAVES (COSMOS CAUDATUS) Sarihati, I Gusti Agung Dewi; Dhyanaputri, I Gusti Ayu Sri; Bekti, Heri Setiyo
Media Penelitian dan Pengembangan Kesehatan Vol. 33 No. 2 (2023): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v33i2.1838

Abstract

Ekspresi paraoxonase-3 (PON-3) pada HDL berhubungan dengan fungsi antioksidan HDL. PON3 merupakan protein yang penting dalam melindungi pembuluh darah dari aterosklerosis. Cosmos caudatus merupakan salah satu bahan alami yang berkhasiat meningkatkan kadar HDL. Tujuan penelitian adalah untuk menunjukkan pengaruh ekstrak etanol dari daun kenikir (C.caudatus) terhadap kadar PON-3 serum pada tikus yang diberi diet tinggi kolesterol. Penelitian dilakukan di Laboratorium Bio Mice and Rat dan Laboratorium Imunologi Poltekkes Kemenkes Denpasar. Penelitian ini menggunakan metode eksperimen sejati dengan Post-test Only Control Group Design. Sebanyak 24 ekor tikus jantan sebagai sampel dibagi menjadi 4 kelompok. Kelompok I (DS): tikus diberi pakan standar; kelompok 2 (DTK): tikus yang diberi diet tinggi kolesterol; kelompok 3 (Ss): tikus diberi pakan standar, diet tinggi kolesterol dan simvastatin 0,8 mg/kgBB, kelompok 4 (Cc): tikus diberi diet tinggi kolesterol dan ekstrak etanol daun kenikir 200mg/kg BB. Perlakuan diet tinggi kolesterol diberikan kepada kelompok DTK, Ss dan Cc selama 20 minggu. Pada minggu ke 17 hingga minggu ke 20, pada kelompok Ss diberikan tambahan simvastatin, kelompok Cc diberikan ekstrak etanol daun kenikir (C.caudatus), kelompok DS hanya diberikan pakan standar selama 20 minggu. Kadar serum PON3  diperiksa setelah 20 minggu perlakuan. Hasil menunjukkan kadar PON-3 serum tikus kelompok Cc lebih tinggi dibandingkan kelompok DTK. Uji one way anova menunjukkan bahwa ada perbedaan yang signifikan dengan p=0,006 dan kadarnya hampir sama dengan kelompok DS (p=0,891), namun lebih rendah dibandingkan Ss. Dari hasil tersebut disimpulkan bahwa terdapat pengaruh dari pemberian ekstrak etanol daun kenikir terhadap kadar PON-3 serum pada tikus.
PENINGKATAN KADAR KOLESTEROL PADA LANSIA DI PEDESAAN MENGWI: STUDI DESKRIPTIF CROSS-SECTIONAL Bekti, Heri Setiyo; Suwarriana, I Nyoman Astra; Arjani, Ida Ayu Made Sri
Jurnal Pendidikan Kesehatan (e-Journal) Vol. 11 No. 2 (2022): Jurnal Pendidikan Kesehatan (E-Journal)
Publisher : Poltekkes Kemenkes Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31290/jpk.v11i2.3596

Abstract

Increased cholesterol levels are one of the causes of coronary heart disease in most of the elderly. The purpose of this study was to describe total cholesterol levels in the elderly in mengwi village. The research method used is descriptive, the research was carried out from January to April 2021 with a total of 27 respondents obtained by purposive sampling technique. total cholesterol levels were measured by the point of care testing poct method. The results showed that of 27 respondents 59.3Percent had normal total cholesterol levels, 37 Percent threshold total cholesterol levels, and 3.7Percent high total cholesterol levels. abnormal total cholesterol is more commonly found in the age range of 71 until 75 years and is more experienced by elderly women 22.2 Percent. Based on the consumption of fatty foods, 51.9 Percent of the elderly rarely consume fatty foods and 37Percent of the elderly who have abnormal total cholesterol levels and are included in the category of frequently consuming fatty foods. Based on the results, it can be concluded that most of the elderly have normal total cholesterol levels. Abnormal total cholesterol levels are more common in the age range of 71 until 74 years and are more experienced by elderly women and 37 Percent of the elderly, including frequent consumption of fatty foods
PENYULUHAN KESEHATAN KECACINGAN DAN PEMERIKSAAN KADAR HEMOGLOBIN PADA ANAK SEKOLAH DASAR DI KECAMATAN UBUD-GIANYAR suyasa, ida bagus oka; Dharmawati, I Gst Agung Ayu; Bekti, Heri Setiyo
Jurnal Pengabmas Masyarakat Sehat Vol 7, No 1 (2025): JANUARI
Publisher : Poltekkes Kemenkes Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33992/jpms.v7i1.3801

Abstract

The prevalence of Soil Transmitted Helminths (STH) in Bali in 2004 reached 58.3% -96.8% in elementary school children. The priority problem to be corrected in this community service is the lack of knowledge of elementary school children regarding worms. This method of community service provides counseling, checking hemoglobin levels, checking for worm eggs in participants' feces and strengthening small doctors from SDN 1 Ubud. In the extension activities, there was an increase in participants' insight and knowledge, as seen from the increase in the number of participants who managed to get good grades, from 9.9% (pretest) to 97.5% (posttest). When checking hemoglobin levels, the majority of community service participants, 89.6% (69 people) had normal levels (9-14 gr/dl). Meanwhile, to check for the presence of worm eggs, the majority (72 people) of the community service participants did not find worm eggs (94.7%). One of the results of strengthening Little Doctors at SDN 1 Ubud is the birth of a work program (proker) to socialize worm prevention.  
Co-Authors Ade Dharmawan Agus Sri Lestari Amany, Hana Amirah ANDI UDIN SARANSI Anniwati, Leonita Aprilia Rakhmawati Aprilia Rakhmawati Aprilia Rakhmawati Aprilia Rakhmawati Arjani, Ida Ayu Made Sri Artawa, I Made Budi Arwati, Ketut Lilik Ayu Sukma Wedha Kristyanti Burhannuddin Burhanuddin, Burhannuddin Cahyana, I Made Dwipa Cok Dewi Widhya Hana Sundari Cok Dewi Widhya HS Cok Dewi Widhya HS Cokorda Dewi Widhya Hana Sundari Desak Gede Dwi Agustini Desak Made Lestari Dewi Dewa Ayu Niti Rahayu Putri Dewi, Kadek Indra Trisna Dewi, Ni Km Ayu Kusuma Dewi, Ni Nyoman Astika Dewi, Ni Putu Ditya Prabandari Dewi, Pande Putu Ayu Patria Dharmawaiswari, Anak Agung Ayu Ratih Dharmawati, I Gst Agung Ayu Dwija, Ida Bagus Nyoman Putra Farsida, Farsida Fusvita Merdekawati Ganjar Noviar Hardiyanta, I Made Yogi Haribaik, Anastaysia Annisa Hasfika, Essydhea Husna, Ismalia I Gusti Agung Ayu Dharmawati I Gusti Agung Ayu Dharmawati I Gusti Agung Dewi Sarihati I Gusti Agung Dewi Sarihati I Gusti Ayu Made Wulan Diantari I Gusti Ayu Sri Dhyanaputri I Gusti Ngurah Teja Pratama I Made Krishna Paramartha I Made Suarjana I Made Suarjana I Made Yogi Hardiyanta I Nyoman Jirna I Nyoman Purna I Wayan Karta I Wayan Karta Ida Ayu Krisna Dwipayanti Ida Ayu Sri Arjani Ida Bagus Oka Suyasa Ida Bagus Oka Suyasa Indriyani Indriyani Jannah Sofy Yanty Kadek Ika Surya Cahyani Kosasih, Audia Nizhma Nabila Kurniawan, Surya Bayu Luh Ade Wilan Krisna Luh Ade Wilankrisna Luh Putu Laksmi Mahastuti, Shri Ayu Purnami Mardhia Mardhia Marpaung, Nurasi Lidya E. Mastra , Nyoman Merdekawati, Fusvita Mochamad Choirul Hadi Ni Kadek Wahyu Diana Sari Ni Komang Erny Astiti Ni Komang Juniawati Ni Komang Omik Trianita Udiana Ni Komang Sri Narayanthi Ni Nyoman Astika Dewi Ni Putu Ditya Prabandari Dewi Ni Putu Ditya Prabandari Dewi Ni Putu Intan Maha Ayu Diyanti Ni Putu Lisa Anjani Ni Putu Yulia Rahma Dewi Ni Wayan Rika Kumara Dewi Noviar, Ganjar Nur Habibah Nur Habibah Nyoman Mastra Posmaningsih, Dewa Ayu Agustini Pradnya Yasa, Ni Putu Candra Dewi Prianggandanni, Made Ayu Vita Purwani Ruth, Grace Monica Putu Amrita Paramahita Putu Diah Wahyuni Rakhmawati, Aprilia Rike Syahniar Rinawati, Luh Putu Rindi, Oktavelendi Dhaneta Graha Rofi'ah, Lisa Khofidatur Ruspawan, I Dewa Made Savitri, Ni Putu Ayu Dani Sofi Yanty, Jannah Sudarmanto, I Gede Sudiadnyana, I Wayan Surya Bayu Kurniawan Suwarriana, I Nyoman Astra Suyasa, Ida Bagus Oka Swastini, I Gusti Agung Ayu Putu Tedja, I Gusti Ayu Wiradari Utami, Luh Mitha Ari Wikantari, Ni Made Ayu Kerti Wilankrisna, Luh Ade Yanty, Jannah Sofy