Claim Missing Document
Check
Articles

Clitoria ternatea Increases Milk Production in Dairy Cows by Inhibiting Dopamine Receptor D2: A Computational Study Leondro, Henny; Hadiani, Dimas Pratidina Puriastuti; Krisnaningsih, Aju Tjatur Nugroho; Lestari, Oke Anandika; Wahyudi, Didik; Gusmalawati, Dwi; Tribudi, Yuli Arif; Prihandini, Peni Wahyu
Indonesian Journal of Chemistry Vol 24, No 4 (2024)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.92920

Abstract

Dairy cow's milk is a primary commodity in various countries and increasing milk production in dairy cows is crucial. Clitoria ternatea has the potential to enhance milk production in dairy cows. This research aims to analyze C. ternatea's ability to induce milk production in dairy cows by targeting the DRD2 protein. The compounds within C. ternatea were screened for drug-likeness, toxicity, physicochemical properties, and membrane permeability parameters. The DRD2 protein in dairy cattle was modeled using homology modeling. The interaction stability between C. ternatea compounds and DRD2 was analyzed through molecular docking and dynamic using AutoDock Vina and Webgro. The study results revealed that among the 18 compounds, 5 passed the drug-likeness screening: citronellal, alpha-terpinolene, 15-methyxypaysine, allyl-crotyl-zinc, and 9,12-octadecadiynoic. These 5 compounds exhibited low toxicity and demonstrated easy penetration of lipid membranes. Molecular docking results indicated that citronellal and alpha-terpinolene had the lowest binding energy values and were bound to the inhibitor's side. Molecular dynamic simulations also confirmed the stability of the interaction between citronellal and alpha-terpinolene with DRD2. In conclusion, this research suggests that C. ternatea can potentially increase milk production in dairy cows by inhibiting the DRD2 protein, primarily through citronellal and alpha-terpinolene.
Diseminasi Budi Daya Ikan Baung dengan Keramba Jaring Apung dan Pakan Alami di Desa Kumba Kecamatan Jagoi Babang Kabupaten Bengkayang Yohana Sutiknyawati Kusuma Dewi; Oke Anandika Lestari; Widadi Padmarsari Soetignya; Thomas Candra Wasis Agung Sutignya; Brigita Ratna Harsanti
To Maega : Jurnal Pengabdian Masyarakat Vol 7, No 3 (2024): Oktober 2024
Publisher : Universitas Andi Djemma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35914/tomaega.v7i3.2848

Abstract

Desa Kumba terletak di Kecamatan Jagoi Babang Kabupaten Bengkayang merupakan salah satu desa di Kalimantan Barat yang berbatasan dengan Sarawak, Malaysia. Desa ini berada di daerah aliran sungai dimana merupakan habitat dari ikan baung. Ikan baung sangat diminati tidak hanya pasar lokal tetapi juga pasar luar negeri. Hasil panen ikan sangat bergantung pada kondisi alam dan belum termanajemen dengan baik karena adanya keterbatasan pengetahuan dan keterampilan dari mitra yaitu Kelompok Nelayan Tepian Kumbayang. Diseminasi budi daya ikan baung dengan teknologi Keramba Jaring Apung yang dikelola dengan pakan alami dari cacing sutra merupakan solusi untuk permasalah yang telah dipaparkan. Pelaksanaan diseminasi ini melalui tahapan orientasi lapangan, perijinan, dan sosialisasi; pelatihan dan pendampingan; serta evaluasi dan monitoring. Kegiatan pengabdian ini berhasil meningkatkan pengetahuan 70% peserta tentang budi daya ikan baung dengan KJA dan pakan alami, 15 orang mengerti cara mengelola ikan baung dengan KJA, dan 16 orang mengerti cara membudidayakan cacing sutra untuk pakan ikan.
Marmalade’s formulation of Madu Susu Orange (Citrus reticulata) on multiple concentrations of sucrose [Formulasi marmalade jeruk madu susu (Citrus reticulata) pada berbagai konsentrasi sukrosa] Agustina, Mulya; Dewi, Yohana Sutiknyawati Kusuma; Lestari, Oke Anandika
Jurnal Teknologi & Industri Hasil Pertanian Vol 30, No 1 (2025): Jurnal Teknologi & Industri Hasil Pertanian
Publisher : Teknologi Hasil Pertanian Fakultas Pertanian Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jtihp.v30i1.12-22

Abstract

Generally, the type of orange used in marmalade production is Sunkist oranges.  In this study, Madu Susu Oranges (Citrus reticulata), a local orange variety typically consumed fresh and rarely processed into products, were used as the raw material for making marmalade. Additionally, sucrose is a key ingredient that can influence the balance between pectin and water in marmalade, affecting its characteristics and making it a valuable topic for further research. The main objective of this research was to determine the best sucrose concentration in the Madu Susu Orange marmalade formulation based on its physicochemical and organoleptic characteristics. The research design used was a Randomized Block Design, one factor of the sucrose concentration level (75%, 80%, 85%, 90%, and 95%) in 5 repetitions. The data were analyzed using ANOVA and further tested with the HSD test at a 5% significance level. The determination of the best treatment was conducted using the effectiveness index method. The results showed that the best treatment was at a 95% sucrose concentration with a 0.77 treatment value (TTV). The physicochemical and sensory characteristics of the Madu Susu Orange marmalade at 95% sucrose concentration were: total acidity of 0.52%, pH 5.82, total soluble solids of 68.00%, moisture content of 20.87%, and color values L* 29.94, a* 9.87, b* 49.90. Sensory test results for the best treatment were color 3.80 (liked), texture 3.67 (liked), and taste 4.17 (very liked).
Antihyperglycemic and antioxidant activity of Bajakah herbal tea made from Bajakah rod-Tikung honey-Amblycarpa lime (jeruk Sambal) [Aktivitas antihiperglikemia dan antioksidan minuman teh herbal Bajakah yang dibuat dari madu Tikung-batang Bajakah-jeruk Sambal] Marina, Aristawipana; Lestari, Oke Anandika; Dewi, Yohana Sutiknyawati Kusuma
Jurnal Teknologi & Industri Hasil Pertanian Vol 30, No 1 (2025): Jurnal Teknologi & Industri Hasil Pertanian
Publisher : Teknologi Hasil Pertanian Fakultas Pertanian Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jtihp.v30i1.23-34

Abstract

Hyperglycemia is characterized by elevated blood glucose levels, defined as instant blood glucose exceeding 200 mg/dL or fasting blood glucose surpassing 126 mg/dL. This condition has the potential to increase free radicals in the body. Using herbal ingredients or herbal drinks can also be a way to control blood glucose and free radicals. The Uncaria genus has functional anti-diabetic properties because it contains alkaloids and flavonoid compounds with antihyperglycemic and antioxidant effects. This study aimed to measure the antioxidant and antihyperglycemic potential of bajakah herbal tea with its raw materials (bajakah wood extract, honey, and Amblycarpa lime (jeruk Sambal)). The formulation of Bajakah herbal tea consists of 19.32 g Amblycarpa lime (jeruk Sambal), 46.38 g Bajakah rod extract, and 57.97 g honey. Antioxidant activity was achieved using the 2,2-diphenyl-1-picrylhydrazyl or DPPH method, and antihyperglycemic methods were used, such as the Oral Glucose Tolerance Test (OGTT). Physical characteristics are also tested for pH, color, and total dissolved solids. Data was analyzed using one-way ANOVA. The results showed that the combination of Bajakah-based herbal drinks, Bajakah herbal tea (123.67 g or equivalent to a carbohydrate content of 50 g), and the single preparation did not have antihyperglycemic activity. However, bajakah herbal tea has the highest antioxidant activity compared to its raw materials.
Aktivitas Antioksidan dan Karakteristik Sensori Madu Kelulut Asal Kalimantan Barat Utami, Dwi; Dewi, Yohana Sutiknyawati Kusuma; Lestari, Oke Anandika
Jurnal Teknologi Pangan Vol 18, No 2 : DESEMBER 2024
Publisher : UPN VETERAN JAWA TIMUR

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33005/jtp.v18i2.4769

Abstract

Madu adalah cairan alami yang berasal dari nektar bunga dan sekresi tanaman oleh lebah, salah satunya berasal dari lebah kelulut (Trigona sp.). Madu yang dipasarkan saat ini memiliki karakteristik dan kualitas yang beragam karena berasal dari berbagai daerah yang berbeda-beda. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan dan tingkat kesukaan madu kelulut asal Desa Parit Baru, Desa Jawa Tengah dan Desa Galang. Penelitian dilakukan berdasarkan Rancangan Acak Kelompok dengan satu faktor yaitu perbedaan asal daerah madu kelulut dengan geografis yang berbeda (K). Hasil Penelitian menunjukkan bahwa komponen fitokimia yang terkandung didalam madu kelulut asal Desa Parit Baru, Desa Jawa Tengah dan Desa Galang terdiri dari fenol, flavonoid, alkaloid, tanin dan terpenoid. Nilai aktivitas antioksidan tertinggi berasal dari madu kelulut asal Desa Parit Baru sebesar 41%. Nilai total flavonoid tertinggi berasal dari madu kelulut asal Jawa Tengah sebesar 27,53 mg QE/g. Nilai total fenol tertinggi berasal dari madu kelulut asal Desa Galang sebesar 14,15 mg GAE/g. Tingkat kesukaan ketiga madu kelulut terhadap warna, aroma, dan rasa menunjukkan rentang skor 3,30 hingga 3,83, yaitu agak suka hingga suka.
SWEETENER FORMULATION for MAKING JAM SHEETS COMBINATION of PINEAPPLE (Ananas Comosus L. Merr) and GREEN MUSTARD (Brassica Juncea L.) Stephanie, Akuilla; Lestari, Oke Anandika; Priyono, Suko
JURNAL BIOINDUSTRI (JOURNAL OF BIOINDUSTRY) Jurnal Bioindustri: Vol 7 No. 1 (2024)
Publisher : Universitas Trilogi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31326/jbio.v7i1.2112

Abstract

Pineapple and green mustard are fruits and vegetables that have the potential to be processed into jam sheets. Sweetener is one of the components used in jam making. This study aims to obtain the best sweetener formulation on the physicochemical characteristics and organoleptic properties of pineapple-cabbage jam. The research was conducted using the Randomized Group Design (RAK) method with 1 (one) research factor, namely the concentration of sucrose, honey, and stevia sweeteners. The variables observed were water content, total acid, color, reducing sugar and organoleptic test. The resulting data were analyzed by ANOVA test and if the data had a significant effect, the BNJ further test was carried out at the 5% level. The best treatment in the research of pineapple-cabbage sheet jam was found in the sweetener treatment 120 g sucrose, 45 g honey, and 0,015 g stevia. Pineapple mustard sheet jam with various formulations of sucrose, honey, and stevia sweeteners influenced the moisture content, total acid, reducing sugar, color, and sensory properties in the form of color, texture, and sweetness.
RATIO OF BROWN RICE FLOUR AND MUNG BEAN FLOUR IN THE MAKING OF SEMPRONG CAKE Sahid, Emif Rezqia; Lestari, Oke Anandika; Hartanti, Lucky
JURNAL BIOINDUSTRI (JOURNAL OF BIOINDUSTRY) Jurnal Bioindustri: Vol 7 No. 1 (2024)
Publisher : Universitas Trilogi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31326/jbio.v7i1.2113

Abstract

Semprong is one of Indonesia's signature cookies with a crunchy texture and roll-like shape. The main raw material commonly used in kue semprong is white rice flour. Brown rice is an alternative to rice flour for making kue semprong because its utilization in the food industry sector is still very limited. Rice, which is included in the cereal group, is low in the amino acid lysine, so it would be better if it is paired with other raw materials, such as beans such as green beans. The objective of this study was to obtain the right ratio of brown rice flour and mung bean flour to produce the best abacus cake formulation based on physicochemical and sensory characteristics. Based on the results of the research, the best abacus formulation with the highest score is P3, which is a ratio of 60% brown rice flour and 40% mung bean flour with a moisture content of 3.30%, protein content of 16.80%, ash content of 1.56%, color L* 23.26, color a* 6.62, color b* 7.54, has a yellow color, distinctive aroma of brown rice, crunchy texture, and savory taste.
RATIO OF BROWN RICE FLOUR AND MUNG BEAN FLOUR IN THE MAKING OF SEMPRONG CAKE Sahid, Emif Rezqia; Lestari, Oke Anandika; Hartanti, Lucky
JURNAL BIOINDUSTRI (JOURNAL OF BIOINDUSTRY) Jurnal Bioindustri: Vol 7 No. 1 (2024)
Publisher : Universitas Trilogi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31326/jbio.v7i1.2113

Abstract

Semprong is one of Indonesia's signature cookies with a crunchy texture and roll-like shape. The main raw material commonly used in kue semprong is white rice flour. Brown rice is an alternative to rice flour for making kue semprong because its utilization in the food industry sector is still very limited. Rice, which is included in the cereal group, is low in the amino acid lysine, so it would be better if it is paired with other raw materials, such as beans such as green beans. The objective of this study was to obtain the right ratio of brown rice flour and mung bean flour to produce the best abacus cake formulation based on physicochemical and sensory characteristics. Based on the results of the research, the best abacus formulation with the highest score is P3, which is a ratio of 60% brown rice flour and 40% mung bean flour with a moisture content of 3.30%, protein content of 16.80%, ash content of 1.56%, color L* 23.26, color a* 6.62, color b* 7.54, has a yellow color, distinctive aroma of brown rice, crunchy texture, and savory taste.
SWEETENER FORMULATION for MAKING JAM SHEETS COMBINATION of PINEAPPLE (Ananas Comosus L. Merr) and GREEN MUSTARD (Brassica Juncea L.) Stephanie, Akuilla; Lestari, Oke Anandika; Priyono, Suko
JURNAL BIOINDUSTRI (JOURNAL OF BIOINDUSTRY) Jurnal Bioindustri: Vol 7 No. 1 (2024)
Publisher : Universitas Trilogi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31326/jbio.v7i1.2112

Abstract

Pineapple and green mustard are fruits and vegetables that have the potential to be processed into jam sheets. Sweetener is one of the components used in jam making. This study aims to obtain the best sweetener formulation on the physicochemical characteristics and organoleptic properties of pineapple-cabbage jam. The research was conducted using the Randomized Group Design (RAK) method with 1 (one) research factor, namely the concentration of sucrose, honey, and stevia sweeteners. The variables observed were water content, total acid, color, reducing sugar and organoleptic test. The resulting data were analyzed by ANOVA test and if the data had a significant effect, the BNJ further test was carried out at the 5% level. The best treatment in the research of pineapple-cabbage sheet jam was found in the sweetener treatment 120 g sucrose, 45 g honey, and 0,015 g stevia. Pineapple mustard sheet jam with various formulations of sucrose, honey, and stevia sweeteners influenced the moisture content, total acid, reducing sugar, color, and sensory properties in the form of color, texture, and sweetness.
EFFECT OF THE RATIO OF BROWN RICE FLOUR AND MUNG BEAN FLOUR ON THE PHYSICOCHEMICAL AND SENSORY CHARACTERISTICS OF SEMPRONG CAKE Sahid, Emif Rezqia; Lestari, Oke Anandika; Hartanti, Lucky
JURNAL BIOINDUSTRI (JOURNAL OF BIOINDUSTRY) Jurnal Bioindustri: Volume 7 Nomor 1 `
Publisher : Universitas Trilogi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31326/jbio.v7i1.2135

Abstract

Brown rice flour and mung bean flour are food ingredients that are rarely used but have potential as ingredients in making semprong cakes. The purpose of this study is to obtain the right ratio of brown rice flour and mung bean flour to produce the best semprong cake formulation based on physicochemical and sensory characteristics. The research was conducted using the Group Random Design (RAK) method with one factor, namely the ratio of brown rice flour and mung bean flour. The observed parameters include moisture content, protein content, ash content, color, and sensory analysis. The data obtained was analyzed using ANOVA and if it was effective, further tests were carried out using the honest real difference test (BNJ) with a level of 5%. Based on the results of the semprong research, the best formulation is semprong with a ratio of 60% brown rice flour and 40% mung bean flour with a moisture content of 3.30%, protein content of 16.80%, ash content of 1.56%, color L* 23.26, color a* 6.62, color b* 7.54, as well as sensory scores for color 4 (dark chocolate), aroma 3 (typical of brown rice), texture 4 (crispier), and taste 4 (more savory).
Co-Authors Agus Setiyono Agustina, Mulya Aju Tjatur Nugroho Krisnaningsih Aklisa, Seskia Amalia Nur Aktavia, Risti Ananda, Dzikri Maizan Anggraeni, Wanda Putri Apriani, Sri Devi Aprillia, Nelvy Regina Dwi Arif Hidayatullah Aruntari Junimdiyan Aurelia, Michelle Putri Billhaq, Sabila Meirizqina Boangmanalu, Tania Roitona Brigita Ratna Harsanti brigitta ersa pancarwani Candra Wasis Agun CHANDRA, DEFRI ORCHIO Dewi, Yohana Kusuma Dharmawan, Hanief Dharmawan Dhitasari, Rochmah Mira Didik Wahyudi Dwi Fatmawati, Dwi Dwi Gusmalawati Dwi Raharjo Dzul Fadly Emelda, Plaviana Erawati, Erawati Eva Mayasari Fabiola, Vonny Faiza, Arnida Nur Farahiyati, Lana Febrianti, Auliadini Feri Kusnandar Fitriani, Wini Dwi Gian Melinda Saputri Hadiani, Dimas Pratidina Puriastuti Hasbullah Hasbullah Hasbullah Ifwarisan Defri Komariyati Komariyati Komariyati Komariyati Kurniawan, Mikhael Ricky Leondro, Henny Lestari, Yessi Lucky Hartanti Lucky Hartanti Lucky Hartanti, Lucky Maherawati Maherawati, Maherawati Mardiana Putri Maria Ulfa Marina, Aristawipana Marito, Yohanes Mastira, Susi Musa Alfius Nabilah, Uray Ulfah Nancy Dewi Yuliana Neli Muflihah Nopita Sari Nopita Sari Nur Endah Saputri Nurhasanah Nurhasanah Nurmainah Nurmainah Oktaviani, Sulha Rahmi Palupi, Nurheni Sri Peruwany, Gabriela Plaviana Emelda Prihandini, Peni Wahyu purwayanti, sulvi Putri, Audy Fadzilla PUTRI, MARDIANA Rudin, Iswandi Sapta Sahid, Emif Rezqia Sakapani, Patricia Dayu Salsabhilla, Keisya Aura Saputri, Gian Melinda Saputri, Nur Endah Sari, Diah Puspita Sari, Sandytia Permata Satrijo Saloko Situmorang, Ruth Karen Vania SKD, Yohana Sri Widowati Stephanie, Akuilla Suko Priyono Suko Priyono Surya Abi Alfariz Syafitri, Dhea Syarifah Nabila Taneasy, Ian Tanjung, Safrina Arsi Sekar Th. Candra Wasis Agung Sutignya Tri Rahayuni Utami, Dwi Vonny Fabiola Warong, Sepiana Debora Widadi Padmarsari Soetignya Widoyo, Nurman Alif Yohana S. Kusuma Dewi Yohana S.K. Dewi Yohana Sutiknyawati Kusuma Dewi Yohana Sutiknyawati Kusuma Dewi Yohanes Marito Yuli Arif Tribudi Zukhruf, Syaqinah Az