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Gambaran Darah Rutin dan Kualitas Hidup Domain Fisik Penderita Gagal Ginjal Kronik Terminal nurkamila, -; Hidayati, Titiek
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 13, No 2 (2013)
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v13i2.1062

Gagal ginjal kronik terminal (GGKT) merupakan kerusakan ginjal yang progresif. Gambaran darah rutin (Angka Leukosit, kadar Hemoglobin, Angka Trombosit) merupakan pemeriksaan untuk mengetahui fungsi ginjal karena menggambarkan estimated glomerular filtration rate (eGFR), konsentrasi dan kandungan darah serta kreatinin. Penelitian ini bertujuan untuk mengetahui hasil pemeriksaan darah rutin dan kualitas hidup domain fisik penderita gagal ginjal terminal. Rancangan penelitian ini adalah case control. Subjek penelitian adalah 27 pasien GGKT RSUD Panembahan Senopati Bantul Yogyakarta ( kelompok kasus) dan 54 pasien non GGKT (kelompok kontrol). Kelompok kasus adalah pasien gagal ginjal kronis di RSUD Panembahan Senopati Bantul yang merupakan WNI dan menjalani terapi hemodialisis sejak bulan Februari-April 2012. Data diperoleh dengan melihat rekam medis pasien, pengisian kuesioner dan pengambilan sampel darah. Analisis bivariat dan multivariat dilakukan dengan perhitungan uji kai kuadrat dan uji regresi logistik untuk perhitungan secara statistik hubungan jenis kelamin, usia, AL, Hb, dan AT dengan kualitas hidup doman fisik pasien. Hasil analisis bivariat dan multivariat menunjukkan nilai signifikansi pada AL (P= 0,016; B=-1.498) dan Hb (P=0,010; B=-1.679) dengan kualitas hidup domain fisik baik dan buruk pasien GGKT. Disimpulkan bahwa terdapat hubungan yang signifikan antara Angka Leukosit (AL) dan kadar Hemoglobin (Hb) dengan kualitas hidup domain fisik penderita GGKT.Â End stage renal disease (ESRD) is a progressive kidney damage. Routine Blood examination feature (white blood count, hemoglobin and platelet count) is kind of examination used to investigate the kidney function because it describes the eGFR (estimated Glomerular Filtration Rate, the concentration and the content of blood, as well as the amount of creatinine. This study aims to determine the routine blood tests with physical domains of quality of life people with terminal renal failure. This researchâ€™s design is case control. The subjects are the patients from RSUD Panembahan Senopati Bantul Yogyakarta, 27 ESRD patients (case group) and 54 non- ESRD patients (control group). Data collected from patients Medical Record, questionnaire, and obtaining the blood sample. Bivariate and multivariate data analysis was performed and calculated with chiÂ squareÂ testÂ and logistic regression to statistically calculate the sex, age, white blood count, hemoglobin and platelet count with patientâ€™s physical domain of quality of life. The bivariate and multivariate data analysis show significant result on WBC (P= 0,016; B=-1.498) and Hb (P=0,010; B=-1.679). The study suggests a significant relation between WBC and amount of blood Hemoglobin with physical domain of Quality of Life on end stage renal disease

Kejadian Luar Biasa Campak Di SD Pugeran dan SMPN II Kecamatan Mantrijeron Kota Yogyakarta Pasca Gempa September 2006 Hidayati, Titiek
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 9, No 1 (s) (2009)
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v9i1 (s).1624

The measles outbreak epidemiology research conducted in Pugeran elementary school and state junior high school II Mantrijeron subdistric of Yogyakarta after the earthquake in Daerah Istimewa Yogyakarta (DIY). The aims of this study is to assess the picture of measles outbreaks in Pugeran elementary school and state junior high school II after the earthquake in Yogyakarta. The research method used cross sectional design with analitic type. The collected data survey used questionnaire that filled by researcher and direct observation. Determination of the status measles outbreak used clinical diagnostic guidelines of Indonesia ministry health. Elisa laboratory tests conducted to confirm the cause of seroimunologis outbreak. Data obtained were analyzed to reveal the picture outbreaks, causes and distribution of outbreaks by time, place and person. There were 19 students of600 students, with measles outbreaks composed 15 students in elementary school and 4 students yunior high school subdistrict Mantrijeron in September 2006 (attack rate 3%). There was not found the patient dying or case fatality rate is zero. Clinical manifestations of measles outbreaks were fever (100%), rash (100%), cough (60%) and colds (60%). There weren â€™tfound any clinical manifestations of red eyes conjunctivitis or shortness of breath. 19 measles patients consists of 13 men and 6 women. The patient residence covered 13 patients of the Mantrijeron district, 4 patients of Sewon district, and 2 patients of Wirobrajan district. Patientâ€™s blood serology tests showed that rubella immunoglobulin (Ig) G positive, whereas for measles Ig G negative. It can concluded that there has been an outbreak of measles in the post-earthquake Yogyakarta in Yogyakarta.Telah dilakukan penelitian penyidikan epidemiologis kej adian luar biasa (KLB) campak di SD Pugeran dan SMPN II Kecamatan Mantrij eron Kota Yogyakarta setelah terj adinya gempa bumi di Yogyakarta. Tujuan penelitian ini adalah untuk mengetahui gambaran KLB campak di SD Pugeran dan SMPN II Kecamatan Mantrij eron Kota Yogyakarta yang terj adi setelah peristiwa gempa bumi di DIY. Penelitian KLB ini merupakan penelitian epidemiologi observasional yang dilaksanakan secara cross sectional dengan metode survey. Survey dilakukan pada 600 siswa di SD Pugeran dan SMPN II Kecamatan Mantrijeron Kota Yogyakarta. Penetapan status KLB campak menggunakan kriteria diagnosis klinik menggunakan pedoman penetapan KLB yang dkeluarkan Depkes RI, juga dilakukan tes laboratorium seroimunologis untuk mengkonfirmasi penyebab KLB. Data yang diperoleh dianalisa untuk mengungkapkan gambaran KLB, penyebab dan distribusi KLB berdasarkan waktu, tempat dan orang. Dari 600 siswa yang disurvey telah terj adi KLB campak pada 19 siswa, 15 siswa di SD Pugeran dan 4 siswa di SMPN II Kecamatan Mantrijeron Kota Yogyakarta pada September 2006 (attack rate 3 %). Tidak diketemukan adanya korban KLB yang meninggal atau case fatality rate adalah nol. Manifestasi klinis KLB campak yang muncul pada para korban adalah demam (100%), rash (100%), batuk (60%) dan pilek (60%). Tidak ditemukan adanya manifestasi klinik mata merah (konjungtivitis) maupun sesak nafas. Dari 19 korban yang mengalami campak terdiri dari 13 pria dan 6 wanita, 13 korban dari kecamatan Mantrijeron, 4 korban dari kecamatan Sewon, 1 korban dari kecamatan kraton dan 1 korban dari kecamatan Wirobrajan. Uji serologi darah penderita menunjukkan bahwa IgG rubella positif, sedangkan IgG untuk measles negative. Berdasarkan hasil uji serologi darah diketahui bahwa penyebab KLB campak adalah rubella. Dapat disimpulkan bahwa telah terj adi KLB campak di Yogyakarta paska gempa bumi di Yogyakarta.

Pengaruh Pelatihan Gizi Metode Roleplay dan Audiovisual terhadap Tingkat Pengetahuan dan Sikap tentang Gizi di Wilayah Kerja Puskesmas Kasihan I, Bantul Hidayati, Titiek; Jati, Dhara Indah Kartika
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 11, No 3 (2011)
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v11i3.992

Malnutrisi yaitu ketidak seimbangan selular antara pemberian asupan nutrisi dan energi yang dikeluarkan. Upaya perbaikan gizi sudah banyak dilakukan di Puskesmas, salah satunya konseling. Tujuan penilitian ini adalah untuk mengetahui pengaruh pelatihan terhadap tingkat pengetahuan dan sikap tentang gizi di wilayah kerja Puskesmas Kasihan I, Bantul. Desain penelitian yang digunakan adalah quasi eksperimental dengan pre test-post test control group design dengan metode Roleplay dan metode audiovisual. Subyek penelitian ini adalah 30 ibu balita dengan status gizi kurang yang dibagi menjadi 2 kelompok (kelompok pelatihan dan kontrol). Analasis data menggunakan uji independent dan paired sample t-test. Hasil analisis statistik menggunakan paired sample t-test terhadap nilai rerata pre test dan post test pengetahuan serta sikap menunjukkan peningkatan, kenaikan rerata pengetahuan pada kelompok kontrol -0,4 tetapi tidak bermakna 0,57, kelompok pelatihan -3,1 yang bermakna 0,00 (p0,05). Kenaikan rerata sikap pada kelompok kontrol 0,73 tetapi tidak bermakna 0,76, kelompok pelatihan -6,2 yang bermakna 0,00 (p0,05). Pengaruh pelatihan gizi dengan terhadap tingkat pengetahuan dan sikap dengan independet sample t-test p=0,013 untuk pengetahuan dan p=0,001 untuk sikap (p0,05). Hal ini dapat disimpulkan bahwa terdapat pengaruh pelatihan gizi dengan metode Roleplay dan audiovisual terhadap tingkat pengetahuan tentang gizi di wilayah kerja Puskesmas Kasihan I, Bantul. Kata kunci: Roleplay, Audiovisual, Pengetahuan, Gizi

Kejadian Luar Biasa Campak Di SD Pugeran dan SMPN II Kecamatan Mantrijeron Kota Yogyakarta Pasca Gempa September 2006 Hidayati, Titiek
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 9, No 1 (s) (2009)
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v9i1 (s).1624

The measles outbreak epidemiology research conducted in Pugeran elementary school and state junior high school II Mantrijeron subdistric of Yogyakarta after the earthquake in Daerah Istimewa Yogyakarta (DIY). The aims of this study is to assess the picture of measles outbreaks in Pugeran elementary school and state junior high school II after the earthquake in Yogyakarta. The research method used cross sectional design with analitic type. The collected data survey used questionnaire that filled by researcher and direct observation. Determination of the status measles outbreak used clinical diagnostic guidelines of Indonesia ministry health. Elisa laboratory tests conducted to confirm the cause of seroimunologis outbreak. Data obtained were analyzed to reveal the picture outbreaks, causes and distribution of outbreaks by time, place and person. There were 19 students of600 students, with measles outbreaks composed 15 students in elementary school and 4 students yunior high school subdistrict Mantrijeron in September 2006 (attack rate 3%). There was not found the patient dying or case fatality rate is zero. Clinical manifestations of measles outbreaks were fever (100%), rash (100%), cough (60%) and colds (60%). There weren â€™tfound any clinical manifestations of red eyes conjunctivitis or shortness of breath. 19 measles patients consists of 13 men and 6 women. The patient residence covered 13 patients of the Mantrijeron district, 4 patients of Sewon district, and 2 patients of Wirobrajan district. Patientâ€™s blood serology tests showed that rubella immunoglobulin (Ig) G positive, whereas for measles Ig G negative. It can concluded that there has been an outbreak of measles in the post-earthquake Yogyakarta in Yogyakarta.Telah dilakukan penelitian penyidikan epidemiologis kej adian luar biasa (KLB) campak di SD Pugeran dan SMPN II Kecamatan Mantrij eron Kota Yogyakarta setelah terj adinya gempa bumi di Yogyakarta. Tujuan penelitian ini adalah untuk mengetahui gambaran KLB campak di SD Pugeran dan SMPN II Kecamatan Mantrij eron Kota Yogyakarta yang terj adi setelah peristiwa gempa bumi di DIY. Penelitian KLB ini merupakan penelitian epidemiologi observasional yang dilaksanakan secara cross sectional dengan metode survey. Survey dilakukan pada 600 siswa di SD Pugeran dan SMPN II Kecamatan Mantrijeron Kota Yogyakarta. Penetapan status KLB campak menggunakan kriteria diagnosis klinik menggunakan pedoman penetapan KLB yang dkeluarkan Depkes RI, juga dilakukan tes laboratorium seroimunologis untuk mengkonfirmasi penyebab KLB. Data yang diperoleh dianalisa untuk mengungkapkan gambaran KLB, penyebab dan distribusi KLB berdasarkan waktu, tempat dan orang. Dari 600 siswa yang disurvey telah terj adi KLB campak pada 19 siswa, 15 siswa di SD Pugeran dan 4 siswa di SMPN II Kecamatan Mantrijeron Kota Yogyakarta pada September 2006 (attack rate 3 %). Tidak diketemukan adanya korban KLB yang meninggal atau case fatality rate adalah nol. Manifestasi klinis KLB campak yang muncul pada para korban adalah demam (100%), rash (100%), batuk (60%) dan pilek (60%). Tidak ditemukan adanya manifestasi klinik mata merah (konjungtivitis) maupun sesak nafas. Dari 19 korban yang mengalami campak terdiri dari 13 pria dan 6 wanita, 13 korban dari kecamatan Mantrijeron, 4 korban dari kecamatan Sewon, 1 korban dari kecamatan kraton dan 1 korban dari kecamatan Wirobrajan. Uji serologi darah penderita menunjukkan bahwa IgG rubella positif, sedangkan IgG untuk measles negative. Berdasarkan hasil uji serologi darah diketahui bahwa penyebab KLB campak adalah rubella. Dapat disimpulkan bahwa telah terj adi KLB campak di Yogyakarta paska gempa bumi di Yogyakarta.

Pengaruh Ekstrak-Etanol Biji Jinten hitam (Nigella sativa L.) terhadap Mortalitas Larva Aedes aegypti Purwoko, Akhmad Edy; Hidayati, Titiek
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 9, No 2 (2009)
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v9i2.1600

The various type of plant used as the biological resource which is necessary for human being. Many kind of plan was exploited as an insecticidal, because of the active ingredient which present in the plant. Nigella Sativa was one of the plants which relatively peaceful and not dangerous to the environment, but its potential to restrain insect specifically for mosquito have never been studied. The purpose of this research is to know the influence of ethanol extract of Nigella sativa to the Ae. aegypti larvae mortality. This research conducted the mortality test of mosquito according the WHO techniques for susceptibility of insecticide on mosquitoes use 9 concentration of Nigella sativa extract: 1%; 0,8%; 0,6%; 0,4%; 0,3%; 0,2%; 0,1%; 0,05%; 0,025% and 0%. The larva mortality data analyzed with Anava and analyze with probit analysis to determine the value LC50 (in 24 hour). The result of mortality test shows that the excelsior of ethanol extract of Nigella sativa concentration caused larva death especially in 24 hour first. At highest concentration that is 1% more than 95% larva was dead. The probit analysis gave the LC50for 24 hours at 0,47%. It can be concluded that ethanol extract of Nigella sativa had an Aedes aegypti larvacide effect.Berbagai jenis tumbuhan berlaku sebagai sumber daya hayati yang penting bagi manusia, karena kandungan bahan aktif dalam tumbuhan tersebut dapat dimanfaatkan diantaranya sebagai insektisida. Jinten hitam (Nigella sativa) adalah salah satu tumbuhan yang relative aman dan tidak berbahaya bagi lingkungan, namun pemanfaatannya untuk pengendalian serangga belum pernah digunakan. Tujuan penelitian ini adalah untuk mengetahui pengaruh ekstrak etanol Nigella sativa terhadap mortalitas larva Aedes aegypti. Pada penelitian ini dilakukan uji mortalitas dengan cara menurut WHO dengan 9 konsentrasi ekstrak Nigella sativa 1%; 0,8%; 0,6%; 0,4%; 0,3%; 0,1%; 0,05%; 0,025% and 0%. mortalitas larva dianalisis menggunakan Anava dan analisis probit untuk menentukan nilai LC50 (24 jam). Hasil penelitian uji mortalitas menunjukkan bahwa ekstrak etanol Nigellasativa semakin tinggi konsentrasi akan semakin tinggi pula kematian larva terutama untuk 24 jam pertama. Pada konsentrasi tertinggi yaitu 1% didapati lebih dari 95% larva mati. Hasil analisis probit diperoleh nilai LC50 dalam 24 jam adalah kadar 0,47%. Dapat disimpulkan bahwa ekstrak etanol Nigella sativa mempunyai efek larvasida pada nyamuk Aedes aegypti.

Pendidikan Dokter Berbasis Kompetensi dan Moralitas dengan Metode Problem Based Learning pada FK UMY Hidayati, Titiek
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 4, No 2 (2004)
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v4i2.1753

To face the coming era, Islamic Revealed Knowledge is really important because of several reasons: (1). Muhammadiyah University has to produce graduates to fulfill the need of 21st century Indonesian Scholar with nation- ally/intemationally qualification; (2). The increase of Islamic society followed by high quality demand reveals the development of Muhammadiyah UniverÂ¬sity as center of human resources development; (3) Islam as the way of live should be apllied in daily activities, especially as a Muslim scholars graduÂ¬ated from Muhammadiyah University; (4). There is no clear definition and principles about Islamic medicine and/or other Islamic revealed knowledge in medical filed.

Black cumin seed oil increase leucocyte and CD4Thelper number in sprague-dawley rats induced with dimethylbenzanthracene Titiek Hidayati; Akrom Akrom; Indrayanti Indrayanti; Sagiran Sagiran
International Journal of Public Health Science (IJPHS) Vol 8, No 2: June 2019
Publisher : Intelektual Pustaka Media Utama

Cigarette smoke contains 7, 12 dimethylbenzanthracene (DMBA). Metabolic of DMBA is immunosuppressive. Black cumin seed oil (BCSO) is an immunomodulation. The aim of this study was to determine the effect of BCSO on leukocyte, CD4Th and CD4CD25Treg in Sprague-Dawley (SD) mice induced with DMBA. The 96 SD rats were divided into 8 groups of 12. Group I received aquabidest and standard feeding. Groups II, III and IV received BCSO (an equivalent of 6.8, 68 and 136 mg/kg BW / day thymoquinone, respectively). Group V received thymoquinone (50 mg / kg BW / day) and group VI received tamoxifen (60 mg / kg BW). Group VII (DMBA) was induced with DMBA (10x20mg / kg BW for 5 weeks). Group VIII received standard feeding and corn oil treatment. In the third week, all groups began to be induced with DMBA (20 mg/kg BW twice per week for five weeks). Data collection of leukocytes, CD4Th and CD4CD25Treg was performed at week 27th. The mean difference of CD4Th and CD4CD25Treg counts between groups was calculated with one way ANOVA. Results: The administration of BCSO, thymoquinone, and tamoxifen had increased leukocytes and CD4 Th cell count. The CD4Th cell count of the treatment groups was higher than that of the DMBA group (p <0.05). BCSO equivalent doses of 6.8 and 68 mg/kg BW / day thymoquinone showed immunoprotective effects. Conclusion: It can be concluded that the BCSO administration at doses of 6.8 and 68 mg/kg BW / day shows immunoprotective effects due to DMBA induction.

Infection and undernutrition increase the risk of stunting among rural children Akrom Akrom; Titiek Hidayati; Olyvia Wulan Kencana; Nurcholid Umam Kurniawan; Prasasti Bintarum
International Journal of Public Health Science (IJPHS) Vol 11, No 3: September 2022
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v11i3.21592

The prevalence of stunting in Indonesia is remaining high. Stunting is found to be more common in rural areas than in urban areas. This study aimed to determine the factors associated with stunting in rural areas. We conducted a case-controlled study in Public Health Center Jetis 1 Yogyakarta, Indonesia. We recruited 80 children with the purposive sampling technique. Data on birth weight and disease history were taken from their medical records. Data on consumption patterns of energy, protein, carbohydrate, and fat were collected through a nutritional survey. Different proportions were tested using the fisher test and the mean difference was tested using an independent t-test. The results showed that child stunting had lower energy and protein consumption levels than non-stunting children (p=0.000). Diarrheal infection, frequency, and duration of illness were more common in stunted than in non-stunted children (p<0.05). Consumption of protein and energy was associated with stunting (p<0.05). This research found differences in the incidence of infection, frequency, length of illness, and hospital stay between stunted and non-stunted children. There is a significant association between the consumption of protein and energy with stunted growth in children in rural public health children.

Benefit of Brown Rice Feeding on Elderly Insomnia Titiek Hidayati; Nevi Seftaviani; Hastin Munifah T.F.F.S.; Ardhitapramesti A.H.P.; Nurisa Fikriyani L.
International Journal of Public Health Science (IJPHS) Vol 4, No 3: September 2015
Publisher : Intelektual Pustaka Media Utama

Difficulty falling asleep or insomnia is one of health problems in elderly. Age is one of the risk factor of insomnia. Tryptophan in brown rice can stimulate the formation of serotonin. Serotonin is a neurotransmitter that causes someone sleeps easily. This research used quasi-experimental design with pretest posttest without control group. Population in this research is 20 elderly persons in Budi Luhur Nursing House unit of Kasihan, Bantul. Result experiment shows that 7 elderly persons have improvement in difficulty falling asleep or insomnia. Improvement of insomnia degree in elderly may be caused by the tryptophan in brown rice. Elderly persons can consume brown rice as alternative food for improving insomnia.

Health education improve behavior and self-efficacy on personal hygiene among children with intellectual disability Titiek Hidayati; Akrom Akrom; Indri Nurasa; Erviana Erviana
International Journal of Public Health Science (IJPHS) Vol 8, No 4: December 2019
Publisher : Intelektual Pustaka Media Utama

Personal hygiene is one of the basic human needs and must be kept clean, including scalp and hair, eyes, nose, ears, nails of hands and feet, skin and overall body care. Health education on personal hygiene is still concern not only for healthy children but also for children with disabilities. One of the ways is with audiovisual methods. This study aimed to analyze the effect of health education on personal hygiene with audiovisual methods. The study design used was pre-experiment without a control group. The number of samples was 30 using total sampling technique. Knowledge of personal hygiene before health education (pre-test) was mostly insufficient category, after being given health education (post-test) mainly was in proper group. The pre-test attitude was in low category, and the post-test was still the same. Pre-test and post-test of behavior were mostly being practiced. Pre-test and post-test of self-efficacy were in low category. There was an influence of health education on personal hygiene with audiovisual methods on the level of knowledge in intellectually disabled children (p<0.05), but there was no effect on attitudes, behaviors, and self-efficacy in intellectually disabled children.

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