Article Per Year (5 Year)
p-Index From 2021 - 2026
6.34
P-Index
This Author published in this journals
All Journal Jurnal Kesehatan Andalas Syntax Literate: Jurnal Ilmiah Indonesia Jurnal Respirologi Indonesia Bioscientia Medicina : Journal of Biomedicine and Translational Research Unri Conference Series: Community Engagement Respiratory Science Bioscientia Medicina : Journal of Biomedicine and Translational Research Co-Value : Jurnal Ekonomi, Koperasi & Kewirausahaan Jurnal Impresi Indonesia Jurnal Ilmu Kesehatan Indonesia (JIKSI) Eduvest - Journal of Universal Studies Detector: Jurnal Inovasi Riset Ilmu Kesehatan Jurnal Sains, Teknologi dan Kesehatan (Medical Scientific Journal) MESINA International Journal of Health and Medicine
Herman, Deddy
Bagian Pulmonologi Dan Kedokteran Respirasi Fakultas Kedokteran Universitas Andalas, Padang 25163, Indonesia
Religion Aerospace Engineering Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

Published : 57 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 57 Documents
Search

 1   2   3   4   5 
Overview of COVID-19 Vaccine Development Strategy Katerine Junaidi; Dewi Wahyu Fitrina; Fenty Anggrainy; Deddy Herman
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 3 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i3.473

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified as the cause of coronavirus disease 20019 (COVID19) pandemic which first emerged in December 2019 in Wuhan city, China. Currently, a vaccine is urgently needed to control the COVID-19 pandemic. Several vaccine candidates are under development and some are in the final stage of clinical trials. The COVID-19 vaccination aims to reduce morbidity and mortality rates, achieve herd immunity to prevent and protect the society, strengthen the health system, maintain productivity and minimize social and economic impacts. Before approval, vaccines have to undergo several clinical trials to ensure its safety profile, efficacy, duration of immune system resistance, and adverse effect. Various strategies have been used in the development of vaccines including viral vector vaccines, nucleic acid vaccines, inactivated virus, live attenuated virus, subunit protein¸and virus-like particle vaccine. Each strategy has its own advantages and disadvantages.
Happy Hypoxemia In COVID-19 Ilham; Deddy Herman; Russilawati
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 5 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i5.514

Abstract

The new coronavirus disease 2019 (COVID-19) pandemic is becoming a global health crisis that challenges health systems around the world. The clinical spectrum of COVID-19 varies from mild upper respiratory tract infections to severe pneumonia and acute respiratory distress syndrome, but there are also many patients present with an SpO2 < 90% but without symptoms of shortness of breath. This phenomenon is called happy hypoxemia or silent hypoxemia. Shortness of breath or dyspnea is a subjective sensation resulting from inadequate breathing effort and is usually described as constriction in the chest, difficulty breathing air or difficulty breathing. Breathing is controlled centrally by the respiratory center in the medulla oblongata and the pons region which controls the "respiratory drive" and adapts respiration to the body's metabolic needs. The mechanisms that play a role in this phenomenon include the presence of intrapulmonary shunts, loss of pulmonary perfusion regulation, vascular microthrombus and impaired pulmonary diffusion capacity.
Layanan Hotline Konsultasi Masalah Kesehatan Pasca COVID-19 Sabrina Ermayanti; Russilawati Russilawati; Fenty Anggraini; Afriani Afriani; Irvan Madison; Oea Khairsyaf; Masrul Basyar; Deddy Herman; Yessy Susanty Sabri; Dewi Wahyu Fitrina; Dessy Mirzati; Elsa Purnama Sari; Dimas Bayu Firdaus
Unri Conference Series: Community Engagement Vol 3 (2021): Seminar Nasional Pemberdayaan Masyarakat
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31258/unricsce.3.296-302

Abstract

Pandemy of Corona virus disease 2019 (Covid-19) has overwhelmed the word for nearly two years. Indonesia is one countries that been hit hard by Covid-19. Even though most of patients with positive test of Covid-19 had no symptoms or mild some of them reported persistent clinical symptoms months after test negative. This population with disorder whose terminology Long Covid-19 need health care to help them cope with this condition. In this need Department of Pulmonology and Respiratory medicine initiate community service activity for Covid-19 survival with Long Covid-19 in the formulation Hotline Service on Post Covid-19 Health Problem. Survivors of Covid-19 who accessed this service originated from variety geographic region in Indonesia. This Activity reached 60 survivors were mostly female (57%), in age group of young adult (62%) and dominant with mild symptoms (58%). Recommendation for these survivors whose mild symptoms was self care observation. There were still about 25 survivors (42%) who need further health care with appropriate speciality.
Hubungan Indeks Massa Tubuh dengan Kadar Albumin pada Pasien Tuberkulosis Paru Farina Angelia; Deddy Herman; Novita Ariani
Jurnal Ilmu Kesehatan Indonesia Vol 1 No 2 (2020): Juli 2020
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1125.935 KB) | DOI: 10.25077/jikesi.v1i2.146

Abstract

Latar Belakang. Tuberkulosis (TB) paru merupakan penyakit infeksi kronis menular yang masih membebani masyarakat Indonesia termasuk Provinsi Sumatera Barat. Interaksi antara infeksi dan status gizi yang buruk merupakan hal kompleks dan saling berkaitan satu sama lain. Status gizi dapat diukur menggunakan Indeks Massa Tubuh (IMT) dan pemeriksaan kadar albumin. Objektif. Mengetahui hubungan antara Indeks Massa Tubuh (IMT) dengan kadar albumin pada pasien TB paru di RSUP dr. M Djamil Padang. Metode. Penelitian ini merupakan penelitian analitik observasional dengan pendekatan cross sectional. Data sekunder diambil dengan menggunakan rekam medik 96 pasien rawat inap TB paru RSUP dr. M. Djamil yang memenuhi kriteria inklusi dan tidak terdapat kriteria eksklusi. Data dipilih melalui purposive sampling. Variabel penelitian ialah IMT dan kadar albumin. Data yang diperoleh dimasukkan ke dalam tabel dan diolah menggunakan program SPSS. Analisis hubungan antar variabel dilakukan dengan uji chi-square. Hasil. Hasil penelitian mendapatkan dari 96 subjek penelitian terdapat 50 orang (52.1%) memiliki IMT kurus, 46 ornag (47.9%) memiliki IMT normal - gemuk. Kadar albumin 96 subjek penelitian terbagi atas 23 orang (24%) memiliki kadar albumin normal, dan 73 orang (76%) memiliki kadar albumin rendah. Hasil analisis uji Pearson Chi-Square antara IMT dengan kadar albumin memiliki nilai p sebesar 0.017 (<0.05). Kesimpulan. Indeks Massa Tubuh (IMT) memiliki hubungan dengan kadar albumin pada pasien TB paru RSUP dr. M. Djamil. Kata kunci: tuberkulosis paru, indeks massa tubuh, kadar albumin. Background. Pulmonary Tuberculosis (TB) is a contagious chronic infectious disease that still burdening the Indonesian people, including in the West Sumatera to the present. The interaction between infection and malnutrition are complex and interrelated. Nutritional status can be measured by calculating Body Mass Index (BMI) and albumin serum levels check. Objective. To determine the relationship between Body Mass Index and albumin levels of pulmonary TB patients in M. Djamil Padang Central Public Hospital. Method. This research was an observational analytic study with a cross-sectional approach. Secondary data retrieval using a medical record of 96 pulmonary TB patients in M. Djamil Hospital that fulfill the inclusion and exclusion criteria. The data were taken using the purposive sampling method. The research variables are Body Mass Index (BMI) and albumin levels. The data obtained is entered into a table and processed using the SPSS program. Variable relationship analysis was performed by using the chi-square test. Result. The result of this study found that from 96 research subjects there were 50 people (52.1%) had an underweight BMI, 46 people (47.9%) had a normal-overweight BMI. On albumin levels, we concluded that 23 people (24%) had normal albumin levels and the remaining 73 people (76%) had low albumin levels. The result of the analysis with the Pearson Chi-Square test between BMI and albumin levels have a p-value of 0.0017 (<0.05). Conclusion. Body Mass Index (BMI) has a relationship with albumin levels of pulmonary TB patients M. Djamil Hospital. Keywords: pulmonary tuberculosis, body mass index, albumin levels.
Perilaku Merokok dan Sikap Mahasiswa Tahun 3 Kedokteran Unand Terkait Program Berhenti Merokok Yasmin Nabila Ramadhani; Deddy Herman; Mefri Yanni
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 4 (2021): Desember 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v2i4.491

Abstract

Latar Belakang: Penggunaan tembakau sampai saat ini masih menjadi ancaman masalah kesehatan paling besar di dunia. Perilaku merokok terdapat pada beberapa kalangan tidak terkecuali tenaga kesehatan dan mahasiswa kedokteran. Tenaga kesehatan pada pelayanan kesehatan sehari-hari diharapkan dapat memberikan konseling kepada pasien untuk berhenti merokok. Objektif: Penelitian ini bertujuan untuk mengetahui perilaku merokok dan sikap mahasiswa tahun 3 pendidikan dokter Universitas Andalas terkait program berhenti merokok berdasarkan Global Health Professions Student Survey (GHPSS). Metode: Penelitian ini merupakan penelitian deskriptif dengan rancangan cross sectional. Penilaian perilaku merokok dan sikap terkait program berhenti merokok dinilai melalui kuesioner GHPSS. Sampel penelitian ini adalah seluruh mahasiswa tahun 3 pendidikan dokter Universitas Andalas. Penelitian ini dilakukan pada Februari 2021 – April 2021. Analisis data pada penelitian ini menggunakan analisis univariat. Hasil: Penelitian ini mendapatkan hanya 4,5% mahasiswa yang merokok, 99,1% berfikir tenaga kesehatan harus memberikan nasihat atau informasi tentang berhenti merokok, dan 61,7% pernah mendapatkan pelatihan formal mengenai pendekatan berhenti merokok untuk digunakan pada pasien. Kesimpulan: Mahasiswa tahun 3 pendidikan dokter Universitas Andalas sebagian besar tidak merokok, seluruh perokok pertama kali merokok di atas 60 menit setelah bangun tidur di pagi hari, dan sebagian besar mendukung kebijakan terkait rokok dan peran tenaga kesehatan pada program berhenti merokok. Mayoritas di antaranya juga menyatakan telah mendapatkan pendidikan/pelatihan mengenai program berhenti merokok.
Asthma as a Protective Factor against COVID-19 Infection: A Narrative Literature Review Monica Bil Geni; Deddy Herman; Dessy Mizarti
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 7 No. 3 (2023): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v7i3.785

Abstract

Asthma and COPD comorbidities are expected to exacerbate the clinical manifestations of COVID-19. However, many reported studies show that asthmatic patients infected with COVID-19 do not show severe clinical manifestations, and some are asymptomatic. This literature review aimed to describe COVID-19 in asthmatic patients along with the hypothesis that asthma is a protective factor against COVID-19 infection. Systemic corticosteroids have been shown to reduce the death/mortality rate in patients who are hospitalized due to COVID-19 infection. This is possibly due to the suppression of the immune system against a hyperinflammatory state which can result in further damage from SARS-CoV-2 infection. Mucus hypersecretion, which is one of the hallmarks of asthma, can prevent the SARS-CoV-2 virus from reaching the distal lung and can protect the lungs from pathological processes. The secreted mucus is rich in glycoproteins, such as MUC5AC, which act as the first line of defense against infection. Mucus hypersecretion in asthmatic patients may prevent SARS-CoV-2 from penetrating far enough to gain access to type-2 alveolar cells, which are the cells that predominantly express ACE2 in the lungs. In conclusion, comorbid asthma in patients infected with COVID-19 does not cause adverse clinical manifestations to appear, but on the contrary, it will have a protective effect on patients.
Asthma as a Protective Factor against COVID-19 Infection: A Narrative Literature Review Monica Bil Geni; Deddy Herman; Dessy Mizarti
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 7 No. 3 (2023): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v7i3.785

Abstract

Asthma and COPD comorbidities are expected to exacerbate the clinical manifestations of COVID-19. However, many reported studies show that asthmatic patients infected with COVID-19 do not show severe clinical manifestations, and some are asymptomatic. This literature review aimed to describe COVID-19 in asthmatic patients along with the hypothesis that asthma is a protective factor against COVID-19 infection. Systemic corticosteroids have been shown to reduce the death/mortality rate in patients who are hospitalized due to COVID-19 infection. This is possibly due to the suppression of the immune system against a hyperinflammatory state which can result in further damage from SARS-CoV-2 infection. Mucus hypersecretion, which is one of the hallmarks of asthma, can prevent the SARS-CoV-2 virus from reaching the distal lung and can protect the lungs from pathological processes. The secreted mucus is rich in glycoproteins, such as MUC5AC, which act as the first line of defense against infection. Mucus hypersecretion in asthmatic patients may prevent SARS-CoV-2 from penetrating far enough to gain access to type-2 alveolar cells, which are the cells that predominantly express ACE2 in the lungs. In conclusion, comorbid asthma in patients infected with COVID-19 does not cause adverse clinical manifestations to appear, but on the contrary, it will have a protective effect on patients.
Profil Pasien COVID-19 dengan Komorbid yang Dirawat di RSUP Dr. M. Djamil Padang Hamni Tanjung; Julizar Julizar; Sabrina Ermayanti; Deddy Herman; Liganda Endo Mahata; Syandrez Prima Putra
Jurnal Ilmu Kesehatan Indonesia Vol 4 No 1 (2023): Maret 2023
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v4i1.971

Abstract

Latar Belakang: Coronavirus Disease 2019 (COVID-19) yang disebabkan Severe Acute Respiratory Coronavirus-2 (SARS-CoV-2) telah menjadi perhatian dunia sejak awal ditemukan hingga saat ini. Keparahan kondisi pasien COVID-19 dengan komorbid dipengaruhi dengan berbagai faktor yang dapat meningkatkan morbiditas dan mortalitas pasien COVID-19. Objektif: Penelitian ini bertujuan untuk mengetahui profil pasien COVID-19 dengan komorbid yang dirawat di RSUP Dr. M. Djamil Padang. Metode: Jenis penelitian ini merupakan observasional deskriptif dengan pendekatan cross-sectional. Data penelitian diambil dari data rekam medis dengan teknik pengambilan total sampling pada pasien yang dirawat pada 1 Oktober sampai 31 Desember 2020. Hasil: Penelitian ini mendapatkan dari total 144 pasien, 34% pasien COVID-19 dengan komorbid merupakan kelompok usia 50-59 tahun, 50,7% berjenis kelamin laki-laki, 59,7% memiliki riwayat pendidikan tingkat menengah dan 53,5% berstatus IMT obesitas. Komorbid terbanyak yang ditemukan adalah 29,2% hipertensi dengan 73,6% pasien memiliki lebih dari satu komorbid, sebanyak 77,1% merupakan COVID-19 derajat sedang dengan 71,5% memiliki lama rawatan 14 hari atau kurang, serta 62,5% memiliki luaran COVID-19 sembuh. Kesimpulan: Penelitian ini menemukan sebagian besar pasien COVID-19 dengan komorbid yang dirawat merupakan kelompok usia tua, dengan komorbid terbanyak hipertensi, sebagian besar memiliki lebih dari satu komorbid, mengalami derajat sakit sedang dengan lama rawatan 14 hari atau kurang, dan luaran sembuh.
LENT Score as a Prognosis Factor for Overall Survival and Progression-Free Survival in Malignant Pleural Effusion Patients at Tertiary Hospitals in West Sumatera, Indonesia Laisa Azka; Sabrina Ermayanti; Russilawati; Irvan Medison; Deddy Herman; Fenty Anggraininy
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 7 No. 6 (2023): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v7i6.835

Abstract

Background: Malignant pleural effusion (MPE) has a variable survival rate and prognosis. The LENT score is one method for assessing survival rates in patients with MPE. This study aimed to investigate the LENT score as a prognostic factor for overall survival (OS) and progression-free survival (PFS) of patients with MPE at a tertiary hospital in West Sumatera. Methods: This study was an observational analytic study involving several tertiary hospitals in West Sumatera with a minimum observation period of 2 years. Data were collected from medical records. We used Kaplan Meier analysis to assess OS and PFS. Results: A total of 198 subjects met the inclusion criteria. Most MPE patients in this study were aged ≥60 years, male, smokers, pleural fluid lactate dehydrogenase value <1500, ECOG 1, serum NLR value <9, and high-risk cancer, namely lung cancer. The distribution of LENT scores for MPE patients was evenly distributed among the low, medium, and high-risk groups. Kaplan Meier analysis showed that the median OS based on LENT scores were 804 days, 275 days, and 161 days, respectively (log-rank test p = 0.000). The median PFS based on LENT scores were 715 days, 202 days, and 106 days, respectively (log-rank test p=0.000). The OS and PFS findings are longer than previous studies. Conclusion: Based on LENT scores, overall survival and progression-free survival MPE patients at tertiary hospitals in West Sumatera have a better prognosis compared to previous studies.
Delayed SARS-COV-2 Viral Clearance in a Newly Diagnosed HIV Patient: A Case Series Dimas Bayu Firdaus; Oea Khairsyaf; Dewi Wahyu; Irvan Medison; Deddy Herman; Masrul Basyar
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 7 No. 6 (2023): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v7i6.836

Abstract

Background: SARS-CoV-2 can infect anyone, but people with HIV have underlying conditions or comorbidities that can make them seriously ill if infected with SARS-CoV-2. HIV attacks and destroys the immune system delays the response of specific antibodies, and even causes failure to thrive, resulting in a long course of the disease. This case report aimed to describe 2 cases of HIV patients co-infected with SARS-CoV-2 with delayed viral clearance. Case presentation: There are two HIV patients with co-infection with SARS-CoV-2. The first patient, a 32-year-old man with COVID-19 and HIV-AIDS, was referred from a regional hospital after being treated for 10 days due to clinical deterioration. Physical examination showed that the patient's general condition was moderately ill, and other vital signs were within normal limits. Oral candidiasis was seen in the patient's mouth, crackles were found in both lung fields, and epigastric tenderness was found on abdominal examination. The patient tested positive for COVID-19 based on the results of an antigen swab examination from the previous hospital. The second patient, a 26-year-old man, came with complaints of intermittent fever 1 week before entering the hospital. Complaints began with the body feeling weak and coughing without phlegm 2 weeks ago. The patient tested positive for COVID-19 based on the results of an antigen swab examination. The delayed viral clearance of SARS-CoV-2 in the two patients was possibly caused by the impaired immune response due to HIV infection, as shown by the presence of lymphopenia and decreased CD4+. Conclusion: ARV use can suppress HIV viral load and increase immunity so that can help viral clearance of SARS-CoV-2.
Co-Authors Abdiana Abdiana, Abdiana Afriani Afriani Ahmad Rafid Almurdi Almurdi Amel Yanis Delmi Sulastri Dessy Mirzati Dessy Mizarti Dessy Mizarti Dessy Mizarti Dewi Wahyu Dewi Wahyu Fitrina Dewi Wahyu Fitrina Dimas Bayu Firdaus Dimas Bayu Firdaus Dwitya Elvira, Dwitya Dzaki Murtadho Efrida Efrida Efrida Elly Usman Elsa Purnama Sari Elsesmita, Elsesmita Ermayanti, Sabrina Ermayanti, Sabrina Eryati Darwin Fadhilah, Dwi Rizki Fadhilla Annisa Efendi Farina Angelia Fathiyyatul Khaira, Fathiyyatul Fenty Anggraini Fenty Anggraininy Fenty Anggrainy Fenty Anggrainy Fitrina, Dewi Wahyu Gustia Rina Habib El Binampiy Busnia Hamni Tanjung Handayani, Friska Hasmiwati Ilham Irvan Madison Irvan Medison Irvan Medison Irvan Medison Irvan Medison Irvan Medison Irvan Medison Irvan Medison Isnaniyah Usman Julizar Julizar Junaidi, Katerine Katerine Junaidi Laisa Azka Mahata, Liganda Endo Malinda Meinapuri Masrul Basyar Masrul Basyar Masrul Basyar Masrul Basyar Masrul Basyar Mefri Yanni Mizarti, Dessy Monica Bil Geni Novita Ariani Nur Indrawaty Lipoeto Nurul Husna Muchtar Oea Khairsyaf Oea Khairsyaf Oea Khairsyaf Povi Pada Indarta Pratama, Fadel Ahmad Rahmadina, Rahmadina Rahmadina, Rahmadina Rizanda Machmud Rizanda Machmud Romaito Nasution Rosfita Rasyid Rosi Maulini Rullian, Harry Pasca Russilawati, Russilawati Sabrina Ermayanti Sari, Popy Puspita Sulastri Sulastri Susanti Sabri4, Yessy Susanti Sabri Syandrez Prima Putra Trisuliandre, Muhammad Rizki Ulfahimayati Ulfahimayati Utami, Sherly Putri Vicennia Serly Yasmin Nabila Ramadhani Yati Ernawati Yessy S Sabri Yessy Susanty Sabri Yessy Susanty Sabri Yulistini, Yulistini Zaki Arbi Ismani