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All Journal Jurnal Kesehatan Andalas Syntax Literate: Jurnal Ilmiah Indonesia Jurnal Respirologi Indonesia Unri Conference Series: Community Engagement Respiratory Science Bioscientia Medicina : Journal of Biomedicine and Translational Research Co-Value : Jurnal Ekonomi, Koperasi & Kewirausahaan Jurnal Impresi Indonesia Jurnal Ilmu Kesehatan Indonesia (JIKSI) Eduvest - Journal of Universal Studies Detector: Jurnal Inovasi Riset Ilmu Kesehatan Sriwijaya Journal of Internal Medicine Jurnal Sains, Teknologi dan Kesehatan (Medical Scientific Journal) MESINA International Journal of Health and Medicine Jurnal Kesehatan
Herman, Deddy
Bagian Pulmonologi Dan Kedokteran Respirasi Fakultas Kedokteran Universitas Andalas, Padang 25163, Indonesia
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Profile of Leprosy Patients at the Dermatology and Venereology Polyclinic of Dr. M. Djamil Padang Hospital in 2018-2021 Habib El Binampiy Busnia; Gustia Rina; Deddy Herman
International Journal of Health and Medicine Vol. 1 No. 4 (2024): October : International Journal of Health and Medicine
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/ijhm.v1i4.96

Abstract

Leprosy is a chronic infectious disease caused by Mycobacterium leprae that attacks several parts of the body, especially the upper respiratory tract, skin, and peripheral nerves. Indonesia is the third country with the most leprosy in the world. This study aims to determine the profile of leprosy patients at the Dermatology and Venereology Polyclinic Dr. M. Djamil Padang Hospital in 2018-2021. This research is descriptive retrospective with total sampling technique using secondary data in the form of medical records. The sample of this study were all leprosy patients in 2018-2021 who were fulfilled inclusion criteria, with a total of 39 patients. The results showed that the most age group was >14 years (100%), the most gender was male (74.36%), the most residence was Padang (33.33%), and almost all leprosy patients (92.31%) had no history of household contact with leprosy patients. Most of the leprosy patients were of the multibacillary type (74.36%) with positive smear results (46.15%), without leprosy reaction (61.54%), and the most disability level that occurred was grade 0 disability (48.72%). The conclusion of this study is that most cases of leprosy at the Dermatology and Venereology Polyclinic RSUP Dr. M. Djamil Padang in 2018-2021 aged >14 years, male, having address in Padang City, had no history household contact, multibacillary type, positive smear result, without reaction, and level 0 disability.
HUBUNGAN KADAR D-DIMER DENGAN DERAJAT KEPARAHAN PENYAKIT DAN ANGKA KEMATIAN PASIEN CORONAVIRUS DISEASE 2019 Trisuliandre, Muhammad Rizki; Herman, Deddy; Yulistini, Yulistini; Efrida, Efrida; Meinapuri, Malinda; Hasmiwati, Hasmiwati
EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan Vol. 2 No. 1 (2025): EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan, Maret 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/empiris.v2i1.973

Abstract

Objective: This study aims to determine the relationship between D-dimer levels and the severity of the disease and the mortality rate of Coronavirus Disease 2019 patients treated at Dr. M. Djamil Padang General Hospital for the period June-August 2021. Method: This type of research is observational analytic using a retrospective cohort study design by taking a sample of 75 people through medical record data. Results: Most of the characteristics of the Coronavirus Disease 2019  patients were found in the age group of 56-65 years, male sex, most of them had an increased D-dimer value, and most of the patients did not die. This study found that there is a relationship between D-dimer levels and the severity of the disease and the mortality rate of Coronavirus Disease 2019 patients. Based on the Odd Ratio value obtained of 2.04 (1.53-2.71), it can be interpreted that people who have D -dimer increases have a risk of dying 2 times. Conclusion: There is a relationship between D-dimer levels and the severity of the disease and the mortality rate of 2019 Coronavirus Disease patients at Dr. M. Djamil Padang for the June-August 2021 period.
Hubungan Kadar Enzim Transaminase Pasien COVID-19 dengan Derajat Keparahan Penyakit di RSUP Dr. M. Djamil Padang Rahmadina, Rahmadina; Herman, Deddy; Efrida, Efrida; Almurdi, Almurdi; Russilawati, Russilawati; Elvira, Dwitya
Jurnal Kesehatan Andalas Vol. 13 No. 1 (2024): March 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v13i1.2205

Abstract

Liver injury can be caused by coronavirus disease 2019 (COVID-19), characterized by increased levels of transaminase enzymes (aspartate aminotransferase/AST and alanine aminotransferase/ALT). Objective: To determined the correlation between transaminase enzyme levels and the severity of COVID-19 in Dr. M. Djamil Central Public Hospital, Padang. Methods: This was an observational analytic study with a cross-sectional design. Data were obtained randomly from medical records of confirmed COVID-19 patients hospitalized in Dr. M. Djamil Hospital from June to August 2021, with moderate, severe, and critical severity based on Indonesian Ministry of Health criteria. Data were analyzed using the Chi-square test to examine the distribution and correlation between variables and a simple logistic regression test to assess the level of risk between variables. Results: 57,80% had abnormal AST, and 44,95% had abnormal ALT. The median AST was highest in the critical group, while the median ALT was highest in the severe group. The distribution of sex and age group were significantly different based on AST and ALT levels, and the distribution of patients with coronary heart disease was significantly different based on ALT levels. Transaminase enzyme levels had a significant correlation with the severity of COVID-19 (p-value = 0,00). Patients with critical degrees had the highest risk for abnormal AST and severe degrees had the highest risk for abnormal ALT. Conclusion: Transaminase enzymes have a significant correlation with the severity of COVID-19.Keywords:  COVID-19, liver injury, transaminases, disease severity
Faktor-Faktor yang Berhubungan dengan Perilaku Merokok Pada Mahasiswa Kedokteran Universitas Andalas Sari, Popy Puspita; Herman, Deddy; Abdiana, Abdiana
Jurnal Ilmu Kesehatan Indonesia Vol. 5 No. 3 (2024): September 2024
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v5i3.1021

Abstract

Abstrak Latar Belakang: Indonesia merupakan negara dengan prevalensi perokok laki-laki tertinggi di Association of Southeast Asian Nations (ASEAN) dan memiliki jumlah perokok terbanyak ketiga di dunia. Prevalensi perokok usia 15 tahun atau lebih di Indonesia terus meningkat setiap tahunnya. Semakin tinggi tingkat pendidikan seseorang, maka ia cenderung tidak merokok. Mahasiswa kedokteran lebih memahami bahaya rokok bagi kesehatan tubuh. Objektif: Penelitian ini bertujuan untuk mengetahui faktor-faktor yang berhubungan dengan perilaku merokok pada mahasiswa kedokteran Universitas Andalas. Metode: Desain penelitian ini adalah cross-sectional. Penelitian ini dilaksanakan di Fakultas Kedokteran Universitas Andalas. Pengumpulan data dilakukan pada bulan Agustus 2020 hingga Desember 2022. Teknik pengambilan sampel adalah total sampling dimana semua populasi menjadi sampel, yaitu 153 orang. Instrumen yang digunakan dalam penelitian ini adalah kuesioner Depression Anxiety Stress Scale (DASS) dan kuesioner Global Youth Tobacco Survey (GYTS), kemudian dianalisis menggunakan uji chi-square. Hasil: Hasil analisis cross tab didapatkan stres (p = 0,250) dan pengaruh orang tua (p = 0,067) memiliki nilai p>0,05, sedangkan pengaruh teman sebaya (p = 0,001) dan iklan rokok (p = 0,016) memiliki nilai p<0,05. Kesimpulan: Faktor-faktor yang berhubungan dengan perilaku merokok, yaitu pengaruh teman sebaya dan iklan rokok, sedangkan stres dan pengaruh orang tua tidak berpengaruh. Kata kunci: perilaku merokok, stres, pengaruh orang tua, pengaruh teman sebaya, iklan rokok
Differences In Interleukin-6 and Liver Enzyme Level Based On Clinical Severity of COVID-19 Patients at Dr. M. Djamil General Hospital, Padang Elsesmita, Elsesmita; Medison, Irvan; Herman, Deddy
Respiratory Science Vol. 5 No. 3 (2025): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v5i3.171

Abstract

Background: COVID-19 pathogenesis involves the release of proinflammatory cytokines and chemokines, known as a "cytokine storm." Interleukin-6 (IL-6) plays a key role in initiating cytokine storms. Cytokine storm causes multiple organ complications. Liver injury affects 14% to 53% of COVID-19 patients and is manifested by increased liver enzymes. This study evaluated differences in IL-6 and liver enzyme levels based on clinical severity in COVID-19 patients. Method: A retrospective cross-sectional study was conducted. COVID-19 patients treated at Dr. M. Djamil General Hospital, Padang, from January 1, 2021, to December 31, 2021, and who met the inclusion and exclusion criteria, were the research subjects. The Kruskal-Wallis test was performed to analyze differences in IL-6, SGOT, and SGPT levels based on clinical severity. Results: Most participants (42.06%) were under 50 years old, half were female (56.15%), obesity was the most common comorbidity (41.39%), and moderate severity was most common (42.06%). The majority of the subjects, 87.47%, had elevated IL-6 levels (≥7 pg/mL). SGOT levels of ≥32 IU/L (46.76%) and SGPT levels of ≥31 IU/L (41.39%) were found in less than half of the subjectsClinical severity was significantly associated with IL-6 levels, resulting in a significant difference in IL-6 levels (P<0.05). The clinical severity of COVID-19 patients at Dr. M. Djamil General Hospital, Padang, resulted in a significant difference in SGOT and SGPT levels (P<0.05). Conclusion: IL-6 levels differed based on clinical severity in COVID-19 patients. SGOT and SGPT levels also differed by clinical severity.
Clinical Characteristics, Outcomes, and Predictors of Severity in Acute Eosinophilic Pneumonia (AEP): A Meta-analysis Zaki Arbi Ismani; Deddy Herman; Fenty Anggrainy
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 7 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i7.1320

Abstract

Background: Acute eosinophilic pneumonia (AEP) is a rare, potentially life-threatening respiratory illness characterized by rapid onset of symptoms, diffuse pulmonary infiltrates, and marked eosinophilia in bronchoalveolar lavage (BAL) fluid. This meta-analysis aimed to synthesize published data to provide robust estimates of clinical characteristics, outcomes, and predictors of severity in patients diagnosed with AEP. Methods: A systematic literature search was conducted in PubMed, Embase, Scopus, and Web of Science databases for studies published between January 1st, 2014, and December 31st, 2024. Inclusion criteria specified observational studies reporting on clinical features, diagnostic findings, and clinical outcomes in patients meeting standard AEP diagnostic criteria. Data extraction and quality assessment (using the Newcastle-Ottawa Scale) were performed independently by two reviewers. Pooled proportions and means were calculated using a random-effects model. Heterogeneity was assessed using the I² statistic. Potential predictors of MV requirement were evaluated by pooling odds ratios (ORs) where available. Results: Six studies met the inclusion criteria, comprising a total of 315 patients diagnosed with AEP. The pooled mean age was 29.5 years (95% CI: 26.8-32.2), with a predominance of male patients (pooled proportion: 78%, 95% CI: 71%-84%, I²=45%). A strong association with recent smoking initiation or change was confirmed (pooled proportion: 85%, 95% CI: 78%-91%, I²=55%). Common presenting symptoms included dyspnea (95%), fever (92%), and cough (88%). While peripheral eosinophilia was variable at presentation (pooled mean: 650 cells/µL, 95% CI: 450-850), BAL eosinophilia was markedly elevated (pooled mean percentage: 42%, 95% CI: 37%-47%, I²=78%). The pooled proportion of patients requiring mechanical ventilation was substantial (38%, 95% CI: 30%-46%, I²=68%). Overall in-hospital mortality remained low (pooled proportion: 1.8%, 95% CI: 0.5%-3.5%, I²=0%). Significant heterogeneity was observed for most pooled estimates. Factors significantly associated with an increased likelihood of requiring mechanical ventilation included a shorter time from symptom onset to presentation (<3 days) (pooled OR: 3.1, 95% CI: 1.8-5.3, I²=35%) and higher initial C-reactive protein (CRP) levels (analyzed descriptively due to varied reporting). Conclusion: This meta-analysis confirms that AEP typically affects young male smokers and presents acutely with severe respiratory symptoms. Despite variable peripheral eosinophilia, marked BAL eosinophilia is a diagnostic hallmark. A significant proportion requires mechanical ventilation, highlighting the potential severity. However, mortality is low with appropriate treatment, typically corticosteroids. Very acute onset and higher inflammatory markers may predict the need for ventilatory support, warranting close monitoring in these patients. Further research with standardized reporting is needed to refine predictors and optimize management strategies.
Faktor-Faktor yang Berhubungan dengan Kepatuhan Berobat Pasien Tuberkulosis Paru di Puskesmas Andalas Utami, Sherly Putri; Machmud, Rizanda; Herman, Deddy; Rasyid, Rosfita; Russilawati, Russilawati; Khaira, Fathiyyatul
MESINA (Medical Scientific Journal) Vol 6, No 1 (2025): Medical Scientific Journal (MESINA)
Publisher : Universitas Muhammadiyah Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32502/msj.v6i1.6390

Abstract

Ketidakpatuhan pasien tuberkulosis dalam pengobatan merupakan penyebab terpenting kegagalan pengobatan dan menjadi hambatan untuk mencapai kesembuhan Tujuan penelitian ini yaitu untuk mengetahui faktor-faktor yang berhubungan dengan kepatuhan berobat pasien tuberkulosis di Puskesmas Andalas. Penelitian ini adalah penelitian analitik observasional dengan rancangan cross sectional. Teknik pengambilan sampel menggunakan total sampling dengan jumlah sampel sebanyak 53 responden. Sampel penelitian adalah pasien tuberkulosis sensitif obat yang berusia diatas 18 tahun dan memiliki kartu TB-01. Pengumpulan data dilakukan dengan wawancara terstruktur menggunakan kuesioner. Analisis data menggunakan uji  Chi-square. Analisis 53 sampel didapatkan sebanyak 43 responden (86,8%) patuh dalam pengobatan, sedangkan sebanyak 7 responden (13,2%) tidak patuh dalam pengobatan TB paru. Hasil penelitian menunjukkan variabel yang berhubungan dengan kepatuhan berobat adalah efek samping obat (p=0,015) dan peran pengawas minum obat (p=0,001), dan variabel yang tidak berhubungan adalah umur (p=0,419), jenis kelamin (p=0,223), tingkat pendidikan (p=0,443), pekerjaan (p=1,000), lama pengobatan (p=0,661) dan jarak rumah (p=0,451). Kesimpulan penelitian ini didapatkan faktor-faktor yang berhubungan dengan kepatuhan berobat pasien TB yaitu, efek samping selama pengobatan dan peran pengawas minum obat
Peranan Kortikosteroid Terhadap Luaran Pasien COVID-19: Sebuah Tinjauan Literatur Ahmad Rafid; Elly Usman; Deddy Herman
Detector: Jurnal Inovasi Riset Ilmu Kesehatan Vol. 2 No. 3 (2024): Agustus : Jurnal Inovasi Riset Ilmu Kesehatan
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/detector.v2i3.4008

Abstract

Corticosteroid is one of the COVID-19 drug agents that has a pros and cons of its use because there has been a research that shows this drug had a negative impact and also there has been a research that recommend its use.This literature study conducted to discuss about role of corticosteroid towards COVID-19 patient’s outcome. This paper is a literature review that evaluates variant journals of original research with clinical study design about role of corticosteroid towards COVID-19 patient's outcome by selecting through electronic database such as PubMed, ScienceDirect, and CENTRAL with designated keywords. There are 16 literatures of clinical study design found through PubMed, ScienceDirect, and CENTRAL. It is know that the role of corticosteroid depend on patient's clinical characteristic and time given to the patients. It can be concluded that corticosteroid had role on improving oxygenation on patients with moderate-critical symptoms, reducing mortality rate on critical patients with hyperinflammation, and reducing the lenght of stay in the hospital.
Hubungan Karakteristik dengan Klasifikasi Kejadian Ikutan pasca Imunisasi COVID-19 pada Tenaga Kesehatan di Kota Padang Fadhilah, Dwi Rizki; Ermayanti, Sabrina; Herman, Deddy
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v9i5.15722

Abstract

Penelitian ini bertujuan untuk meneliti hubungan karakteristik dengan derajat Kejadian Ikutan Pasca Imunisasi (KIPI) COVID-19 pada tenaga kesehatan di Rumah Sakit Umum Se-Kota Padang. Metode penelitian ini adalah retrospektif cohort. Hasil penelitian menunjukkan bahwa kejadian terbanyak adalah reaksi lokal yaitu nyeri pada lokasi suntikan, yang terjadi pada 98% dosis pertama dan 95,3% dosis kedua. Reaksi sistemik terbanyak adalah kelelahan yang dialami oleh 49,8% pada dosis pertama dan 45,9% pada dosis kedua. Umur terbanyak yang mengalami KIPI berkisar 26-35 tahun, dan jenis kelamin yang paling banyak mengalami KIPI adalah perempuan. Tidak ada hubungan signifikansi antara karakteristik dengan klasifikasi KIPI COVID-19 pada tenaga kesehatan di rumah sakit umum se-Kota Padang. Penelitian ini menuturkan bahwa reaksi lokal adalah kejadian terbanyak dan tidak ada hubungan signifikansi antara karakteristik dengan derajat KIPI COVID-19.
Association Between the Severity of Chronic Obstructive Pulmonary Disease and the Probability of Pulmonary Hypertension In a Tertiary Hospital Handayani, Friska; Herman, Deddy; Fitrina, Dewi Wahyu
Jurnal Respirologi Indonesia Vol 45 No 2 (2025)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v45i2.873

Abstract

Background: Chronic obstructive pulmonary disease (COPD) patients with pulmonary hypertension (PH) have a poor prognosis, which worries doctors. The prevalence of COPD-related PH is unclear. The lack of anatomical criteria for right ventricular hypertrophy may explain research variance. Only type 1 PH patients undergo direct right cardiac catheterization of pulmonary artery pressure. Methods: A cross-sectional analytical descriptive study examined stable COPD patients visiting the pulmonary department at M. Djamil Hospital, Padang, from November 2023 to February 2024 for PH probability. Results: This study included 64 participants, with a majority aged between 40 and 65 years (59.4%), a significant proportion male (82.8%), and a junior high school (29.7%) level of education. Most of the subjects smoked (81.2%), had severe Brinkman Index (75.0%), had severe GOLD criteria (50.0%), and had no comorbidities (53.1%). No correlation was found between the severity of COPD and the likelihood of PH (P=0.591). The Brinkman Index of smokers was a significant risk factor for PH (P=0.010; OR=1.282; 95% CI=0.260-6.315).  Conclusion: There is no significant association between the severity of COPD according to GOLD criteria and the likelihood of PH.
Co-Authors Abdiana Abdiana, Abdiana Afriani Sandra Ahmad Rafid Almurdi Almurdi Amel Yanis Delmi Sulastri Dessy Mirzati Dessy Mizarti Dessy Mizarti Dessy Mizarti Dessy Mizarti Dewi Wahyu Dewi Wahyu Fitrina Dewi Wahyu Fitrina Dewi Wahyu Fitrina Dimas Bayu Firdaus Dimas Bayu Firdaus Dwitya Elvira, Dwitya Dzaki Murtadho Dzaki Murtadho Efrida Efrida Elly Usman Elsa Purnama Sari Elsesmita, Elsesmita Ermayanti, Sabrina Ermayanti, Sabrina Eryati Darwin Fadel Ahmad Pratama Fadhilah, Dwi Rizki Fadhilla Annisa Efendi Farina Angelia Fathiyyatul Khaira, Fathiyyatul Fenty Anggraini Fenty Anggraininy Fenty Anggrainy Fenty Anggrainy Fitrina, Dewi Wahyu Habib El Binampiy Busnia Hamni Tanjung Handayani, Friska Hasmiwati Herry Saputra Yunior Ilham Irvan Madison Irvan Medison Irvan Medison Irvan Medison Irvan Medison Irvan Medison Irvan Medison Irvan Medison Isnaniyah Usman Julizar Julizar Junaidi, Katerine Katerine Junaidi Laisa Azka Mahata, Liganda Endo Malinda Meinapuri Masrul Basyar Masrul Basyar Masrul Basyar Masrul Basyar Masrul Basyar Masrul Basyar Masrul Basyar Monica Bil Geni Novita Ariani Nur Indrawaty Lipoeto Nurul Husna Muchtar Oea Khairsyaf Oea Khairsyaf Oea Khairsyaf Povi Pada Indarta Rahmadina, Rahmadina Rahmadina, Rahmadina Ricky Permata Irzal Rina Gustia Rizanda Machmud Rizanda Machmud Romaito Nasution Rosfita Rasyid Rosi Maulini Rullian, Harry Pasca Russilawati Russilawati Russilawati, Russilawati Sabrina Ermayanti Sari, Popy Puspita Sulastri Sulastri Susanti Sabri4, Yessy Susanti Sabri Syandrez Prima Putra Trisuliandre, Muhammad Rizki Ulfahimayati Ulfahimayati Utami, Sherly Putri Vicennia Serly Vicennia Serly Yanni, Mefri Yasmin Nabila Ramadhani Yati Ernawati Yessy S Sabri Yessy Susanty Sabri Yulistini, Yulistini Zaki Arbi Ismani