Claim Missing Document
Check
Articles

Perbandingan Kadar Kalium Packed Red Cell Berdasarkan Lama Penyimpanan Di Bank Darah RSUP Dr. M. Djamil Padang Tuti Asryani; Rismawati Yaswir; Zelly Dia Rofinda
Jurnal Kesehatan Andalas Vol 7 (2018): Supplement 3
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v7i0.862

Abstract

Packed Red Cell (PRC) adalah komponen darah yang didapat setelah sebagian besar plasma dipisahkan dari whole blood dengan berbagai metode dan memiliki nilai hematokrit sebesar 80%. Packed Red Cell disimpan pada suhu 2-6 °C selama 21-42 hari tergantung larutan antikoagulan-pengawet yang digunakan. Aktivitas pompa Na+/K+ATPase sangat dipengaruhi oleh suhu. Pompa menjadi inaktif pada suhu 4 °C menyebabkan kebocoran kalium ke plasma akibat kegagalan pompa Na+/K+ATPase, proses ini terjadi perlahan dan terus menerus sehingga kadar kalium pada plasma PRC meningkat seiring dengan bertambahnya waktu penyimpanan. Hiperkalemia merupakan komplikasi tersering transfusi darah simpan. Tujuan penelitian ini adalah mengetahui perbedaan kadar kalium PRC pada penyimpanan 4-14 hari dan > 14 hari di Bank Darah RSUP dr.M.Djamil Padang. Penelitian ini adalah suatu penelitian analitik dengan rancangan potong lintang. Penelitian ini dimulai bulan September 2016 sampai Agustus 2017. Kadar kalium diperiksa dengan metode ion selective electrode indirect (ISE indirect). Analisis data menggunakan uji t, bermakna bila p<0,005. Rerata kadar kalium pada penyimpanan 4-14 hari 3,9 (0,8) mmol/L dan penyimpanan >14 hari 8,7 (4,9) mmol/L. Terdapat perbedaan bermakna rerata kadar kalium PRC berdasarkan lama penyimpanan menggunakan uji t dengan rerata kadar kalium tertinggi pada penyimpanan > 14 hari (p = 0,000).  Terdapat perbedaan bermakna kadar kalium PRC berdasarkan lama penyimpanan dengan rerata kadar kalium PRC lebih tinggi pada penyimpanan > 14 hari.
Pengaruh Vitamin C terhadap Waktu Perdarahan Mencit yang Dipapar Asap Rokok Alles Firmansyah; Zelly Dia Rofinda; Erkadius Erkadius
Jurnal Kesehatan Andalas Vol 6, No 3 (2017)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v6i3.725

Abstract

Asap rokok diketahui meningkatkan Reactive Oxygen Species (ROS). ROS dapat merusak pembuluh darah dan mengubah reaktivitas trombosit sehingga mengganggu sistem hemostasis. Vitamin C sebagai antioksidan esensial bagi tubuh terbukti dapat mengurangi kerusakan oksidatif akibat ROS. Tujuan penelitian ini adalah membuktikan potensi vitamin C dalam menghambat gangguan hemostasis melalui pengamatan waktu perdarahan mencit yang dipapar asap rokok. Penelitian Randomized Pre Test-Post Test Control Group Design ini dilakukan pada 21 ekor mencit jantan yang dibagi menjadi tiga kelompok. Pemberian perlakuan pada hari ke-1 hingga ke-14, yaitu P1 (kontrol negatif), P2 (paparan asap rokok 10 menit perhari), dan P3 (vitamin C 0,4 mg/gBB/hari + paparan asap rokok 10 menit perhari). Pengukuran waktu perdarahan metode tail bleeding pada hari ke-0 dan ke-15. Analisis data menggunakan uji t-paired, one-way Anova, dan post-hoc LSD. Hasil penelitian menunjukkan rerata waktu perdarahan P1 mengalami perubahan yang tidak bermakna dari 60,16 ± 3,27 menjadi 57,61 ± 4,88 detik. P2 mengalami perubahan yang bermakna dari 59,34 ± 6,93 menjadi 38,85 ± 3,43 detik. P3 mengalami perubahan yang bermaknadari 59,36 ± 3,07 menjadi 51.85 ± 3,45 detik. Terdapat perbedaan rerata waktu perdarahan setelah perlakuan yang bermakna signifikan (p = 0,000) antara P2 dengan P3. Penelitian ini berhasil membuktikan potensi vitamin C dalam mencegah pemendekan waktu perdarahan lebih lanjut sebagai indikator gangguan hemostasis akibat paparan asap rokok.
Korelasi Kadar Adiponektin dengan Kadar Kolesterol High Density Lipoprotein pada Penyandang Obes Fiona Septi Mulya; Efrida Efrida; Zelly Dia Rofinda
Jurnal Kesehatan Andalas Vol 10, No 3 (2021): Online November 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v10i3.1716

Abstract

Adiponectin and HDL cholesterol have a protective cardiovascular effect. Adiponectin levels decrease in obese people. This causes ATP-binding cassette transporter A1 expression and apolipoprotein A-I synthesis in hepatocytes to decrease, resulting in impaired HDL cholesterol synthesis. Objectives: To determined the correlation between adiponectin levels with HDL cholesterol levels in obese. Methods: This was the analytic study with a cross-sectional design of 59 obese people who met inclusion and exclusion criteria at RSUP dr. M. Djamil Padang, from January to August 2019. Research subjects were grouped into two groups based on WHO Asia Pacific body mass index (BMI) classification. First-degree obesity group (25.0 £ BMI <30.0 kg/m2) and second-degree obesity group (BMI ≥ 30.0kg/ m2). Adiponectin levels were examined by the enzyme-linked immunosorbent assay (ELISA) method and HDL cholesterol levels by the enzymatic colorimetric method. Data analyzed by Pearson correlation test, significant if p <0.05. Results: Research subjects 59 people (17 men, 42 women), average age 35 (8.04) years. Adiponectin levels in the first-degree obesity group were higher than second-degree obesity group, with a mean difference between groups 1.03 μg/mL (CI: 95%: 0.14 - 1.92, p = 0.02). Results showed adiponectin levels positively correlated with HDL cholesterol levels of moderate strength (r = 0.45) and statistically significant (p = <0.001). The results of the population subanalysis show relatively similar patterns. First-degree obesity population (r = 0.55; p = 0.002), second-degree obesity population (r = 0.41; p = 0.026). Conclusions: Adiponectin levels correlate with HDL cholesterol levels.Keywords: adiponectin, HDL cholesterol, obesity
Hubungan Kadar Gula Darah saat Masuk Rumah Sakit dengan Jenis Sindroma Koroner Akut di RS Dr. M. Djamil Padang Willy Valerian; Masrul Syafri; Zelly Dia Rofinda
Jurnal Kesehatan Andalas Vol 4, No 2 (2015)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v4i2.267

Abstract

AbstrakSindrom Koroner Akut (SKA) merupakan spektrum dari penyakit arteri koroner yang tidak stabil, mulai dari angina pektoris tidak stabil sampai infark miokardium. SKA terbagi atas Unstable Angina Pectoris (UAP), ST elevation myocardial infarction (STEMI), Non-ST elevation myocardial infarction (NSTEMI). Tujuan penelitian ini adalah untuk menentukan hubungan antara kadar gula darah saat masuk rumah sakit dan jenis SKA. Metode penelitian yang digunakan adalah cross sectional. Penelitian dilakukan di Instalasi Rekam Medik RS Dr. M. Djamil Padang dengan mengambil data pasien SKA dari Januari 2012 sampai Desember 2012. Hasil penelitian ini didapatkan jenis SKA dengan gula darah yang tidak normal dari 60 sampel, yaitu: UAP 25%, NSTEMI 35%, STEMI 40%. Hasil pengolahan data dapat dilihat bahwa nilai p = 0,592 yang artinya tidak terdapat hubungan yang bermakna antara kadar gula darah saat masuk rumah sakit dengan jenis SKA. Hal ini terjadi mungkin karena terlalu sedikitnya sampel dan banyak sampel kriteria ekslusi dalam pencarian data. Sebaiknya dalam penelitian yang akan datang dapat memperbanyak sampel.Kata kunci: sindrom koroner akut, kadar gula darah, hubungan kadar gula darah dengan SKA AbstractAcute Coronary Syndrome (ACS) is a spectrum of coronary artery disease that is not stable, ranging from unstable angina to myocardial infarction. Acute Coronary Syndrome is divided into Unstable Angina Pectoris (UAP), ST elevation myocardial infarction (STEMI), non-ST elevation myocardial infarction (NSTEMI). The objective of this study was to determine the relationship between blood sugar levels when admitted to hospital and Acute Coronary Syndrome type by using cross sectional study. The study was conducted at the Medical Records RS Dr. M. Djamil Padang. The ACS data collected from January 2012 until December 2012. The results of this study was found the SKA with abnormal blood sugar of 60 samples, i.e. UAP25%, NSTEMI35%, 40% STEMI. On the results of data processing can be seen that the value of p=0.592, which means there is no significant correlation between blood sugar levels upon hospital admission and the type of SKA. No relationship because of little samples and exclusion criteria. The further study has to used more samples.Keywords: acute coronary syndrome, blood sugar levels, blood sugar relationship with acute coronary syndrome
Karakteristik Pasien Transfusi Darah dengan Inkompatibilitas Crossmatch di UTD RSUP DR. M. Djamil Padang Desta Purwati; Zelly Dia Rofinda; Husni Husni
Jurnal Kesehatan Andalas Vol 9, No 3 (2020): Online September 2020
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v9i3.1328

Abstract

Transfusi adalah pelayanan  kesehatan  yang bagaikan pisau bermata dua. Disatu sisi terkadang merupakan satu-satunya cara penyelamatan pasien, tetapi disisi lain transfusi juga berisiko fatal. Transfusi yang aman dapat diperoleh dengan melakukan uji kompatibilitas diantaranya crossmatch. Inkompatibilitas pada crossmatch dipengaruhi banyak faktor. Tujuan: Menyajikan data karakteristik pasien transfusi darah dengan inkompatibilitas crossmatch di UTD RSUP DR.M.Djamil Padang Periode Juli-Desember 2018. Metode: Penelitian ini adalah  penelitian deskriptif.  Hasil pemeriksaan dengan inkompatibilitas crossmatch  dikumpulkan dan dilihat karakteristik pasien berupa jenis kelamin, umur,, golongan darah, diagnosis, tipe inkompatibilitas dan riwayat transfusi. Hasil: Inkompatibilitas terbanyak didapatkan pada perempuan (61,6%), usia >50 tahun (54,36%), golongan darah A(37,86%), diagnosis infeksi (26,21%), tipe inkompatibilitas minor (87,3%) dan dengan riwayat transfusi berulang  (58,25%). Simpulan: Inkompatibilitas crossmatch tidak dipengaruhi jenis kelamin tetapi dipengaruhi riwayat transfusi sebelumnya.Kata kunci: inkompatibilitas crossmatch, karakteristik pasien, transfusi darah
IDENTIFIKASI MASALAH DAN PENYULUHAN KESEHATAN PADA LANJUT USIA DI NAGARI SUMANIAK Aisyah Elliyanti; Dian Pertiwi; Arina Widya Murni; Zelly Dia Rofinda; Yulistini Yulistini; Afriwardi Afriwardi; Eti Yerizel; Siti Nurhajjah; Elmatris Sy; Elizabeth Bahar
Jurnal Hilirisasi IPTEKS Vol 2 No 1 (2019)
Publisher : LPPM Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (621.872 KB) | DOI: 10.25077/jhi.v2i1.354

Abstract

Pelayanan kesehatan terhadap lanjut usia (lansia) perlu mendapatkan perhatian khusus, karena lansia rentan terhadap penyakit Tujuan: Pengabdian masyarakat ini dilakukan dengan tujuan untuk mengidentifikasi faktor risiko penyakit dan memberikan penyuluhan pada kelompok lanjut usia di Kenagarian Sumanik. Metode: Kegiatan yang dilakukan adalah pemeriksaan kesehatan lanjut usia dan pengkajian psikologis dengan menggunakan kuisioner DASS 42. Selanjutnya dilakukan penyuluhan kesehatan dengan harapan meningkatkan pengetahuan para lansia sehingga mampu mengidentifikasi tanda bahaya dan mendapat pertolongan lebih awal. Hasil: Kegiatan dihadiri oleh 63 orang warga, 31 orang diantaranya di atas usia 60 tahun. Hasil pemeriksaan ditemukan 22 orang mengalami hipertensi stadium 2, dan 5 orang menderita diabetes yang sebelumnya sudah diketahui akan tetapi kontrol tidak teratur. Pada pemeriksaan mata terdapat 25 orang menderita gangguan refraksi, 5 orang ekstensi lensa dan dirujuk ke RSUD melalui Puskesmas. Dari kajian psikologis didapatkan 5 orang memiliki gejala depresi, 15 orang dengan ansietas dan 48 orang mengalami stress-psikologis. Kesimpulan: Penyuluhan kesehatan sangat diperlukan terutama kelompok lanjut usia supaya lansia dapat mengenal tanda-tanda penyakit sehingga dapat pelayanan kesehatan lebih dini. Aktivitas fisik seperti berolahraga diperlukan namun lansia perlu mengetahui jenis olah raga yang tepat sesuai dengan usia.
PEMERIKSAAN DAN PENGOBATAN MATA DAN KULIT PADA KELOMPOK LANSIA DI NAGARI SUMANIAK Aisyah Elliyanti; Dian Pertiwi; Arina Widya Murni; Rina Gustia; Hendriati Hendriati; Zelly Dia Rofinda; Yulistini Yulistini; Afriwardi Afriwardi; Elmatris Sy
BULETIN ILMIAH NAGARI MEMBANGUN Vol 2 No 1 (2019)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v2i1.97

Abstract

Health services for the elderly need to get special attention, because they are vulnerable for suffering from disease and tend to experience multi-pathology. Some of the health problems of the elderly in Kenagarian Sumaniak had been identified in community service activities before. Aim: The activity aims is to conduct examination and treatment of eye and skin disorders, as also to conduct counseling on the elderly. Methods: The activity is ayes and skin examination and treatment for elderly people in Kenagarian Sumaniak. Furthermore, counseling was also given regarding physical fitness and maintenance of skin health in the elderly. Results: The event was attended by 70 people aged 52-82 years, 28 men and 52 women. The results of the examination found 64 people suffering from eye disorders with diagnoses were dry eyes 24person, immature cataract 16 person and pterygium14 person. Around 52 people suffering from skin disorders with diagnoses were dermatitis 28 person such as dermatitis allergy, numularis, intertriginosa, sebaroid, and chronic). Conclusions: Health problems in the eyes and skin of the elderly identified are mostly overcome with the medicines provided. Some of them are recommended to go to primary health care to get further health services.
PEMERIKSAAN BUTA WARNA, GOLONGAN DARAH DAN KADAR HEMOGLOBIN PADA ANAK USIA SEKOLAH DI NAGARI SUMANIAK Aisyah Elliyanti; Dian Pertiwi; Arina Widya Murni; Zelly Dia Rofinda; Hendriati Hendriati; Julizar Julizar; Rahmat Syawqi; Husnil Wardiyah
BULETIN ILMIAH NAGARI MEMBANGUN Vol 3 No 2 (2020)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v3i2.199

Abstract

The growth and development of children disturbance is a health problem that often is found in the community. Anemia and colour blindness are also health conditions that can affect the quality of growth and development of children, which parents rarely realize. The blood type of children is seldom defined in early ages by the parents. This activity aims to conduct health counselling, the examination of colour blindness, blood type, and hemoglobin levels in school-age children in Sumanik village. Methods: Activities were health education on how to wash hands properly and be aware of internet content. The activities were continued by a health examination, such as examining colour blindness, hemoglobin levels, and blood type. Testing of blood type on 76 children, two of 79 children has partial colour blindness. We found From 28 children (36.4%) having anemia, with hemoglobin levels 9.2-11.9 gr / dL, and one child has a blood type B rhesus (-). From this activity, it can be concluded that the low level of knowledge of school-age children in Kenagarian Sumaniak about how to wash hands properly and correctly, even children do not know the adverse effects associated with adult content on the internet. In addition, it appears that children with anemia are still relatively high. For this reason, continuous health promotion is needed. For disorders that can not be overcome at the time of activity, it is recommended to get treatment to the nearest health care centre.
EDUKASI DAN PEMERIKSAAN KESEHATAN MASYARAKAT DI KAMPUNG BATU BUSUK KECAMATAN PAUH KOTA PADANG Saptino Miro; Najirman Najirman; Dinda Aprillia; Fauzar Fauzar; Andry Kurniawan; Zelly Dia Rofinda
BULETIN ILMIAH NAGARI MEMBANGUN Vol 5 No 1 (2022)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v5i1.391

Abstract

Non-contagious diseases have continued to increase over the years. In 2016, about 71 percent of the world's causes of death were non-contagious diseases (NCD) that kill 36 million people annually. Major risk factors of the non-contagious disease are metabolic factors, behavioral factors, and environmental factors. Riskesdas 2018 shows the prevalence of non-contagious diseases increasing compared with Riskesdas 2013, including cancer, stroke, chronic kidney disease, diabetes mellitus, and hypertension. The purpose of this activity is to increase promotive and preventive effort and education in the community, as well as improved screening and early detection through health education, blood pressure, blood sugar, cholesterol levels, and the abdominal ultrasound of society in Kampung Batu Busuk, Kelurahan Limau Manis, Kecamatan Pauh, Padang on Saturday, November 13th, 2021. Such activities include medical examinations of blood pressure, cholesterol, blood sugar, and abdominal ultrasound. From the activity of the examination of the health of 41 persons, 13 were hypertensive, 2 (32%) were hyperglycemia, 24 (58.5 percent) were dyslipidemia, and 6 were fatty liver. To counter the problem of non-contagious diseases, comprehensive and holistic intervention efforts must be made, that is, promotive, preventive, curative, and rehabilitative, as a unified continum of care. Disorders that are not treatable during an activity are recommended for treatment at a nearby health care center.
CORRELATION OF FREE HEMOGLOBIN LEVEL AND PLASMA NITRIC OXIDE IN PACKED RED CELL DURING BLOOD BANK STORAGE PERIOD Ricca Fitria; Zelly Dia Rofinda; Desywar Desywar
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 25, No 1 (2018)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v25i1.1485

Abstract

Stored red blood cells undergo morphological and biochemical changes with increased storage time, commonly refferred as the storage lesion, reduced integrity of erythrocyte membrane, causing hemolysis and increased free plasma hemoglobin level. Nitric Oxide (NO) is an endogenous vasodilator with the major role in vascular and blood flow regulation. Accumulation of free hemoglobin (fHb) during storage RBC hemolysis is thought to be correlated with elevated NO consuming causes low NO level that significantly impair endothelial function. This study aim to was to analyze the correlation of free Hb and plasma nitric oxide level during PRC storage period in the blood bank. This research was an analytic study with a cross-sectional design to 14 unit PRC those were stored in Dr. M. Djamil Padang Hospital Blood Bank. The study was conducted from May 2016 to August 2017. The assay was performed for 28 days of storage with one week intervals. Free plasma hemoglobin and NO level were analyzed by cyanmethemoglobin and colorimetry method respectively. Spearman test was used to access the correlation between free Hb level and nitric oxide plasma with p<0.05 means significant.  Most donors were male (85.7%) with age range were 33(9) years. Free Hb and nitric oxide level were significantly differenced in each week storage periods (p<0.05). Two parameters was significantly had moderate negative correlation during storage periods (r=-0.56; p=0.01).
Co-Authors Adelin, Prima Afriwardi Afriwardi Aisah Aisah Aisyah Elliyanti Aisyah Ellyanti Aldian Mulyanto Lokaria Aldian Mulyanto Lokaria Alles Firmansyah Almurdi Almurdi Alqadri Alqadri Alvarino Amanda Rizki Ami Tri Nursasmi Andry Kurniawan Andry Kurniawan Antonius, Puja Agung Arina Widya Murni Ashal, Taufik Asterina Asterina Aswiyanti Asri Berliana Islamiyarti Hydra Berliana Islamiyarti Hydra Bobby Indra Utama Daan Khambri Daulat Azhari Dessy Arisanti Desta Purwati Desywar Desywar Desywar Desywar Desywar Dian Jenova Dian Pertiwi Dian Pertiwi Dinda Aprillia Dinda Aprillia Dwi Yulia Edison Edison Efrida Efrida Efrida Elizabeth Bahar Ellyza Nasrul Elmatris Sy Elvinawaty Elvinawaty Endrinaldi Endrinaldi Endrinaldi Erkadius Erkadius Eti Yerizel Etriyel Myh Fadil Oenzil Fauzan Arisyi Koto Fauzar Fauzar Fauzar Fauzar Febby Genta Wahyuni Febrita Joniarti Feby Febriatama Fiona Septi Mulya Firdawati Firdawati Gusti Revilla Hanifah Maani Hanifah Maani Hasmiwati Hendriati, Hendriati Hevrina Yufani Hevrina Yufani Husna Yetti Husni Husni Husni Husni Husni Husni Husnil Kadri Husnil Wardiyah Ira Ferawati Julizar Julizar Julizar Julizar M. Ikhlasul Amal Eel Taslim Masrul Masrul Syafri Mohamad Reza Najirman Najirman Nanda Oktavia Nur Izzah Atirah Hardinur Putri Auliya Putri, Biomechy Oktomalio Rahmat Syawqi Rahmat Syawqi Rama Dhanivita Djamin Rani Novelty Rauza Sukma Rita Ricca Fitria Rika Susanti Rikarni Rikarni Rina Gustia Risma Isti Rismawati Yaswir Rizanda Machmud Rizki Rahmadian Rosfita Rasyid Rulli Firmansyah Salsabila Dhiyaa Syifa Saptino Miro Sharon Serafim Bosawer Siti Nurhajjah Sri Widyaningsih Suswita, Rini Tuti Asryani Verbrini Rifnayeni Willy Valerian Wirsma Arif Yashinta Octavian Gita Setyanda Yulistini, Yulistini Yusrawati Yusrawati Yustini Alioes