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All Journal Jurnal Kesehatan Andalas Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Jurnal Hilirisasi IPTEKS (JHI) Buletin Ilmiah Nagari Membangun Majalah Kedokteran Andalas Bioscientia Medicina : Journal of Biomedicine and Translational Research Health and Medical Journal Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Ilmu Kesehatan Indonesia (JIKSI) JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia
Dia Rofinda, Zelly Dia
Bagian Patologi Klinik Fakultas Kedokteran Universitas Andalas
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Karakteristik Penderita Tumor Mediastinum di RSUP Dr. M. Djamil, Padang periode 2015-2019 Nur Izzah Atirah Hardinur; Aisyah Ellyanti; Zelly Dia Rofinda
Jurnal Ilmu Kesehatan Indonesia Vol 1 No 2 (2020): Juli 2020
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1000.916 KB) | DOI: 10.25077/jikesi.v1i2.93

Abstract

Tumor mediastinum merupakan salah satu kelainan di rongga mediastinum dengan berbagai spektrum klinis dan jenis histopatologi. Di Indonesia masih sedikit penelitian dan literatur mengenai tumor mediastinum. Khususnya di Padang, masih kekurangan karakteristik epidemiologi, klinis, dan karakteristik histopatologi dari tumor mediastinum. Penelitian ini bertujuan untuk mengetahui karakteristik dari tumor mediastinum di RSUP Dr. M. DJamil Padang. Penelitian ini merupakan penelitian deskriptif observasional dengan desain cross sectional. Data penelitian didapatkan dari rekam medis yang memenuhi kriteria sampel periode 2015 – 2019. Kriteria inklusi dari penelitian ini adalah seluruh rekam medis pasien dengan diagnosis klinis tumor mediastinum, dan kriteria eksklusinya adalah tidak lengkap umur dan jenis kelamin pasien, status merokok, lokasi tumor, gambaran klinis, serta jenis histopatologi tumor. Hasil penelitian dikelompokkan dalam tabel distribusi frekuensi. Hasil penelitian didapatkan 40 sampel yang memenuhi kriteria inklusi. Pasien tumor mediastinum kebanyakan berusia 51-60 tahun (27,5%), berjenis kelamin laki-laki (55%) dan hampir separuh pasien memiliki riwayat merokok (47,5%). Lokasi massa terbanyak pada kompartemen anterior. Pasien umumnya datang dengan keluhan sesak napas (82,5%), diikuti oleh batuk, nyeri dada dan penurunan berat badan. Jenis tumor mediastinum yang paling sering terjadi adalah tumor timus (42,5%). Kematian saat perawatan di rumah sakit mencapai 7,5%. Kesimpulan pada penelitian ini adalah tumor mediastinum lebih banyak terjadi pada pasien di atas umur 51 tahun, berjenis kelamin laki-laki, dengan tumor timus sebagai jenis histopatologi yang paling umum. Kata kunci : karakteristik; tumor mediastinum; mediastinum.
Profil Penderita Anemia Aplastik di RSUP Dr. M. Djamil Padang Tahun 2018-2019 Amanda Rizki; Zelly Dia Rofinda; Gusti Revilla
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 1 (2021): Maret 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1170.255 KB) | DOI: 10.25077/jikesi.v2i1.274

Abstract

Background. Aplastic anemia is a failure of the process of formation and development of blood cells that causes a decrease or absence of hematopoietic precursor cells in the bone marrow. Although the prevalence of this disease is rare, aplastic anemia has the potential to cause death with risk factors that are easily found in everyday life and are rarely realized.Objective. To determine the profile of patients with aplastic anemia at General Hospital Dr M Djamil Padang.Methods. This is a descriptive retrospective study. The population of this study are all patients diagnosed with aplastic anemia by clinicians in the Medical Record Installation of Dr. M. Djamil Hospital, Padang, between 1 January 2018 - 31 December 2019..Results The results showed that 21.57% patients with aplastic anemia were at the age of 56-65 years and the incidence was higher in women than men. The highest risk factor was exposure to chemical and insecticides (18.62%), but 54.9% of the data did not include risk factors. 31.37% work as students. 67.65% suffered from mild aplastic anemia, 60.78% were on immunosuppressive therapy, and 65.69% had partial remission outcomes.Conclusion. The majority of patients with aplastic anemia based on age are 56-65 years and based on gender, the incidence is higher in women. The most common risk factors were exposure to chemical and insecticides. . The most common level of severity is non-severe aplastic anemia. The most common type of therapy is immunosuppressive therapy. The most common outcome is partial remission.
Korelasi Kadar Vitamin D dengan Indeks Aterogenik Plasma pada Mahasiswa Penyandang Obesitas M. Ikhlasul Amal Eel Taslim; Zelly Dia Rofinda; Rismawati Yaswir
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 4 (2021): Desember 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v2i4.521

Abstract

Latar Belakang: Defisiensi vitamin D telah menjadi masalah kesehatan dunia dan berkembang pesat selama beberapa tahun terakhir ini. Defisiensi vitamin D merupakan salah satu faktor risiko penyakit kardiovaskular. Indeks aterogenik plasma yang dirumuskan sebagai log10(TG/HDL) merupakan penanda aterogenesitas untuk memperkirakan risiko penyakit kardiovaskular. Defisiensi vitamin D dan nilai indeks aterogenik plasma yang tinggi sering ditemukan pada penyandang obes. Objektif: Penelitian ini bertujuan untuk mengetahui korelasi antara kadar vitamin D dengan indeks aterogenik plasma pada mahasiswa penyandang obes. Metode: Penelitian ini merupakan penelitian analitik observasional dengan desain cross sectional yang dilakukan di Fakultas Kedokteran Universitas Andalas dan Laboratorium Sentral RSUP Dr. M. Djamil Padang dari bulan Agustus 2020 hingga April 2021. Subjek penelitian ini adalah 30 mahasiswa angkatan 2017-2018 penyandang obes di Fakultas Kedokteran Universitas Andalas, yang terdiri dari 16 orang laki-laki dan 14 orang perempuan. Hasil: Hasil penelitian didapatkan rerata umur subjek 19,57±0,86 tahun dan rerata IMT 32,53±4,13 kg/m2. Rerata kadar vitamin D subjek 13,90±4,10 ng/mL dan rerata indeks aterogenik plasma subjek -0,025±0,237. Analisis bivariat didapatkan korelasi negatif sangat lemah dan tidak bermakna antara kadar vitamin D dengan indeks aterogenik plasma (r= -0,129; p= 0,498). Kesimpulan: Tidak terdapat korelasi yang bermakna antara kadar vitamin D dengan indeks aterogenik plasma pada mahasiswa penyandang obes.
Comparison in Levels of Interleukin 6, Ferritine and Neutrophil-Lymphocyte Ratio in COVID-19 Patiens Treated in ICU and Non-ICU Nanda Oktavia; Efrida Efrida; Zelly Dia Rofinda
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 16 No 2 (2022): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v16i2.4891

Abstract

Inflammation is caused by infectious diseases, including COVID-19. Severe inflammatory responses contribute to weak adaptive immune response, there by resulting in immune response imbalance. Circulating biomarkers can represent inflammation and immune status are potential predictors for the prognosis of COVID-19 patients. Ferritin and interleukin-6 can serve as significant biomarkers in the detection of cytokine storm, systemic inflammation, and the prognosis of COVID-19. Neutrophil-lymphocyte ratio is an independent prognostic biomarker for COVID-19 patients. The aim of this study to determine differences levels of IL-6, ferritin, and NLR in COVID-19 patients treated ICU and non-ICU. This study was comparative cross-sectional design of 62 COVID-19 patients. Research was conducted at the Central Laboratory and Medical Record of Dr. M. Djamil Padang hospital (May-September 2021). Interleukin-6 levels determined the ECLIA methods, ferritin with the ELFA methods, and NLR with calculation methods. Bivariate data were analyzed with Mann-Whitney test. The characteristics of COVID-19 patients treated in ICU: 64.5% male, average age was 53.52(10.71) years, 48.4% death, and non ICU: female 71.0%, average 42.32 (12.22) years, and recovered 100%. The most common comorbid is hypertension. There were significant differences levels of IL-6, ferritin, and NLR in ICU and non-ICU patients with COVID-19 (p<0.001).
Correlation between Mean Platelet Volume and Procalcitonin in Sepsis Patients Rama Dhanivita Djamin; Zelly Dia Rofinda; Desywar Desywar
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 29, No 1 (2022)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v29i1.1917

Abstract

Sepsis is a clinical condition of potentially life-threatening organ dysfunction caused by the host's response to infection. Delayed diagnosis and treatment of sepsis lead to worsening of the disease, which can lead to circulatory collapse, multiple organ failure, and death, therefore accurate and timely diagnosis can prevent death. Procalcitonin (PCT) is the most widely used, studied, and promising marker for the diagnosis of sepsis. Recent studies have shown that procalcitonin plays an important role in the clinical diagnosis of sepsis because it can differentiate sepsis from SIRS. Most studies found an increase in the Mean Platelet Volume (MPV) in septic patients, both neonates, and adults. The MPV value can be used as a parameter to assess the prognosis of septic patients. This cross-sectional analytical study was conducted on 21 septic patients at Dr. M. Djamil Hospital, Padang from January 2020 to April 2021. Mean platelet volume values were determined using an automatic hematology analyzer based on the formula made by the device. Procalcitonin levels were measured using the enzym-linked immunofluorescent assay method. Data were analyzed by Pearson correlation test and p < 0.05 was significant. The mean age of the research subjects was 54 years and the range was 22-77 years. The number of male and female research subjects in this study was almost the same, consisting of 10 male (48%) and 11 female (52%) patients. The average MPV was 10.59(0.56) fL and the median procalcitonin was 9.35(2.08-200) ng/mL. Pearson correlation test showed that MPV was positively correlated with procalcitonin with moderate correlation (r=0.435, p=0.049). There was a moderate positive correlation between MPV and procalcitonin in septic patients.
Profil Kasus pada Ibu Hamil yang Dirawat dengan Covid-19 di RSUP Dr. M. Djamil Padang Periode Januari—Desember 2020 Salsabila Dhiyaa Syifa; Mohamad Reza; Zelly Dia Rofinda; Puja Agung Antonius; Firdawati Firdawati; Biomechy Oktomalio Putri
Jurnal Ilmu Kesehatan Indonesia Vol 3 No 3 (2022): September 2022
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v3i3.888

Abstract

Latar Belakang: Coronavirus Disease 2019 (COVID-19) adalah penyakit pada saluran pernafasan yang diakibatkan oleh Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Virus ini dapat menginfeksi kelompok rentan, termasuk ibu hamil. Penelitian ini bertujuan untuk mengetahui gambaran profil kasus pada ibu hamil yang dirawat dengan COVID-19. Objektif: Penelitian ini bertujuan untuk mengetahui gambaran profil kasus pada ibu hamil yang dirawat dengan COVID-19 di RSUP Dr. M. Djamil Padang Periode Januari—Desember 2020. Metode: Penelitian ini menggunakan metode deskriptif dengan desain cross-sectional di RSUP Dr. M. Djamil Padang dengan jumlah sampel sebanyak 136 ibu hamil dengan COVID-19 pada tahun 2020. Data yang digunakan berupa data sekunder dari rekam medis dengan menggunakan teknik total sampling. Hasil: Ibu hamil yang terpapar COVID-19 memiliki gejala ringan (95,6%), berada pada usia tidak berisiko (83,8%),berada pada kehamilan trimester III (87,5%), dan terpapar tanpa komorbid (81,6%). Didapatkan juga peningkatan kadar NLR dan D-Dimer, banyak yang mendapat tindakan berupa sectio caesarea (64,7%), dan adanya kematian 3 ibu (2,2%). Kesimpulan: Sebagian besar ibu hamil dengan COVID-19 memiliki gejala ringan, berada pada usia tidak berisiko (usia 20—35 tahun), hamil pada trimester III, terpapar tanpa komorbid, memiliki peningkatan NLR dan D-Dimer, dilakukan tindakan sectio caesarea, dan tidak banyak terjadi kasus kematian.
Correlation between Mean Platelet Volume and Procalcitonin in Sepsis Patients Rama Dhanivita Djamin; Zelly Dia Rofinda; Desywar Desywar
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 29 No. 1 (2022)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v29i1.1917

Abstract

Sepsis is a clinical condition of potentially life-threatening organ dysfunction caused by the host's response to infection. Delayed diagnosis and treatment of sepsis lead to worsening of the disease, which can lead to circulatory collapse, multiple organ failure, and death, therefore accurate and timely diagnosis can prevent death. Procalcitonin (PCT) is the most widely used, studied, and promising marker for the diagnosis of sepsis. Recent studies have shown that procalcitonin plays an important role in the clinical diagnosis of sepsis because it can differentiate sepsis from SIRS. Most studies found an increase in the Mean Platelet Volume (MPV) in septic patients, both neonates, and adults. The MPV value can be used as a parameter to assess the prognosis of septic patients. This cross-sectional analytical study was conducted on 21 septic patients at Dr. M. Djamil Hospital, Padang from January 2020 to April 2021. Mean platelet volume values were determined using an automatic hematology analyzer based on the formula made by the device. Procalcitonin levels were measured using the enzym-linked immunofluorescent assay method. Data were analyzed by Pearson correlation test and p < 0.05 was significant. The mean age of the research subjects was 54 years and the range was 22-77 years. The number of male and female research subjects in this study was almost the same, consisting of 10 male (48%) and 11 female (52%) patients. The average MPV was 10.59(0.56) fL and the median procalcitonin was 9.35(2.08-200) ng/mL. Pearson correlation test showed that MPV was positively correlated with procalcitonin with moderate correlation (r=0.435, p=0.049). There was a moderate positive correlation between MPV and procalcitonin in septic patients.
Correlation between PLR and NLR with Tumor Size in Breast Cancer Patients Sri Widyaningsih; Zelly Dia Rofinda
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 30 No. 3 (2024)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v30i3.2199

Abstract

Breast cancer is the most common malignancy in females globally and one of the main causes of cancer death. There are several markers of cancer-related inflammation to help predict the relationship between pathologic characteristics of breast cancer. The research objective was to analyze the correlation between PLR and NLR with associated tumor size in breast cancer. This was a retrospective study with a cross-sectional design. This study used secondary data from the medical records of breast cancer patients who met the inclusion criteria at Siti Khodijah Hospital, Sidoarjo from January 2021 to March 2023. The sample size was 54 subjects, patients with breast cancer confirmed by pathology anatomy. The exclusion criteria were patients with infection, autoimmune disease, and hematology disorder. All the subjects were female. The mean age at the time of breast cancer diagnosis was 50.18±10.23 years, range of 27-80 years old. Most of the patients were over 50 years as much as 28 (51.85 %), while there were 26 (48.14%) > 50 years. The PLR range was  15.45-600.0, the NLR range was  0.58-9.98, tumor size range was 0.5-10.0 cm. Correlation between PLR and NLR with tumor size in breast cancer (p=0.351 and p=0.339). Correlation analysis showed that PLR and NLR had no significant correlation with tumor size ( r= -0.129, p=0.351 and r= -0.133, p=0.339). In conclusion, there is no significant correlation between PLR and NLR with histopathology of tumor size in patients with breast cancer.
Hubungan hidronefrosis pra operasi dengan penurunan hemoglobin pasca operasi percutaneous nephrolithotomy di RSUP Dr. M. Djamil Padang Febby Genta Wahyuni; Alvarino Alvarino; Zelly Dia Rofinda; Etriyel MYH; Taufik Ashal; Mohamad Reza
Majalah Kedokteran Andalas Vol 46, No 11 (2024): July 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v46.i11.p1825-1838.2024

Abstract

Tujuan : Penelitian ini bertujuan untuk melihat hubungan hidronefrosis pra operasi dengan penurunan hemoglobin pasca PCNL pada penderita batu ginjal; Metode: Penelitian ini merupakan penelitian analitik dengan pendekatan prospektif. Jumlah dari sampel dalam penelitian ini sebanyak 21 sampel di RSUP Dr. M. Djamil Padang. Analisis data menggunakan uji Chi square dimana hubungan antar variabel dikatakan signifikan jika p value < 0,05;  Hasil:  Penelitian menunjukkan bahwa  21 pasien yang dioperasi PCNL, jumlah jenis kelamin terbanyak yakni pada perempuan dan berada pada rentang usia 46-64 tahun. Penurunan hemoglobin terbanyak  berada pada kelompok <2g/dl. Kebanyakan pasien batu ginjal disertai dengan adanya hidronefrosis. Analisis statistik menunjukkan bahwa tidak ada hubungan antara hidronefrosis pra operasi dan penurunan hemoglobin setelah PCNL (p value = 0,553); Simpulan: Tidak terdapat hubungan yang bermakna antara hidronefrosis pra operasi dengan penurunan hemoglobin pasca PCNL pada penderita batu ginjal di RSUP Dr.M.Djamil Padang.
The Relationship between Albumin Levels with SGOT, SGPT, and de Ritis Ratio in Chronic Hepatitis B Patients: A Single-Center Observational Study at Dr. M. Djamil General Hospital, Padang, Indonesia Ami Tri Nursasmi; Zelly Dia Rofinda; Desywar
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 9 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i9.1074

Abstract

Background: Chronic hepatitis B (CHB) is a persistent hepatitis B virus (HBV) infection and can cause progressive liver damage. This damage can be measured through a decrease in albumin levels and an increase in liver enzymes such as aspartate aminotransferase (AST/SGOT), alanine aminotransferase (ALT/SGPT), and de Ritis ratio (AST/ALT). This study aims to analyze the relationship between albumin levels and SGOT, SGPT, and de Ritis ratio in CHB patients. Methods: This cross-sectional retrospective analytical study involved 50 CHB patients diagnosed at Dr. M. Djamil General Hospital Padang between June 2022 to June 2023. Data on albumin levels, SGOT, SGPT, and de Ritis ratio were obtained from medical records. The de Ritis ratio, SGOT, and SGPT were grouped into normal and increased. Statistical analysis used an independent t-test with a significance of p < 0.05. Results: The research subjects consisted of 26 men (52%) and 24 women (48%) with an average age of 42.46 ± 13.39 years. The mean albumin level in the increased SGOT group (3.69 ± 0.78 g/dL) was significantly lower than the normal SGOT group (4.39 ± 0.61 g/dL) (p = 0.003). The mean albumin level in the increased de Ritis ratio group (3.90 ± 0.80 g/dL) was also significantly lower than the normal de Ritis ratio group (4.46 ± 0.70 g/dL) (p = 0.006). There was no significant difference between albumin levels in the normal and increased SGPT groups (p = 0.548). Conclusion: There is a significant negative relationship between albumin levels and SGOT and de Ritis ratio in CHB patients. Decreased albumin levels may be an indicator of more severe liver damage in these patients.
Co-Authors Adelin, Prima Afriwardi Afriwardi Aisah Aisah Aisyah Elliyanti Aisyah Ellyanti Aldian Mulyanto Lokaria Aldian Mulyanto Lokaria Alles Firmansyah Almurdi Almurdi Alqadri Alqadri Alvarino Amanda Rizki Ami Tri Nursasmi Andry Kurniawan Andry Kurniawan Antonius, Puja Agung Arina Widya Murni Ashal, Taufik Asterina Asterina Aswiyanti Asri Berliana Islamiyarti Hydra Berliana Islamiyarti Hydra Bobby Indra Utama Daan Khambri Daulat Azhari Dessy Arisanti Desta Purwati Desywar Desywar Desywar Desywar Desywar Dian Jenova Dian Pertiwi Dian Pertiwi Dinda Aprillia Dinda Aprillia Dwi Yulia Edison Edison Efrida Efrida Efrida Elizabeth Bahar Ellyza Nasrul Elmatris Sy Elvinawaty Elvinawaty Endrinaldi Endrinaldi Endrinaldi Erkadius Erkadius Eti Yerizel Etriyel Myh Fadil Oenzil Fauzan Arisyi Koto Fauzar Fauzar Fauzar Fauzar Febby Genta Wahyuni Febrita Joniarti Feby Febriatama Fiona Septi Mulya Firdawati Firdawati Gusti Revilla Hanifah Maani Hanifah Maani Hasmiwati Hendriati, Hendriati Hevrina Yufani Hevrina Yufani Husna Yetti Husni Husni Husni Husni Husni Husni Husnil Kadri Husnil Wardiyah Ira Ferawati Julizar Julizar Julizar Julizar M. Ikhlasul Amal Eel Taslim Masrul Masrul Syafri Mohamad Reza Najirman Najirman Nanda Oktavia Nur Izzah Atirah Hardinur Putri Auliya Putri, Biomechy Oktomalio Rahmat Syawqi Rahmat Syawqi Rama Dhanivita Djamin Rani Novelty Rauza Sukma Rita Ricca Fitria Rika Susanti Rikarni Rikarni Rina Gustia Risma Isti Rismawati Yaswir Rizanda Machmud Rizki Rahmadian Rosfita Rasyid Rulli Firmansyah Salsabila Dhiyaa Syifa Saptino Miro Sharon Serafim Bosawer Siti Nurhajjah Sri Widyaningsih Suswita, Rini Tuti Asryani Verbrini Rifnayeni Willy Valerian Wirsma Arif Yashinta Octavian Gita Setyanda Yulistini, Yulistini Yusrawati Yusrawati Yustini Alioes