Article Per Year (5 Year)
p-Index From 2021 - 2026
3.492
P-Index
This Author published in this journals
All Journal HAYATI Journal of Biosciences VALENSI JURNAL KIMIA SAINS DAN APLIKASI Jurnal Ilmu dan Teknologi Hasil Ternak The Journal of Experimental Life Sciences (JELS) Journal of Degraded and Mining Lands Management Indonesian Green Technology Journal Jurnal Pembangunan dan Alam Lestari Natural B The Journal of Pure and Applied Chemistry Research Journal of Mathematical and Fundamental Sciences JURNAL PENGABDIAN KEPADA MASYARAKAT Science and Technology Indonesia Jurnal Penelitian Pendidikan IPA (JPPIPA) Indonesian Journal of Chemistry JMM (Jurnal Masyarakat Mandiri) PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Pengabdian kepada Masyarakat Nusantara
Arie Srihardyastutie
Chemistry Department Brawijaya University
Agriculture, Biological Sciences & Forestry Arts Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Physics Public Health Social Sciences Other

Published : 38 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 38 Documents
Search

 1   2   3   4 
Hibridisasi Sintesis dan Uji Aktivitas Antikanker Turunan Baru Asam Karboksilat secara In-Silico dan In-Vitro Asyfariatus Zulfa Azhar; Warsito Warsito; Arie Srihardyastutie
Jurnal Penelitian Pendidikan IPA Vol. 9 No. 9 (2023): September
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i9.3439

Abstract

Design of new compounds as active ingredients of drugs must be selective and efficient to achieve therapeutic efficacy and minimize resulting side effects. Hybridization synthesis approaches using major components of essential oils can reliably generate new molecules that are superior as active ingredients of anti-cancer drugs due to their cytotoxic properties. This study synthesized a hybrid molecule of citronellyl salicylate by an esterification reaction using Steglich and Fisher method under ultrasonic assistance. The Steglich esterification is more efficient in producing citronellyl salicylate during 30 minutes reaction, yield 12.45%. Analysis of the synthesized product by FTIR is characterized by the presence of typical absorptions of the ester group at ῡ 1650 cm-1 and 1270 cm-1, while LC ESI-MS shows m/z 294 is indicated [M+NH4]+. Anticancer activity was tested in-silico for protein receptors MMP-9, MMP-2, Cyclin-A, p53, and BAK using Molecular Docking Pyrx 9.0 and the highest activity was shown binding affinity value -8.4 kcal/mol for the MMP-9 protein receptor. Similarly, the results of the in vitro activity assay of citronellyl salicylate to 4T1 breast cancer cells showed that the morphology of cancer cells was damaged and the viability of cancer cells was lower than that of normal cells
PENDAMPINGAN ECO-LITERASI DALAM MENDUKUNG GERAKAN SEDEKAH SAMPAH INDONESIA (GRADASI) MENUJU SEKOLAH ADIWIYATA SE-KOTA MALANG Isaskar, Riyanti; Pratiwi, Destyana Ellingga; Pertiwi, Vi’in Ayu; Srihardyastutie, Arie; Fajar, Yusri
JURNAL PENGABDIAN KEPADA MASYARAKAT Vol 30, No 1 (2024): JANUARI-MARET
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jpkm.v30i1.50400

Abstract

Permasalahan lingkungan tengah menjadi sorotan hingga kancah internasional. Adiwiyata merupakan salah satu bentuk perilaku hijau di lingkungan sekolah mengingat program adiwiyata memiliki tujuan untuk menciptakan kondisi sekolah yang baik dan nyaman melalui lingkungan sekitar sekolah. Sikap eco-literasi di tingkat sekolah dapat dipupuk dengan cara menerapkan prinsip 3R (Reduce, Reuse, dan Recycle). Prinsip Reduce (mengurangi) terdapat pada program gradasi, sedangkan Reuse dan Recycle terdapat pada program pembuatan Eco Enzyme dan produk turunannya. Gradasi merupakan program yang diadakan untuk mengurangi jumlah sampah plastik yang kian hari semakin meningkat. Kegiatan pengabdian masyarakat yang diberi nama BRILIAN dilaksanakan pada rentang waktu 27 Juni - 19 Agustus 2022. kegiatan yang melibatkan siswa, metode yang digunakan adalah presentasi dan praktik. Materi yang disampaikan diantaranya adiwiyata, GRADASI, eco-enzyme, dan kompos. Tahapan kegiatan program BRILIAN terbagi menjadi tiga tahapan yakni pra-kegiatan, kegiatan inti dan pasca-kegiatan. Pra-kegiatan berisi webinar untuk mengetahui sekolah yang belum atau sudah berpredikat adiwiyata, kegiatan inti berisi kegiatan sosialisasi dan praktik di sekolah yang melibatkan guru dan siswa dan pasca-kegiatan berisi kegiatan monitoring dan evaluasi dari kegiatan yang sudah dilakukan. 
Study of Eugenol and Salicylic Acid Interactions in Hybrid Molecule Encapsulated for Enhanced Antioxidant Endah Setiani Astuti; Warsito, Warsito; Srihardyastutie, Arie
Indonesian Green Technology Journal Vol. 12 No. 2 (2023): Indonesian Green Technology Journal
Publisher : Graduate School, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.igtj.2023.012.02.02

Abstract

Drug development continues to be carried out so that drugs can work effectively. Creating a drug formula can be achieved by combining two or more synergistic drug compounds by hybridization, blending, or synthesis. This study reports findings of antioxidant activity using the good DPPH method from the synthesis of eugenol and salicylic acid using the encapsulation technique. The encapsulation technique uses chitosan as a coating material to protect the active ingredients, taking advantage of its unique functional characteristics, including the ability to form bonds with the crosslink agent sodium tripolyphosphate (Na-TPP) at a speed of 13,500 rpm with a pH of 4.2 to optimize the formulation. The encapsulation system produced majority particles measuring 241.0 ± 19.8 nm, with an encapsulation efficiency of 58.29 ± 0.40%. The results of the compound antioxidant test (CS-ES NP) showed better results than pure ES, with an IC50 value of 1.64 ?g/mL. The morphology results after encapsulation showed round and dense particles, indicating that the ES compound was successfully encapsulated. Keywords: encapsulation, antioxidant, eugenyl salicylate, blending
Crystallization of [Zn(Pyrazinamide)₂(Cl)₂] Complex and In Vitro Antibacterial Activity of the Complex Against E. coli and S. aureus Naila Azmi Adiba; Danar Purwonugroho; Arie Srihardyastutie; Yuniar Ponco Prananto
Jurnal Kimia Sains dan Aplikasi Vol 27, No 9 (2024): Volume 27 Issue 9 Year 2024
Publisher : Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jksa.27.9.436-443

Abstract

A complex of [Zn(pza)2(Cl)2], pza = pyrazinamide, was successfully crystallized from methanol or ethanol solvents with different morphology. The complex was synthesized using the solution method in ZnCl2: pza mol ratios of 1:2 and 1:4 in both ethanol and methanol solvents. FTIR and single crystal XRD analyses were done to confirm the complex. The complex was then used for in vitro antibacterial test against E. coli and S. aureus. Experimental data shows that the type of solvent and metal-to-ligand mol ratio yields the same compound, resulting in colorless crystals that melt at 234-236°C. Large block crystals were obtained from the methanolic solution, while a higher yield was obtained from the use of a higher mol ratio of 1:4. Infrared spectra analysis confirms the presence of characteristic carbonyl and amide groups of the pza ligand. Meanwhile, single crystal XRD screening indicates that unit cell parameters of the crystals from both solvents are identical to a known zinc(II)-pza complex. In vitro antibacterial tests against E. coli and S. aureus show that the complex had much better activity than the ZnCl2 and the free pza. In addition, the complex performs better antibacterial activity toward gram-positive S. aureus than the gram-negative E. coli.
Nanoparticle-Enhanced 3D-Connector Microfluidic Paper-Based Analytical Device (3D-µPADs) for Sensitive and Cost-Effective Detection of Albumin-Creatinine Ratio in Urine Sample Sabarudin, Akhmad; Fiddaroini, Saidun; Fahmi, Ahmad Luthfi; Roja’i, Abdul Munir; Salsabila, Isadora Evani; Aulanni’am; Srihardyastutie, Arie; Susanti, Hani; Samsu, Nur
Science and Technology Indonesia Vol. 10 No. 2 (2025): April
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2025.10.2.504-518

Abstract

Chronic kidney disease (CKD) is a global health challenge affecting over 800 million people worldwide. Early detection is crucial to prevent progression to end-stage renal disease (ESRD), where life-saving interventions like dialysis or transplantation are necessary. Among the markers for early kidney damage, the Albumin Creatinine Ratio (ACR) in urine is one of the most reliable. Conventional methods of ACR detection, such as LC/MS-MS and ELISA, are highly accurate but require expensive equipment and skilled personnel, limiting their accessibility, especially in resource-limited settings. To address this, we developed a 3D-connector microfluidic paperbased analytical device (3D-µPADs) enhanced with gold nanoparticles (AuNPs) for sensitive and low-cost ACR detection. The integration of AuNPs amplifies colorimetric signals, enhancing the visual distinction in albumin detection. Our 3D-µPADs werefabricated using chromatographic paper Whatman No. 1 with hydrophobic barriers created by solid wax printing, followed by reagent immobilization for albumin and creatinine detection. The colorimetric and distance responses, based on reactions with Bromocresol Green (BCG) and Chrome Azurol S-Palladium (CAS-Pd2+), were analyzed using ImageJ software to quantify albumin and creatinine levels. The 3D-µPADs exhibited optimal sensitivity and accuracy, with linear detection ranges for albumin and creatinine of 30–400 mg/g. Validation with human urine samples demonstrated an accuracy of 93.04%, suggesting that 3D-µPADs offer a promising alternative for early nephropathy detection. Our findings provide a cost-effective, accessible tool for CKD screening, potentially transforming diagnostics in low-resource environments.
Development of Fermented Coconut Water and Red Ginger using Next Generation Probiotics as a Potential Biological Activity Agent Nabila, Sofi; Srihardyastutie, Arie; Aulanni’am, Aulanni’am; Ardiyati, Tri
HAYATI Journal of Biosciences Vol. 32 No. 5 (2025): September 2025
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.4308/hjb.32.5.1337-1351

Abstract

Degenerative diseases have increased in prevalence worldwide, predominantly in Indonesia. Some studies found that probiotics have an impact on organic substances that address inflammation and gut microbiota imbalance. This study aims to develop a functional beverage based on coconut water and red ginger fermentation using Next Generation Probiotics (NGP) and characterize the product using metagenomic and metabolomic technologies. This experimental study involved the fermentation of coconut water and red ginger using a probiotic starter identified by 16S rRNA sequencing for 120 hours at room temperature. The analysis included microbial characterization using List the probiotics metagenomic sequencing, metabolite profiling by LC-HRMS, particle size by PSA, and in vitro antibacterial and anti-inflammatory activity testing. Metagenomic analysis identified the dominance of the family Acetobacteraceae (45%) and genus Acetobacter 942%. Fermentation reduced the tannin content by 28.5% and increased the number of metabolite compounds from 37 to 54. The fermentation results also showed antibacterial activity against E. coli CNN 0091 (inhibition zone 7.835 mm), and anti-inflammatory activity reached 1,000%. The combination of coconut water, red ginger, and NGP produced a complex metabolite profile with high therapeutic potential. The findings show significant potential for the prevention of degenerative diseases.
PENDAMPINGAN ECO-LITERASI DALAM MENDUKUNG GERAKAN SEDEKAH SAMPAH INDONESIA (GRADASI) MENUJU SEKOLAH ADIWIYATA SE-KOTA MALANG Isaskar, Riyanti; Pratiwi, Destyana Ellingga; Pertiwi, Vi’in Ayu; Srihardyastutie, Arie; Fajar, Yusri
JURNAL PENGABDIAN KEPADA MASYARAKAT Vol. 30 No. 1 (2024): JANUARI-MARET
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jpkm.v30i1.50400

Abstract

Permasalahan lingkungan tengah menjadi sorotan hingga kancah internasional. Adiwiyata merupakan salah satu bentuk perilaku hijau di lingkungan sekolah mengingat program adiwiyata memiliki tujuan untuk menciptakan kondisi sekolah yang baik dan nyaman melalui lingkungan sekitar sekolah. Sikap eco-literasi di tingkat sekolah dapat dipupuk dengan cara menerapkan prinsip 3R (Reduce, Reuse, dan Recycle). Prinsip Reduce (mengurangi) terdapat pada program gradasi, sedangkan Reuse dan Recycle terdapat pada program pembuatan Eco Enzyme dan produk turunannya. Gradasi merupakan program yang diadakan untuk mengurangi jumlah sampah plastik yang kian hari semakin meningkat. Kegiatan pengabdian masyarakat yang diberi nama BRILIAN dilaksanakan pada rentang waktu 27 Juni - 19 Agustus 2022. kegiatan yang melibatkan siswa, metode yang digunakan adalah presentasi dan praktik. Materi yang disampaikan diantaranya adiwiyata, GRADASI, eco-enzyme, dan kompos. Tahapan kegiatan program BRILIAN terbagi menjadi tiga tahapan yakni pra-kegiatan, kegiatan inti dan pasca-kegiatan. Pra-kegiatan berisi webinar untuk mengetahui sekolah yang belum atau sudah berpredikat adiwiyata, kegiatan inti berisi kegiatan sosialisasi dan praktik di sekolah yang melibatkan guru dan siswa dan pasca-kegiatan berisi kegiatan monitoring dan evaluasi dari kegiatan yang sudah dilakukan. 
Battery Performance Analysis of Solar Cell Powered Water Purification System: Case Study of Indonesian Army Polytechnic in Batu - East Java Hidayat, Muhammad Iman; Mardiana, Diah; Srihardyastutie, Arie; Komara, Acep Nana
Jurnal Pembangunan dan Alam Lestari Vol. 16 No. 2 (2025): Jurnal Pembangunan dan Alam Lestari
Publisher : Postgraduate School of Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jpal.2025.016.02.07

Abstract

A solar cell-powered water purification system (SC-WPS) was developed and installed to generate clean water using renewable energy at the Polytechnic of the Indonesian Army (POLTEKAD). Developed and implemented using renewable energy from a 100 Wp solar panel, a solar cell-powered water purification system (SC-WPS) was designed to address this issue. The battery performance of the system is the primary focus of this work, encompassing battery discharge, state of charge (SOC), and key electrical parameters such as voltage, current, power, and solar irradiation data. Under test, the solar panel generated up to 495.7 Wh/day with a peak power of 93.28 W. Although the voltage remained between 12.78 V and 12.84 V, the battery depletion process showed stability; the total energy generated increased from 92.2 Wh in the first hour to 766.1 Wh by the tenth hour. Although the solar panel efficiency of the system peaked at 15.2%, factors such as uneven sunshine and energy loss caused it to decline over time. These results underscore the need to maximize battery capacity and solar panel efficiency to ensure continuous system operation for water purification in areas with varying sunshine levels. Keywords: battery performance, clean water, energy efficiency, Solar cell
Training on Bioconversion of Coffee Pulp Waste into Vegan Leather Raw Material in Dusun Krajan, Tegalharjo, Glenmore, Kabupaten Banyuwangi Ardyati, Tri; Mora, Giral Baines; Permatasari, Dewi; Maulidiyah, Nuris Shobah; Wahyudi, Aleyda Nur Halizah; Srihardyastutie, Arie; Poerwadi, Bambang; Zubaidah, Elok
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 10 No. 11 (2025): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v10i11.9473

Abstract

Banyuwangi is the largest coffee plantation centre in East Java, with robusta and arabica coffee production reaching 10,518 tonnes per year. Coffee plantation waste, which is abundant, is known as coffee pulp. Coffee pulps can be converted into organic compost/fertilizer, animal feed, and eco-friendly products such as cellulose-based nata/membrane. The abundant availability of coffee pulp waste in Banyuwangi Regency has not been correctly handled or processed to prevent environmental impact. Converting coffee pulp waste into eco-friendly products will benefit the surrounding community and increase the added value of the waste. To overcome these problems, it is necessary to engage in activities involving the local community, local government, and agro-tourism actors through counseling and training on processing coffee pulp waste/bioconversion into eco-friendly products, thereby benefiting the community in Banyuwangi Regency, especially in the Glenmore area. Training participants were given a questionnaire for assessment. Based on the results of the questionnaire analysis, it is known that the participants' understanding before the activity is: 40% of participants were very poorly understood, 13% were poorly understood, 20% were quite understood, 13% understood, and 13% were very familiar with the material of processing coffee pulp waste. After receiving training, 27% of participants achieved an excellent understanding, 33% had a moderate understanding, and 33% had a somewhat understanding. Additionally, there were still participants who did not understand as much as 7%. Based on the participants' assessment, 67% felt that the benefits of this activity were excellent and should be carried out on an ongoing basis.
Bioremediation of the Lapindo mud contaminated soil using eco-enzyme: Case of a total petroleum hydrocarbon removal Sulistiyaningrum, Dwi Rakhmatun; Rumhayati, Barlah; Srihardyastutie, Arie
Journal of Degraded and Mining Lands Management Vol. 13 No. 1 (2026)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15243/jdmlm.2026.131.9659

Abstract

This research investigated the effectiveness of bioremediation of Lapindo mud-contaminated soil using an eco-enzyme for total petroleum hydrocarbons (TPH) removal. The soil samples were collected from Glagaharum and Gedang Villages, Sidoarjo, East Java, Indonesia, which have been contaminated by the Lapindo mud containing TPH. The bioremediation experiment was carried out ex situ in a container filled with contaminated soil samples, which were watered with eco-enzymes daily. Bioremediation time was optimized at 0, 7, 4, 21, and 28 days while the eco-enzymes concentration was varied at 0, 5, 10, and 15% (v/v). The concentration of TPH in the soil samples was analyzed using the gravimetric method at 0, 7, 4, 21, and 28 days. The results showed that TPH concentration was gradually decreased during remediation. The remediation removal percentage reached an optimum after 21 days. The TPH was optimally removed using the eco-enzyme at 15% (v/v), achieving 95.39%. The bioremediation of contaminated soil using eco-enzymes also increased the contents of total C and total N by 50.97% and 39.43%, respectively. However, this treatment reduces total P by 50.89%. Furthermore, the pH and temperature values for the three samples before and after the bioremediation process remained fairly stable, within the pH range of 6-7 and the temperature range of 25.7-26.2 °C.
Co-Authors Achmad Rudijanto Agustina Shinta Hartati Wahyuningtyas Akhmad Sabarudin Alyaa Farrah Dibha Andreas Budi Wijaya Angelina Rosmawati Ani Mulyasuryani Anisa Aprilia Anna Roosdiana Anna Roosdiana Anna Roosdiana Anna Roosdiana Antula, Yulianti Asyfariatus Zulfa Azhar Aulanni'am Aulanni'am Aulanni'am, Aulanni'am Aulanni'am, Aulanni'am Aulanni`am Aulanni`am Aulanni’am Aulanni’am Aulanni’am Aulanni’am Aulanni’am Aulanni’am Aulanni’am, Aulanni’am Azor Yulianus Tefa Bambang Poerwadi Barlah Rumhayati Barlah Rumhayati Barlah Rumhayati Chanif Mahdi Chanif Mahdi Chanif Mahdi Chanif Mahdi Chanif Mahdi Chanif Mahdi Danar Purwonugroho Destyana Ellingga Pratiwi Destyana Ellingga Pratiwi Devi Ramadani Dewi Permatasari, Dewi Diah Mardiana Dyah Kinasih Wuragil Elok Zubaidah Elvina Dhiaul Iftitah Endah Setiani Astuti Eny Rahma Wati Eva Nur Laili Octaviana Fahmi, Ahmad Luthfi Fahriyah Fahriyah Faijal Fachrudin Mbabho Faradis, Taritsu Hazal Fiddaroini, Saidun Fitria Rahmawati Gunawan, Firza Rajasa Habibi, Ananta Naufal Hani Susanti, Hani Janatun Na’imah Kato, Masashi KIKI FIBRIANTO Komara, Acep Nana Latifah Tribuana Dewi Luluk Indri Astuti Made Oka Adnyana Made Oka Adnyana Maria Natalia Wewo Masruri Masruri Maulidiyah, Nuris Shobah Moh. Farid Rahman Mora, Giral Baines Muhammad Asadullah Muhammad Iman Hidayat, Muhammad Iman Nabila, Sofi Naila Azmi Adiba Neno, Dolly Irnawati Nur Aeni Nur Lailah Nur Samsu Pertiwi, Vi’in Ayu Pertiwi, Vi’in Ayu Putranty Widha Nugraheni Qonitah Fardiyah Riyanti Isaskar Roja’i, Abdul Munir Rulli Rosandi Rurini Retnowati Safitri, Anna Salsabila, Isadora Evani Sasangka Prasetyawan Sasangka Prasetyawan Sasangka Prasetyawan Sasangka Prasetyawan Sasangka Prasetyawan Sasangka Prasetyawan Sasangka Prasetyawan Siti Nurul Afifah Sofi Nabila Sukardi, Ernawati Sulistiyaningrum, Dwi Rakhmatun Sutrisno Sutrisno Sutrisno, Sutrisno Tri Ardiyati Tri Ardyati Tri Ardyati Velayaty Labone Azzahra Vi’in Ayu Pertiwi Wahyudi, Aleyda Nur Halizah Warsito Warsito Warsito Warsito Wasino Wasino Yudita Prihatini Puji Rahma Sari Yuniar Ponco Prananto Yusri Fajar Yusrina, Nur