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VISKOSITAS DARAH DAN ASPEK MEDISNYA Lili Irawati
Majalah Kedokteran Andalas Vol 34, No 2 (2010): Published in August 2010
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (597.53 KB) | DOI: 10.22338/mka.v34.i2.p102-111.2010

Abstract

AbstrakFaktor-faktor yang mempengaruhi viskositas darah adalah: a) Hematokrit : hematokrit yang meningkat akan diikuti viskositas darah yang meningkat. b) Suhu tubuh: bila suhu tubuh naik, viskositas turun. c) Kadar protein plasma: bila kadarnya naik maka viskositas naik dan sebaliknya. d) Kecepatan aliran darah: bila kecepatan aliran darah turun maka viskositas naik. e) Diameter pembuluh darah: bila diameter pembuluh darah kurang dari 1,5 mm, maka efek viskus jauh lebih sedikit.Aplikasi pada Hukum Poiseuille, menyatakan bahwa kecepatan aliran darah bergantung pada radius, ketika radius meningkat dua kali lipat maka kecepatan aliran darah meningkat menjadi 16 kali. Demikian juga ketika radius dibuat lebih kecil, kecepatan aliran menurun secara drastis seperti penebalan pada dinding arteri, akan menurunkan kecepatan aliran darah seperti pada angina pectoris, penyebab tersering adalah arteriosclerosis.Kata kunci : Viskositas darah, Hukum PoiseuilleAbstractThe factors affecting the blood viscosity are following: a) Haematocrit: increased haematocrit will be followed increased the blood viscosity. b) The body temperature: inclined the body temperature, viscosity decline. c) Plasma protein levels: when it levels increase then viscosity also increase and conversely. d) The rate of the blood flow: when the rate down, the viscosity up. e) The vessel diameter (sizes): when the diameter less than 1,5 mm, the viscous effect much less.The application to Poiseulle’s Law, suggest that the rate of blood depend on radius, once the radius increased twice then the rate of blood flow increased 16 times. Simiarly, once the radius is reduced, the rate of blood flow decrease dramaticaly such as the thickness on the artery vessel wall, will decrease the rate of blood flow such as angina pectoris, the most caused are arterioclerosis.Key word : blood viscosity, Poiseulle’s Law
UJI EFEK INFUSA BUAH MAHKOTA DEWA (Phaleria Macrocarpa Scheff Boerl) TERHADAP PENCEGAHAN PENINGKATAN KOLESTEROL DARAH PADA TIKUS PUTIH JANTAN (Rattus Novergicus) YANG DIBERI DIET LEMAK TINGGI Julizar Julizar; Lili Irawati; Erlina Rustam
Majalah Kedokteran Andalas Vol 36, No 1 (2012): Published in April 2012
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (663.333 KB) | DOI: 10.22338/mka.v36.i1.p51-61.2012

Abstract

AbstrakPenyakit jantung koroner (PJK) merupakan penyebab utama kematian di berbagai belahan dunia termasuk di Indonesia. Salah satu pemicu terjadinya PJK adalah tingginya kadar kolesterol dalam darah. Buah mahkota dewa telah lama digunakan oleh masarakat untuk menurunkan kadar kolesterol dan mengobati berbagai penyakit kardiovaskuler.Telah dilakukan penelitian untuk melihat efek infus buah mahkota dewa terhadap pencegahan peningkatan kadar kolesterol pada tikus putih jantan yang diberi diet lemak tinggi (DLT). Penelitian ini menggunakan 30 ekor Rattus novergicus jantan yang berumur 2,5 – 3 bulan dengan berat badan 250 - 350 gram. Hewan coba dibagi secara acak atas lima kelompok dan diperlakukan sebagai berikut:Kelompok I diberi diet standar 555 global feed dan 1 ml aquades, kelompok II diberi diet lamak tinggi(DLT) yang terdiri dari 2% Kolesterol, 10% kuning telur itik, 18% lemak sapi dan 78% diet standar dan 1 ml aquades, kelompok III diberi DLT dan 1 ml infus yang mengandung 97 mg mahkota dewa., kelompok IV diberi DLT dan 1 ml infus yang mengandung 194 mg mahkota dewa, kelompok V diberi DLT dan 1 ml infus yang mengandung 388 mg mahkota dewa. Infus diberikan per oral setiap hari selama 56 hari. Diet dan air minum diberikan ad libitum.Pada hari ke 0, 14, 28, 42 dan 56 darah diambil melalui vena centralis ekor untuk ditentukan kadar kolesterol totalnya secara enzimatik menggunakan KIT kolesterol CHOD-PAP merk Diasys. Absorbans diukur dengan spektrofotometer Genesis 20 pada panjang gelombang 546 nm. Data dianalisis dengan GLM pengukuran berulang dan one-way anova.Hasil penelitian menunjukan : pemberian infus yang mengandung 97, 194 dan 388 mg mahkota dewa dapat mencegah peningkatan kadar kolesterol dibanding kontrol (-). Terdapat perbedaan yang signifikan (p<0,05) antara kelompok 194 dan 388 mg dengan kelompk 97 mg, dimana kelompok 194 dan 388 mg mencegah peningkatan lebih besar. Tidak terdapat perbedaan (p>0,05) antara kelompok yang mendapat 194 dengan kelompok yang mendapat 388 mg mahkota dewa.ARTIKEL PENELITIAN52Disarankan untuk meneliti efek pencegahan peningkatan pada profil lipid yang lain dan melihat efek penurunan infus mahkota dewa pada hewan coba yang hiperkolesterolemik.Kata kunci : Mahkota dewa, kolesterolAbstractCoronary heart disease (CHD) is the leading cause of death in many parts of the world including in Indonesia. One of the triggers of CHD are high blood cholesterol levels. The Crown of God (Phaleria macrocarpa) has long been used by people to lower cholesterol and treat various cardiovascular diseases. Has done research to observe the effect of infusion Phaleria to prevent an increase in cholesterol levels in male white rats fed a high fat diet (HFD). This study used 30 male Rattus novergicus old from 2.5 to 3 months with body weight 250-350 grams. Experimental animals were randomized over five groups and treated as follows:Group I was given a standard diet 555 of global feed and 1 ml aquades, group II were given a diet high fat (HFD) consisting of 2% cholesterol, 10% of duck egg yolk, beef 18% fat and 78% standard diet and 1 ml aquades, group III was given the DLT and 1 ml infusion containing 97 mg of crown gods., group IV were given DLT and 1 ml infusion containing 194 mg crown of god, group V were given HFD and 1 ml infusion containing 388 mg the crown of god. Infusion given orally every day for 56 days. Diet and drinking water provided ad libitum.On days 0, 14, 28, 42 and 56 blood was collected via the tail vein centralis for total cholesterol is determined enzymatically using cholesterol Chod-PAP KIT Diasys. Absorbance was measured with a spectrophotometer Genesis 20 at 546 nm wavelength. Data were analyzed by GLM repeated measurements and one-way ANOVA.The results showed: the infusion containing 97, 194 and 388 mg crown of god can prevent an increase in cholesterol levels compared to controls (-).There are significant differences (p <0.05) between groups 194 and 388 mg with 97 mg faction, which groups 194 and 388 mg prevent the increase is greater. No difference (p> 0.05) between the group receiving 194 with the group receiving 388 mg crown of gods.It is advisable to examine the effect of preventing an increase in other lipid profiles and observe the effect of decreasing infusion crown of gods on hypercholesterolemic animal.Key word : Phaleria macrocarpa, cholseterol
Ekspresi Tumor Necrosis Factor-Alfa (TNF-α) dan Interleukin-10 (IL- 10) pada Infeksi Malaria Falciparum Lili Irawati; Nusirwan Acang; Nuzulia Irawati
Majalah Kedokteran Andalas Vol 32, No 1: April 2008
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (410.991 KB) | DOI: 10.22338/mka.v32.i1.p16-28.2008

Abstract

AbstrakMalaria masih menjadi masalah kesehatan di dunia terutama negara tropis karena angka kesakitan dan kematiannya yang tinggi. Infeksi Plasmodium falciparum ini dapat menimbulkan gejala yang berat sampai kematian. Perbedaan perjalanan penyakit pada masing-masing individu salah satunya dipengaruhi oleh sistim imun. Di antara zat yang ikut berpengaruh pada imunitas malaria adalah TNF-α dan IL-10, yang dihasilkan oleh sistim pertahanan tubuh terhadap parasit ini. Tujuan penelitian ini adalah untuk mengetahui ekspresi TNF-α dan IL-10 pada infeksi malaria falciparum, menggunakan rancangan explanatory secara cross sectional, dan melibatkan 25 penderita malaria falciparum dengan umur berkisar 14 – 60 tahun. Kadar TNF-α dan IL-10 dianalisis dengan metoda enzyme-linked immunosorbent assay (ELISA), dan hasil analisis dinyatakan bermakna bila didapatkan p < 0,05. Penelitian menunjukkan adanya peningkatan kadar TNF-α dengan rerata 283,10 ± 267,72 pg/ml dan peningkatan kadar IL-10 dengan rerata 196,99 ± 131,94 pg/ml pada penderita malaria falciparum, yang dalam keadaan normal tidak terdeteksi. TNF-α berkorelasi positif dengan IL-10 (r = 0,491; p > 0,05), tapi berkorelasi negatif dengan kadar hemoglobin (r =-0,189; p > 0,05). IL-10 berkorelasi positif dengan kadar hemoglobin (r= 0,134; p > 0,05). Terhadap parasitemia, TNF-α berkorelasi positif (r=0,036; p > 0.05), namun IL-10 berkorelasi negatif (r = -0,043 dan p>0,05). Dari penelitian ini dapat disimpulkan bahwa infeksi malaria falciparum berpengaruh terhadap peningkatan kadar sitokin TNF-α dan IL-10.Kata kunci : TNF α – IL 10 – malaria falciparumAbstractMalaria is still a universal health problem, especially in tropical countries because of its high morbidity and mortality rates. Infection by Plasmodium falciparum could result in severe symptoms or even death. Differences in pathogenesis among affected individuals are affected by many factors, and the immune system is one of them. Among substances involved in the malarial immunity is TNF-α and IL-10, produced by the body's defense system as the reaction to the parasite. The objective of this study is to find expression of TNF-α and IL-10 on falciparum malaria infection, using an explanatory cross-sectional design, involving 25 people with falciparum malaria with age ranging from 14 to 60 years. The presence of TNF-α and IL-10 wereARTIKEL PENELITIAN17analyzed using enzyme linked immunosorbent assay (ELISA), and significant values considered at p < 0.05. The results show that there are increased rate of TNF-α with average 283.10 ± 267.72 pg/ml, and increased rate of IL-10 with average 196.99 ± 131.94 pg/ml among people with falciparum malaria, while in normal circumstances they are not detected. There is a positive correlation of TNF-α with IL-10 (r=0.491; p>0.05), but negative correlation with the rate of hemoglobin (r=-0189; p>0.05). IL-10 correlated positively with the rate of hemoglobin (r=0.134; p>0.05). TNF-α is positively correlated with parasitemia (r =0.036; p>0.05), but IL-10 is negatively correlated (r =-0043 and p>0.05). The results from this study conclude that falciparum malaria infection increases of TNF-α and IL-10 cytokine.Keywords: TNF α – IL 10 – falciparum malaria
MITIGASI DAN EVAKUASI BENCANA PADA MASA PANDEMI COVID-19 BAGI MASYARAKAT PASIE NAN TIGO KOTO TANGAH KOTA PADANG Aisyah Elliyanti; Julizar Julizar; Lili Irawati; Miftah Irrahmah; Afriwardi Afriwardi; Yose Ramda Ilhami; Fika Anggraini; Rahmad Syawqi
BULETIN ILMIAH NAGARI MEMBANGUN Vol 5 No 4 (2022)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v5i4.333

Abstract

Disaster events both natural and non-natural factors such as epidemics can occur anytime and anywhere, which can affect communities and individuals. This natural or human-caused event or series of events can result in human casualties and suffering. Losses caused by disasters can be minimized or prevented if people's understanding of the disaster itself is sufficient, especially during the Covid-19 pandemic. Purpose: This activity is to conduct disaster mitigation training in the conditions of the Covid-19 pandemic for teachers at the Kanzul Ulum Islamic Boarding School, Kelurahan, in Pasie Nan Tigo, Koto Tangah District, Padang City. Activity target: the people of Pasie Nan Tigi Koto are able to carry out disaster mitigation and evacuation in the event of an earthquake followed by a tsunami, rising sea levels and waves. Method: activities in the form of lectures and exercises that begin with the distribution of masks to all participants involved in the activity, and filling out questionnaires on Covid-19 prevention and disaster management. After delivering the material, it was followed by a discussion on Covid-19 prevention, as well as drills on disaster mitigation and victim evacuation. The results of the activity were an increase in disaster mitigation and evacuation capabilities as well as an increase in participants' awareness in implementing health protocols for the prevention of Covid-19. Most of the participants' understanding of Covid-19 prevention and disaster management had increased, as evidenced by the increase in the number of correct questionnaire answers during the post-test compared to the pre-test from 50% to 80%. In addition, participants' skills have also increased regarding disaster mitigation, the implementation of evacuation techniques when a disaster occurs and how to evacuate victims when the disaster has subsided. Conclusion: Every individual left behind in a disaster-prone area needs to receive knowledge and training skills in disaster mitigation and evacuation techniques during the Covid-19 pandemic.
Earning Management Analysis: The Role of Firm Size, Leverage, Managerial Ownership and Profitability Safarida, Nanda; Lili Irawati; Safwan Kamal
J-EBIS (Jurnal Ekonomi dan Bisnis Islam) Vol 8, No 1 (2023)
Publisher : IAIN Langsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32505/j-ebis.vi0.5909

Abstract

Purpose: This study aims to determine the effect of firm size, leverage, managerial ownership, and profitability on earning management in a convenience goods company, PT. Tiga Pilar Sejahtera Food Tbk, wich is listed on the Indonesian stock exchange under the name AISA. Method: Secondary data are collected through the company’s financial statement from 2006 to 2020. The data were collected from the Indonesian Capital Market Directory (ICMD) and the Indonesian stock exchange websites. The quantitative approach was used to analyze the data. Then, the data were regressed by Ordinary Least Square estimation using Eview 12 software. Findings: Results revealed that firm size, managerial ownership, and profitability have no significance influence on earning management. However, leverage partially has a negative and significant effect on the earnings management. Meanwhile, firm size, leverage, managerial ownership, and profitability simultaneously influence earnings management of PT. Tiga Pilar Sejahtera Food Tbk significantly from 2006 to 2020 period. Research limitation: This research only uses some of the determinants of earnings management from many other factors that also have a contribution such as institutional ownership, board of commissioners, auditor reputation, etc. In addition, the use of several research objects in the form of companies engaged in the same business sector is also recommended for further research in order to obtain a more comprehensive and representative view. Practical Implication: This research has implications for the company's management considerations in making decisions to carry out earnings management. This form of intervention is ideal as long as it is carried out in accordance with accounting principles. This must be ensured so that the company's economic picture remains visible and risk management can still be carried out.
Hubungan Rasio Neutrofil Limfosit, Rasio Platelet Limfosit, dan Rasio Limfosit Monosit dengan Stadium Klinis Karsinoma Nasofaring di RSUP Dr. M. Djamil Padang Periode 2020-2022 Rahman, Rifna Alya; Rahman, Sukri; Almurdi, Almurdi; Yusri, Elfira; Meinapuri, Malinda; Irawati, Lili
Jurnal Otorinolaringologi Kepala dan Leher Indonesia Vol. 3 No. 1 (2024)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jokli.v3i1.56

Abstract

Karsinoma nasofaring merupakan penyakit kanker ke-5 tersering di Indonesia yang berkaitan dengan infeksi Virus Epsteinn-Barr. Rasio neutrofil limfosit (RNL), rasio platelet limfosit (RPL), rasio limfosit monosit (RLM) merupakan biomarker inflamasi yang dapat mewakili respon inflamasi sehingga dapat menggambarkan progresivitas kanker. Stadion klinis juga digunakan untuk menentukan progresivitas kanker. Penelitian ini bertujuan untuk mengetahui hubungan RNL, RPL, dan RLM dengan stadium klinis karsinoma nasofaring. Penelitian ini menggunakan desain penelitian cross sectional dengan menggunakan data rekam medis pasien di RSUP Dr. M. Djamil Padang. Pengambilan sampel dilakukan dengan teknik konsekutif sampling. Total sampel yang digunakan sebanyak 64 sampel. Uji statistik menggunakan uji Chi-square. Hasil penelitian ini diperoleh kasus karsinoma nasofaring lebih banyak terjadi pada jenis kelamin laki-laki (65,6%), kelompok umur 25–49 tahun dan terdiagnosis pada stadium IV A. Hasil pemeriksaan darah rutin berada pada rentang normal yaitu neutrofil (51,5 %), limfosit (76,9%), monosit (57,8%), dan trombosit (54,7%). Nilai RNL, RPL, dan RLM mengalami peningkatan yaitu RNL (85,9%), RPL (68,8%), dan RLM (50%). Hasil uji Chi-square yang diperoleh tidak ada hubungan RNL (p>0,05), RPL (p>0,05), dan RLM (p>0,05) dengan stadion klinis. Dari penelitian ini disimpulkan bahwa tidak terdapat hubungan yang signifikan antara RNL, RPL dan RLM dengan stadion klinis KNF di RSUP Dr. M. Djamil Padang.
Gambaran Asupan Makronutrien Pada Petugas Kesehatan RSUP Dr. M. Djamil Padang Dengan Indeks Massa Tubuh Obesitas Tahun 2022 Putri, Rahmi Dwi; Anggraini, Fika Tri; Lipoeto, Nur Indrawati; Desmawati, Desmawati; Irawati, Lili; Julizar, Julizar
Jurnal Ilmu Kesehatan Indonesia Vol. 5 No. 4 (2024): Desember 2024
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v5i4.1310

Abstract

Latar Belakang: Kejadian obesitas terus meningkat dari tahun ke tahun termasuk pada kategori pekerjaan petugas kesehatan. Salah satu faktor penyebab obesitas adalah adanya peningkatan asupan nutrisi dan penurunan aktivitas fisik. Objektif: Penelitian ini bertujuan untuk mengetahui gambaran asupan makronutrien pada petugas kesehatan RSUP Dr. M. Djamil Padang dengan IMT obesitas. Metode: Penelitian ini menggunakan metode deskriptif dengan desain penelitian cross sectional study pada data sekunder penelitian pengembangan diet terhadap petugas kesehatan RSUP Dr. M. Djamil Padang yang obesitas dengan subjek penelitian 40 responden yang diambil dengan teknik total sampling. Data IMT diukur dengan metode antropometrik dan data asupan makronutrien menggunakan food recall 2x24 jam. Analisis data menggunakan analisis univariat. Hasil: Hasil penelitian didapatkan rerata asupan energi, karbohidrat, protein, dan lemak petugas kesehatan RSUP Dr.M. Djamil Padang dengan kategori obesitas 1 secara berurutan adalah 1796,6 kkal/hari, 158,4 gr/hari, 58,44 gr/hari, dan 58,50 g/hari. Untuk rerata asupan asupan energi, karbohidrat, protein, dan lemak pada kategori obesitas 2 secara berurutan adalah 1473,92 kkal/hari, 224,35 gr/hari, 64,12 gr/hari, dan 60,60 g/hari. Kesimpulan: Kesimpulan penelitian ini adalah gambaran asupan energi dan makronutrien (karbohidrat, protein dan lemak) pada kategori obesitas 2 lebih tinggi dibandingkan kategori obesitas 1.
HUBUNGAN DERAJAT KEPARAHAN COVID-19 DENGAN FUNGSI PARU PADA PENYINTAS COVID-19 DI FAKULTAS KEDOKTERAN UNIVERSITAS ANDALAS Prasetio, Ade; Anggraini, Fika Tri; Fadrian; Irawati, Lili; Anggrainy, Fenty; Alioes, Yustini
SINERGI : Jurnal Riset Ilmiah Vol. 2 No. 4 (2025): SINERGI : Jurnal Riset Ilmiah, April 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/sinergi.v2i4.1102

Abstract

COVID-19 telah menginfeksi banyak orang di seluruh dunia selama beberapa tahun terakhir. Virus ini terutama menargetkan sistem pernapasan dan membuat para penyintasnya berisiko mengalami efek jangka panjang setelah sembuh. Penelitian ini bertujuan untuk menentukan hubungan antara tingkat keparahan klinis COVID-19 dengan fungsi paru-paru pada penyintasnya. Spirometer berbasis PC digunakan untuk memeriksa fungsi paru pada penyintas COVID-19 ringan hingga sedang di Fakultas Kedokteran Universitas Andalas. Mayoritas penyintas COVID-19 di Fakultas Kedokteran Universitas Andalas memiliki tingkat keparahan klinis ringan (86,5%). Parameter spirometri yang mengalami penurunan paling banyak adalah VEP1 (16,2%), dan mayoritas penyintas COVID-19 memiliki fungsi paru yang normal (89,2%). Fungsi paru pada penyintas COVID-19 memiliki hubungan yang signifikan dengan keparahan klinis, yang dibuktikan dengan nilai p sebesar 0,005 (p < 0,05) pada uji Fisher exact. Terdapat hubungan antara tingkat keparahan klinis riwayat COVID-19 dengan fungsi paru pada penyintas, sehingga perlu dilakukan tindak lanjut pada pasien COVID-19 setelah dinyatakan sembuh dan diperlukan penatalaksanaan lebih lanjut pada pasien yang mengalami penurunan fungsi paru
Characteristics of Patients with Thoracolumbar Fractures at Dr. M. Djamil Padang Central General Hospital in 2018-2022 Shafira, Zahra; Sahputra, Roni Eka; Noer, Mustafa; Rahmadian, Rizki; Burhan, Ida Rahmah; Irawati, Lili
(JOINTS) Journal Orthopaedi and Traumatology Surabaya Vol. 14 No. 1 (2025): April 2025
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/joints.v14i1.2025.1-9

Abstract

Background: Vertebral fracture is one of the traumas that results in the highest rates of disability and death. Vertebral fractures can occur in various regions, but more than 50% of cases occur in the thoracolumbar region T10-L2. This can be caused by several factors, such as age, gender, and BMI. More than 30% of patients have symptoms of chronic back pain accompanied by neurological deficits. This study discussed the characteristics of patients with thoracolumbar fractures at Dr. M. Djamil Padang Central General Hospital. Methods: This research is an observational descriptive study with a cross-sectional design. Research data were obtained from patient medical records, and the total inclusion sample is 139 patients with thoracolumbar fracture at Dr. M. Djamil Padang Central General Hospital in the 2018-2022 period. The data were processed and displayed as frequency distributions. Results: This research showed that the incidence of thoracolumbar fractures is found in 72 patients, with 72 being women. Mainly occurred between 15-64 years of age (73.4%), with 61.2% of cases caused by low energy trauma. As many as 62.6% of the patients received conservative management accompanied by surgery. Conclusion: This study concluded that thoracolumbar fractures often occur in women of reproductive age. The most common etiology is a fall from a height of less than three meters.
HUBUNGAN STADIUM CHRONIC KIDNEY DISEASE DENGAN HIPERTENSI PADA PASIEN CKD DEWASA DI RSUP DR. M. DJAMIL PADANG TAHUN 2020-2021. Putri, Viona Salsabila; Miro, Saptino; Irawati, Lili; Fadrian, Fadrian; Hamdani, Rita; Rasyid, Rosfita
EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan Vol. 2 No. 3 (2025): EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan, September 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/empiris.v2i3.1845

Abstract

Chronic Kidney Disease (CKD) is a condition where there is structural or functional damage to the kidneys for more than 3 months with or without being followed by a decrease in the estimated Glomerular Filtration Rate (eGFR) and is progressive and irreversible. Hypertension is the most common comorbidity found in patients with CKD which can increase the progression of kidney damage. Objective: To determine the relationship between the stage of CKD and hypertension and the distribution of the frequency of patients with CKD based on age, sex, eGFR value, and hypertension. Methods: This research was an observational analytic study with a cross-sectional design. The research was conducted at the Medical Record Installation of RSUP Dr. M. Djamil from December 2022 - March 2023 used a purposive sampling technique and obtained 33 samples. The research data was secondary data in the form of blood pressure and serum creatinine and then analyzed using the Chi-Square test with a degree of confidence of 95% and p-value <0,05. Results: This study showed that most cases of CKD occurred in the age group 41-65 years (54,5%) and mostly found in men (57,6%). In this study, stage 5 CKD was the most common (72,7%) and the majority of patients with CKD suffered from hypertension (69,7%). The results of data analysis obtained p = 0,090 (p> 0.05). Conclusion: There was no significant relationship between the stage of CKD and hypertension (P=0,090) in adult patients at Dr. M. Djamil Padang in 2020–2021.