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Fitri Kurniawati
Fakultas Ekonomi dan Bisnis Universitas Udayana, Bali, Indonesia
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Journal : Science and Technology Indonesia

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Extraction Optimization of Phenolic Compounds from Rimpang Lempuyang Gajah (Z. Zerumbet): Green Solvent (NADES-UAE) (Ultrasound-Assisted Extraction) and MAE (Microwave Assisted Extraction) Berghuis, Nila Tanyela; Nursanto, Eduardus Budi; Nanda, Elsa Vera; Maryana, Erma; Tjokrokusuma, Donowati; Kurniawati, Fitri
Science and Technology Indonesia Vol. 10 No. 4 (2025): October
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2025.10.4.1179-1187

Abstract

The Lempuyang plant is one of the medicinal plants in Indonesia. One of the plants of the Lempuyang family that has not been widely researched is Lempuyang Gajah Zingiber zerumbet (L.). The commonly used method of extraction of phenolic compounds is maceration with organic solvents. The disadvantages are the amount of organic solvents that must be used and the long extraction time (days). An environmentally friendly solvent that has been successfully developed in the 21st century is eutectic or known as Natural deep eutectic solvent (NADES). In addition, NADES can also be used in conjunction with other extraction methods such as (UAE), and microwave aid (MAE). The results obtained were the synthesis of NADES with HBA (Choline Chloride) and HBD variations (Glucose, Lactic Acid, and Ethylene Glycol) with ratios of 1:1 and 1:2. In the maceration process, variations in time (2, 4, 6 hours) and variations in extraction methods (maceration, UAE and UAE-MAE) are carried out. The best TFC (Total Flavonoid Content) value data was obtained by NADES D (choline chloride: glycerol 1:2) of 697.24 mg QE/g extract through a combined ultrasonic and microwave method (UAE-MAE) while the best TPC (Total Phenolic Content) was NADES C (choline chloride: glycerol 1:1) of 2491.88 mg GA/g extract through a combined ultrasonic and microwave method (UAE-MAE). Meanwhile, the characterization of NADES synthesis to see the interaction of hydrogen bonds through FTIR analysis, and the content of phenolic compounds and flavonoids was carried out through HPLC-DAD.
Co-Authors Ade Gunawan Aditya Hani Adnan Ahmed Usmani, Sheikh Agus Riyanto Al Rajab, Muhammad Anak Agung Ayu Suresmiathi D., Anak Agung Ayu Andi Sukendro Andilah, Sultan Andri Soemitra Atmaja, Muhammad Bima Aulia, Fira Berghuis, Nila Tanyela DIAN LATIFAH, DIAN Dimas Deworo Puruhito, Dimas Deworo Dzikriansyah, Alief fikri Eduardus Budi Nursanto Eko Pujiono Elis Nina Herliyana Erianto Indra Putra Fadillah, Febriana Eka Fajar Kurniawan Fatchan, Fuad Hudya Furqon, Imahda Khoiri Hafsah, Sariyah Hanum, Tri Arfa Harun, Marheni Fadilah Hasiu, Teti Susliyanti Hasiu Hasmita, Hasmita Herningtyas, Wieke Humaida, Nida Hutami, Rosi Ibnu Pratikto Ihsan, Adi Muhammad Nur Imahda Khoiri Furqon Iqbal Maulana Ira Nurmala Iryadi, Rajif ISMAYANTIKA DYAH PUSPASARI, ISMAYANTIKA DYAH Ismiasih, Ismiasih Isnaini Harahap Kurniawan, M. Fakih L. Lisnawati Laras Sitoayu Lestari, Agustina Ayu Listiyani, Listiyani Marbun, Wika Srihartati Maryana, Erma Mochamad Yusuf Alsagaff Muhammad Sodikin Munsir, Noviani Musyarofah Zuhri Nabawiah, Safira Nafiah, Riska Ilma Nanda, Elsa Vera Nasrun, Efa Kelya Nasrun Natasya Stifani Noor Rachmadiyanto, Arief Noviady, Ikhsan Novitasari, Deltari Nurjanah, Danik Nurmulia, Rahmi Nurnafilah, Hikmahtian Nurwahidin Purnama, Andika Purwandari, Istiti Rachmanida Nuzrina Rania, Rania Fatrizza Pritami Reni Setyo Wahyuningtyas Reza Pamunca, Airres Rina Trisnawati Saputra, Muhammad Hadi Saputra, Wiwin Savila, Lisna Nisa Sri Wahyuni, Devi Suhendri, Yudi Sukmawati, Jalma Giring SUTOMO Tafonao, Sarti Oberlian Tawakal, Tawakal Tjokrokusuma, Donowati Tri Endar Suswatiningsih, Tri Endar Vitria Melani, Vitria Wahab, Luthfi Wahyuni, Yulia Widianingsih Widianingsih Widyastika, Della