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Journal : Lontara: Journal of Health Science and Technology

Gambaran Kadar Serum Glutamic Pyruvic Transaminase (SGPT) Pada Penderita Tuberculosis Pengobatan 6 Bulan – 1 Tahun Wa Ode Rustiah; Muawanah Muawanah; Rahmawati Rahmawati; Nurul Ni’ma Azis; Novita Rahman
Lontara Journal of Health Science and Technology Vol 3 No 2 (2022): Ilmu dan Teknologi Kesehatan
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Politeknik Kesehatan Muhammadiyah Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53861/lontarariset.v3i2.300

Abstract

Tuberculosis (TB) is an infectious disease caused by the bacteria of Mycobacterium tuberculosis. A person who has been diagnosed with active TB (TB that affects the lungs and causes symptoms of coughing up blood, night sweats, weight loss, fever and chest pain), will be given a TB drug package (OAT) that must be taken for six months, where This drug is a combination of several antibiotics. TB treatment is divided into 2 phases, namely the intensive phase (2-3 months) and the continuation phase (4-6 months). The combination of drugs used consists of a combination of the main and additional drugs. In the treatment of TB, OAT is the main type of drug used. The most serious side effect of using OAT is hepatotoxic. Hepatotoxicity is a reaction to exposure to substances that can cause liver damage. Liver function tests can be done through the SGPT test. The type of this research is descriptive, with the aim of providing an overview of the results of determining Serum Glutamic Pyruvic Transaminase (SGPT) levels in TB patients who undergo treatment for 6 months - 1 year, by taking 8 samples of serum from TB patients, using the Kinetic method on the Biochemical Photometer BC153. The results showed that there were 3 samples that had increased levels of SGPT and the other 5 samples did not experience an increase in levels of SGPT (normal). Giving OAT does not significantly cause SGPT levels in tuberculosis patients to increase, but long-term administration of OAT can affect the increase in SGPT in tuberculosis patients.
Analisis Kualitatif Pewarna Rhodamin B Pada Terasi Dengan Metode Kromatografi Lapis Tipis Muawanah Muawanah; Dewi Arisanti; Abdul Razak; Nur Qadri Rasyid
Lontara Journal of Health Science and Technology Vol 4 No 1 (2023): Ilmu dan Teknologi Kesehatan
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Politeknik Kesehatan Muhammadiyah Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53861/lontarariset.v4i1.329

Abstract

Shrimp paste is one of the fishery products obtained by a fermentation process, and the main ingredients are both small shrimp and fish. In the production of shrimp paste, traders sometimes add prohibited dyes such as rhodamin B, according to the Minister of Health of the Republic of Indonesia, Number 239/Menkes/Per/V/85, because it is a synthetic dye for paper, textiles, and ink. Rhodamin B can cause liver function disorders and cause cancer. When used in food products. This study aims to determine the presence of rhodamin B dye in shrimp paste. The sampling technique was purposive sampling, with a total of 10 samples. This study conducted a qualitative analysis of rhodamin B dye using the Thin Layer Chromatography (TLC) method. Based on the results of the study, 10 samples were obtained, namely 6 positive shrimp paste samples containing rhodamin B dye, as seen based on the stains and Rf value of the sample and the rhodamin B standard. It can be concluded that most of the shrimp paste samples contain rhodamine B dye.
Gambaran Kadar Serum Glutamic Pyruvic Transaminase (SGPT) pada Penderita Demam Tifoid Wa Ode Rustiah; Rahmawati Rahmawati; Muawanah Muawanah; Dewi Arisanti; Fira Al Munawwarah
Lontara Journal of Health Science and Technology Vol 4 No 1 (2023): Ilmu dan Teknologi Kesehatan
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Politeknik Kesehatan Muhammadiyah Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53861/lontarariset.v4i1.353

Abstract

Typhoid fever is an acute systemic disease caused by the bacterium Salmonella typhi. Salmonella typhi found in the small intestine will multiply and then produce endotoxin, where the endotoxin produced is a lipopolysaccharide complex and is considered to play a key role in the pathogenesis of typhoid fever. If it enters the body, it will cause the body's condition to become weak, making it easier for Salmonella typhi bacteria to attack body tissues such as the liver and cause SGPT levels to increase. Liver damage in patients with typhoid fever in the form of changes in hepatomegaly, jaundice, biochemical, and histopathological changes. This study aims to provide an overview of Serum Glutamic Pyruvic Transaminase (SGPT) levels in patients with typhoid fever at Haji General Hospital, Makassar City. The method in this study was descriptive, with a sample population of 10 typhoid fever patients. The sampling technique used is Random Sampling. From a study conducted on 10 samples of typhoid fever patients, it was found that 6 samples had normal SGPT levels, and 4 samples had high SGPT levels, with the highest level being 95.2 µl and the lowest level being 15.9 µl. It can be concluded that the increased levels of SGPT in patients with typhoid fever is due to strenuous physical activity and taking certain drugs which can trigger increased levels of SGPT.
Identifikasi Karbon Monoksida Dalam Darah Pekerja Bengkel Sepeda Motor Rahmawati Rahmawati; Muawanah Muawanah; Waode Rustiah; Sriyunanda Laki
Lontara Journal of Health Science and Technology Vol 4 No 2 (2023): Ilmu dan Teknologi Kesehatan
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Politeknik Kesehatan Muhammadiyah Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53861/lontarariset.v4i2.384

Abstract

Air pollution is the presence of pollutant materials in the atmosphere which in certain concentrations will disrupt the dynamic balance of the atmosphere and have an effect on humans and the environment. One of the air pollutant gases is carbon monoxide (CO), which is a colorless, odorless, tasteless, non-irritating, flammable and highly toxic gas, and does not dissolve in water. Motorcycle repair shop workers are very vulnerable to exposure to CO gas while at work. The purpose of this study was to identify carbon monoxide in the blood of motorbike repair workers in Mamajang sub-district, Makassar city. This type of research is laboratory observation, namely research carried out based on direct observation. The results of research conducted using the formalin test method obtained negative results in 10 samples marked by the formation of brown coagulate in a porcelain cup. It can be concluded that 10 samples were negative or below 25% saturation.
Analisis Kadar Timbal (Pb) pada Minyak Goreng Berulang oleh Pedagang Gorengan Wa Ode Rustiah; Anita Anita; Dewi Arisanti; Muawanah Muawanah; Mirnawati Mirnawati
Lontara Journal of Health Science and Technology Vol 5 No 1 (2024): Ilmu dan Teknologi Kesehatan
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Politeknik Kesehatan Muhammadiyah Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53861/lontarariset.v5i1.429

Abstract

People have a lifestyle that tends to involve consuming junk food. Fried food is popular among the public because it is fast to serve and easy to obtain. However, the public is less aware of the safety level of fried food sold on the roadside, including fried food sellers' repeated use of cooking oil. Fried food sellers generally operate on the side of the road, where it is highly likely that lead metal (Pb) from dust particles and fumes from passing vehicles will settle in the frying pans and finished fritters. This research aims to determine the levels of Pb in cooking oil repeatedly used by fried food traders around the Muhammadiyah Makassar Health Polytechnic campus. The study was conducted as a laboratory experiment by collecting 10 samples of cooking oil repeatedly used by fried food traders. Based on the results of qualitative tests using the color reaction test method with 10% K2CrO4, 3 samples tested positive while 7 samples tested negative. Subsequently, a quantitative test was conducted by analyzing the Pb levels using the Atomic Absorption Spectrophotometry method. The levels obtained were 0.1317 mg/kg for sample B, 0.2163 mg/kg for sample H, and 0.1589 mg/kg. The maximum allowable limit for lead (Pb) contamination, as stipulated in the Regulation of the Head of BPOM RI No. HK.00.06.1.52.4011 of 2009, is 0.1 mg/kg. Therefore, it can be concluded that cooking oil for frying on the roadside around the Muhammadiyah Makassar Health Polytechnic campus, when repeatedly used, can lead to increased levels of lead (Pb), as evidenced by 3 samples exceeding the maximum allowable limit.
Co-Authors A. Salim, Indra Permata Abd. Rasyid Syamsuri Abdul Razak Abdul Razak Ahmad Jauhar Fuad Ajeng Titah Normawati Al Munawwarah, Fira Aliya, Nafisatul Amiro, Tri Andi Fatmawati Andi Fatmawati Andriansyah Andriansyah Anggraeni, Yuniar Nanda Anita Anita Anita Anita Anita Anita Arisanti, Dewi Arisyahidin, Arisyahidin Asdar, Ahsanul Khair Asmoro, Fendik Azis, Nurul Ni’ma Basarang, Mujahidah Dabur, Klaudia Sartika Dewi Arisanti Dewi, Tyas Nurmaya Diah Syifaul A'yuni Diana Nur Sholihah Endah Kinarya Palupi Epi Saptaningrum Faisal Faisal Fira Al Munawwarah Hasan Said Tortop Hasma , Hasma Hasnah Hasnah HERU PURNOMO Heru Purnomo Idayati, Nurul Indrati, Joeli Iyonu, Indriany Jasman, Henra Khoirul Sofyan Kiki Putri Amelia Laki, Sriyunanda Lala Nining Indrawati Lesmana, Utami Ayu Mirnawati Mirnawati Mirnawati Mirnawati Mudhofar, Muhamad Nor Mudinillah, Adam Muhamad Syazali Muharram, Andi Fatmawati Musa, Bilkis Nafi’ah, Umi Nana Hendracipta NILA DWI SUSANTI Novita Rahman Nur Qadri Rasyid Nurhidayat Nurhidayat Nurul Ni’ma Azis Nurul Ni’ma Azis Pambayun S Uripno Prastiwi Djamaluddin, Indra Rahmawati Rahmawati Rahmawati, Rahmawati Rasyid, Nur Qadri rika septianingsih Risnawaty Alyah Riyani, Setia Rofiqul Umam Rosyid, Muhammad Abdul Rustiah, Wa Ode Sasanti Sih Subekti Setiawan, M. Lutfi Siti Maghfirotun Amin Solikhah, Mar’atus Sriyunanda Laki suardi suardi Subroto, Desty Endrawati Suhardono Suhardono Sumardji Sumardji Sundari Sundari Surati, Tista Maya Susetiyo, Ari Susi Susanti Syahfitri Purnama Syamsul Huda Teguh Supriyanto Trian Pamungkas Alamsyah Triyono, Agung Tuty Widyanti Usman Umar Widyanti, Tuty Zuana, Muhammad Mujtaba Mitra