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Journal : inovasia

Formulation and Evaluation of Physical Properties of Antioxidant Effervescent Granules and Extract of Karamunting Flower (Melastoma malabathricum L.) Shesanthi Citrariana; Yahya Febrianto; Thathit Suprayogi; Emma Ayudia Noriadita
INOVASIA Vol 2 No 2 (2024): April
Publisher : LPPM Institut Studi Islam Sunan Doe

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58330/inovasia.v2i2.359

Abstract

Karamunting (Melastoma malabathricum L.) contains several compounds with pharmacological activities including antioxidant, analgesic, anti-inflammatory, antipyretic and diuretic. Karamunting flowers contain flavonoid compounds, saponins and tannins. Tannin compounds can stabilize free radicals by complementing the electron deficiency of free radicals. To increase the utilization of karamunting flowers, it is formulated in the form of effervescent granules. This study aims to determine the ethanol extract of karamunting flower (Melastoma malabathricum L.) with concentrations of 1%, 2%, and 3% can be formulated in the form of effervescent granules. The physical properties of the granules were tested which included organoleptic test, flow rate test, granule compressibility test, dissolving time test and pH of effervescent granules. The results showed that formula 3 with a concentration ratio of 3% ethanol extract was a formula that met the requirements for the physical properties of the granules, namely with a sweet and sour taste, a characteristic odor of karamunting, and a dark purple-brown color. With an average flow rate of 2.853 g/sec, average compressibility of 21.12%, an average dissolving time of 7.52 seconds and a pH measurement of 5.
Formulation and Evaluation of Physical Properties of Antioxidant Effervescent Granules and Extract of Karamunting Flower (Melastoma malabathricum L.) Shesanthi Citrariana; Yahya Febrianto; Thathit Suprayogi; Emma Ayudia Noriadita
INOVASIA Vol 2 No 1 (2024): April
Publisher : LPPM Institut Studi Islam Sunan Doe

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58330/inovasia.v2i2.359

Abstract

Karamunting (Melastoma malabathricum L.) contains several compounds with pharmacological activities including antioxidant, analgesic, anti-inflammatory, antipyretic and diuretic. Karamunting flowers contain flavonoid compounds, saponins and tannins. Tannin compounds can stabilize free radicals by complementing the electron deficiency of free radicals. To increase the utilization of karamunting flowers, it is formulated in the form of effervescent granules. This study aims to determine the ethanol extract of karamunting flower (Melastoma malabathricum L.) with concentrations of 1%, 2%, and 3% can be formulated in the form of effervescent granules. The physical properties of the granules were tested which included organoleptic test, flow rate test, granule compressibility test, dissolving time test and pH of effervescent granules. The results showed that formula 3 with a concentration ratio of 3% ethanol extract was a formula that met the requirements for the physical properties of the granules, namely with a sweet and sour taste, a characteristic odor of karamunting, and a dark purple-brown color. With an average flow rate of 2.853 g/sec, average compressibility of 21.12%, an average dissolving time of 7.52 seconds and a pH measurement of 5.
Co-Authors Abdul Kariem Arof Adi Wiratno, Adi Adi, Mika Adventus Panda Agista, Wida Puteri Agung Samudra Ahmad Muammar Kadafi Ahmad Taufiq Alfanaar, Rockiy Alfanaar, Rokiy Anggraeni Putri Esterlita Anisa Rahma Fauziah Ansori Rahman Ansori Rahman Arif Budianto Arif Hidayat Arsana, Mu afa Awalul Fatiqin Awalul Fatiqin Awalul Fatiqin Awalul Fatiqin Ayu, Regina Wahyudyah Sonata Ayuchecaria, Noverda Citrariana, Shesanthi Citrariana, Shesanti Decenly Decenly Decenly, Decenly Defilia Anogra Riani Desindria, Galang Rizdho Dewi, Apriana Dina Maftuha Dita Monita Elon Jipasca Emma Ayudia Noriadita Ety Kurniati Fatiqin, Awalul Fauziah, Anisa Rahma Febri Nur Ngazizah Febri Nur Ngazizah Frans Putra Ganesa Franz June Navirius Galang Rizdho Desindria Gunawan, Yohanes Edy I Nyoman, Sudyana, Ike Apriani Indah Gumilang Dwinanda Jenny Blessia Gerung Jessica Alexandra Roselia Jipasca, Elon Kadek Ayu Cintya Adelia Kamison Karyadi Karyadi Karyadi Karyadi Kormil Saputra Kurniawan, Yehezkiel Steven Kurniawidi, Dian W. Mariasa, Joice Cleriska Markus Diantoro Marlina, Resti Mika Adi Saputra Monita, Dita Mu'afa Purwa Arsana Muhamad Taufik Hidayat Muhammad Baqir Zaini Muhammad Hasanul Haq Muhammad Hudan Rahmat Muhammad Priyadi Muhammad Rifqi Shodri Murwantini, Sri Mu’afa Purwa Arsana Nathanael Neda Galeno Ngazizah, Febri Nur Norhusna, Norhusna Nur Amirah Mat Nor Nur Hidayat Okta Meilawaty Parametta, Vidya Putri Wineni Ra Hoetari Tirta Amelia Rahman, Sudarman Regina Wahyudyah Sonata Ayu Renna Jessica Sihombing Riana, Shesanti Citra Riani, Defilia Riri Novita Sunarti Risfa Aliya Al-Hadi Rizki Rachmad Saputra Rokiy Alfanaar Rokiy Alfanaar Rokiy Alfanaar S E I Suryani S W Himmah Sahari, Yudhi Ekakristian Samsul Arifin Samuel Layang Sandi Mahesa Yudhantara Shahan Shah Shesanthi Citrariana Shesanti Citra Riana Shesanti Citra Riana Shesanti Citrariana Shodri, Muhammad Rifqi Simajuntak, Ruth Riama Siti Maryam Siti Sunariyati Solehudin Solehudin Sulistia, Tiya Sunaryono Susi Rahayu Syarifah Syarifah Titik Istirohah Wilda, Robiatul Witari Yahya Febrianto Yahya Febrianto Yahya Febrianto Yahya Febrianto Yahya Febrianto Yahya Febrianto Yithro Serang Yohanes Edi Gunawan Yohanes Edy Gunawan Yosaeunike, Vitatani Yudhi Ekakristian Sahari Yulita, Elia Z Nurdiana ZAINUL ARIFIN IMAM SUPARDI