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All Journal Dentika Dental Journal Jurnal Biosains Pascasarjana Indonesian Journal of Tropical and Infectious Disease ODONTO Dental Journal Jurnal Penelitian Pendidikan Dental Journal (Majalah Kedokteran Gigi) Padjadjaran Journal of Dentistry Jurnal Akuntansi dan Pajak Indonesian Journal of Chemistry Indonesian Journal of Dental Medicine Berkala Penelitian Hayati Odonto dental journal Bhakta Dental Journal Kurva: Jurnal Ekonomi Manajemen Keuangan dan Bisnis
Retno Pudji Rahayu
Department Of Oral Pathology And Maxillofacial, Faculty Of Dental Medicine, Universitas Airlangga
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences

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Analysis of antioxidant and antibacterial activity of cocoa pod husk extract (Theobroma cacao L.) Rahayu, Yani Corvianindya; Setiawatie, Ernie Maduratna; Rahayu, Retno Pudji; Ramadan, Doaa Elsayed
Dental Journal (Majalah Kedokteran Gigi) Vol. 56 No. 4 (2023): December
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i4.p220-225

Abstract

Background: Theobroma cacao bean manufacturing worldwide includes undesired byproducts such as cocoa pod husks. Cocoa pods contain a variety of beneficial chemicals, including polyphenols. Polyphenols have a vital function in the treatment of many illnesses and infections of the oral cavity. This is due to their vital qualities in the oral cavity, including anti-inflammatory, antibacterial, and antioxidant actions. Purpose: The goal of this study was to look at the antioxidant content and antibacterial activity of cocoa pod husk extract (Theobroma cacao L.) against Phorphyromonas gingivalis (P. gingivalis) and Streptococcus mutans (S. mutans). Methods: Cocoa pod husk extract was produced using an ultrasonic homogenizer and 70% ethanol. Thin layer chromatography and the Folin–Ciocalteu test were used to determine the phytochemical content and total phenolic content of the extract. The 2,2-diphenyl-1-picryl-hydrazyl-hydrate technique was used to measure antioxidant activity. Minimum inhibitory concentration (MIC) tests were used to measure the antibacterial activity of ethanolic extract at concentrations of 1, 4, 8, 16, 32, and 64 mg/ml using a deep-well broth microdilution technique. Results: The presence of alkaloids, flavonoids, tannins, saponins, and triterpenoids was discovered in the cocoa pod husk extract. Conclusion: The antioxidant activity of the extract was significant (IC50 = 62 ppm), and the MIC of P. gingivalis and S. mutans was 16 mg/ml and 8 mg/ml, respectively.
Co-Authors - UBSI Karawang, Djulaeha A. Toto Purnomo Achmad Ardianto, Achmad Adiana Mutamsari Witaningrum Adiana Mutamsari, Adiana Agung Sosiawan Aisah Faiz Bachmid Amir, Muhammad Subhan Aqsa Sjuhada Oki Ardyni Febri K Azhar, Imam Safari Banerjee, Abhishek Basalamah, Fatimah F. Bhagat, James Antony Bimo Dwi Lukito, Bimo Dwi Budi Utomo Caesario, Jefferson Chaterina Dyah Nanik Kusumawardani Christian Khoswanto, Christian Cinantya, Aulia Dian Danoediningrat, Coen Pramono David B. Kamadjaja Desiana Radithia, Desiana Devi Oktaviani, Paramita Dewi Puspitasari Diah Savitri Ernawati Dian Widya Damaiyanti Djoko Agus Purwanto Elizabeth, Laurencia Dwiamanda Elly Munadziroh Ernie Maduratna Setiawatie Fadila, Okta Mulia Nur Fedik Abdul Rantam Ferdiansyah Ferdiansyah Firjani, Putri Nabila Fitria Rahmitasari Hanif, Hilmy Irsyadi Hansen Kurniawan Haryono Utomo Hening Tuti Hendarti Imannia, Ristya Sylva Indra Lila Kusuma, Indra Lila Ira Arundina Islamy, Azzahra Hasnur Juniastuti Juniastuti Kharinna Widowati Laurencia Dwiamanda Elizabeth Livesey, Gisele Nefertari Love LMS Kristiyanti, LMS Loverita, Dyta M. Qushay, M. Maharani Laillyza Apriasari Maharani, Annissaqiella Maretaningtias Dwi Ariani, Maretaningtias Dwi Maria Inge Lusida Marks, Luc A. M. Masitoh, Hindun Fitria Maulina, Syafriaz Zulfa Maya Widyana Dewi Melathi, Harum Merlynike Leo, Leviena Moch Febi Alviansyah Muhammad Luthfi Nasronudin Nasronudin Ni Putu Mira Sumarta Nugraha, Ilyas Yakob Nurul Nurina Febriyanti Ayuningtyas Nuzulistina, Elvin Pasaribu, Togu Andrie S. Pramitha, Selviana R. Pratiwi, Chandrasasi Berlian Pratiwi, Desy Nur Prihartini Widiyanti Purwaningrum, Vegananda Wahyu Puspa Dila Rohmaniar Puteri, Astari Putri, Destiana Hardianti Rahmah, Shafwa Aisha Ramadan, Doaa Elsayed Regina Purnama Dewi Iskandar Retno Indrawati Roestamadji Riskayanti, Ni Putu S.Pd. M Kes I Ketut Sudiana . Saka Winias Salsabila, Alisya Rachel sari, Rima parwati Septian Pradana, Septian Setiawan, Kresna Erlangga Shallomitha, Aginta Gracia Sisca Meida Wati Siti Qamariyah Khairunisa, Siti Qamariyah Siti Qomariyah Khairunisa, Siti Qomariyah Sri Agoes Soedjarwo Sri Hernawati Sri Wigati Mardi Mulyani Supandji, Rafaelle Raditya Surboyo, Meircurius Dwi Condro Syahdiar, Aura Zalfa Ghassani Syamsulina Revianti Tania Saskianti Theresia Indah Budhy Sulisetyawati Titiek Berniyanti Tomohiro Kotaki, Tomohiro Utari Kresnoadi Wahyu Aji Wibowo Widyasri Prananingrum Yani Corvianindya Rahayu Yanty Wirza Zafar, Anis Fatimah