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All Journal Jurnal Keperawatan Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Jurnal Kedokteran Brawijaya Prosiding Seminas Competitive Advantage Wacana, Jurnal Sosial dan Humaniora Indonesian Journal of Disability Studies Research Journal of Life Science MNJ (Malang Neurology Journal) Universa Medicina Majalah Kesehatan FKUB BIMIKI (Berkala Ilmiah Mahasiswa Ilmu Keperawatan Indonesia) JSMARTech : Journal of Smart Bioprospecting and Technology Az-Zahra: Journal of Gender and Family Studies Pharmaceutical Sciences and Research (PSR) Jurnal Ners dan Kebidanan (Journal of Ners and Midwifery)
Retty Ratnawati
Faculty of Medicine, Brawijaya University, Jl. Veteran, Malang
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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PENGARUH PERAWATAN LUKA BAKAR DERAJAT II MENGGUNAKAN EKSTRAK ETANOLDAUN SIRIH TERHADAP KETEBALAN JARINGAN GRANULASI PADA TIKUS PUTIH JANTAN Ratnawati, Retty
BIMIKI (Berkala Ilmiah Mahasiswa Ilmu Keperawatan Indonesia) Vol. 3 No. 1 (2015): Edisi Januari - Juni 2015
Publisher : Ikatan Lembaga Mahasiswa Ilmu Keperawatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (5764.306 KB) | DOI: 10.53345/bimiki.v3i1.73

Abstract

Luka bakar yang paling ditemukan adalah luka bakar derajat II.
Alterations in Blaood Profiles and Spleen Tissue Following Purple Sweet Pota-to Anthocyanin Extract Treatment in Restraint-Stressed Mice: Blood Profiles and Spleen Tissue Following Purple Sweet Potato Anthocyanin Extract Treatment Kurnianingsih, Nia; Artamevia, Dian; Hasanah, Dian; Harbiyanti, Novita Titis; Ratnawati, Retty
Journal of Tropical Life Science Vol. 14 No. 1 (2024)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.14.01.19

Abstract

Stress is associated with broad changes in blood and immune cell dysfunction, which are correlated with the spleen as a secondary lymphoid organ. Anthocyanin, a plant bioactive compound from purple sweet potatoes, has previously been reported to have a beneficial effect on stress response behavior. However, the limited studies evaluated anthocyanin's effect on blood profiles and spleen tissue under stress. Therefore, this study aimed to explore the effect of total anthocyanin extract (ANC) from purple sweet potatoes (PSP) on the blood profiles and spleen tissue of restraint stressed mice. A total of 20 male adult BALB/c mice were divided into control (CTRL), stress (STR), stress + ANC 10 mg/kgBW (STR+ANC10), stress + ANC 20 mg/kgBW (STR+ANC20), and stress + ANC 40 mg/kgBW (STR+ANC10). Restraint stress was applied two hours/day for 14 days. An automatic blood analyzer was used for blood profiling. Immunoblotting of caspase-3 and hematoxylin-eosin-stained histological slides were observed for spleen tissue analysis. Combination of STR and ANC treatment reduced the erythrocyte count, hemoglobin level, and leucocyte count. The ANC-treated groups had a higher percentage of lymphocytes and a lower percentage of granulocytes. The expression of caspase-3 declined among ANC-treated groups. Spleen extramedullary erythropoiesis, vacuolization, and white pulp involution were demonstrated in stress and ANC-treated animals. In summary, restraint stress modified the blood cell profiles and spleen tissue in the mice model. Further research is necessary to evaluate the mechanism of ANC during stress on blood cells and splenic tissue repair enhancement.
Co-Authors A.A. Ketut Agung Cahyawan W AA Sudharmawan, AA Almira, Nabila Sella Anak Agung Gede Sugianthara Analis W Wardhana Anastasia Novitasari, Anastasia Annisa Nurul Arofah Annisa' Wigati Rozifa Ardani Galih Prakosa, Ardani Galih Artamevia, Dian Arum Desi Pratiwi, Arum Desi Atma Gunawan Aulanni'am, Aulanni'am Cahayani, Wike Astrid Christian Julio Suhardi, Christian Julio Darwatik, Darwatik Dian Hasanah Dian Susmarini, Dian Diana Lyrawati Dina Dewi SLI Eviana Norahmawati Fahanani, Agwin Fahmi Faridha Khaira H Fauzi Ahmad Muda Ferdina, Cucun Setya Harbiyanti, Novita Titis HARI PURNOMO Heri Kristianto Herin Mawarti Hery Wibowo Hidayat Sujuti Ika Subekti Wulandari, Ika Subekti Ikhda Ulya, Ikhda Inggita Kusumastuty Intan Berlian, Intan Irawan, Dwi Dianita Kenty Wantri Anita, Kenty Wantri Kumboyono Kumboyono Kumboyono, K Kurnianingsih, Nia Lilik Supriyati, Lilik Lilik Wahyuni Lisa Aulia, Lisa Made Ayu Hariningsih, Made Ayu Masruroh Rahayu, Masruroh Mochammad Dalhar Noorma Lukitasari Nur Permatasari Nurdiana Nurdiana Pratista Adi Krisna, Pratista Adi Prayogo, Nabila Putri Purwitasari, Alief Ayu Rahma, Oktivani Adelathifa Rayhanna, Qanitha Ailsya Reza Fitra Kusuma, Reza Fitra Rinik Eko Kapti, Rinik Ririn Handayani Risma Karlina Prabawati Sartika Dewi Utami, Sartika Dewi Sarwono . Sawitri, Lia Siti Nurfitria, Siti Sri Andarini Sri Budhi Rianawati, Sri Budhi Sri Haryuni Sri Rianawati Suprapto, Ratih Paramita Tinny Endang Hernowati Titisari, Nurina Wike Wike, Wike Wiwi Jaya Yudhantara, Dearisa Surya