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All Journal JBIO: jurnal biosains (the journal of biosciences) JPKMI (Jurnal Publikasi Kesehatan Masyarakat Indonesia) JOPS (Journal Of Pharmacy and Science) Hearty : Jurnal Kesehatan Masyarakat JURNAL FARMASIMED (JFM) Jurnal Kesehatan Ilmiah Indonesia / Indonesian Health Scientific Journal Contagion: Scientific Periodical Journal of Public Health and Coastal Health Jurnal 'Aisyiyah Medika Jurnal Penelitian Farmasi dan Herbal Jurnal Kesehatan Tambusai Jurnal EduHealth Ahmar Metastasis Health Journal (AMHJ) Jurnal Kolaboratif Sains Ahmar Metakarya: Jurnal Pengabdian Masyarakat Jurnal Berita Kesehatan Jurnal Pengabdian Masyarakat Putri Hijau JRKN Sehat Rakyat: Jurnal Kesehatan Masyarakat QISTINA: Jurnal Multidisiplin Indonesia Journal of Health Sciences and Medical Development Promotor: Jurnal Mahasiswa Kesehatan Masyarakat JUKEJ: Jurnal Kesehatan Jompa
Wahyudi Wahyudi
Universitas Islam Negeri Sumatera Utara
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Journal : JURNAL FARMASIMED (JFM)

 1 
Combination Tea of Vernonia Amygdalina Del. Leaves and Syzygium Polyanthum Leaves as Complementary Therapy for Type 2 Diabetes Mellitus Wahyudi, Wahyudi; Sinaga, Haryanti; Tanjung, Hazira Yulistia
Jurnal FARMASIMED (JFM) Vol 7 No 1 (2024): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i1.2303

Abstract

Type 2 diabetes mellitus (T2DM) is a global health problem that increase every year. This study aims to test the effectiveness of a combination of African leaf and bay leaf tea as a complementary therapy for type 2 diabetes mellitus (TEDAS). This experimental research used mice induced with alloxan. Treatment and observation of antidiabetic effects were carried out for 12 days of treatment and KGD was measured every 3 days. There were 6 test groups including positive control using glibenclamide, negative control, no treatment, TEDAS1, TEDAS2 and TEDAS3. Phytochemical screening shows that TEDAS contains secondary metabolite compounds including tannins, alkaloids, flavonoids and saponins. The results showed that all TEDAS groups significantly reduced blood glucose levels. KGD examination on day 12 showed that the KGD in the group without treatment was 87, negative control 126 mg/dL, positive control 90 mg/dL, TEDASI 95 mg/dL, TEDAS2 91 mg/dL, and TEDAS3 96 mg/dL. The most effective group is TEDAS2 with glibenclamide + DA 100mg/Kgbb + DS 50mg/Kgbb treatment. Research indicates that TEDAS is effective as a complementary therapy for T2DM.
Co-Authors Ade Risma Adelia, Nelsih Aguansyah Maulana Siregar Aisa Maharani Hasibuan Alya Alfianti Balqis Alya Najwa Amalia Rahmi Nasution Amelia Putri Amanda Nasution Aminuyati Ana Firda A'Qila Andhani, Intan Angkat, Chairunissa T. D. E. Asghoriah, Azinatul Aulia, Dinda R. Azizah, Najwa Azzahro, Rahmi Damayanti Azzura, Sabrina Febri Barus, Nency Utami Br Billa, Nurna BM, Bima Fadhilah Cantika, Shafira Putri Dalimunte, Syelsa Yustrina Damanik, Nazwa Ayudhia Ghani Dawamah, Nurazizah Delfi Yunita Lubis Delisma Simorangkir Simorangkir Dewi Safitri Ginting Dhea Rizky Fitri Saragi Dian Ika Perbina Meliala Faiza Adinda Fathur Rifqy, Iqbal Fatila, Nabila Fatima Fatima Feby A Putri Firdaus Fahdi Fransisca, Cintya Hasanatun Laili Hasibuan, Ade Degisqi Maharani Herviani Sari Herviani Sari Husnan Tengku, Najwa Azizah Jihan Nabila Ritonga Karfita Adha Kayla Mazril, Zahra Kemala Sari Damanaik Khairunnisa Khairunnisa Laila Sari Manurung, Jahrani Manurung, Revina Aulia Mawaddah Sri Rezeki Dalimunthe Mawandri, Dwi Medina Elly Vanda Mega Rahmadani Siregar Muhammad Jidan Al-Khoir Muhammad Ridwan Muhammad Sahputra Nabila, Nazua Nasution, Aldi Syahputra Nasution, Mutiara Natasya Putri Lika Nelva Nelva Nur Ashilah S Rkt Nurly Fadhila Nurmaulia Nurmaulia Nurul Fauziah Ode, Anggun Nabila Panggabean, Hikmah Tin Pivit Rahayu Pohan, Dhea Afriza Prahasti, Hanum Purba, Rizki Yani Puti Miratil Hayati Efri Putri, Dwi A. Rapotan Hasibuan Regita Cahyani Rini Handayani Risca Muril Khairani Riski Andriani Ritonga, Fani Rulianda Ritonga, Sela Rizqa Auliyah Shifah Sagala Sahilla, Rizka Salsabilla, Anggina Zahra Sembiring, Andini Sembiring, Andini Br Septiani Rizka Shelly Febrina Simatupang , Ahmad Shiddiq Sinaga, Haryanti Sirait, Salshabila Azzahra Siti Nurhaliza Sitio, Sri Sudewi Pratiwi Situmorang, Irsyad Baihaqi Sri Rezky Gantina Sri Wahdina Tanjung Syaira Alfauza Syifana Nadia Raisya Tanjung, Hazira Yulistia Tanjung, Putri Keza Hidayah Tanjung, Sri Wahdina Tengku Armita Chairiyah Tia Munika Vera Estefania Kaban Wahyuni , Raduwi Windi Zahrani Yasmin, Wan Yara