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Journal : Journal Research of Social Science, Economics, and Management

Potential Nano Gel Avocodo Seed Extract as an Alternative Relief in Wounds After Removal of White Rats Tooth yulistina, yulistina; Suwondo, Ari; Santoso, Bedjo
Journal Research of Social Science, Economics, and Management Vol. 2 No. 1 (2022): Journal Research of Social Science, Economics, and Management
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jrssem.v2i1.235

Abstract

Inflammation, bleeding, swelling, pain, dry socket are common complications of tooth extraction. The inflammatory response is divided into two, including the administration of non-steroidal anti-inflammatory drugs (NSAIDs) and steroid anti-inflammatory drugs. Every use of chemical drugs has side effects. Herbal ingredients are needed, namely avocado seeds as an alternative treatment in preventing inflammation in wounds after tooth extraction. Avocado seeds contain polyphenols that play a role in inflammation in wounds, including flavonoids, alkaloids, tannins, and saponins. Experiment with randomized posttest design with control group design. Consisting of intervention group nano gel avocado seed extract 10%, positive control group povidone iodine 10% and aquadest. Observations were made for 7 days. The variables studied were inflammation of the wound after tooth extraction of rats and histopathological examination (Lymphocytes, Neocapillary and Fibroblasts). Based on the results of the unpaired test, the avocado and povidone groups were not significantly different (p=0.143), the avocado and aquadest groups had a significant difference (p=0.001) and the povidone and aquadest groups had a significant difference (p =0.015). The administration of nano gel of avocado seed extract with a concentration of 10% and 10% povidone iodine has the same ability in the process of wound regeneration and increases new blood vessels and can also reduce the number of lymphocyte inflammatory cells as evidenced by histological examination . The administration of nano gel of avocado seed extract is effective and can be applied as an alternative to prevent inflammation in wounds after tooth extraction in white rats.
Co-Authors Ahmaniyah, Ahmaniyah Ahmaniyah, Ahmaniyah Anak Agung Gede Sugianthara Annisa, Rifka Apriyana Irjayanti Arwani Arwani Arwani Asmawati, Lilik Astuti, Rara Sri Endang Puji Baju Widjasena Bedjo Santoso Kadri Beniqna Maharani Besmaya Bina Kurniawan Budhi R, Kamilah Daniati, Nia Daniati Darmini Darmini Daru Lestantyo Dengo, Moh. Rivandi Dessy Triana Desyandri Desyandri Deviana, Meli Dhanio, Yeyen Wulandari Diyah Fatmasari Djamil, Masrifan Dwi Cahyanti, Dwi edy susanto Ekawati Ekawati Endah Kumala Dewi Erlina Krisanti Faridah, Salsabila Nur Ferry Ardhiansyah Fitriyaningsih, Erna Indah Freya Nazera Iskandar Gatot Murti Wibowo, Gatot Murti Gunasari, Lala Foresta Valentine Gurnita, Fauziah Winda Hadisaputro, Haryo Hamdan, Yusuf Lensa Hanif, Fastabiqul Haryono, Nathasia Elga Hidajati, Kamilah Hidajati, Kamilah Hidayah, Khoirotul Hiyana TD, Christin Husna, Dewi Asmaul Krisdiana Wijayanti Kurnianingsih Kurnianingsih, Kurnianingsih Ladyvia, Fiyola Laksana, Ni'matun Faizah M. Choiroel Anwar Mardiyono Mardiyono Martini Martini Mateus Sakundarno Adi, Mateus Sakundarno Melyana Nurul Widyawati Muchlis Achsan Udji Sofro Mulya, Dimas Yuzril Nainggolan, Wiwiek Neni Susilaningsih Noor Pramono Nurharisah, Siti Nurjazuli Nurjazuli Pradesi, Regina Pranandya, Brian Ilham Pujiastuti, Rr. Sri Endang Putri, Rifa Fauziah Syaifia Rasipin Rasipin Runjati Sarwendah Dewi Astuti, Sarwendah Dewi Siswi Jayanti Siti Rizki Amalia Sofro, Muchlis AU Sri Anureksi SRI RAHAYU Sudirman Sudirman Sudiyono Sudiyono Suharyo Hadisaputro Supriyana Supriyana, Supriyana Suroto Suroto Suryati Kumorowulan Syuhada, Ambar Dani Theresia Ristadeli Tinuk Istiarti Tri Utami, Annisa Rachmah Tri Wiyatini, Tri Ulfa Nurullita Wahyuningtyas, Miranda Gita Wahyuningtyas Walin Walin, Walin Waode Fitrah Sari Yuliani Setyaningsih Yuliatri, Risa Yulisnawati Yulisnawati Yulistina Yulistina Yuni Kusmiyati Yuniarti - Yunus, Fanny Thresia