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All Journal Jurnal Ilmu Pertanian Indonesia ACTA VETERINARIA INDONESIANA Jurnal Veteriner Majalah Kedokteran Bandung Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) Buletin Farmatera ARSHI Veterinary Letters Vitek : Bidang Kedokteran Hewan Veterinary Biomedical and Clinical Journal Jurnal Kedokteran Hewan Jurnal Veteriner dan Biomedis Current Biomedicine Policy Brief Pertanian, Kelautan, dan Biosains Tropika Indonesian Journal of Jamu
Aulia Andi Mustika
Institut Pertanian Bogor
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences Veterinary

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Journal : Veterinary Biomedical and Clinical Journal

 1 
Efficacy of Shallots Infusion (Allium Cepa L.) as an Antidiarrhea in Mice (Mus Musculus) Purohita, Adwisto Saktika; Aulia Andi Mustika; Lina Noviyanti Sutardi; Fadholly, Amaq
Veterinary Biomedical and Clinical Journal Vol. 4 No. 2 (2022)
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.VetBioClinJ.2022.004.02.2

Abstract

Shallots have been used for generations as traditional medicine, one of which is used in the treatment of diarrhea. This study determined the antidiarrheal activity of the shallot bulbs using intestinal protection and intestinal transit methods, and to determine the effective concentration that gives the best antidiarrheal effect in mice. This study used thirty mice and divided into six groups. The negative control group was given Tween 80 (1%), positive control group was given Loperamide HCl, and four various concentrations of shallot infusion treatment groups (1.25%, 2.5%, 5%, and 10 %). The treatment was given by the oral route. The parameters used in the intestinal protection method were frequency of defecation and feces consistency, while in intestinal transit method the parameters used were the percentage ratio of the marker trajectories compared to the overall length of the intestine. The results showed that the 1.25% concentration of shallot infusion indicated the best antidiarrheal activity and had a smaller ratio or stronger inhibition to intestinal peristaltic compared to all other concentrations, 2.5%, 5%, dan 10%. We concluded that shallot bulbs infusion with a concentration of 1.25% has the most effective anti-diarrheal effect. This research can be continued by measurement of other diarrheal parameters such as stool weight, as well as start and stop time of diarrhea to further clarify the anti-diarrheal potential of shallot bulb infusion.
Co-Authors . andriyanto . Soeripto Adi Winarto Afiff , Usamah Aisyah Nurfitria Ayumi Alifiana Fitrianingrum Alifin Wisnu Ananta Alpayet, Rahmat Amaq Fadholly Amperanoto, Agus Amrozi Andriyanto Andriyanto . Andriyanto . Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto, Andriyanto Andriyanto Anggia Murni Wijiati Anggraeni, Henny Endah Anggraini, Lutvi Anisa Rahma, Anisa April Hari Wardhana April Hari Wardhana April Hari Wardhana Arief Sabdo Yuwono Aurelia, Sharon Bambang Pontjo Priosoeryanto Bondan Achmadi Budi Purwanto Diah Nugrahani Pristihadi Diky Yuliansah Diky Yuliansah Dodi Darmakusuma Dodi Darmakusumah Edwin Ligia Sastra Ekowati Handharyani Elpita Tarigan Elpita Tarigan Erli Chandra Esti Dhamayanti Fadiela Salima Putri Febrita, Joana Fedik Abdul Rantam Fifi Gus Dwiyanti Firda Agustin Firda Agustin Firda Agustin, Firda Hamdika Yendri Hamdika Yendri Hamdika Yendri Hamdika Yendri Putra Hudaya, Aang IBNUL QAYIM IETJE WIENTARSIH IPB, BPKB Irarang, Yusa Jusuf, Elena Adjani Kharisma Mardathilah Kharisma Mardathilah Khonsa Khonsa Kusdiantoro Muhamad Lailan Safina Nasution Leliana Nugrahaning Widi Leliana Nugrahaning Widi Leliana Nugrahaning Widi Leliana Widi Leo Sapelani Soinbala Lina Novianti Sutardi Lina Novianti Sutardi, Lina Novianti Lina Noviyanti Sutardi M. Agung Zaim Adzkiya Madyastuti, Rini Mardathilah, Kharisma Meilisa Lidya Margarita Meti Ekayani Michella Hoseana Wijaya Mohammad Miftahurrohman Muhammad Bintang Nababan, Ratna Kristiani Nabilah, Avida Shahnaz Ni Made Ria Isriyanthi Purohita, Adwisto Saktika Putra, Hamdika Yendri Putra, Heriansyah Putri, Fadiela Salima Rahmawati Januar Rahminiwati, Min Rai Sita Rendi Pratama Mukti Ridi Arif Rifnadhi, Bayu Rina Mardiana Rindy Fazni Nengsih Rindy Fazni Nengsih Risna Anggraeni Rukmana, Adi Safitri, Nadiya Santosa, Alfian Sari, Windi Mayang Silmy Kamila Widyanti Siti Saadah SM Leluala Subangkit, Mawar Sultania A Suleman Sus Derthi Widhyari Trioso Purnawarman Unang P. Upik Kesumawati Hadi Utami, Annisa Dwi Wasmen Manalu Widi, Leliana Nugrahaning Yayuk Sri Rahayu Yendri, Hamdika Yuliansah, Diky Yusa Irarang Zaenal Abidin