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All Journal Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga. Jurnal Kedokteran Muhammadiyah Mutiara Medika: Jurnal Kedokteran dan Kesehatan Biomedika Nutri-Sains: Jurnal Gizi, Pangan dan Aplikasinya Jurnal Farmasi Sains dan Komunitas Jurnal Kedokteran dan Kesehatan Herb-Medicine Journal Jurnal Kesehatan Bina Generasi Jurnal Surya Masyarakat MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan Jurnal Ilmu Kedokteran dan Kesehatan Medica Arteriana (Med-Art) Science Midwifery Jurnal Surya Masyarakat Al-Iqra Medical Journal : Jurnal Berkala Ilmiah Kedokteran Jurnal EduHealth JURNAL INOVASI DAN PENGABDIAN MASYARAKAT INDONESIA International Journal of Health and Pharmaceutical (IJHP) Ahmad Dahlan Medical Journal Jurnal Sehat Indonesia (JUSINDO) Prosiding University Research Colloquium Prosiding Seminar Kesehatan Masyarakat Prosiding Seminar Nasional Unimus
Ika Dyah Kurniati
Univeristas Muhammadiyah Semarang
Religion Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Education Engineering Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Effects of Giving Kaffir Kaffir Extract ( Citrus hystrix ) on Blood Glucose Levels in Wistar Rats Ika Dyah Kurniati; Dyah Mustika Nugraheni; Mutiara Aura Kusuma
Ahmad Dahlan Medical Journal Vol. 3 No. 2 (2022): November 2022
Publisher : Universitas Ahmad Dahlan

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Abstract

Dyslipidemia is associated with cardiovascular disease as well as hyperglycemia and insulin resistance. One of the natural ingredients for controlling dyslipidemia is kaffir lime peel ( Citrus hystrix ), which contains flavonoids and polyphenols that act as antioxidants and regulate blood glucose. This study aims to prove the effect of kaffir lime peel in lowering blood glucose levels. Methods : Post-test only controlled group design study , using 25 wistar rats divided into 5 groups, namely group (K-) without high-fat diet and extract (K+) was given a high-fat diet alone, (P1) was given kaffir lime peel extract at a dose of 35 mg/kg BW rats/day, (P2) was given extract at a dose of 70 mg/kg BW rats/day and (P3) was given extract at a dose of 140 mg. /kgBW rats/day. The intervention was given for 3 weeks and then blood glucose levels were measured using the GOD-PAP method. The data were analyzed using the Kruskal Wallis test and continued with the Mann-Whitney test. Results : The results showed a significant difference in the mean GDS levels between groups p=0.011 (p<0.05), Mann-Whitney test showed K(-) against P1 (ρ=0.009), K(-) against P2 (ρ=0.016) , K(-) to P3 (ρ=0.028), and P1 to P2 (ρ=0.028).
Antimicrobial Activity of Pecut Kuda Leaf Extract (Stachytarpheta jamaicensis (L. Vahl) against Mycobacterium smegmatis Putri Nadia Ramadhani; Ika Dyah Kurniati; Maya Dian Rakhmawatie
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 23, No 1 (2023): January
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v23i1.15599

Abstract

Mycobacterium smegmatis infrequently causes infection, but it is easy to be pathogenic in immunosuppressed patients. Many reported that M. smegmatis resistance to several antibiotics became an impetus for searching for new antimicrobials. Therefore, this study aims to prove the effect of Pecut Kuda leaf extract (Stachytarpheta jamaicensis (L.) Vahl) on the growth of M. smegmatis mc2 155. This research is an experimental study with a post-test control group design. The susceptibility test was carried out using the two-fold microdilution method and resazurin staining. The concentration of Pecut Kuda leaf ethanol extract was prepared in the concentration range of 10000.0 – 625.0 µg/ml.  Phytochemical analysis of the content of saponins, tannins, flavonoids, and alkaloids was also carried out on Pecut Kuda leaf ethanol extract. Pecut Kuda leaf ethanol extract can inhibit the growth of M. smegmatis with a minimum inhibitory concentration (MIC) of 5000 µg/ml (very weak activity) because, at the highest concentration of 10000 µg/ml, M. smegmatis still cannot be killed. Furthermore, Pecut Kuda leaf ethanol extract contains saponins, tannins, flavonoids, and alkaloids which are known to have antibacterial activity. However, further evaluation is needed to maximize the antibacterial activity of Pecut Kuda leaf extract, for example, by fractionating the extract.
Risk Factors Analysis of Diaper Dermatitis in Children Aged 0-36 Months at Puskesmas Working Area, Tembalang District Ika Dyah Kurniati; Laila Arina Hukma Adila; Retno Indrastiti
Ahmad Dahlan Medical Journal Vol. 4 No. 1 (2023): May 2023
Publisher : Universitas Ahmad Dahlan

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Abstract

Diaper dermatitis is an inflammation of the skin in the diaper area caused by contact with urine and feces and the friction of the diaper against the skin. The incidence of diaper dermatitis in Indonesia is 7-35% in male and female infants with the highest number at the age of 6-12 months. The purpose of this study was to determine the factors associated with diaper dermatitis in children aged 0-36 months at the Tembalang District Puskesmas, such as age, gender, mother's education level, mother's occupation, economic status, frequency of diaper changes, and personal hygiene. This study used an observational analytic method of Case-Control approach with a sample of 30 people, 15 case groups and 15 control groups with purposive sampling technique. Data were obtained through a questionnaire instrument which was then tested with the Chi-Square test with the help of software. Statistical test results showed no significant relationship between age, gender, mother's education level, mother's occupation, and economic status with the occurrence of diaper dermatitis and there was a significant relationship between the frequency of diaper changes 0.013 (p < 0.05) and personal hygiene 0.008 (p < 0.05). There is a significant relationship between the frequency of diaper changes and personal hygiene with the occurrence of diaper dermatitis, and there is no significant relationship with other risk factors.
Relationship of Exclusive Breastfeeding with The Incidence of Acute Respiratory Infections in Toddlers at The Ringinarum Health Center Kendal Regency Izza Alya Ardana Putri; Astin Prima Sari; Ika Dyah Kurniati
MAGNA MEDIKA: Berkala Ilmiah Kedokteran dan Kesehatan Vol 10, No 1 (2023): February
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/magnamed.10.1.2023.60-66

Abstract

Background: Acute Respiratory Infection (ARI) is an acute infection affecting the nose, paranasal sinuses, pharynx, trachea, bronchi, lungs, and epiglottis. ARI is the main cause of mortality and morbidity in toddlers in the world. The incidence of ARI can be prevented by exclusive breastfeeding.Objective: To prove the correlation of exclusive breastfeeding with the incidence of ARI in toddlersMethods: This case-control study conducted on December 2021 at the Ringinarum Health Center Kendal Regency. Sampling was conducted by purposive sampling method and was conducted based on inclusion and exclusion criterias.Results: The total samples obtained in this study were 124 samples. This study showed that the characteristics of toddlers with ARI among others the most frequent age is 24-35 months (30,6%), most of them were male (61,3%) and weren’t exclusively breastfed (69,4%). Futhermore, this study also found that there was a correlation between exclusivity of breastfeeding and the incidence of ARI in toddlers (p<0,05). Toddlers who weren’t exclusively breastfed had 5,5 times greater risk of ARI than those who were exclusively breastfed (OR>1).Conclusion: There is a correlation between exclusive breastfeeding with the incidence of acute respiratory infections in toddlers.
Effectiveness of Bitter melon (Momordica charantia L) Extract on Growth of Trichopyton rubrum: In Vitro Study Vika Pangesty; Ika Dyah Kurniati; Kanti Ratnaningrum
MAGNA MEDIKA: Berkala Ilmiah Kedokteran dan Kesehatan Vol 10, No 1 (2023): February
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/magnamed.10.1.2023.19-26

Abstract

Trichophyton rubrum is type of fungus that most often causes superficial fungal infections. Development of herbal ingredients as antifungal therapy is carried out to find alternative therapies for fungal infections. Bitter melon contains various compounds that have potential to be used as antifungals, including flavonoids and saponins. The aim of this study was to determine the effect of bitter melon extract (Momordica charantia L) on the growth of Trichopyton rubrum. This study used bitter melon extract at concentrations of 5%, 25%, 50%, 75% and 100%. Ketoconazole concentrations of 2% was used as a positive control. Pure cultures of Trichopyton rubrum were diluted using physiological NaCl. Fungal growth was observed microscopically and macroscopically. Results showed that Trichopyton rubrum grew at a concentration of 5% while at concentrations of 25%, 50%, 75% and 100% there was no Trichopyton rubrum growth. Bitter melon extract at a concentration of 25% had similar effect as ketoconazole 2%. Conclusion Bitter melon extract at concentrations of 25%, 50%, 75% and 100% had a similar effect to 2% ketoconazole in inhibiting the growth of Tricophyton rubrum.
Biskuit CERIA (Cangkang Telur Kombinasi Kurma dan Madu) sebagai Snack Alternatif untuk Meningkatkan Status Gizi Anak Hema Dewi Anggraheny; Aisyah Lahdji; Tri Kartika Setyarini; Ika Dyah Kurniati
Jurnal Surya Masyarakat Vol 6, No 1 (2023): November 2023
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/jsm.6.1.2023.20-25

Abstract

Many studies state that most cases of malnourished children, such as stunting, experience a lack of calories and protein. So that one of the focuses is to improve the nutritional status of children, especially by making food preparations from ingredients that are high in calories and protein, and of course those that are of interest to children in terms of taste and shape. Egg shells are an alternative food ingredient that is rich in protein and calcium. In addition, dates and honey produce a natural sweet taste, and have high nutritional value. The purpose of this activity is to provide alternative snacks for children in the form of eggshell cookies, a combination of dates and honey. The method starting with making egg shell cookies a combination of dates and honey (Ceria), and determining the right recipe for these biscuits, in terms of taste and shape. Then tested the nutritional composition (calories, carbohydrates, protein, fat, sugar, and fiber). Furthermore, the cookies were distributed to partners, namely mothers who have children aged 6 months to 9 years and health cadres in the Kedungmundu Village, Semarang. The result for this research was Ceookies “Ceria” with the ingredients of eggshell flour, wheat flour, cornstarch, dates, honey, and egg yolks. The nutritional composition produced in 100 grams of cookies produces 511 kcal calories, 63,7 grams of carbohydrates, 0,83 grams of protein, 28,3 grams of fat, 49,5 grams of fiber, and 7 grams of sugar. Ceria cookies (egg shell combination of dates and honey) can be given as an alternative food supplement for children, with the appropriate nutritional composition and using natural ingredients without artificial sweeteners or preservatives.
Analisis Asupan Protein dan Energi pada Balita Undernutrition di Wilayah Kerja Puskesmas Kedungmundu Anika Intan Nur Aliyah; Ika Dyah Kurniati; Hema Dewi Anggraheny; Oky Rahma Prihandani; Tri Kartika S; Rizky Ika Riani
Prosiding Seminar Nasional Unimus Vol 6 (2023): Membangun Tatanan Sosial di Era Revolusi Industri 4.0 dalam Menunjang Pencapaian Susta
Publisher : Universitas Muhammadiyah Semarang

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Abstract

Latar Belakang:  Undernutrition merupakan keadaan status gizi  dimana jumlah energi yang dikeluarkan lebih banyak daripada energi yang masuk ke dalam tubuh Kekurangan energi protein dikategorikan berdasarkan underweight, stunting dan wasting Hal ini berdampak pada gangguan pertumbuhan fisik hingga kognitif dan kerentanan terhadap infeksi. Tujuan penelitian ini adalah mengetahui apakah terdapat perbedaan asupan energi dan protein pada balita undernutrision di wilayah kerja Puskermas Kedungmundu.   Metode Penelitian : Penelitian deskriptif analitik dengan pendekatan cross sectional. Penelitian ini dilakukan pada bulan Maret 2023, dengan total sampling yaitu sebanyak 24 balita undernutition di wilayahkerja Puskesmas Kedungmundu pada bulan Maret 2023. Instrumen yang digunakan untuk menilai asupan energi dan protein adalah Food Record Food Frequency Questionnaire Semikuantitatif. Data yang diperoleh dianalisis menggunakan uji One Way Anova.  Hasil : Pada balita stunting rata-rata konsumsi energi sebanyak 929.04 kkal per hari sedangkan untuk konsumsi protein sebanyak 46.73 gram per hari. Sedangkan untuk balita underweight, rata-rata konsumsi energi sebesar 883.31 kkal/hari dan kategori protein sebanyak 36.41 gram/hari. Balita yang mengalamistunting-underweight rata rata mengkonsumsi energi sebanyak 946.08 kkal/hari dan protein sebanyak 41.38 gram/hari. Hasil analisis untuk kategori asupan energi didapatkan nilai p-value 0,716, sedangkan kategori asupan protein, didapatkan nilai p-value 0,331 sehingga dapat dikatakan tidak terdapat perbedaan yangsignifikan antara asupan energi maupun asupan protein antara balita yang mengalami stunting, underweight maupun stunting-underweight.  Kesimpulan : Asupan protein dan energi pada balita yang mengalami stunting, underweight maupun stunting-underweight tidak berbeda signifikan, namun asupan energinya dibawah angka kecukupan.   Kata kunci : nutritional status, toddler, energy intake, protein intake
Efek Tingkat Stres Mahasiswi Blok 19 – 20 Terhadap Siklus Menstruasi Yuliana Rochmawati Safitri; Muhamad Irsam; Ika Dyah Kurniati
Prosiding Seminar Nasional Unimus Vol 3 (2020): Optimalisasi Hasil Penelitian dan Pengabdian Masyarakat Menuju Kemandirian di Tengah P
Publisher : Universitas Muhammadiyah Semarang

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Abstract

Gangguan siklus menstruasi sering dijumpai pada remaja  hingga dewasa. Kegiatan akademik dapat menyebabkanstres psikologis. Siklus mentruasi dapat terganggu salah satunya akibat stres psikologis. Tujuan dari penelitian iniadalah membuktikan pengaruh antara tingkat stres blok 19 – 20 terhadap siklus menstruasi pada Mahasiswi FakultasKedokteran Universitas Muhammadiyah Semarang (FK UNIMUS). Rancangan penelitian ini observasional analitikdengan pendekatan cross sectional. Sampel yang digunakan adalah mahasiswi FK UNIMUS blok 19 – 20. Penilaianstres menggunakan keusioner Depression Anxiety Stress Scale (DASS – 42) dan penilaian siklus menstruasi melaluiwawancara. Untuk mengetahui pengaruh antara tingkat stres terhadap siklus menstruasi digunakan uji rank spearman. Tingkat stres terbanyak adalah stres ringan (35,4%) dan siklus menstruasi terbanyak adalah oligomenorea (47,9%).Berdasarkan uji rank spearman antara tingkat stres terhadap siklus menstruasi didapatkan hasil signifikan dengan p=< 0,001 (<0,05) serta koefisien korelasi sedang (0,538). Ada pengaruh yang signifikan antara tingkat stres blok 19 –20 terhadap siklus menstruasi pada mahasiswi FK UNIMUS Kata kunci: Tingkat stres, Siklus menstruasi, mahasiswi kedokteran
The Relationship Of Mother's Knowledge About DPT Aefi To Compliance In Basic Immunization Ulfa Wahyuningsih; Oky Rahma Prihandani; Ika Dyah Kurniati
Saintika Medika Vol. 19 No. 2 (2023): December 2023
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol19.SMUMM2.25724

Abstract

Background : Based on Riskesdas, child immunization data in Pati City in 2018 was Hepatitis B immunization 95.49%, BCG immunization 95.60%, DPT-Hib 1-3 immunization 76.33%, Polio immunization 89.24%, and Measles immunization 90.53%. The aim of this research was to determine the relationship between maternal knowledge about KIPI DPT and compliance with basic DPT immunization in Growong Kidul Village, Juwana District. Methods : This research is a descriptive observational study with a cross sectional approach, sampling was carried out using a random sampling method with inclusion and exclusion criteria, and data analysis used Spearman Rank. Result : In the study, 48 respondents (84.2%) were aged 20-35 years, 20 respondents (35.1%) had high school/vocational education, 40 respondents (70.2%) were housewives, 30 respondents (52.6%) had knowledge sufficient, and 47 respondents (82.5%) had timely DPT immunization for children. In the Spearman Rank test, the values obtained were p=0.001 and r=0.435, which means that there is a relationship between maternal knowledge and compliance with DPT basic immunization with a correlation of sufficient strength. Conclusion : Mother's knowledge is related to compliance with basic DPT immunization in Growong Kidul Village, Juwana District.
Secondary Metabolites Production of Bacillus spp. Isolated from Sea Cucumbers (Holothuria scabra) and their Activity against Mycobacterium smegmatis Maya Dian Rakhmawatie; Aida Zakiyatul Fikriyah; Ika Dyah Kurniati; Nanik Marfu&#039;ati; Stalis Norma Ethica
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 20, No 2 (2023)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.004843

Abstract

New anti-tuberculosis agents are very important due to Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis problems. Mycobacterium smegmatis can be used to replace Mycobacterium tuberculosis as bacteria test to increase the velocity of anti-tuberculosis screening. To answer the need for new drugs, exploration of secondary metabolites from Bacillus spp. can be conducted. Bacillus spp. are known to produce antimicrobials, including discovery of iturins, fengycins, and pumilacidins. This study explored the Bacillus spp. isolated from fermented intestines of Holothuria scabra. The production of Bacillus sp. Holothuria scabra Fermented Intestine (HSFI) secondary metabolites was done using culture media containing starch as a carbon source, as well as yeast and peptone as a nitrogen source. Production capacity of secondary metabolites of Bacillus sp. HSFI was calculated, to determine its potential as an antibacterial producer. Inhibition testing of secondary metabolites of Bacillus sp. HSFI against M. smegmatis was performed using the Kirby-Bauer disk diffusion method. Based on the results of the inhibition test, it was concluded that Bacillus sp. HSFI-9 has the greatest potential to inhibit the growth of M. smegmatis, with a moderate inhibition (7.67 mm). Production of secondary metabolites from Bacillus sp. HSFI-9 is exceptionally good with an extract production capacity of 24.6 mg/L.
Co-Authors Afiana Rohmani Afiana Rohmani Agus Saptanto Aida Zakiyatul Fikriyah Aini, Gita Nurtaningtyas Aini, Hasna Nabiilah Nur Aisyah Lahdji Aisyah Lahdji, Aisyah Ali Rosidi Amygda, Rony Andra Novitasari Andra Novitasari Anika Intan Nur Aliyah Arfiyanti, Mega Pandu Ariwangsya, Ricko Dien Astin Prima Sari Astuti, Yoni Azmi Yunita Dhevana Pradika Yanda Putra Diana Handaria Diaz, Pramayshera Erinda Ayuning Dinda Tiara Firdaus Dyah Dwi Putri Anggraini Dyah Mustika Nugraheni Dyah Mustika Nugraheni Dyah Mustika Nugraheni Dyah Mustika Nugraheni Dyah Mustika Nugraheni Eka Oktaviani Saputri Galuh Ramaningrum, Galuh Ginda Nabila Choirunnisa Harsoyo Notoatmojo Hema Dewi Anggraheny Hema Dewi Anggraheny Henas Deliara Ika Riyani, Risky Islamilenia, Nurul Syifa Izza Alya Ardana Putri Jayawarsa, A.A. Ketut Kanti Ratnaningrum Kanti Ratnaningrum Laila Arina Hukma Adila Martono, Wahyu Budi Maya Dian Rakhmawatie Mega Pandu Arfiyanti Mega Muhamad Irsam Muhammad Ilham Gandi Ilham Muslimah Muslimah Mutiara Aura Kusuma Mutiara Aura Kusuma Nabilah Rochmaningrum, Putri Nanik Marfu&#039;ati Netra Mada Subiyanto Novianti Novianti Nugraheni, Dyah Mustika Nurtika Afi Wijayanti Oky Rahma Prihandani Primasari, Astin Putri, Feby Ananda Rahmatullah, Dyfan Elian Retno Indrastiti Retno Indrastiti Rizky Ika Riani Rizqiawan, Andika Rusyidie, Rijzal Sari, Astin Prima Setyoko . SOFIATUN, KAROMAH RIZKY Stalis Norma Ethica Sufiati Bintanah Swasty Swasty, Swasty Tefia Riswanda Lumban Gaol Tri Kartika S Tri Kartika Setyarini Tri Kartika Setyarini, Tri Kartika Ulfa Wahyuningsih Vika Pangesty Wafi, M Azka Hibbat Wahju Budi Martono Wahju Ratna Martiningsih Yanuarita Tursinawati Yanuarita Tursinawati, Yanuarita Yovita Nur Latifah Yuliana Rochmawati Safitri