Yurika Sastyarina
Laboratorium Penelitian dan Pengembangan Kefarmasian “Farmaka Tropis”, Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

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Isolasi dan Karakterisasi Kitin dari Limbah Cangkang Kerang Asia (Corbicula fluminea): Isolation and Characterization of Chitin from Asian Shell Waste (Corbicula fluminea) Ameilia Rachmadianty; Fika Aryati; Yurika Sastyarina
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (303.867 KB) | DOI: 10.25026/mpc.v14i1.543

Abstract

Chitin compounds are compounds that can be found from various animals of the Crustaceae group, for example such as crabs, shrimp, and shellfish. The purpose of this study was to find out the chitin content and chitin characteristics of asian shell waste (Corbicula fluminea). The stage of chitin insulation includes the process of deproteination using Sodium Hydroxide 3.5%, and the next process is the process of demineralization using Hydrochloric Acid 1 N. From the results of the isolation obtained chitin characterization in the form of chitin yield is 82.75%, with a grayish-white powder texture, and odorless, it perfectly soubled in Hydrochloric Acid 1 N, has a water content of 0.1764% and ash content of 58.0753%.
Pengaruh Waktu Fermentasi Sari Kulit Buah Naga Merah (Hylocereus polyrhizus) Terhadap Total Bakteri Asam Laktat (BAL): Effect of Fermentation Time of Red Dragon Fruit Peel Juice (Hylocereus polyrhizus) on Total Lactic Acid Bacteria (LAB) Aprilia Wulandari; M. Arifuddin; Yurika Sastyarina
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (289.059 KB) | DOI: 10.25026/mpc.v14i1.545

Abstract

Fermentation process decomposes lactose into lactic acid and various other components with success parameters seen from the pH value and Total Lactic Acid Bacteria. The purpose of this research is to analyze the effect of the fermentation time of the Red Dragon Fruit peel extract on the pH value and lactic acid bacteria. The method includes the process of extracting samples and pasteurizing the juice and then proceeding with fermentation with variations of 3, 4, 5, and 6 days at 37ºC. In addition, the extract was prepared into a test solution with graded dilutions for further testing of totaled LAB using the Total Plate Count (TPC) method. The best pH value is showing in the 5-day fermentation time, which is 3.82 and the best LAB value is showing in the 6-day fermentation time, which is 18 x . The results showed that the time of fermentation affected the pH and LAB value.
Pengaruh Waktu Fermentasi Bakteri Asam Laktat Dari Sari Kulit Buah Naga Merah (Hylocereus Polyrhizus) Terhadap Aktivitas Bakteri Propionibacterium acne: Effect of Lactic Acid Bacteria Fermentation Time from Red Dragon Fruit Peel Juice (Hylocereus Polyrhizus) on the Activity of Propionibacterium acne Cindy Puspita Perdana; M. Arifuddin; Yurika Sastyarina
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (278.651 KB) | DOI: 10.25026/mpc.v14i1.548

Abstract

Fermentation of lactic acid bacteria from Red Dragon Fruit peel extract (Hylocereus polyrhizus) produces bacteriocins that can inhibit the growth of pathogenic bacteria. The purpose of this research is to the Red Dragon Fruit peel extract that has been fermented using lactic acid bacteria has the potential to inhibit the growth of Propionibacterium acne bacteria. The method includes the process of extracting samples and pasteurizing the juice and then proceeding with the fermentation process with variations in time of 3 days, 7 days, 12 days, and 14 days at 37?C. Antibacterial testing was carried out using the good method. The results showed that there was an effect of fermentation time on a low pH value of 3.98. As well as antibacterial testing can inhibit the growth of propionibacterium acne bacteria with the largest inhibition zone shown in the 7th day fermented extract at a concentration of 50% at 22.72 mm, a concentration of 75% is 22.99 mm, and a concentration of 100% is 25.97 mm.
Evaluasi Penggunaan Obat Antiemetik pada Penderita Kanker Payudara Pasca Kemoterapi: Evaluation of Antiemetic Drugs Use in Breast Cancer Patients After Chemotherapy Dhea Amanda Sabilla Fauzi; Hajrah Hajrah; Yurika Sastyarina
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (257.823 KB) | DOI: 10.25026/mpc.v14i1.551

Abstract

Data from the Ministry of Health Republic Indonesia in 2018 showed 42,100 women had breast cancer. Chemotherapy is the main choice of treatment for treating cancer, but it has several side effects, such as nausea and vomiting. The aims of this research, to identify characteristics breast cancer patient, classification risk of chemotherapy induce of nausea and vomiting also appropriate use of antiemetic to prevent chemotherapy side effect. Observational research had been use for this study with retrospective data collection based on patient medical records in January-December 2020. The results showed that breast cancer patients were women with age range of 46-55 years with percentage 38.1% and 33.33% had Body Mass Index (BMI) Obesity I. Combination of Antibiotics and Taxanes is the most widely used by 71.45% and has the most common risk classification of moderate nausea and vomiting. The most widely used antiemetic is a combination of 5-Hydroxitryptamine-3, Antagonists Histamine 2, and Dexamethasone. 96.2% compliance with antiemetic use was achieved and 3.8% was not achieved.
Karakteristik Pasien Terkonfirmasi Coronavirus disease (COVID-19) di RS X Samarinda Periode Maret-Desember 2020: The Characteristics of Confirmed Patients Coronavirus disease (COVID-19) at RS X Samarinda in March-December 2020 Ridha Siti Ruhama; Febrina Mahmudah; Yurika Sastyarina
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (285.692 KB) | DOI: 10.25026/mpc.v14i1.582

Abstract

Coronavirus disease (COVID-19) is a virus that has become a world pandemic including Indonesia. East Kalimantan is a province with a total of 71,092 confirmed cases of covid-19 as of March 28, 2020. The RS X Samarinda has 660 confirmed cases covid-19 during march - December period in 2020. This research aims to identify characteristics of patients covid-19 at RS X Samarinda in March - December 2020. This research is descriptive by retrospective methods. Data collection is conducted quantitatively with a sampling technique. Research instruments are 100 data inclusions of patient medical records. The results of this research show that the dominant 51% are male and 49% are female. The most age groups 34% in the early aged (46-55 years old), with further treatments >7 days as much as 65%. Patients who have 31% komorbides and without comorbidity as much as 69% in the category 87.09% diabetes mellitus. Patients data of 58,82% experienced one of the clinical symptoms of coughing/sniffles/throat pain.
Isolasi dan Karakterisasi Kitosan dari Limbah Cangkang Kerang Asia (Corbicula fluminea): Isolation and Characterization of Kitosan from Asian Shell Waste (Corbicula fluminea) Rizki Noor Amelia; Fika Aryati; Yurika Sastyarina
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (277.508 KB) | DOI: 10.25026/mpc.v14i1.583

Abstract

Chitosan is a substance contained in shellfish that is the most biopolymer after cellulose. The study aims to determine the best yield of chitosan results of Asian shell isolation (Corbicula fluminea) based on variations in Sodium hydroxide concentration and length of deacetylation process, and to find the characteristics of chitosan isolation results based on International Standards. The process of chitosan isolation goes through several stages, namely deproteination using a solution of Sodium hydroxide 3,5% at a temperature of 65°C for 2 hours, demineralization using a solution of Hydrochloric acid 1N at a temperature of 65°C for 2 hours, and the stage of deacetylation that is optimized with variations in Sodium hydroxide concentration of 40%, 50%, and 60% and variations in the length of stirring time of 30, 60, and 90 minutes. The results showed the best chitosan yield of 90,1% obtained from the deacetylation process using a Sodium hydroxide concentration of 60% with a stirring time of 60 minutes. The resulting chitosan characteristics are white powder, odorless, soluble in 2% acetic acid, and has a water content of 0%.
Kajian Potensi Interaksi Obat pada Pasien COVID-19 di Rumah Sakit X Kota Samarinda: Study of Potential Drug Interactions in COVID-19 Patients at Hospital X Samarinda City Shofia Siza Maulidia; Febrina Mahmudah; Yurika Sastyarina
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (304.193 KB) | DOI: 10.25026/mpc.v14i1.587

Abstract

Coronavirus disease 2019 (COVID-19) is a respiratory infectious disease caused by a coronavirus known as SARS-CoV-2 and is currently a worldwide pandemic. Treatment management for COVID-19 patients is grouped based on the level of symptoms experienced by the patient. The use of large amounts of drugs (polypharmacy) in COVID-19 patients with moderate and severe symptoms can increase the possibility of drug interactions. This study aims to determine patient characteristics and the potential for drug interactions in COVID-19 patients at Hospital X Samarinda City. The data collection method was conducted retrospectively based on the medical records of COVID-19 patients hospitalized from March to December 2020. Data on potential drug interactions were analyzed using the Drugs.com application. The results showed that of the 30 patients with COVID-19, male-dominated (60%) and aged between 46 and 55 years (50%). Data on potential drug interactions showed that 28 out of 30 patients had the potential to experience drug interactions in the categories of severe (9,23%), moderate (74,62%), and mild (16,15%).
Kajian Literatur: Aktivitas Antioksidan Ekstrak Tanaman Cempedak (Artocarpus champeden Spreng): Literature Review: Antioxidant Activity of Cempedak Plant Extract (Artocarpus champeden Spreng) Aulia Alfath Rahmawati; Mirhansyah Ardana; Yurika Sastyarina
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (237.211 KB) | DOI: 10.25026/mpc.v14i1.594

Abstract

Antioxidants are compounds that can counteract free radicals. One of the plants that have antioxidant activity is cempedak, because cempedak contains flavonoids compounds. This writing aims to determine the antioxidant activity of cempedak plants based on a review of several literatures. The method of writing a literature review uses a journal search from Google Scholar. Based on the literature review that has been carried out, the leaves and bark of cempedak have antioxidant activity. Based on the literature review of antioxidant activity of cempedak, methanol extract of stem bark had antioxidant activity of 100,26 ppm, leaf methanol extract 8,88 ppm, leaf ethanol extract 52,7706 ppm, leaf ethyl acetate fraction 4,282 ppm. The part of the cempedak plant that has the highest antioxidant activity is found in the leaves with the ethyl acetate fraction which shows an IC50 value of 4,282 ppm. Based on the IC50 value obtained, the ethyl acetate fraction of cempedak leaves has a very strong antioxidant activity because the IC50 is below 50 ppm.
Aktivitas Antioksidan Teh Herbal Daun Kelor (Moringa oleifera) dan Teh Herbal Bawang Dayak (Eleutherine americana): Antioxidant Activity Herbal Tea of Kelor (Moringa oleifera) and Herbal Tea Bawang Dayak (Eleutherine americana) Amalia Srikurniawati; Sabaniah Indjar Gama; Yurika Sastyarina
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 15 (2022): Proceeding of Mulawarman Pharmaceuticals Conferences (Proc. Mul. Pharm. Conf.)
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/mpc.v15i1.610

Abstract

Analisis Kandungan Zat Gizi Makro Cookies Kombinasi Tepung Daun Kelor (Moringa oleifera L.) dan Tepung Ubi Jalar Ungu (Ipomea batatas L.): Analysis of Macro Nutrient Content of Cookies Combination of Moringa Leaf Flour (Moringa oleifera L.) and Purple Sweet Potato Flour (Ipomea batatas L.) Fitriani Miranda; Andi Tenri Kawareng; Yurika Sastyarina
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 15 (2022): Proceeding of Mulawarman Pharmaceuticals Conferences (Proc. Mul. Pharm. Conf.)
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/mpc.v15i1.620

Abstract

Co-Authors Abdul Mutalib Adinda Niti Meilaningrum Aditya Fridayanti Amalia Srikurniawati Ameilia Rachmadianty Andi Tenri Kawareng Angga Cipta Narsa Aprilia Wulandari Arsyik Ibrahim Asri Wido Mukti Asti Rahayu Asti Rahayu Aulia Alfath Rahmawati Ayida Mawarda Cindy Puspita Perdana Cyntia Bella Anggraini Dewi Mayasari Dewi Perwito Sari Dewi Rahmawati Dhea Amanda Sabilla Fauzi Enggar Wijayanti Erwin Samsul Febrina Mahmudah Fidhia Rara Lande Fika Aryati Fika Aryati Fitriani Miranda Ganjar Firmansyah Hadi Kuncoro Hajrah Hajrah Hajrah Hajrah Hajrah Hajrah Hajrah Hajrah Hanny Chynthia Vehrawati Hardani, Prisma Trida Herman Herman Hidayatunnikmah, Nina Intan Ayu Kusuma Pramushinta Irmayanti Irwan Islamudin Ahmad Istnaini Reiza Fatimah Jaka Fadraersada Junaidi Khotib Khusnul Khatimah Rukhayyah Lisna Meylina M. Arifuddin M. Khalid Akbar Mahfuzun Bone Martalena Ramli Maulidya Maulidya Miranda Aurora Pratiwi Mirhansyah Ardana Mirhansyah Ardana Muhamad Handoyo Sahumena Muhamad Handoyo Sahumena Muhammad Faisal Muhammad Yusuf Mutiara Citra Refordayanti Nanda Uswatun Hasanah Novita Eka Kartab Putri Novita Eka Kartab Putri Nur Amiiroh Isyraqi Nur Aprilianti Nur Mita Nurul Fitriani Purbosari, Ira R. Ukun M.S. Soedjanaatmadja Rahmadani, Agung Ridha Siti Ruhama Rifaldy Rahmadillah Riska Novianti Rizal Adi Saputra Rizki Noor Amelia Sari, Dewi Perwito Shofia Siza Maulidia Sri Lestari Sukardiman Tanti Dwi Gunawati Tri Woro Widyanti Triani Yastuti Kuling Wa Ode Rungaya Ningsih Komala Wahyu Trimadianti Wahyu Widayat Yoni Miftahun Nafsiyah Agustin Yuspian Nur Yustika Rahayu Zuhrotun Nafisah