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All Journal JCRS (Journal of Community Research and Service) Jurnal Mandala Pharmacon Indonesia Proceeding of Mulawarman Pharmaceuticals Conferences Jurnal Pengabdian dan Pengembangan Masyarakat Indonesia SWARNA: Jurnal Pengabdian Kepada Masyarakat Journal of Pharmaceuticals and Natural Sciences Journal of Tropical Pharmacy and Chemistry Jurnal Sains dan Kesehatan Jurnal Riseta Naturafarm
Almeida, Maria
Fakultas Farmasi, Universitas Mulawarman, Indonesia
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences

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Effectivity of Antihypertensive Drugs Use in Pregnant Woman with Diagnoses of Preeclampsia Hospitalized at Abdoel Wahab Sjahranie Hospital and Inche Abdoel Moeis Hospital Samarinda City: Efektivitas Penggunaan Obat Antihipertensi Pada Ibu Hamil dengan Diagnosa Preeklampsia Rawat Inap di RSUD Abdoel Wahab Sjahranie dan RSUD Inche Abdoel Moeis Kota Samarinda Difta, Rismania Shita; Mus, Nurul Muhlisa; Almeida, Maria; Herman, Herman
Jurnal Riseta Naturafarm Vol. 2 No. 2 (2025): Jurnal Riseta Naturafarm
Publisher : B-Creta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/jrn.v2i2.7384

Abstract

The use of appropriate and effective antihypertensive drugs is needed so that blood pressure in preeclampsia patients can be controlled so as not to endanger the condition of the mother and fe-tus. This study aims to determine the rationality and effectiveness of the use of antihypertensive drugs at RSUD Abdoel Wahab Sjahranie and RSUD Inche Abdoel Moeis in the period January 2022 - December 2023 which was carried out through retrospective data observation of hospital-ized patients with a total of 12 samples (RSUD Abdoel Wahab Sjahranie) and 10 samples (RSUD Inche Abdoel Moeis). The results of the evaluation of the rationality of antihypertensive drugs used were assessed as appropriate patients, appropriate indications, appropriate drugs, ap-propriate doses and appropriate time intervals of administration each by 100% based on the 2016 POGI guideline, Hospital Formulary, 2023 SOMANZ guideline, 2021 ISSHP guideline, and 2019 ACOG guideline. The effectiveness of using Methyldopa monotherapy showed better blood pressure reduction results (34.81/12.37 mmHg) than Nifedipine (21.41/5.6 mmHg), while the combination of Nifedipine and Methyldopa showed greater results than monotherapy (38.5/15.2 mmHg).
Formulation of Air Freshener Gel Combination of Mint Leaf Essential Oil (Mentha piperita L.) and Lemon (Citrus limon (L) Burm F.) Hafidzah, Nurul; Putri, Novita Eka Kartab; Almeida, Maria; Rusman, Arman; Herman, Herman
Journal of Pharmaceuticals and Natural Sciences Vol. 1 No. 2 (2024): J. Pharm. Nat. Sci.
Publisher : B-CRETA Publisher (CV. Borneo Citra Kreatama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/qds89550

Abstract

Air freshener gel is a semi-solid fragrance product that uses carrageenan and pectin as gel-forming components to overcome unpleasant odors when in a room with high temperatures. The purpose of this study was to determine the composition of carrageenan and pectin as gel-forming materials for air fresheners and the composition of the aroma comparison of mint oil (Mentha piperita L.) and lemon (Citrus limon (L) Burm F). The gel base was made with a ratio of carrageenan: pectin concentration of 1: 2; 1.8: 1.2; 2.5: 0.5 then the base was evaluated including organoleptic examination, stability test and gel hardness. The best base was then added with mint oil and lemon with a ratio of 1: 1.5; 1.25: 1.25; 1.5: 1 and the gel preparation was evaluated with organoleptic parameters, gel stability, gel hardness, liquid evaporation, fragrance resistance and hedonic test. The results of the study showed that the best base preparation after the evaluation of the base was a ratio of carrageenan: pectin concentration of 25: 0.5. Evaluation of the preparation with the addition of mint leaf oil (Mentha piperita L.) and lemon (Citrus limon (L) Burm F) to the base showed a value that was not too significant in the evaluation results. In the hedonic test, the formula with the addition of 2.5%: 2.5% mint leaf oil (Mentha piperita L.) and lemon (Citrus limon (L) Burm F) was the formula preferred by the panelists. So it can be concluded that the carrageenan and pectin combination room freshener gel with a concentration ratio of 2.5: 0.5% can be formulated as a base for room freshener gel preparations, namely producing a chewy and elastic gel base. The formulation of the most preferred combination of mint leaf essential oil and lemon oil as a gel fragrance is with a concentration of 2.5: 2.5%, because it produces a refreshing aroma
Activity Test of The Combination Papaya Leaf Extract (Carica papaya L.) and Soursop Leaf Extract (Annona muricata L.) on Decreasing Blood Glucose Levels in Rats (Rattus norvegicus) Arfiani, Putri Yuni; Almeida, Maria; Arifian, Hanggara; Arief, Maryam Jamila; Herman, Herman
Journal of Pharmaceuticals and Natural Sciences Vol. 1 No. 3 (2024): J. Pharm. Nat. Sci.
Publisher : B-CRETA Publisher (CV. Borneo Citra Kreatama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/jpns.v1i3.101117

Abstract

Diabetes mellitus (DM) is one of the most common health disorders and its prevalence rate is increasing every year. Natural compounds can be an alternative treatment for DM. Previous re-search reports for papaya leaves (Carica papaya L.) and soursop leaves (Annona muricata L.) showed activity in lowering blood glucose levels when used alone. Therefore, in this study, the two samples were combined to lower blood glucose levels. Both leaves were extracted using the decoction method. This study aims to identify secondary metabolite compounds in papaya leaf extract (Carica papaya L.) and soursop leaf extract (Annona muricata L.), then continued with determining the activity and effectiveness of lowering blood glucose levels. The results of the identification of secondary metabolite compounds showed several groups of compounds such as flavonoids, saponins and tannins. The combination of papaya leaf extract and soursop leaf extract showed a decrease in blood glucose levels. In more detail, EDPS 1:2 and EDPS 2:1 were statistically significant against negative controls. EDPS 1:2 showed the most effective percentage reduction in blood glucose levels at 22.72%  
Co-Authors Adam M. Ramadhan Agus Setiawaty Angga Cipta Narsa Arfiani, Putri Yuni Arief, Maryam Jamila Arifian, Hanggara Arifuddin, M Baso Didik Hikmawan Bone, Mahfuzun Brilian Dwisaputra Bandu Daniel Happy Putra Devara, Rachel Difta, Rismania Shita Dyah Ayu Puspo Rini Elit Dita Paradila Fajar Prasetya Farah, Harra Ismi Febrina, Lizma FENNY MARTHA DWIVANY Fenny Martha Dwivany FITRIANI, VICTORIA YULITA Hadi Kuncoro Haeruddin Haeruddin Hafidzah, Nurul Haniko, Natashya Angelica Helmi Helmi Helmi Helmi Helmi Helmi Herman Herman Hikmawan, Baso Didik Ibrahim, Arsyik Islamudin Ahmad Iswahyudi Iswahyudi Iswahyudi Iswahyudi ISWAHYUDI ISWAHYUDI Junaidin, Junaidin Laode Rijai Laode Rijai Laode Rijai M. Arifuddin, M. Maharani, Dhea Nur Fadillah Maryam Jamila Arief Maryam Jamila Arief Muhammad Faisal Muhammad Faisal Muhammad Faisal Mus, Nurul Muhlisa Niken Indriyanti Nur Aini Nur Aini Buring Incau Nur Zakiyah Darajat Nur Zakiyah Darajat Putri, Novita Eka Kartab Rahmadani, Agung Rahmayunitha Muriana Ridhotulloh, Yusuf Isro Rija’i, Hifdzur Rashif RIKI RIKI, RIKI Rizkita Rachmi Esyanti Rusli, Rolan Rusman, Arman Samsul, Erwin Sinthary, Venna Sri Agung Fitri Kusuma Sriwidodo Sriwidodo Supriatno Supriatno Salam Syamsiar, Syamsiar Vina Maulidya Vina Maulidya Yiska Priscilla Septilita Zamruddin, Nur Masyithah