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All Journal Jurnal Kesehatan Andalas Jurnal Riset Kimia Jurnal Penelitian Kesehatan Suara Forikes Majalah Kedokteran Andalas Jurnal Biomedika dan Kesehatan Poltekita: Jurnal Pengabdian Masyarakat Archives Pharmacia Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Ilmiah Farmasi Attamru (JIFA) Jurnal Ilmu Kesehatan Indonesia (JIKSI) Jurnal Sosial dan Sains Innovative: Journal Of Social Science Research The International Science of Health Journal Jurnal Kesehatan Masyarakat Indonesia (JKMI) Jurnal Riset Ilmiah Jurnal Penelitian dan Pengkajian Ilmiah Jurnal Sains, Teknologi dan Kesehatan Poltekita: Jurnal Pengabdian Masyarakat
Miftah Irramah
Universitas Andalas
Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Original Research The Effect of Yoga or Nonpharmacotherapy on Dysmenorrhore in Medical Students of Andalas University, Indonesia Wardah Astarini, Rifqah; Syahrul, Muhammad Zulfadli; Nour, Mustafa; Indra, Beni; Aladin, Aladin; Irramah, Miftah
Jurnal sosial dan sains Vol. 4 No. 9 (2024): Jurnal Sosial dan Sains
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/jurnalsosains.v4i9.1522

Abstract

Background: Dysmenorrhea is a menstrual pain that is often experienced by young women, with a global prevalence of 16.8-81%. In Indonesia, the prevalence reaches 54.89%, with adolescent girls being the largest group. Treatment generally uses analgesics, but it has side effects. Yoga as a non-pharmacological therapy can reduce pain through muscle relaxation. Purpose: Analyzing the effect of yoga therapy on the intensity of the degree of dysmenorrhea in female students of the Class of 2018 Undergraduate Medical Education Study Program, Faculty of Medicine, Andalas University. Methods: This research uses a pure experimental design with a pre-test, post-test, and only group design, with a sample size of 32 people. The research instrument used in the study was a pre-test and post-test questionnaire, which contained VAS scores and guidelines regarding yoga movements. The questionnaire contains a Visual Analog Scale (VAS), which consists of a vertical scale from 0 to 10 cm. Results:  The results showed there were no differences related to age. As many as 18% of respondents usually took analgesics, while 81.3% did not take analgesics to treat dysmenorrhea before yoga therapy. Meanwhile, after yoga therapy, 5 out of 6 respondents who usually consumed analgesics in previous menstrual cycles no longer consumed analgesics, and one respondent still consumed analgesics. Bivariate analysis showed a value of p=0.00 (p<0.05), which means there is a relationship between the provision of yoga therapy and the degree of dysmenorrhea. Where providing yoga therapy can reduce the intensity of pain in respondents who experience dysmenorrhea. Conclusion: This research concludes that there is a significant relationship between the provision of yoga therapy and the degree of dysmenorrhea.
HUBUNGAN AKTIVITAS FISIK DENGAN KADAR ASAM URAT DARAH PADA ORANG LANJUT USIA DI PUSKESMAS PADANG KANDIS KABUPATEN LIMA PULUH KOTA Salsabilla, Ainna Fajra; Irramah, Miftah; Lestari, Yuniar
EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan Vol. 2 No. 4 (2025): EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan, Desember 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/empiris.v2i4.1964

Abstract

Uric acid is a crystalline acid, the end product of purine metabolism. Normal uric acid levels depend on age and gender, exceeding the normal limit indicates an increase in uric acid levels. One contributing factor to elevated uric acid is increased physical activity. This study aims to determine the Relationship between Physical Activity and Uric Acid Levels in elderly people at the Padang Kandis Health Center, Lima Puluh Kota Regency. This observational analytic study, with a cross sectional research design and includes 30 elderly participants meeting inclusion and exclusion criteria, assessed through the Global Physical Activity Questionare (GPAQ). Uric acid levels were measured using Autocheck digital instruments and test strips. Data analysis utilized the Chi-Square Test. Results revealed an equal ratio of normal and high uric acid levels in the elderly (50%), and the highest level of physical activity was light physical activity (46,6%). High uric acid levels were found more in the elderly with low physical activity levels (46,3%). The Chi-Square Test yielded  p=0,208 (>0,05).This study found no significant relationship between physical activity and uric acid levels in elderly people at the Padang Kandis Health Center, Lima Puluh Kota Regency.
Korelasi Skor SOFA dengan Kadar Kortisol Darah pada Pasien Sepsis di RSUP Dr. M. Djamil Padang Fahmi, Rahmadina Zesfira; Fadrian, Fadrian; Rikarni, Rikarni; Husni, Husni; Bilmahdi, Rohayat; Irramah, Miftah
Jurnal Kesehatan Andalas Vol. 14 No. 3 (2025): November 2025
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v14i3.2671

Abstract

Sepsis is a life-threatening organ dysfunction due to dysregulation of the body's immune response to infection. The Sequential Organ Failure Assessment score (SOFA score) is a diagnostic tool used to quantitatively and objectively assess the level of organ dysfunction. Sepsis as a stressor of systemic inflammation, causes an increase in cortisol secretion by the adrenals to target tissues, which suppresses inflammation. Objective: To determine the correlation between SOFA score and blood cortisol levels in sepsis patients at RSUP Dr. M. Djamil Padang. Method: Observational analytic study with a cross-sectional method. The sample consisted of 55 patients who had been diagnosed with sepsis. The data used was secondary data from medical records. The data were tested using the Spearman correlation test. Result: A correlation was found between the SOFA score and blood cortisol levels, yielding a correlation coefficient of r = 0.338 and a p-value of 0.012. Conclusion: There is a significant moderate correlation between SOFA scores and blood cortisol levels. Keywords:  blood cortisol, sepsis, SOFA score
Hubungan Kadar Cancer Antigen 125 dan Metastasis pada Kanker Ovarium Tipe Epitel Wulandari, Natasya; Rikarni; Irramah, Miftah; Yaswir, Rismawati; Afriani, Nita
Jurnal Ilmu Kesehatan Indonesia Vol. 7 No. 1 (2026): Maret 2026
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v7i1.1332

Abstract

Latar belakang: Kanker ovarium tipe epitel merupakan salah satu jenis dari kanker ovarium, dan merupakan tipe terbanyak (95%). Kanker ovarium menempati peringkat tujuh berdasarkan insiden dan mortalitas di dunia. Salah satu pemeriksaan preoperatif yang dapat dilakukan untuk kanker ovarium adalah pemeriksaan penanda tumor cancer antigen 125 (CA-125). Penelitian memperlihatkan bahwa kadar CA-125 yang tinggi berhubungan dengan metastasis kanker ovarium. Tujuan: Penelitian ini bertujuan untuk mengetahui hubungan kadar CA-125 dan metastasis pada kanker ovarium tipe epitel. Metode: Penelitian ini merupakan penelitian analitik observasional dengan desain cross sectional retrospektif dengan dengan teknik pengambilan sampel consecutive sampling. Sampel adalah pasien kanker ovarium tipe epitel yang bermetastasis sejumlah 15 orang dan tidak bermetastasis sejumlah 15 orang. Hasil: Usia pasien kanker ovarium tipe epitel terbanyak ditemukan pada kelompok usia 41-50 tahun yaitu 30%. Subtipe terbanyak adalah high grade serous yaitu 53,3%.  Sebanyak 73,3% pasien memiliki kadar CA-125  ≥35 U/mL. Organ yang paling banyak mengalami metastasis adalah omentum yaitu 80%. Median kadar CA-125 pada kanker ovarium yang tidak bermetastasis lebih rendah (23,15 U/mL) dibanding yang bermetastasis (>600 U/mL). Hasil uji Chi-square menunjukkan hubungan yang signifikan antara kadar CA-125 dengan metastasis pada kanker ovarium tipe epitel (p=0,001). Kurva ROC menunjukkan nilai cut-off untuk metastasis adalah 139,59 U/mL dengan sensitivitas 93% dan spesifisitas 80%. Kesimpulan: Terdapat hubungan signifikan antara kadar CA-125 dengan metastasis pada kanker ovarium tipe epitel di RSUP Dr. M. Djamil Padang.
HUBUNGAN KADAR UREUM DAN KREATININ SERUM DENGAN FUNGSI KOGNITIF PENDERITA PENYAKIT GINJAL KRONIK Adzra Fadhila Iswan; Restu Susanti; Dian Pertiwi; Lydia Susanti; Almurdi Almurdi; Miftah Irramah
EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan Vol. 3 No. 2 (2026): EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan, Juni 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/empiris.v3i2.2596

Abstract

Chronic Kidney Disease (CKD) may lead to various complications, including cognitive impairment. The causative factor is the toxic substances accumulation in the body, including serum ureum and creatinine. This study aimed to determine the relationship between serum ureum and creatinine levels with cognitive function in CKD patients. Samples were taken using a consecutive sampling technique on 46 CKD patients who were hemodialyzed at RSUP Dr. M. Djamil Padang. Cognitive function was assessed using the Montreal Cognitive Assessment Indonesian version (MoCA-Ina). Serum ureum and creatinine were measured with a spectrophotometer. Data were analyzed using the Chi-Square test. Results showed that CKD patients with cognitive impairment were more likely to be older than 50 years old (54.2%) and male (58.3%), had at least a high school education and above (70.8%), were accompanied by hypertension (75%), and without diabetes mellitus (91.7%). The median serum ureum and creatinine levels in patients with cognitive impairment were 124 mg/dL and 10.05 mg/dL. The relationship between serum ureum and creatinine levels with cognitive function had a 0.039 and 0.768 p-value. There is no relationship between the characteristics of the sample, including age, gender, education level, hypertension, and diabetes mellitus with cognitive function in CKD patients. There is a significant relationship between serum ureum levels and cognitive function, but a non-significant relationship between serum creatinine with the cognitive function of CKD patients.
The Difference in Endothelial Nitric Oxide Synthase Levels in STEMI Patients With Comorbid Diabetes Mellitus And Those Without Comorbid Diabetes Mellitus at RSUP. Dr. M. Djamil Padang Muhammad Bhagus Andina Putra; Eka Fithra Elfi; Rauza Sukma Rita; Mefri Yanni; Miftah Irramah
CENDEKIA : Jurnal Penelitian dan Pengkajian Ilmiah Vol. 3 No. 6 (2026): CENDEKIA : Jurnal Penelitian Dan Pengkajian Ilmiah, Juni 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/cendekia.v3i6.2695

Abstract

Background: Cardiovascular disease is a leading cause of global mortality, with Indonesia ranking third in the highest cardiovascular deaths. Acute myocardial infarction, divided into STEMI and NSTEMI, is part of the acute coronary syndrome due to total occlusion of coronary arteries requiring immediate revascularization. Diabetes Mellitus reduces endothelial nitric oxide synthase (eNOS) and nitric oxide (NO) production, leading to endothelial dysfunction and an increased risk of vascular disease. DM-related endothelial dysfunction affects vascular relaxation and the formation of atherosclerotic plaques as well as thrombi in ST-elevation myocardial infarction (STEMI). Methods: This research was an analytical observational study with a cross-sectional approach, using normality tests and the Mann-Whitney U Test. The research sample was collected using consecutive sampling techniques and obtained from the medical records of 72 confirmed STEMI patients, with and without comorbid Diabetes Mellitus. Results: The research results indicated that the majority of patients were in the age range of 60-69 years (52.7%), male (86.1%), with a Body Mass Index (BMI) of 23-24.9 (45.8%), comorbid hypertension (52.7%), and a history of smoking (72.3%). The mean eNOS level in the control group was Median eNOS 38,839 U/mL with maximum level 584,762 U/ml and minimum 17,024 U/ml. Median eNOS level in the test group was 36,077 U/mL with the maximum level 679,754 U/ml and minimum 1,836 U/ml. Conclusions: There was no significant difference in eNOS levels between the two groups (Sig (2-Tailed) > 0.05).
Pengaruh Pemberian Ekstrak Buah Pohon Andalas (Morus Macroura Miq.) terhadap Gambaran Histopatologi Miokardium pada Tikus Model Aterosklerosis Intan Putri Syamtoni; Henny Mulyani; Rita Hamdani; Noza Hilbertina; Miftah Irramah; Endrinaldi Endrinaldi
CENDEKIA : Jurnal Penelitian dan Pengkajian Ilmiah Vol. 3 No. 6 (2026): CENDEKIA : Jurnal Penelitian Dan Pengkajian Ilmiah, Juni 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/cendekia.v3i6.2698

Abstract

Atherosclerosis is an inflammation that occurs in blood vessels, especially arteries, it could be developed by an accumulation of lipids in the body, which is atherosclerosis causes this to become a major factor of cardiovascular disease. The fruit of the andalas contains flavonoid, morasin C and M for anti-inflammatory. The purpose of this experimental is to see the effect of extract andalas fruits to histologial changes in myocardium of rats with aterosclerosis model. This research was an experimental study with a randomized post test only control group design with using 29 mice which have been divided into 5 groups, there is negative control group (K-), positive control group (K+), treatment group 1 (P1), treatment group 2 ( P2), and treatment group 3 (P3). The results measurement of the weight rat's heart after analysis used the One Way ANOVA test were p = 0.000, that’s mean there was a significant difference of weight rat's heart in each other groups. Measuring the thickness of myocardial cell size used the One Way Anova test, the resulted is p = 0.632, that’s mean there was no relationship between the groups. Measuring the blood vessel thickness were used by One Way ANOVA analysis, the resulted is p = 0.301, that’s mean there was no significant difference in arterial blood vessel thickness in all groups. The conclusion of this study is there was changes in rat heart weight in all groups, there was no significant change in the histopathological size of the myocardium in all groups, lipofuscin was found in 1 sample, necrosis wasn’t found, sicatric tissue wasn’t found, and there was no significant change in the histopathological picture of arterial thickness in this experience.
KARAKTERISTIK PEROKOK DI KALANGAN CIVITAS AKADEMIKA FAKULTAS HUKUM UNIVERSITAS ANDALAS Muhammad Raihan; Fenty Anggrainy; Yuniar Lestari; Miftah Irramah; Yessy Susanty Sabri; Zurayya Fadila
EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan Vol. 3 No. 2 (2026): EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan, Juni 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/empiris.v3i2.1957

Abstract

The number of smokers increases every year. It becomes the focus of the Indonesian government’s attention. Through the healthy campus program, the Indonesian Ministry of Health designated Andalas University as one of the pilot campuses, but there are still smokers on campus. Itsn’t just students who smoke, but lecturers and education staff as well. To determine the characteristics of smokers among the academic civility in Faculty of Law, Andalas University. The method used is descriptive observational with quota sampling technique. The sample consisted of 323 students, 18 lecturers, and 5 staff. Data were collected by questionnaire and analyzed with computerized program. The research results showed that 28.9% of the academic civility at Faculty of Law, Andalas University were smokers. The typical average age is 22 years, dominated by men, in general they also have families who smoke. The highest age for starting smoking is 16 years or older. Smokers are dominated by light smokers. The most commonly consumed type of cigarettes is white cigarettes, but 9.5% also use e-cigarettes. The driving force behind smoking behavior usually the social environment. The level of knowledge of academic civility is sufficient category. The conclusion obtained is that there are still smokers among the academic community, so preventive efforts should be made to reduce the number of smokers on campus.
Co-Authors Adrial Adrial, Adrial Adzra Fadhila Iswan Afriani, Nita Afriwardi Afriwardi Aisyah Elliyanti Aladin Aladin ALADIN ALADIN Almurdi Almurdi Arni Amir Asterina, Asterina Aswiyanti Asri Beni Indra, Beni Bilmahdi, Rohayat Cesar, Afifah Raudhati Dian Pertiwi Eka Fithra Elfi, Eka Fithra Elmatris Sy Endrinaldi Ermayanti, Sabrina Fadrian, Fadrian Fahmi, Rahmadina Zesfira Fathur Rahman Fenty Anggrainy Fereshti Lailani Fika Tri Anggraini Gusti Revilla Hanna Cakrawati Hanum, Fathiya Juwita Harun Harnavi Henny Mulyani Herizal, Hendra Husna Yetti Husni Husni Husnil Kadri Ida Rahmah Burhan Ilhami, Yose Ramda Intan Putri Syamtoni Irena Fathin Amelia Lili Irawati Linosefa Linosefa Lydia Susanti, Lydia Mahata, Liganda Endo Maria Lousiana Muhammad Bhagus Andina Putra Muhammad Raihan Mustafa Nour Nadhira Isza Qushoyyi Nour, Mustafa Novita Ariani Noza Hilbertina Octavia, Fatharani Nabila Putri, Biomechy Oktomalio Rahmani Welan Rahmatini . Rauza Sukma Rita Rayhansyah, Vito Restu Susanti Rifqah Wardah Astarini Rikarni Rikarni Rikarni Rismawati Yaswir Rita Hamdani Rita Hamdani S Setiyowati Salsabilla, Ainna Fajra Selfi Renita Rusjdi Swandi, Khairfani Syahrul, Muhammad Zulfadli Syamsiar, Ana Rianti Syawqi, Rahmat Tafdil, Zhafirah Khairunnisa Tofrizal Tyas Putri Utami Ulya Uti Fasrini VY Susilo Wardah Astarini, Rifqah Wulandari, Natasya Yanni, Mefri Yessy Susanty Sabri Yulia Kurniawati Yuniar Lestari Yustini Alioes Zawata Afnan Zehan Afifa Yusran Zurayya Fadila