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All Journal Indonesian Journal of Conservation JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Jurnal Kimia Riset Jurnal Fitofarmaka Indonesia Journal of Economic, Bussines and Accounting (COSTING) PENDIPA Journal of Science Education CARADDE: Jurnal Pengabdian Kepada Masyarakat Jurnal Ilmu Kefarmasian Indonesia Jurnal Jamu Indonesia Jurnal Mandala Pharmacon Indonesia Pharmacoscript Jurnal Farmamedika (Pharmamedica Journal) SULUH: Jurnal Abdimas Management Studies and Entrepreneurship Journal (MSEJ) Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang Jurnal PORKES Indonesia Natural Research Pharmaceutical Journal (INRPJ) Lumbung Farmasi : Jurnal Ilmu Kefarmasian Medfarm: Jurnal Farmasi dan Kesehatan Mitra Mahajana: Jurnal Pengabdian Masyarakat PROFICIO: Jurnal Pengabdian Masyarakat Pharmaceutical And Biomedical Sciences Journal (PBSJ) Capacitarea : Jurnal Pengabdian Kepada Masyarakat Abdi Implementasi Pancasila: Jurnal Pengabdian kepada Masyarakat Ranah Research : Journal of Multidisciplinary Research and Development Jurnal Ilmiah Multidisiplin Indonesia Jurnal Ilmiah Farmasi Simplisia Jurnal Kesehatan Bakti Tunas Husada Aisyah Journal Of Physical Education International Journal of Contemporary Sciences (IJCS) Journal of Natural Product for Degenerative Diseases Indonesian Journal of Jamu
Andri Prasetiyo
Fakultas Farmasi Universitas Pancasila
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Transportation Other

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Anchoring Analysis and Simulation of Molecular Dynamics of Dayak Onion Plant Compounds (Eleutherine bulbosa (Mill.) URB.) As an Antibacterial Candidate for Methicillin Resistant Staphylococcus aureus Pratamaa, Yuga; Rina Herowati; Nuraini Harmastuti; Andri Prasetiyo
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 3 (2024): January 2024
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v2i1.8334

Abstract

MRSA infection that is growing and limited treatment is evidence that the handling and treatment of the disease is still inadequate so that appropriate drugs are needed as antibacterial against MRSA, the development of natural products, one of which is the dayak onion plant (Eleutherine bulbosa) which has the potential as antibacterial can be done with computational methods, one of which is molecular tethering, molecular dynamics and ADMET prediction. This study aims to predict the ability of natural compounds from dayak onions as antibacterial MRSA. Tethering and molecular dynamics are performed using AutoDock 4.2 and Yasara Dynamic software. The results showed that compounds with the greatest antibacterial potential were eleucanainones with binding energy of -11.91kcal / mol. The results of molecular tethering are then continued with molecular dynamics simulations. The results of molecular dynamics simulations show that the compound has a Root Mean Square Deviation (RMSD) value that is close to the native ligand. Conclusion: Dayak onion compounds (Eleutherine bulbosa) have potential as antibacterial MRSA
Analysis of Molecular Docking and Dynamics Simulation of Mahogany (Swietenia macrophylla King) Compounds Against the PLpro Enzyme SARS-COV-2 Lalu Sanik Wahyu Fadil Amrulloh; Nuraini Harmastuti; Andri Prasetiyo; Rina Herowati
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 10 No. 3 (2023): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v10i32023.347-359

Abstract

Background: Using natural ingredients as antivirals can be considered a treatment for SARS-CoV-2. One of the potential plants, mahogany (Swietenia macrophylla King), is widely used in various countries as an antiviral treatment. Paparin-like protease (PLpro) is an essential cysteine "‹"‹protease that regulates viral replication and interferes with the regulation of immune sensing. Objective: This study aims to predict which compounds in the mahogany plant have good affinity, patterns, and stability interaction against the target protein of SARS-CoV-2. Methods: The drug-likeness parameter using SwissADME was used to screen compounds that will be docked against PLpro using the Autodock program. The parameters observed in molecular docking analysis are the value of bond energy and interaction model to amino acid residues. The compounds in mahogany plants that have the best interactions were then analyzed using molecular dynamics simulation methods to determine the stability of their bonds based on the values of Root Mean Square Deviation (RMSD) and Root Mean Square Fluctuation (RMSF). Results: Twenty-two compounds met the drug-likeness requirements. Molecular docking analysis showed that the compounds predicted to have the best binding affinity and have an interaction pattern similar to natural ligands towards the molecular target of PLpro are 7-deacetoxy-7-oxogedunin and 3β-hydroxy-stigmast-5-en-7-one. The molecular dynamics simulation results revealed that based on the RMSD and RMSF values, the compound 3β-hydroxy-stigmast-5-en-7-one showed higher stability than 7-deacetoxy-7-oxogedunin. Conclusion: 3β-hydroxy-stigmast-5-en-7-one and 7-deacetoxy-7-oxogedunin were predicted to have good interaction with PLPro; however, 3β-hydroxy-stigmast-5-en-7-one showed the higher interaction stability.
SOSIALISASI OLAHRAGA TRADISIONAL DALAM RANGKA PEMAJUAN KEBUDAYAAN INDONESIA Rachman, Fadlu; Armanjaya, Satria; Fajar Ramadhan, Ziko; Prasetiyo, Andri; Sari, Felinda; Nuruhidin, Ahmad; Gumay, Jovana Renaldy; Sodik, Alfan Nur
Mitra Mahajana: Jurnal Pengabdian Masyarakat Vol. 6 No. 2 (2025): Volume 6 Nomor 2 Juli 2025
Publisher : LPPM Universitas Flores

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37478/mahajana.v6i2.5854

Abstract

Cultural advancement is an essential component of maintaining national identity, including the preservation of traditional sports that are being abandoned by the younger generation. This Community Service activity aims to increase students' knowledge and participation in traditional sports as a form of preserving local culture. The targets of the activity are students at three partner schools: SMAN 1 Gading Rejo, SMAN 2 Gading Rejo, and SMK Patria, who have not received direct learning about traditional sports. The implementation method includes education through interactive counselling, direct practice of various conventional games (engklek, running blocks, congklak, dompu), and provision of learning media such as modules, leaflets, and video documentation. Evaluation was carried out through participatory observation, questionnaires, and interviews with students and teachers. The results of the activity showed that 87% of students were new to and playing traditional games, while 92% expressed interest in playing them again. In addition, teachers welcomed this activity and saw its potential for integration into PJOK learning and extracurricular activities. It was concluded that the socialisation of traditional sports was effective in fostering cultural awareness and students' love for local heritage. It is hoped that this activity can be replicated in other schools as part of the strategy to advance Indonesian culture.
Pengaruh Edukasi Bahan dan Urgensi Penekanan Waktu terhadap Keputusan Pembelian Skincare "Sofia Skin Solution" pada Live Commerce dimediasi Perceived Value Shofiyah; Prasetiyo, Andri; Ahmar, Nurmala; Wirabrata, I Gede Made
PendIPA Journal of Science Education Vol 9 No 3 (2025): October
Publisher : UNIB Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/pendipa.9.3.826-835

Abstract

Live streaming is changing the digital marketing landscape, especially in the skincare industry. This research aims to examine the influence of ingredients education and time pressure on consumer purchasing decisions on “Sofia Skin Solution” products, with perceived value as a mediating variable. The research was conducted with a quantitative approach through a survey of 200 respondents active in the live streaming session. Data were analyzed using Structural Equation Modeling (SEM) based on Partial Least Squares (PLS). Results showed that ingredient education positively influenced perceived value (T-value = 6.104; p = 0.000), as did time pressure (T-value = 6.339; p = 0.000), with time pressure showing a slightly more dominant influence. Perceived value alone exerted the strongest influence on purchasing decisions (T-value = 5.512; p = 0.000), and was shown to fully mediate the relationship between ingredient education and purchasing decisions, as well as partially mediating the influence of time pressure on purchasing decisions. The direct effect of content education on purchasing decisions is not statistically significant, but is at the threshold, which crucially indicates the role of other factors such as brand image and host credibility. Findings confirm the importance of live streaming scripts that balance concise product information with short promotions to build trust and enthusiasm. Managerial implications suggest companies design short ingredient demonstrations followed by short offers to maximize conversions on live commerce platforms.
Systematic Literature Review: Pengaruh Permainan Tradisional Terhadap Kelincahan Siswa Sekolah Dasar Rachman, Fadlu; Prasetiyo, Andri; Rahmat, Ayi; Nuruhidin, Ahmad
Jurnal Porkes Vol 8 No 3 (2025): December: Article in Progress
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/porkes.v8i3.31872

Abstract

Traditional games contribute significantly to improving the agility of elementary school students. However, technological developments and lifestyle changes have led to a decline in physical activity among children. This study aims to systematically examine the impact of traditional games on the agility of elementary school students. The method used is a systematic literature review (SLR) by analyzing published research between 2019 and 2024 through Google Scholar, SINTA, and Publish or Perish. Of the 40 articles identified, 7 articles met the inclusion criteria. The results of the analysis showed that gobak sodor was able to increase agility by up to 67.5%, while bentengan increased agility by 9.7%. In addition, the games of lari balok, hadang, and sepak beleg were also proven to be effective in increasing students' agility. Compared to conventional exercises, traditional games are more interactive and can increase students' motivation to practice. In conclusion, traditional games can be applied as an effective strategy in physical education to develop the agility of elementary school students. Therefore, teachers, policymakers, and parents need to integrate traditional games into children's physical activities to support their motor development and fitness.
In-Silico Analysis And Molecular Dynamics Simulation Analysis of Sida rhombifolia Compounds as Candidate Antibacterial Agents Against Methicillin-Resistant Staphylococcus aureus firdaus, alshol; Herowati, Rina; Rahmawati, Ismi; Prasetiyo, Andri; Herman, Herman
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 2 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i2.646

Abstract

Antibiotic resistance has become a critical issue in global health, one of which is MRSA. The dynamic problem related to the increasing MRSA infections is clear evidence that the treatment and management of this disease have not been optimally resolved, requiring the development of effective antimicrobial agents against MRSA. An exploratory method was used to assess the antibacterial activity, interaction patterns, and stability of sidaguri compounds. A total of 15 potential compounds from sidaguri were docked onto four molecular targets: PBP2a (4JCN), MecR1 (609S), FtsZ (8HTB), and SCCmec (4FAK), using the molecular docking methods AutodockTools and PyMol, followed by analysis of the amino acid residue similarity of each test ligand. The molecular docking results predicted that the compounds with the best binding affinity and interaction patterns similar to the natural ligand for their respective molecular targets were quercetin, ecdysone, and 24-methylenecholesterol. The validation parameters are calculated from RMSD and RMSF based on the In-Silico predictions. MD simulations were performed using YASARA Dynamics. The MD simulation results showed that, from the RMSD and RMSF graphs of the MRSA target molecules, quercetin, ecdysone, and 24-methylenecholesterol exhibited binding stability close to that of the natural ligand. The predicted pharmacokinetic profiles show that all three compounds have a good ADMET profile, with optimal absorption potential, adequate distribution, appropriate metabolism, and relatively low toxicity, making them promising candidates for development as antibacterial drugs against MRSA
Formulasi Gel Kombinasi Ekstrak Buah Asam Gelugur (Garcinia atroviridis Griff. Ex T. Anderson) dan Daun Perilla (Perilla frutescens L. Britton) serta Uji Aktivitas Antijerawat dan Antioksidan Agustin, Vina; Taurhesia, Shelly; Prasetiyo, Andri
Jurnal Mandala Pharmacon Indonesia Vol. 11 No. 2 (2025): Jurnal Mandala Pharmacon Indonesia 
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v11i2.1059

Abstract

Penggunaan bahan-bahan alami sebagai agen antibakteri dan antioksidan topikal semakin mendapat perhatian, terutama dalam pengembangan formulasi untuk kulit berjerawat. Penelitian ini bertujuan untuk memformulasi dan mengevaluasi gel yang mengandung kombinasi ekstrak buah asam gelugur dan ekstrak daun perilla, serta untuk menilai aktivitas antibakteri, antioksidan, dan keamanan topikalnya. Tiga formulasi gel dibuat, gel dasar tanpa ekstrak (F0), gel dengan konsentrasi ekstrak optimal (F1), dan gel dengan konsentrasi ekstrak dua kali lipat (F2). Formulasi gel dievaluasi untuk sifat organoleptik, homogenitas, pH, daya sebar, viskositas, dan stabilitas fisik menggunakan cycling test. Aktivitas antibakteri diuji terhadap Cutibacterium acnes dan Staphylococcus epidermidis menggunakan metode difusi cakram, aktivitas antioksidan dinilai melalui uji penangkal radikal bebas DPPH. Uji iritasi kulit primer dilakukan pada kelinci albino untuk menentukan keamanan topikal gel. Hasil menunjukkan bahwa semua formulasi memenuhi karakteristik fisik dan stabilitas gel topikal yang dipersyaratkan. Sebelum dan sesudah cycling test stabil pada bakteri C.acnes F0 (0,00 mm), F1 (14,35 ± 0,32 mm), dan F2 (26,42 ± 0,08 mm). Sedangkan pada bakteri S.epidermidis F0 (0,00 mm), F1 (11,20 ± 0,24 mm), dan F2 (20,15 ± 0,05 mm). Nilai IC50 sebelum dan sesudah cycling test F0 (664,857 ppm), F1 (106,518 ppm menjadi 113,25 ppm), dan F2 (63,01 ppm menjadi 71,50 ppm). Uji iritasi menunjukkan skor 0,0 ± 0,0, yang menunjukkan bahwa gel aman untuk aplikasi topikal.
Education on the use of herbal medicine against Hypertension with Joyoboyo Health Community, Kediri Maulida Mazaya; Ratna Surya Alwi; Reza Alrayan; Esti Ambar Widyaningrum; Evi Kurniawati; Maratu Soleha; Mukh Fajar Nasrulloh; Andri Prasetiyo; Inggrid Tania
Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang Vol. 10 No. 2 (2025): May 2025
Publisher : University of Merdeka Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26905/abdimas.v10i2.14824

Abstract

Hypertension (high blood pressure) is a major global health concern. According to the National Health Profile (Riskesdas), it was reported that 450.126 cases occurred in Indonesia (2022), with 38.204 confirmed in Kediri Regency (2023), where hypertension has become the most common non-communicable condition in East Java, which was detected in the aged 15 years old. Generally, people still consume conventional medicine to lower their blood pressure. Contrarily, herbal medicine, often regarded as a complementary or alternative option. Thus, educational strategies for integrating herbal medicine into hypertension management are needed. In Kediri, the Joyoboyo health community plays an important role in spreading awareness about hypertension. During the community service activity, 61 Joyoboyo health cadre volunteers participated in these educational sessions to help them share accurate information with the wider community. These sessions covered topics such as correct dosage, possible interactions with prescription drugs, and the importance of evidence-based herbal use for treatment. These points were reinforced through discussion and supported by analyzing the recent clinical research. A statistical evaluation was conducted to assess the program's effectiveness. Overall, the results of this activity underline the need for a multidisciplinary approach combining traditional and scientific knowledge to optimize the management of hypertension. 
ANALISIS PENGARUH HARGA, KUALITAS PRODUK DAN KUALITAS PELAYANAN TERHADAP MINAT BELI ULANG DENGAN MODERASI STRATEGI PROMOSI PADA PENJUALAN PRODUK OVER THE COUNTER APLIKASI KIMIA FARMA MOBILE Ulfah, Meutia; Prasetiyo, Andri; Amyulianthy, Rafrini
Journal of Economic, Bussines and Accounting (COSTING) Vol. 9 No. 1 (2026): COSTING : Journal of Economic, Bussines and Accounting
Publisher : Institut Penelitian Matematika, Komputer, Keperawatan, Pendidikan dan Ekonomi (IPM2KPE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31539/n35m3g65

Abstract

Penelitian ini bertujuan menganalisis pengaruh harga, kualitas produk, dan kualitas pelayanan terhadap minat beli ulang produk Over The Counter (OTC) pada aplikasi Kimia Farma Mobile, dengan strategi promosi sebagai variabel moderasi. Konteks penelitian dilatarbelakangi oleh transformasi digital dalam industri farmasi dan tantangan yang dihadapi platform e-commerce kesehatan. Metode penelitian menggunakan pendekatan kuantitatif dengan sampel 384 pelanggan di seluruh Indonesia yang telah melakukan minimal dua kali transaksi. Pengumpulan data dilakukan melalui kuesioner online dengan skala interval 1-6. Analisis data menggunakan Structural Equation Modeling dengan pendekatan Partial Least Square (SEM-PLS) melalui software SmartPLS. Hasil penelitian menunjukkan bahwa harga, kualitas produk, dan kualitas pelayanan memiliki pengaruh signifikan terhadap minat beli ulang, dengan strategi promosi berperan sebagai variabel moderasi. Temuan mengungkapkan bahwa keberhasilan platform digital farmasi tidak hanya bergantung pada harga kompetitif, tetapi juga pada kualitas produk, layanan, dan strategi promosi yang efektif. Penelitian ini memberikan kontribusi teoritis dalam pengembangan literatur e-commerce farmasi dan kontribusi praktis bagi pengembangan strategi platform digital, khususnya dalam meningkatkan minat beli ulang konsumen.
Analisis Pengendalian Persediaan Obat Di Instalasi Farmasi Rumah Sakit Umum Proklamasi Kabupaten Karawang Dengan Metode ABC Nurul Laily Fadhillah; Andri Prasetyo; Rafrini Amyulianthy
Management Studies and Entrepreneurship Journal (MSEJ) Vol. 7 No. 3 (2026): Management Studies and Entrepreneurship Journal (MSEJ)
Publisher : Yayasan Pendidikan Riset dan Pengembangan Intelektual (YRPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37385/msej.v7i3.10479

Abstract

Manajemen persediaan obat di Rumah Sakit Umum Proklamasi dilakukan oleh Instalasi farmasi yang dimulai dari perencanaan, pengadaan, penerimaan dan penyimpanan. Menjamin ketersediaan obat adalah tanggung jawab yang harus dipenuhi oleh rumah sakit dengan menyesuaikan antara kebutuhan dengan anggaran yang tersedia. Penelitian ini bertujuan untuk melakukan analisis ABC berdasarkan nilai pemakaian dan nilai investasi. Penelitian ini merupakan penelitian deskriptif kualitatif dan kuantitatif dengan pengambilan data secara retrospektif. Pendekatan kuantitatif dengan analisis ABC dengan mempertimbangkan pemakain periode 2022 dan 2023 di Rumah Sakit Umum Proklamasi Karawang dan pendekatan kualitatif dilakukan dengan melakukan wawancara mendalam. Pengelolaan data menggunakan Microsoft Excel. Hasil analisis ABC berdasarkan nilai pemakaian tahun 2022 dari total item obat kelompok A memiliki persentase 32,50%; kelompok B 31,54% dan kelompok C 35,96% dan hasil nilai pemakaian tahun 2023 dari total item obat kelompok A memiliki persentase 28,92%; kelompok B 32,51% dan kelompok C 38,57%. Hasil analisis berdasarkan nilai investasi tahun 2022 dari total item obat kelompok A memiliki persentase 69,81%; kelompok B 20,14% dan kelompok C 10,05% dan hasil nilai investasi tahun 2023 dari total item obat kelompok A memiliki persentase 69,92%; kelompok B 20,00% dan kelompok C 10,09%.
Co-Authors Ade Yeni Aprilia Aey Fadilah, Yasin Agustia, Rini Agustin, VIna Ahmad Nuruhidin Alwie, Rakhmat Ramdhani Armanjaya, Satria Audrey, Cresentia Bambang Pontjo Priosoeryanto Bella Rofi Desi Nadya Aulena Dhani, Muhammad Esti Ambar Widyaningrum Esti Mumpuni Esti Mumpuni Esti Mumpuni, Esti Evi Kurniawati Evi Susanti Fadlu Rachman Fajar Ramadhan, Ziko firdaus, alshol Fitry Angger Pangestu Gayatri Indah Pramesti Gumay, Jovana Renaldy Hakim, Zainur Rahman Hutagaol, Lungguk Indriani, Aqilah Idelia Inggrid Tania Ismi Rahmawati Julian Rahmat Lalu Sanik Wahyu Fadil Amrulloh Lidya Luziana Lilik Sulastri Lilik Sulastri LUNGGUK HUTAGAOL Lungguk Hutagaol Luziana, Lidya M. Yogi Riyantama Isjoni Maratu Soleha Marlien Bokko Martati, Titiek Maulida Mazaya Maulinda, Elvi Sahri Mawijaya, Agus Megawati - Muhamad Yamin Muhammad Yamin Muhammad Zulfadhli, Muhammad Mukh Fajar Nasrulloh Mulatsari, Esti Nabila Prihantini Khairunnisa Natthawani, Amitta Nawasiah, Nana Novi Yantih Noviyantih, Noviyantih NURAINI HARMASTUTI Nurmala Ahmar Nuruhidin, Ahmad Nurul Laily Fadhillah Panca Bayu Chandra, Pra Pratamaa, Yuga R, Herowati Rachman, Fadlu Rachmi Ridho Rafrini Amyulianthy Rafrini Amyulianthy Rahmat, Ayi Ramadhan, Islami Al-Kaffah Ramadhani, Karina Natasya Ramani, Sofyan Ratna Surya Alwi Raymond R. Tjandrawinata Reza Alrayan Rhahmadini, Yahdi Thia Risna Rosmiyati Saeful Amin Saeful Amin Salsabila Adlina Saputra, Putri Windari Sarah Annisaa Nurwan Sari Dewi, Rika Sari, Felinda Sekar Harsti Rahmadhani Shaquille, Haikal Shirly Kumala Shofiyah Simanjuntak, Josua Donrio Simanjuntak, Vino Soaduon Siswandono, Siswandono Sodik, Alfan Nur Syamsudin Abdillah Syifa Aulia Taqwa, Iqbal Ananda Taurhesia, Shelly Ulfah, Meutia Utami, Santi Yanuarti Winana Kartika Dewi Wirabrata, I Gede Made Wiwi Winarti Yogaswara, Amira Thufailla Zahra, Nurulita Az Ziko Fajar Ramadhan, Ziko Fajar