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PENGARUH MEDIA VIDEO TERHADAP PENGETAHUAN IBU TENTANG TANDA BAHAYA PERDARAHAN PADA IBU HAMIL TRIMESTER 1 Fasimi, Rizki Handayani; Betty, Betty; Ardi, Ni Bodro; Ira, Ira
Edu Dharma Journal :Jurnal penelitian dan pengabdian masyarakat Vol 8, No 2 (2024): Edu Dharma Journal: Jurnal Penelitian Dan Pengabdian Masyarakat
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/edj.v8i2.923

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ABSTRACTThe Maternal Mortality Rate (MMR) is one of the indicators to measure the success of maternal health service efforts. Every day it is estimated that about 810 women die related to preventable pregnancy and childbirth. One of the efforts to increase pregnant women's understanding of pregnancy danger signs is by conducting social persuasion in the form of education. Research Method: the one used is pre-Experiment with one group pre-set post test design The instrument used is in the form of a Bleeding Hazard Questionnaire with a sample of 30 respondents with a purposive technique Objective: to find out the influence between the Independent variable and the Dependent variable, the data collected is collected using a questionnaire sheet. The number of samples in this study was 30 respondents of pregnant women in the 1st trimester at the Curugbitung Health Center.  Result: based on the Wilcoxon statistical test obtained a value (p-value 0.000 a, 0.05), it can be concluded that there is a significant influence of video media on the mother's knowledge about the danger signs of bleeding in pregnant women in the 1st trimester. Suggestion: From the results of this study, it is hoped that educational institutions can be used as an additional reference, especially maternity nursing in the provision of video media to obtain maternal knowledge about the signs of bleeding in pregnant womenABSTRAKAngka Kematian Ibu (AKI) merupakan salah satu indikator untuk mengukur keberhasilan upaya pelayanan kesehatan ibu. Setiap hari diperkirakan sekitar 810 wanita meninggal terkait kehamilan dan persalinan yang dapat dicegah. Salah satu upaya untuk meningkatkan pemahaman ibu hamil tentang tanda bahaya kehamilan yaitu dengan melakukan persuasi sosial berupa edukasi. Tujuan Penelitan : Penelitian ini adalah untuk mengetahui pengetahuan ibu hamil Trimester I tentang tanda bahaya kehamilan. Metode Penelitian : yang di gunakan adalah pre Eksperimen dengan rancangan one group pre tset post tes design Instrumen yang di gunakan berupa Kuesioner tanda bahaya perdarahan jumlah sample sebanyak 30 responden dengan teknik pengambilan purposive Tujuan : untuk menegetahui pengaruh antara variabel Independent dan variabel Dependen, data yang di kumpulakan menggunakan lembar kuesioner. Jumlah sampel pada penelitian ini sebanyak 30 responden ibu hamil trimester 1 di puskesmas curugbitung dari Hasil Penelitian : berdasarkan Uji statistik wilcoxon di peroleh nilai (p- value 0,000 a, 0,05) maka dapat di simpulkan ada pengaruh yang signifikan media video terhadap pengetahuan ibu tentang tanda bahaya perdarahan pada ibu hamil trimester 1. Saran : dari hasil penelitian ini di harapkan institusi pendidikan dapat di jadikan referensi tambahan khususnya ilmu keperawatan maternitas dalam pemeberian media video terhadapat pengetahuan ibu tentang tanda bahya perdarahan pada ibu hamil.
Relationship of Stromal Tumor Infiltrating Lymphocytes (STILs) with Grading Histopathology in Penis Squamous Cell Carcinoma Sihotang, Marisi Cintya Debby; Intan, T. Kemala; Alferraly, T. Ibnu; Betty, Betty; Soekimin, Soekimin; Delyuzar, Delyuzar
Majalah Patologi Indonesia Vol. 33 No. 2, Mei 2024
Publisher : Perhimpunan Dokter Spesialis Patologi Anatomik Indonesia (PDSPA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55816/mpi.v33i2.580

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ABSTRACT Background:Penile squamous cell carcinoma is the most common penile malignance found in the world. Assessment of stromal tumor infiltrating lymphocytes (STILs) associated with grading against penile squamous cell carcinoma can provide a potential prognostic picture and help determine the action. Method:Cross-sectional analytical study with 32 samples of histopathological preparations diagnosed as penile squamous cell carcinoma at H. Adam Malik Hospital Medan. The assessment of stromal TILs was carried out by assessing the number of lymphocyte inflammatory cells in the peritumoral stroma and then determined the assessment score, zero score no lymphocytes (minimum), score one found 0-10% lymphocytes (moderately), score two found 20-40% lymphocytes (massive) , score three found 50-90% lymphocytes. Grading assessments are categorized into grade I (well differentiated), grade II (moderately differentiated), and grade III (poorly differentiated). Result:The most grading found was grade II (43.8%) and the most STILs found were score three (50.0%). There is a significant relationship between grading and STILs in penile squamous cell carcinoma (p value=0.0001) i.e. the higher the STILs score , the lower the tumor grade. Conclusion:There is a relationship between STILs and histopathological grading in Penile Squamous Cell Carcinoma so that it can be used as an indikasi prognosis in patients with penile squamous cell carcinoma.
Immunohistochemistry Expression Gata3 Based on Subtypes of Ovarian Carcinoma at Haji Adam Malik General Hospital Medan 2019-2021 Alamanda, Intan Nefia; Betty, Betty; Delyuzar, Delyuzar; Laksmi, Lidya Imelda; Chrestela, Jessy; Soekimin, Soekimin
Majalah Patologi Indonesia Vol. 33 No. 3, September 2024
Publisher : Perhimpunan Dokter Spesialis Patologi Anatomik Indonesia (PDSPA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55816/mpi.v33i2.604

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Background Ovarian carcinoma is a cancer with high mortality in women and although comprehensive management with surgery and chemotherapy at an advanced stage, the resistance rate is still low. GATA3 contributes to the progression of malignancy and its expression is one of the predictors in some malignancies, but the results are mixed in ovarian carcinoma. High GATA3 expression is associated with the aggressiveness of tumor growth and poor prognosis of ovarian carcinoma.   Methods This research is an cross-sectional descriptive-analytical study with 33 histological specimens diagnosed with ovarian carcinoma from medical records/archives at H. Adam Malik Hospital Medan. Each sample specimen was stain with GATA3, and several various histopathological subtypes of ovarian carcinoma.   Results From a total of 33 samples, 14 samples were serous carcinoma, 6 samples were mucinous carcinoma, 7 samples were endometrioid carcinoma, and 6 samples were clear cell carcinoma. GATA3 was expressed in 42.5% of serous carcinoma. Positive expression of GATA3 is mostly found in advanced ovarian carcinoma, older age, and histopathological type of serous carcinoma.    Conclusion Immunohistochemistry GATA3 expression was expressed in 42.4% of serous carcinoma, 21.2% in endometrioid carcinoma, 18.2% in clear cell carcinoma, and 18.2% in mucinous carcinoma.   Keywords: ovarian carcinoma, GATA3, immunohistochemistry
The Correlation of Light Chain 3B Immunohistochemical Expression with Histopathological Grading in Colorectal Adenocarcinoma Fiandani, Fatma; Betty, Betty; Delyuzar, Delyuzar; Laksmi, Lidya Imelda; Lukito, Joko S.
Majalah Patologi Indonesia Vol. 33 No. 3, September 2024
Publisher : Perhimpunan Dokter Spesialis Patologi Anatomik Indonesia (PDSPA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55816/mpi.v33i3.610

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Background Colorectal cancer ranks third highest of all malignancies worldwide and ranks fourth out of the 10 most common cancers encountered in Indonesia. More than 90% of colorectal cancers are adenocarcinoma type. The mechanism of autophagy has a dual role in tumorigenesis, namely as a tumor suppressor and as a tumor promoter. Microtubule-associated protein 1 light chain 3B (LC3B) is one of the widely used autophagy markers. The role of autophagy requires further research so that LC3B can be considered as one of the predictors of prognosis, especially in colorectal adenocarcinoma. The aim of this research is to determine the correlation of Light Chain 3B immunohistochemical expression with histopathological grading of colorectal adenocarcinoma. Methods Cross-sectional analytic study of 41 samples diagnosed with colorectal carcinoma at H. Adam Malik General Hospital Medan. Staining was performed using a polyclonal antibody rabbit Light Chain 3B immunohistochemistry (GeneTex) which would appear positive in the cytoplasm of tumor cells at a dilution of 1: 500. LC3B expression was assessed semiquantitatively with low and high expression categories. Data analysis was tested with the Spearman correlation test. Results LC3B immunohistochemical expression has a very strong correlation with the histopathological grading of colorectal adenocarcinoma and in a positive direction where the higher the colorectal adenocarcinoma grade, the higher the LC3B immunohistochemical expression, and vice versa (p=0,0001; r=0,763). Conclusion There was a significant relationship between LC3B immunohistochemical expression and histopathological grading of colorectal adenocarcinoma.
Correlation Ki67 Expression With peritumoral budding Tumor Index In the Case of Squamous Cell Carcinoma Cervix NOS And Adenocarcinoma Cervix NOS Wardini, Indah Astri; Alferraly, T. Ibnu; Chrestela, Jessy; Betty, Betty; Intan, T. Kemala; Lubis, H. M. Nadjib Dahlan
Majalah Patologi Indonesia Vol. 33 No. 3, September 2024
Publisher : Perhimpunan Dokter Spesialis Patologi Anatomik Indonesia (PDSPA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55816/mpi.v33i3.611

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Background Cervical cancer is a neoplasm in the cervix due to abnormal cells that damage the surrounding tissue. Cervical cancer from squamous cells is called squamous cell carcinoma cervix NOS and that from glands is called adenocarcinoma cervix NOS. The prognostic of both can be assessed by tumor budding and Ki67 immunohistochemistry, tumor budding is a tumor bud which is ≤ 5 cells in a cluster that grows in front of the parent tumor and immunohistochemistry Ki67 is a labile nonhistone nuclear protein which is expressed in the G1, S, G2 and M phases of the cycle cell.   Method This research is an analytical type of research that aims to find out the relationship between Ki67 expression and the peritumoral budding tumor index compared to cases of squamous cell carcinoma cervix NOS and adenocarcinoma cervix NOS with 36 paraffin block samples diagnosed with squamous cell carcinoma NOS and adenocarcinoma NOS at HAM Hospital. Medan. Assessment method of Ki67 expression where low expression (<20%) and high expression (≥20%). Assessment of peritumoral budding tumors in both cases was said to be low buds if < 5 buds and high buds if ≥ 5 buds. Results This study provides a significant appearance (p-value 0.0001) which means that peritumoral budding tumors with HE staining can be accepted as a measuring tool for assessing cervical cancer in addition to assessment using immunohistochemistry Ki67 which is generally used in the prognostic assessment of cervical cancer. Conclusion Assessment in this case can consider peritumoral budding tumor assessment to determine prognostic in cases of squamous cell carcinoma NOS and cervical adenocarcinoma NOS, if Ki67 immunohistochemistry is not available.
The Correlation between Matrix Metalloproteinase-9 (MMP-9) Immunohistochemical Expression and Histopathological Subtypes of Basal Cell Carcinoma: A Correlation between Matrix Metalloproteinase-9 (MMP-9) Immunohistochemical Expression and Histopathological Subtypes of Basal Cell Carcinoma Aisyah, Siti; Intan, T. Kemala; Alferraly, T. Ibnu; Betty, Betty; Soekimin, Soekimin; Laksmi, Lidya Imelda
Majalah Patologi Indonesia Vol. 33 No. 2, Mei 2024
Publisher : Perhimpunan Dokter Spesialis Patologi Anatomik Indonesia (PDSPA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55816/mpi.v33i2.644

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ABSTRACT Background Basal cell carcinoma (BCC) is a non-melanocytic skin cancer originating basal layer of the epidermis and/or hair follicles that shows an increasing global incidence. Disease growth is slow, rarely metastasizes but has the ability to invade and destroy deeper surrounding tissues. Low mortality, but high morbidity. Matrix metalloproteinases are enzymes that can degrade various extracellular matrix components. In skin, MMP-9 expression may be increased by prolonged ultraviolet exposure. UV radiation is one of the causes of BCC. Method Analytic study with a cross sectional approach on 40 surgical samples diagnosed as BCC and then performed with MMP-9 immunohistochemical staining. The data obtained were processed with statistical software and the relationship between the immunohistochemical expression of MMP-9 with histopathological subtypes of basal cell carcinoma was used the Somers'd statistical test. Results The expression of MMP-9 in the lower risk BCC group with the weakest expression was 37.5%, the most common nodular BCC subtype was 27.5%. The higher risk BCC group with the strongest expression was 20.0%, the most common infiltrating BCC was 17.5%. There was a significant relationship between the immunohistochemical expression of MMP-9 with histopathological subtypes of basal cell carcinoma, p value <0.0001 (p<0.05). Conclusion This study proves that there is a significant relationship between the expression of MMP-9 with histopathological subtypes of basal cell carcinoma, so it can be considered as an additional marker to predict the recurrence.
Hubungan Ekspresi Transforming Growth Factor-β1, Fibroblast Activated Protein, pola Tumor-Associated Collagen Signature dan derajat Tumor-Infiltrating Lymphocytes terhadap Grading International Society of Urological Pathology pada Clear Cell Renal Cell Ca Kharismawaty, Dina; Delyuzar, Delyuzar; Betty, Betty; S Lukito, Joko; Chrestella, Jessy
Majalah Patologi Indonesia Vol. 32 No. 1, Januari 2023
Publisher : Perhimpunan Dokter Spesialis Patologi Anatomik Indonesia (PDSPA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55816/mpi.v32i1.568

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BackgroundClear cell renal cell carcinoma (ccRCC) is a very aggressive cancer and is often diagnosed at an advanced stage. The stromal component around the tumor is thought to have contributed greatly to these findings.MethodsAnalytical study with cross sectional design on 23 histological specimens diagnosed by ccRCC based on data from medical records/pathology archives in 2012-2021. Each specimen was stained with hematoxylin and eosin, TGF-β and FAP immunohistochemistry and Masson's trichrome. Fisher's exact test (p<0.05) was used to assess the association between the expressions of all variables with the ISUP grading.ResultsMost cases were high grade ccRCC (87%) samples, of which 73.9% samples expressed strong TGF-β, 82.7% samples expressed positive intratumoral FAP, 78.3% samples expressed positive stromal FAP, 47.8% showed a TACS-3-pattern, 56.5% of samples with positive stromal TILs and 47.8% of samples with negative intratumoral TILs. There was no significant association between all of these variables and the ISUP grading of the ccRCC (p<0.05).ConclusionExpression of TGF-β1, intratumoral and stromal FAP, TACS pattern and the degree of intratumoral and stromal TILs were not significantly associated with ISUP grading in ccRCC.
Improving the Management of School Operational Assistance (SOA) Grants Through Expenditure Governance Abdullah, M. Ikbal; Masdar, Rahma; Karim, Fikry; Din, Muhammad; Zahra, Femilia; Furqan, Andi Chairil; Munawarah, Munawarah; Iqbal, Muhammad; Masruddin, Masruddin; Hadi, Suryadi; Betty, Betty; Meldawati, Lucyani; Naida, Nasrun; Megawati, Nani
Economic and Business Horizon Vol. 1 No. 3 (2022): September
Publisher : LifeSciFi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54518/ebh.1.3.2022.71

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School Operational Assistance (SOA) is a government program that provides funding for personnel operational costs for basic education units as implementing compulsory learning programs. The SOA program policy, programmed in elementary and junior high schools, is one form of policy implementation with the aim of equity and improving the quality of basic education. Therefore, SOA funds must be managed properly and carried out orderly and responsibly. The management of SOA funds is the principal’s responsibility, assisted by the SOA Treasurer. However, in practice, there was a misappropriation of SOA funds. The misappropriation of SOA funds was found to several factors that lead to the achievement of the objectives of managing funds have not been achieved, including planning aspects, implementation aspects, and accountability aspects. In the implementation aspect, it was found that, basically, all use of the budget was in accordance with the technical guidelines. Still, the lack of socialization among parents caused many parties to misunderstand the problem of SOA funds, even though socialization is a very important stage in determining the success and smooth implementation of the program. In accountability, not a few schools have difficulty compiling financial reports because not all schools have competent personnel in their fields. Furthermore, in the 2021 Supreme Audit Agency’s (BPK/Badan Pemeriksa Keuangan) audit report, there are findings obtained by Supreme Audit Agency, one of which is that there are weaknesses in the administration and accountability of School Operational Assistance funds (SOA) in Tojo Una Una, Central Sulawesi, Indonesia. Therefore, it is necessary to do service in the form of socialization related to the administration of the SOA Fund Treasurer, which will be framed in an effective communicative and relaxed manner so that it can provide a stimulus to participants so that they can comprehensively understand administrative technicalities in accordance with the latest developments in the Regulation of the Minister of Internal Affairs No. 24 of 2020 concerning administration for the management of SOA grants.
Corruption Prevention: Government Internal Control System and Organizational Culture as Moderation Rusli, Riswandi; Yamin, Nina Yusnita; Kamase, Haryono Pasang; Betty, Betty
Accounting Studies and Tax Journal (COUNT) Vol. 2 No. 1 (2025): Accounting Studies and Tax Journal (COUNT)
Publisher : Penelitian dan Pengembangan Ilmu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62207/pshys616

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This study examines and analyzes the effect of government internal control systems and organizational culture interaction on corruption prevention. This research was conducted in village governments in Marawola, Dolo, and Sigi Biromaru sub-districts, Central Sulawesi, involving 150 village government officials as respondents. This research uses quantitative methods with primary data in the form of questionnaires. SmartPLS 4.0 was used as an analysis tool. The results found that a strong internal control system, as indicated by a healthy control environment and regular monitoring activities, is effective in preventing corruption. An organizational culture that emphasizes open communication and information is proven to strengthen corruption prevention efforts. However, the results of this study also show that an organizational culture that does not support the separation of duties and authorities will weaken corruption prevention efforts. These findings suggest that building a strong system is not enough, it is important to build a culture that supports transparency and accountability.
Strategi Peningkatan Kualitas Pelaporan Keuangan dan Akuntabilitas Kinerja Instansi Pemerintah Daerah: Studi Badan Pengelolaan Keuangan dan Aset Daerah (BPKAD) Kota Palu Alannuwari, Alannuwari; Masdar, Rahma; Din, Muhammad; Betty, Betty
Jurnal Pendidikan Tambusai Vol. 9 No. 1 (2025)
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai, Riau, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jptam.v9i1.26269

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Latar belakang penelitian ini mencerminkan peran krusial Badan Pengelolaan Keuangan dan Aset Daerah Badan Pengelolaan Keuangan dan Aset Daerah (BPKAD) dalam mengelola keuangan daerah, menekankan perlunya meningkatkan kualitas pelaporan keuangan dan akuntabilitas kinerja. Metode penelitian yang digunakan adalah kualitatif deskriptif dengan fokus pada implementasi Standar Akuntansi Pemerintahan (SAP) dan pelatihan Sumber Daya Manusia (SDM) di BPKAD Kota Palu. Subjek penelitian melibatkan pejabat dan staf bidang akuntansi di BPKAD, dengan objek penelitian mencakup proses pelaporan keuangan, penerapan SAP, dan pelatihan SDM. Hasil penelitian menunjukkan bahwa penerapan SAP telah membawa dampak positif pada transparansi, keakuratan, dan ketepatan waktu pelaporan keuangan di BPKAD Kota Palu. Pelatihan SDM juga memainkan peran penting dalam meningkatkan pengetahuan dan keterampilan staf di bidang akuntansi dan keuangan. Sinergi antara SAP dan pelatihan SDM menciptakan lingkungan yang mendukung peningkatan kualitas pelaporan keuangan dan akuntabilitas kinerja. Opini "Wajar Tanpa Pengecualian" (WTP) dari Badan Pemeriksa Keuangan (BPK) menjadi indikator keberhasilan, namun tantangan SDM, terutama perubahan bendahara, masih menjadi fokus utama untuk diperbaiki. Kesimpulan studi ini menggarisbawahi bahwa integrasi strategi SAP dan pelatihan SDM efektif dalam meningkatkan kualitas pelaporan keuangan dan akuntabilitas kinerja di BPKAD Kota Palu. Sementara pencapaian positif telah terlihat, tantangan SDM tetap menjadi area perbaikan yang perlu perhatian lebih lanjut untuk mencapai kesinambungan dan peningkatan berkelanjutan di masa mendatang.
Co-Authors Abda Abda Abdul Hakim Abdul Kahar Abdullah, M. Ikbal Adelse Prima Mulya Adelse Prima Mulya, Adelse Adfiyani Fadjar Alamanda, Intan Nefia Alannuwari, Alannuwari Alferraly, Ibnu Alferraly, T. Ibnu Alifia, Eva Putri Angkasa, Dennis Astuti, Vina Catur Aulia, Windy Nova Ayamah, Ayamah Bitaria Febrawati, Eka Chrestela, Jessy Chrestella, Jessy Dahlan, Nadjib Delyuzar, Delyuzar Erwinsyah Erwinsyah Femilia Zahra Femilia, Femilia Fiandani, Fatma FIDROTIN AZIZAH Fikry Karim Fikry, Fikry Fitri Desimilani, Fitri Desimilani Furqan, Andi Chairil Ginting, Rehulina Gita Ayuningtyas Gugun Mangesa Gunarsa, Arif Halim, Andrian Harahap, Sefparina Harnida Wahyuni Adda Haryono Pasang Kamase Hasibuan, Arie Widiansyah Indrisari, Rahayu Intan, T. Kemala Ira Ira, Ira Iskandar, Arik Kaluku, Aditya D Ketty Suketi Kharismawaty, Dina Kristiyowati, Anis Dwi Laksmi, Lidya Imelda Latifah Sukmawati Yuniar Lestari, Ni Komang Sindy Listiyaningsih, Listiyaningsih Lubis, H. M. Nadjib Dahlan Lucyani, Meldawati Lukito, Joko S. M. Iqbal A Mariedina, Causa Trisna Marlon, Marlon Marpaung, Fenny Krisna Masriana Masriana, Masriana Masruddin Megawati, Nani Meilita, Findi Meldawati, Lucyani Michelle, Michelle Miluana, Miluana Muhammad Din Munawarah Munawarah, Munawarah Mustamin Mustamin Nadhira Afdalia, Nadhira Nasrun Naida Ni Bodro Ardi Nina Yusnita Yamin Nur Hasanah Poddar, Sandeep Puji, Lela Kania Rahsa Putra, Yosua Angkasa Putri Handayani Putri, Amelia Hamdani Putri, Arla Amalia Putri Putri, Marissa Yolanda Rafika Dora Wijaya Rahma Masdar Rahmawati, Rahmawati, Ramadhan, Sahrul Rezeki, Dewi Sri Ridwan, Ridwan Rinawati Kasrin Rinawati Kasrin Rinawati Kasrin Rinawati Kasrin, Rinawati Kasrin Rita Dwi Pratiwi Rizki Handayani Fasimi Rizki, Diana Rosita Rosita Rudy Usman Rusli, Riswandi S Lukito, Joko S. Lukito, Joko Saleh, Fadli Moh. SALMAN FARIS Sandra Arifin Aziz Sansuwito, Tukimin bin Sayyidah, Sayyidah Shafira, Anggriana Sihotang, Marisi Cintya Debby Siregar, Denny Rifsal Siti Aisyah Siti Novy Romlah Soekimin Soekimin, Soekimin Sri Wahyuni Suriati Tirawani Suryadi Hadi Tirawani, Suriati TITA HARDIANTI Unayah, Maelia Uswatun Hasanah Utami Utami Vandi Saputra Very, Very Vike Dwi Hapsari Vira, Natalin Wardini, Indah Astri Widyakusuma, Annastry Yuldi Mile Zindy Kaludia