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All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Jurnal Berkala Epidemiologi STOMATOGNATIC- Jurnal Kedokteran Gigi ODONTO Dental Journal Dentino: Jurnal Kedokteran Gigi Berkala Kedokteran Dental Journal (Majalah Kedokteran Gigi) Padjadjaran Journal of Dentistry Dentin Jurnal Insan Farmasi Indonesia Jurnal Pengabdian Ilung (Inovasi Lahan Basah Unggul) Odonto dental journal
Maharani Laillyza Apriasari
Departement Of Oral Medicine, Faculty Of Dentistry, Lambung Mangkurat University
Agriculture, Biological Sciences & Forestry Arts Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Energy Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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THE EFFECT OF MAULI BANANA STEM EXTRACT GEL (Musa acuminata) APPLICATION IN CONCENTRATION OF 37.5% ON EPITHELIAL THICKNESS (Research report) Monica Thiodora Limay; Maharani Laillyza Apriasari; Irham Taufiqurrahman
Dentino : Jurnal Kedokteran Gigi Vol 4, No 1 (2019)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v4i1.6166

Abstract

Background: Injury is a state of damage or loss of tissue that can be caused by physical action. Plants that can be used in wound healing is mauli banana stem.  Mauli banana stem extract gel concentration of 37.5% contains tannins and saponins which have potential as immunomodulators. Previous research has stated that mauli banana stem extract gel concentration of 37.5% can cure traumatic ulcers. Purpose: To prove the effect of mauli banana stem (Musa acuminate) extract gel application in concentration of 37.5% on epithelial thickness in wistar rat’s (Rattus novergicus) oral mucosa lesions  on the 7th day of wound healing process. Method and material: This research was a true experimental research with posttest only control group design. It used 3 treatment groups consisted of a group which was given mauli banana stem (Musa acuminata) extract gel concentration of 37.5%, hydroxypropyl methylcellulose gel (HPMC) and patent drug containing Aloe vera extract gel. Results: The mean of  epithelial thickness in the wound healing process on the 7th day in treatment group, negative control group, and positive control grou were 119.1857 μm, 82.4563 μm, and 90,5937μm respectively . One-way Anova's test showed that there is a difference between the result of the treatment groups. Post hoc LSD test showed significant difference of epithelial thickness between mauli banana stem extract concentration of 37.5% group and hydroxypropyl methylcellulose gel (HPMC) group. There is no significant differerence between mauli banana stem extract gel concentration of 37.5% group and the patent drug containing Aloe vera extract gel group. Conclusion: The application of mauli banana stem extract gel in concentration of 37.5% can increase epithelial thickness in oral mucosa on the 7th day of wound healing process
THE EFFECT OF TOPICAL TOMAN (Channa micropeltes) FISH EXTRACT ON THE NUMBER OF NEUTROFIL CELLS IN DIABETES MELITUS WOUND HEALING (In Vivo Study on Male Wistar (Rattus novergicus) Rat’s Back) Annisa Vara Nurdianty; Maharani Laillyza Apriasari; Amy Nindia Carabelly
Dentino : Jurnal Kedokteran Gigi Vol 4, No 2 (2019)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v4i2.7059

Abstract

Backgrounds: Diabetes mellitus forges the wound healing process to last longer. Toman fish which contains albumin and omega-6 fatty acid is proven to to enhance wound healing process in this systemic condition. Patients who suffer from diabetes mellitus retain high neutrophil number. Omega-6 fatty acids contained in Toman fish can decrease the number of  neutrophil cells. Objectives:  To prove the effect of Toman fish (Channa micropeltes) extract at 20% concentration topically on the number of neutrophil in diabetes mellitus-induced Wistar Rat (Rattus novergicus) injuries on day 4, 8 and 14.  Methods: This research was a true experimental study with posttest-only and control group with complete random design. Thirty six male Wistar rats (Rattus novergicus) was divided evenly for three treatments comprised of negative control given BR2 comfeed, positive control treated with Haruan fish (Channa striata) extraxt at 10% concentration topically and treatment group given with Toman fish (Channa micropeltes) extract at 20% concentration topically. Results: The data was analyzed using One Way ANOVA and was presenting the result of the 4th day (p=0.000), 8th day (p=0.001) and 14th day (p=0.000). Post-hoc Least Significant Difference (LSD) showed that p value was less than 0.05 which means that there was a significance difference in the mean of all treatment groups. Conclusion: Toman fish (Channa micropeltes) extract possesses the capacity in decreasing the number of neutrophil on 4th, 8th and 14th day in diabetic wound healing of Wistar Rat (Rattus novergicus).
EFFECT OF 25%, 37,5% AND 50% MAULI BANANA (Musa acuminata) STEM EXTRACT AS MOUTHWASH ON COLOR STABILITY OF BULK FILL RESIN COMPOSITE Dewi Puspitasari; Maharani Laillyza Apriasari
Dentino : Jurnal Kedokteran Gigi Vol 3, No 2 (2018)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v3i2.5373

Abstract

Background:. Mauli banana stem extract can be used as an herbal mouthwash. The use of mouthwash in the oral cavity may be in contact with tissue mucosa, dentition and restorations. Bulk-fill composite resin is currently used as restoration. Composite resins have a tendency to experience discoloration. One of the factors that may cause color changes in composite resins is the use of mouthwash. Purpose: to analyze the effect of 25% mauli banana stem extract, 37.5% and 50% as a mouthwash to the color change in bulk-resin composite resin restoration. Method: This study was purely experimental pretest and posttest group design. Composite resin specimens was fabricated accordingISO 4791: 2000 specifications, molds of 17 mm in diameter and 1 mm thickness. There were 5 treatment groups that composite resin samples were immersed in the distilled as negative control, 25% mauli banana extract solution, 37.5% and 50% and chlorhexidine gluconate as positive control. Data analysis used one way Annova statistical test. Result: there were significant differences in the composite resin group immersed in aquades, chlorhexidine and mauli banana stem extracts, but there was no significant difference in the mauli banana extract stem at different concentrations. Conclusion: mauli banana stem extract causes the highest color change in composite resin when used as a mouthwash.
Peroxide alkaline for cleansing the baby bottle nipple to prevent oral thrush relaps Maharani Laillyza Apriasari
Dental Journal (Majalah Kedokteran Gigi) Vol. 46 No. 2 (2013): June 2013
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (843.847 KB) | DOI: 10.20473/j.djmkg.v46.i2.p75-79

Abstract

Background: Oral candidiasis is the most prevalent opportunistic infection affecting the oral mucosa. A number of predisposing factors have the capacity to convert Candida from the normal commensal flora to a pathogenic organism. Oral candidiasis is divided into primary and secondary infection. The primary infections are restricted to the oral and perioral sites, where as secondary infections are accompanied by sistemic mucocutaneous manifestation. Oral thrush is one of the candidiasis primary infection. Some presdiposing factors of oral thrush are neonatal, old people, or where oral microflora is disturbed by the treatment with broad spectrum antibiotics. Final diagnosis is determined by fungal culture examination, although through clinical examination oral thrush can be determined by swabbing the white pseudomembran. Purpose: This case report presents about the importance of using the antiseptic cleanser for baby bottle nipple to prevent oral thrush relaps and shows about peroxide alkaline as the alternatif of antiseptic cleanser for baby bottle nipple that can substitute chlorhexidine gluconat 0.2%. Case: A baby girl, 15 months old, when she was suffering influenza the pediatry gave amoxycillin 125 mg three times a day for ten days. Then the white plaque appeared on her dorsum of tongue. The therapy was Gentian Violet 1% four times a day for ten days was applied on dorsum of the tongue. The patient was suspected to suffer alergy reaction after using nistatin oral suspension four times a day had applied for 1 day. The instruction was doing sterilization for the baby bottle nipple in boiling water. Three days after the baby was cured, the white plaque was appeared on upper n lower lips mucous. Case management: The diagnosis was Oral thrush. The therapy was Gentian violet 1% four times a day for ten days that applied on upper and lower lips mucous. The instruction was doing the sterilization for baby bottle nipple in denture cleanser contain peroxide alkaline for five minutes, then it was washed with antiseptic soap, and soaked it in boiling water. Conclusion: The baby bottle nipple sterilization on the case of Oral thrush can not only by boiling in the water, but it must be keep in the antiseptic solution before boiled in the water. It was for preventing oral thrush relaps.Latar belakang: Kandidiasis rongga mulut merupakan infeksi opurtunistik yang sering terjadi pada mukosa mulut. Banyak faktor predisposisi yang menyebabkan Candida yang awalnya merupakan flora normal dalam rongga mulut berubah menjadi organisme patogen. Kandidiasis rongga mulut dibagi menjadi infeksi primer dan sekunder. Infeksi primer terjadi pada rongga mulut dan sekitarnya, sedangkan infeksi sekunder akan diikuti oleh manifestasi mukokutan secara sistemik. Oral thrush adalah salah satu dari infeksi primer candidasis. Beberapa faktor predisposisinya adalah pada bayi, orang tua atau microflora rongga mulut terganggu karena pemakaian jenis antibiotik spektrum luas. Diagnosis akhir didapatkan dari pemeriksaan kultur jamur, meskipun diagnosis dapat ditegakkan dengan pemeriksaan klinis melalui hapusan lesi pesudomembran putih. Tujuan: Laporan kasus ini tentang pentingnya penggunaan antiseptik untuk sterilisasi dot botol bayi untuk mencegah kekambuhan oral thrush dan menunjukkan alkalin peroxida sebagai alternatif bahan antiseptik untuk sterilisasi dot botol bayi, yang mampu mengganti Klorheksidin glukonat 0,2%. Kasus: Pasien adalah bayi perempuan usia 15 bulan, selama sakit batuk pilek mendapat obat dari dokter spesialis anak amoxycillin 125 mg yang diberikan 3 kali sehari selama 10 hari. Selanjutnya tampak plak putih pada lidah. Terapi yang diberikan adalah Gentian Violet 1% yang oleskan 4 kali sehari selama 10 hari pada dorsum lidah. Hal ini disebabkan pasien diduga mengalami alergi setelah diberi nistatin suspensi 4 kali sehari. Instruksi yang dianjurkan adalah menyeteril dot botol bayi dalam rebusan air. Setelah sembuh, 3 hari kemudian muncul lagi plak putih pada mukosa bibir atas dan bawahnya. Tatalaksana kasus: Pasien didiagnosis menderita oral thrush. Terapi yang diberikan adalah Gentian Violet 1% diaplikasikan 4 x 1 selama 10 hari pada mukosa bibir atas dan bawah. Instruksi yang diberikan adalah untuk menyeteril dot botol bayi dengan pembersih gigi tiruan yang mengandung alkalin peroksida selama 5 menit, kemudian dicuci dengan sabun mandi antiseptik, dan direbus dalam air. Simpulan: Sterilisasi pada bottle nipple pada pasien anak dengan oral thrush tidak dapat dilakukan dengan hanya merebus dalam air saja, melainkan harus merendam dengan cairan antiseptik terlebih dahulu sebelum direbus dalam air. Hal ini untuk mencegah terjadinya kekambuhan pada Oral thrush.
The management of chronic traumatic ulcer in oral cavity Maharani Laillyza Apriasari
Dental Journal (Majalah Kedokteran Gigi) Vol. 45 No. 2 (2012): June 2012
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (779.882 KB) | DOI: 10.20473/j.djmkg.v45.i2.p68-72

Abstract

Background: The traumatic ulcer is one of the most common oral mucosal lesions. The etiology of traumatic ulcer may result from mechanical trauma, as well as chemical, electrical, or thermal stimulus, may also be involved in addition, fractured, malposed, or malformed teeth. The clinical manifestation of traumatic ulcer are ulcer, have a yellowish floor, fibrinous center, red and inflammatory margin without induration. Purpose: The purpose of this case report is to present how to manage the patient with the chronic traumatic ulcer in oral cavity. Case: This case report is about the patient with chronic ulcer in oral cavity. Intra oral examination showed on the right tongue margin appeared the major ulcer, single, diameter 1,5 cm, pain, white color, induration and irreguler margin around the ulcer. The patient had been suffering it for 5 months. She had come to a lot of dentist and the oral maxillofacial surgery, but they could not heal the ulcer. The dental occlusion of the patient, especially 17 and 47 then 15 and 45 teeth was looked bitten the right tongue. It underlied to get the clinical diagnosis as the chronic traumatic ulcer. Case management: The main therapy of traumatic ulcer is eliminiting the etiology factor, so that decided to do teeth extraction 45 and 47 that was looked linguversion position on 45 degrees. Before doing the teeth extraction, the patient was referred to take complete blood count (CBC), blood glucose examination and biopsy. The monitoring of the ulcer must be done until 2 weeks after the teeth extraction. If the lesion was persistent, it is suspected as malignancy. Conclusion: It can be concluded that the main management of chronic traumatic ulcer in oral cavity is removing the etiology factors. If the ulcer is still persistent after 2 weeks from the etiology factor had been removing, it is suspected as the malignancy that is needed biopsy examination to get the final diagnosis.Latar belakang: Ulkus traumatikus adalah salah satu lesi pada mukosa mulut yang sering terjadi. Penyebab ulkus traumatikus adalah adanya trauma mekanik, seperti kimia, elektrik atau suhu, selain itu dapat pula terjadi karena fraktur, malposisi atau malformasi gigi. Manifestasi klinis dari ukus traumatikus adalah ulser, dasar berwarna kuning, pada bagian tengah tampak fibrin, pinggiran berwarna merah dan mengalami keradangan tanpa adanya indurasi. Tujuan: Tujuan dari laporan kasus ini adalah untuk melaporkan bagaimana penatalaksanaan pasien dengan ulkus traumatikus kronis pada rongga mulut. Kasus: Kasus ini melaporkan tentang ulser kronis yang terjadi pada rongga mulut. Pemeriksaan pada rongga mulut menunjukkan pada pinggir lidah kanan tampak ulser mayor, tunggal, diameter 1,5 cm, sakit, berwarna putih, pinggiran sekitarnya tampak indurasi dan tidak teratur. Ulser terjadi selama 5 bulan. Pasien mengunjungi banyak dokter gigi dan spesialis bedah mulut, tetapi ulser tidak dapat disembuhkan. Pada saat pasien oklusi, pada gigi, 17 dengan 47 serta gigi 15 dengan 45 tampak lidah sebelah kanan tergigit. Hal ini yang mendasari diagnosis sementaranya adalah ulkus traumatikus kronis. Tatalaksana kasus: Penanganan utama dari ulkus traumatikus adalah menghilangkan faktor penyebab, oleh sebab itu dilakukan ekstraksi pada gigi 45 dan 47 yang terlihat posisi linguoversi 45 derajat. Sebelum gigi-gigi tersebut diekstraksi, pasien dirujuk untuk melakukan pemeriksaan darah lengkap, gula darah dan biopsi. Ulser harus tetap dimonitor sampai 2 minggu pasca ekstraksi. Jika lesi menetap, maka ini diduga Squamous Cell Crsinoma. Kesimpulan: Dapat disimpulkan bahwa penatalaksanaan utama dari ulkus traumatikus kronis pada rongga mulut adalah dengan menghilangkan faktor penyebab. Ulser yang persisten setelah 2 minggu setelah faktor penyebab dihilangkan, maka diduga suatu keganasan yang perlu pemeriksaan biopsi untuk menegakkan diagnosis akhir.
Sensitivity difference of Streptococcus viridans on 35% Piper betle linn extract and 10% povidone iodine towards recurrent apthous stomatitis Maharani Laillyza Apriasari; Bagus Soebadi; Hening Tuti Hendarti
Dental Journal (Majalah Kedokteran Gigi) Vol. 44 No. 3 (2011): September 2011
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (539.967 KB) | DOI: 10.20473/j.djmkg.v44.i3.p159-163

Abstract

Background: Oral ulceration often becomes the main reason for the patients to see a dentist. Therapy of the oral ulceration is by giving the palliative therapy with topical antiseptic. Nowadays, there are many researches concerning with the traditional medicines as alternative therapy. One of them is Piper betle linn which contains the antiseptic agent. Purpose: This research is aimed to observe the sensitivity difference of Streptococcus viridans on 35% Piper betle linn extract and 10%povidone iodine. Methods: This laboratory research was conducted by the post test only design with random complete design. The research sampel is Streptococcus viridans culture that was scrapped from the ulcer of the recurrent aphthous stomatitis patient, then it was replicated by using the Federer theory. Results: Inhibitory zone of 35% Piper betle linn extract is bigger than 10% povidone iodine. Conclusion: Streptococcus viridans are more sensitive to 35% Piper bittle linn extract than 10% povidone iodine. 35% Piper betle linn extract has more antibacterial effect than 10% povidone iodine.Latar belakang: Ulserasi rongga mulut seringkali menjadi alasan utama bagi pasien untuk memeriksakan diri ke dokter gigi. Terapi ulserasi rongga mulut adalah pemberian terapi paliatif kepada penderita, seperti: pemberian obat topikal yang mengandung antiseptik. Saat ini banyak penelitian dalam pengembangan obat tradisional yang dapat dijadikan sebagai obat alternatif. Salah satu diantaranya adalah daun sirih yang mengandung zat antiseptik. Tujuan: Penelitian ini bertujuan mengetahui perbedaan sensitivitas Streptococcus viridans terhadap ekstrak daun sirih 35% jika dibandingkan dengan povidone iodine 10%. Metode: Penelitian laboratoris yang dilakukan dengan post test only design dengan rancangan acak lengkap. Sampel penelitian adalah kultur Streptococcus viridans yang diambil melalui swab dari hapusan ulser pada pasien yang menderita stomatitis aftosa rekuren, kemudian dilakukan replikasi dengan rumus Federer. Hasil: Zona hambat ekstrak daun sirih 35% lebih besar daripada zona hambat povidone iodine 10%. Kesimpulan: Streptococcus viridans lebih sensitif terhadap ekstrak daun sirih 35%. Ekstrak daun sirih 35% memiliki efek daya antibakteri yang lebih tinggi jika dibandingkan dengan povidone iodine 10%.
Erythema multiforme as the result of taking carbamazepine Maharani Laillyza Apriasari; M. Jusri
Dental Journal (Majalah Kedokteran Gigi) Vol. 43 No. 2 (2010): June 2010
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (428.69 KB) | DOI: 10.20473/j.djmkg.v43.i2.p49-53

Abstract

Background: Erythema multiforme is an acute mucocutaneus disease which is caused by the hypersensitivity reaction. It is characterized by target lesions on the skin or ulcerative oral lesion. Etiology of the disease is unknown, it is currently considered as immunologic disease. The triggering factors is the use of certain type of drugs like antibiotics, anticonvulsant, and NSAID. Most of the dentists do not know about it is mechanism, so a lot of people consider it as a malpractice. Purpose: This paper reported a case of a man, 46 years old which had ulcerative oral mucous, peeled and pain lips after taking carbamazepine drugs. Case: The clinical diagnosis of this case was erythema multiforme because of the hypersensitivity reaction as the result of taking carbamazepine. Case management: The final diagnosis based on anamnesis history of taking systemic drugs and clinical manifestation of erythema multiforme in the oral cavity. The drugs therapy that had been given were antihistamine, oral corticosteroid, gargle liquid contained of topical anesthetic, corticosteroid, and antibiotic. Conclusion: In this case, it can be concluded that erythema multiforme appeared was triggered by taking carbamazepine as the drug of choice for trigeminal neuralgia therapy. These drugs can cause type III hypersensitivity reaction. The final diagnosis based on anamnesis history of taking carbamazepine before lesions erupted and the characterized clinical manifestation.Latar belakang: Erythema multiforme adalah penyakit mukokutaneus akut yang menyerang kulit dan mukosa sebagai akibat dari reaksi hipersensitivitas. Secara karakteristik ditandai oleh lesi target pada kulit atau lesi ulserasi pada mukosa rongga mulut. Etiologi penyakit ini belum jelas, diduga karena adanya reaksi imunologi. Pencetusnya dikarenakan adanya pemakaian obat-obatan tertentu seperti antibiotik, antikonvulsan dan NSAID. Banyak dokter gigi kurang memahami mekanisme timbulnya penyakit ini, sehingga oleh masyarakat dianggap sebagai malpraktek. Tujuan: Tulisan ini melaporkan kasus pasien pria berusia 46 tahun dengan keluhan sariawan dan bibir terkelupas dan sakit setelah sehari meminum obat karbamazepin. Kasus: Diagnosis klinis kasus ini adalah erythema multifome karena reaksi hipersensitivitas terhadap pemakaian obat karbamazepin. Tatalaksana kasus: Diagnosis ditegakkan berdasarkan anamnesis riwayat pemakaian obat sistemik dan manifestasi klinis dari erythema multiforme pada rongga mulut. Pengobatan yang diberikan adalah antihistamin, kortikosteroid oral, obat kumur dengan anastesi topikal, kortikosteroid topikal dan antibiotik topikal. Kesimpulan: Dapat disimpulkan bahwa erythema multiforme yang timbul pada kasus ini dipicu oleh pemakaian obat karbamazepin yang merupakan obat pilihan untuk terapi trigeminal neuralgia. Obat ini menimbulkan efek samping reaksi hipersensitivitas tipe III. Diagnosis ditegakkan berdasarkan anamnesa riwayat pemakaian obat karbamazepin sebelum timbulnya lesi dan pemeriksaan klinis pada pasien.
Immunopathological aspects of oral erythema multiforme Maharani Laillyza Apriasari; Retno Pudji Rahayu
Dental Journal (Majalah Kedokteran Gigi) Vol. 42 No. 4 (2009): December 2009
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (425.331 KB) | DOI: 10.20473/j.djmkg.v42.i4.p159-163

Abstract

Background: Erythema multiforme is an acute disease on the skin and mucous membrane. This lesion can erupt in mucous membranes of the oral cavity. Improper and late treatment may cause Stevens Johnson syndrome which may cause patient mortality, therefore proper and accurate diagnosis are needed. Purpose: The immunopathological aspect of oral erythema multiforme through literature study can help us to find the definite diagnosis and to know the differential diagnosis. review: In immunopathology, minor type of erythema multiforme is vasculitis caused by the immune complex hypersensitivity reaction among antigen antibodies. The mayor type of erythema multiforme may appeared from autoimmune reaction and from untreated minor type of erythema multiforme. Conclusion: Immunopathological approach of erythema multiforme is important beside the clinical manifestation, histology, and the differential diagnosis to find the definitive diagnosis.
Methisoprinol as an immunomodulator for treating infectious mononucleosis Maharani Laillyza Apriasari
Dental Journal (Majalah Kedokteran Gigi) Vol. 49 No. 1 (2016): March 2016
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (555.911 KB) | DOI: 10.20473/j.djmkg.v49.i1.p1-4

Abstract

Background: Infectious mononucleosis (IM) is the self limiting disease that associated with primary Epstein Barr virus (EBV). It is a gamma herpes virus. EBV infection is follows saliva-transfer by kissing or sexual intercourse. The most clinical manifestation in IM consists mainly of the specific sign: pharyngitis, fever, and lymphadenopathy. The main therapy is supportive treatment. Actually the antiviral therapy is required for the host with high response immune. Purpose: The aimed of this study was to report the therapy of IM using methisoprinol. Case: The woman patient, 33 years old, came to hospital by suffering pharyngitis and swolen on left neck. It had been since 3 days ago. Case management: She had come to Puskesmas that were given amoxycillin capsul 500 mg three times a day for three days and paracetamol tablet 500mg three times a day for three days, but she was still ill. Then she came to RSGM Hasan Aman Banjarmasin. She was diagnosed as IM. The instruction were isolation and bed rest for a week. She had to eat sofly and drink water highly. The therapy were amoxycillin capsul 500 mg three times a day for seven days, methisoprinol caplet 500 mg three times a day for seven days, natrium dikofenak tablet 50 mg three times a day for seven days. She was asked to see the dentist next 7 days. In this case, she were not given acyclovir. Conclusion: IM is self limiting disease. IM is the disease with spesific clinical syndrome that associated with primary EBV infection. Depend on the base of clinical experiences, the supportive treatment is adviced for patient of IM. Methisoprinol has both immunomodulator and antiviral properties.
The effect of 25% Mauli banana stem extract gel to increase the epithel thickness of wound healing process in oral mucosa Maharani Laillyza Apriasari; Ariska Endariantari; Ika Kustiyah Oktaviyanti
Dental Journal (Majalah Kedokteran Gigi) Vol. 48 No. 3 (2015): September 2015
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (581.952 KB) | DOI: 10.20473/j.djmkg.v48.i3.p150-153

Abstract

Background: Mauli banana is a special plant of South Borneo that can be used as alternatif medicine for wound healing wound healing. Recent studies showed that Mauli banana stem contained some compound such as flavonoid, saponin, and tannin that had antibacterial and antiinflamation effect, and can accelerate the wound healing. Purpose: This study was aimed to know the effect of 25% Mauli banana extract gel to the epithel thickness of wound healing process in oral mucosa. Method: It was the real experimental with post test only control group design. It used 36 Sprague dawley rats that divided into 3 groups: the negative control group by giving aquadest, the positive control group by giving drug contain Aloe vera, and the treatment group by giving 25% ethanol extract of Mauli banana stem. Biopsy was done on day 3, 5, 7 and the preparat was made to measure the thickness of oral mucosa epithel by Image J software. Result: The result showed that 25% ethanol extract of Mauli banana stem can increased the thickness of oral mucosa epithel on third day (51.26 µm), fifth days (108.49 µm), and seventh day (170.66 µm). The top thickness of mucosa epithel was on the seventh day. Two-ways Anova and Post Hoc LSD (p<0.05) showed the significant different between aquadest and 25% ethanol extract of Mauli banana stem. 25% ethanol extract of Mauli banana stem and drug contains Aloe vera are the aqual of meaningfull. Conclusion: 25%ethanol extract of Mauli banana can increase the epithelial thickness of wound healing procces in oral mucosa.
Co-Authors Adhiya, Geyanina Melda Agung Satria Wardhana Almadina Latanza Amy Nindia Carabelly Anita Fitriani Annisa Vara Nurdianty Aprilyani, Nur Ariska Endariantari Asphia Rahmah Astuti, Nadia Dewi Aulia Azizah Aulia Rahma Annisa Bagus Soebadi Beta Widya Oktiani Beta Widya Oktiani Cane Lukisari, Cane Debby Saputera, Debby Destri Khusnul Khotimah Dewi Nurdiana Dewi Puspitasari Dewi Puspitasari Dewi Rahayu Diah Savitri Ernawati Dita Permatasari Dita Permatasari Dwi Kurniawan, Fajar Kusuma Dwi Setyaningtyas, Dwi Eko Suhartono Eriwati, Yosi Kusuma Erni Marlina Fajriani, Nuril Firdaus, I Wayan Arya Krishnawan Hadi Waskito Hamdani, Riky Hatta, Isnur Hening Tuti Hendarti Husma, Emma Annahal I Wayan Arya K. Firdaus I Wayan Arya Khrisnawan Firdaus I Wayan Arya Krishnawan Firdaus I Wayan Arya Krishnawan Firdaus I Wayan Arya Krisnawan Firdaus Ichrom Nahzi, Muhammad Yanuar Ika Kustiyah Oktaviyanti Khairunnisa Amalia Pratami Koko Komarudin Koko Komarudin Krishnawan Firdaus, I Wayan Arya Kurnia Fatwati Lia Yulia Budiarti M. Jusri M. Ridhotama Wibowo Maria Tanumihardja, Maria Marina Arum Syahadati Mashud, Mustain Melisa Budipramana, Melisa Moh. Ihsan Rifasanto Monica Thiodora Limay Monita Valentine Silalahi Muhammad Ikhlasul Amal Sangadji MUHAMMAD RAYHAN Nadia Dewi Astuti Nafi’ah, Nafi’ah Nor Kamalia Novie Aprianti Novie Aprianti, Novie Nurashfia Nurashfia Nurdiana Dewi Nuril Fajriani Nurrahman, Tri Nurul Ikhsani Umar Pramitha, Selviana Rizky Priyawan Rachmadi Rahmadella, Afifah Renie Kumala Dewi Resha Yusnida Retno Andriati, Retno Retno Pudji Rahayu Ridwan Ichshalul Fuady Rifasanto, Moh. Ihsan Saldy Rizky Saputra Saldy Rizky Saputra, Saldy Rizky Sari, Tiara Intan Permata Serenada Audria Sundah Sherli Diana Tri Putri, Deby Kania Utami, Juliyatin Putri Wenda Fitriati Noor Wenda Fitriati Noor, Wenda Fitriati Yunike Christanti Yusrinie Wasiaturrahmah