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Angular cheilitis and oral pigmentation as early detection of Peutz-Jeghers syndrome Maharani Laillyza Apriasari; Amy Nindia Carabelly
Dental Journal (Majalah Kedokteran Gigi) Vol. 51 No. 1 (2018): March 2018
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (508.174 KB) | DOI: 10.20473/j.djmkg.v51.i1.p29-32

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Background: Peutz-Jeghers syndrome (PJS) is an inherited autosomal dominant disease determined by a mutation localized at 19p13.3 characterized by the occurrence of gastrointestinal hamartomatous polyps in association with mucocutaneous hyperpigmentation. The manifestation of PJS may first be encountered by a dentist during routine examination due to the presence of pigmented spots in the oral cavity. Purpose: To prevent a high risk of PJS, the dentist must establish its oral manifestation through early detection. Case: A 14-year-old male patient attended complaining of a week-long pain at the corners of the lips. An extra-oral exam revealed fissure lesions, redness, white crust and pain. The patient had experienced bleeding in his bowel movements, abdominal pain, nausea and vomiting since childhood. A number of black, painless, macular lesions, some 1-3 mm in diameter, were present on the upper lips, lower lips, fingers and palms. Case management: The patient was referred for a complete blood count check. The results obtained confirmed him to be suffering from severe anemia and he was, therefore, referred to an internist for treatment for PJS. Conclusion: It can be concluded that the early detection of PJS is crucial in order that the patient receives prompt treatment.
Mauli banana stem extract application increased expression of NF-κB in traumatic ulcer healing Maharani Laillyza Apriasari; Retno Pudji Rahayu; Diah Savitri Ernawati
Dental Journal (Majalah Kedokteran Gigi) Vol. 51 No. 2 (2018): June 2018
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v51.i2.p67-70

Abstract

Background: A traumatic ulcer represents one of the most prevalent disorders affecting the oral cavity. Ulceration of the oral cavity potentially results in secondary infection requiring topical medication which involves the use of antiseptics to accelerate wound healing. Previous research has shown that Mauli banana (Musa acuminata) stem extract (MBSE) contains bioactive material from terpenoid saponin present in Ambon bananas. The terpenoid saponin in Ambon banana stems will be captured by a G protein receptor in the macrophages, subsequently producing a protein kinase C that activates nuclear factor kappa beta (NF-κB). This increases both the activity and number of macrophages. Purpose: To analyze the expression of NF-κB (p50) in traumatic ulcers as an effect of MBSE. Methods: A true experimental design with a post-test only control group. It involved 40 male Rattus norvegicus strain rats as traumatic ulcer models divided into four groups: the negative control group administered gel, and the other treatment groups administered 25%, 37.5% and 50% ethanol extracts of MBSE gel respectively. A biopsy was performed on days 3 and 5. The preparation was produced to analyze the expression of NF-κB (p50) by means of immunohistochemistry examination. Results: There was a significant difference (p<0.05) in NF-κB (p50) expression (p=0.005) following MBSE gel administration of 37.5% concentration on day 3 compared to day 5. Conclusion: It can be concluded that MBSE gel topical application can increase expression of NF-κB (p50) in traumatic ulcer healing.
The different symptoms determining management of hand foot and mouth disease and primary varicella zoster infection Maharani Laillyza Apriasari
Dental Journal (Majalah Kedokteran Gigi) Vol. 52 No. 1 (2019): March 2019
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (673.04 KB) | DOI: 10.20473/j.djmkg.v52.i1.p32-35

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Background: Hand, foot and mouth disease (HFMD) is a medical condition endemic among children in South-East Asia, including Indonesia and, more specifically, Banjarmasin – the capital of South Sulawesi. The disease is mediated by Enterovirus 71 and Coxsackievirus 16 which attack the oral cavity, hands, feet, buttocks and genital areas. One differential diagnosis of this disease is Primary Varicella Zoster infection. Both diseases have similar clinical symptoms but different etiologies which can precipitate errors in the administration of therapy Purpose: To elucidate the distinction between HFMD and Primary varicella zoster infection. Case: An 8 year-old male sought treatment complaining of ulcers on the upper maxillary gingiva followed by the appearance of itchy and painful lesions affecting the nose, upper lip, hands and feet. The patient’s mother reported his history of 39oC fever followed by the development of red spots and ulcers on the face, hands and feet which caused itching. Clinically, it is similar to Primary varicella zoster infection which can affect any part of the body. The patient only used an immunomodulator once a day and was actively seeking available healthcare. Case management: Extraoral examination confirmed the presence of multiple erythematous vesicles and ulcers, 2 mm in diameter, which caused a sensation of itching around the nose and upper lip region. Multiple painful and itchy red macules and vesicles, 3-6 mm in diameter, appeared not only on the patient’s palms, back of the hands and feet. Intraoral examination of the right maxillary gingiva revealed multiple painful ulcers, 1-2 mm in diameter and yellowish in appearance, surrounded by erythema. The results of history-taking implied that no lesions appeared on other parts of the body. Conclusion: While these conditions share similar clinical manifestations, their contrasting etiologies require different treatments. The ultimate diagnosis can be determined clinically by the dentist, thereby preventing errors in the administration of therapy.
The management of herpes labialis, oral thrush and angular cheilitis in cases of oral diabetes Maharani Laillyza Apriasari
Dental Journal (Majalah Kedokteran Gigi) Vol. 52 No. 2 (2019): June 2019
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (511.296 KB) | DOI: 10.20473/j.djmkg.v52.i2.p76-80

Abstract

Background: As reported in several studies, prolonged or uncontrolled cases of diabetes mellitus (DM) may induce a more extreme inflammatory response. Mucosal lesions can be observed in patients who present this systemic condition. Purpose: The purpose of this study was to elaborate the management of herpes labialis, oral thrush and angular cheilitis as oral manifestations of diabetes. Case: A 49-year-old male complained of having experienced painful lip ulceration for the preceding seven days. The anamnesis of the patient revealed that, prior to lip ulceration, he had experienced high fever and malaise in addition to frequent urination at night and a tingling sensation in the toes and fingertips on waking. Case management: The patient was referred to undergo blood count, fasting blood glucose and oral glucose tolerance tests. The blood test result confirmed the patient to be suffering from DM and anemia. The immunocompromised condition of the patient prompted the occurrence of herpes labialis, oral thrush and angular cheilitis. Conclusion: Multidisciplinary treatment for herpes labialis resulting in oral candidiasis in DM patients is indispensable. Concurrent infection with HSV and candidiasis necessitates a more prolonged healing process. Consequently, it is a essential to treat the hyperglycemia which induces an immunocompromised state in diabetic patients.
Aktivitas Antifungi Ekstrak Etanol dan Metanol Batang Pisang Mauli 100% Maharani Laillyza Apriasari
STOMATOGNATIC - Jurnal Kedokteran Gigi Vol 12 No 1 (2015)
Publisher : Fakultas Kedokteran Gigi Universitas Jember

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Abstract

Background: North Hulu Sungai Banjarmasin people are using banana stem mauli to accelerate wound healing in the skin. Mauli banana stem extract contains antimicrobial and antioxidant effects. Need the development of traditional plants that can be used as a topical antiseptic drug in the oral cavity. Purpose: to determine the anti fungal affectivity of methanolextract of 100% mauli banana stem compared with the ethanol extract of 100% mauli banana stem. Methods and materials: pure laboratory experimental research with the completely randomized design using 3 treatments with 9 replications. Making 100% banana mauli stem extract by maceration method using the solution of ethanol and methanol. The sample was a pure culture of Candida albicans. Saboroud agar petridish were contained Candida albicans that have given filter paper soaked for 3 hours with100% methanol extract of mauli banana stem, 100% ethanol extract of mauli banana stem, and 0,2% Clorhexidine gluconate. Inhibition zone diameter of three treatments was compared after doing incubation for 1 day. It using the diffusion method. Results: Kruskal Wallis test of the three treatment resulted p value=0.00(p <0.05) that H0 was rejected, so it could be concluded that there were significant differences between the three treatments. Mann Whitney test resulted that the treatment of 100% ethanol was compared with100% methanol resulted p = 0.00 (p <0.05).There was a significant difference between the treatment of 100% ethanol and 100% methanol to the growthness of Candida albicans. Conclusion: The results of the study it appears that the banana stem mauli have antimicrobial activity. Methanol extract of banana stem mauli has a total flavonoids was higher than the ethanol extract of banana stem mauli. This makes methanol extracts had higher antifungal activity than the ethanol extract.
PREVALENCE OF ORAL DISEASES AT ULIN HOSPITAL BANJARMASIN IN 2017-2019 Maharani Laillyza Apriasari; Serenada Audria Sundah; Riky Hamdani
ODONTO : Dental Journal Vol 9, No 1 (2022): July 2022
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.9.1.62-72

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Background: Oral disease is a condition that causes lesions in the oral cavity, which can be influenced by age, gender, and level of education. Oral health is still becoming a problem in society that needs attention. According to basic health research 2018, the prevalence of oral disease in Indonesia remains considerably high reaching 57.6%. Oral diseases have practically been observed in Banjarmasin, yet no research has presented the prevalence of oral diseases in Ulin General Hospital, Banjarmasin. The purpose of this study was to determine the prevalence of oral disease in Ulin Hospital, Banjarmasin in 2017-2019Method: This research is a descriptive study using secondary data from medical record. Sampling method was carried out by total population sampling of oral disease patients who were treated at Oral and Dental Clinic, Ulin Hospital in 2017-2019Result: It showed that out of 102 oral disease patients, there were 78 patients suffering from recurrent aphthous stomatitis (76.5%), 8 patients from oral candidiasis (7.8%), 7 patients from oral squamous cell carcinoma (6.9%), 4 patients from oral submucous fibrosis (3.9%), 3 patients from burning mouth syndrome (2.9%), and 2 patients from allergic stomatitis (2%). Oral diseases were mostly found in over-45-years age group (54.9%), with the highest gender proportion is female reaching of 64.7%. Approximately 31.4% patients had completed high school education. Medical management was given to 60,8% patients with oral diseases.Conclusion: Recurrent aphthous stomatitis was the most common oral disease in Ulin Hospital, in 2017-2019, followed by oral candidiasis and oral squamous cell carcinoma.
ANTIBACTERIAL EFFECT OF KELAKAI LEAF EXTRACT (STENOCHLAENA PALUSTRIS (BURM) BEDD.) FOR INHIBITING ENTEROCOCCUS FAECALIS I Wayan Arya Krishnawan Firdaus; Nurdiana Dewi; Ridwan Ichshalul Fuady; Maharani Laillyza Apriasari
ODONTO : Dental Journal Vol 9, No 1 (2022): July 2022
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.9.1.110-118

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Background: Root canal treatment is a stage of treating pulp infection by removing the necrotic tissue and eliminating microorganisms. Inadequate sterilization cause persistent root canal bacteria, including Enterococcus faecalis. The irrigation solution that has become the gold standard in root canal treatment is Sodium hypochlorite but it has some weaknesses. Kelakai leaf extract can be an alternative root canal irrigation because it has minimal side effects and antibacterial compounds such as flavonoid, saponin, alkaloid, and tannin.Methods: This research was a true experimental laboratory with posttest only and control group design. The research using 5 treatment groups with 3 replications, so that total sample was 15 samples. Group 1-4 were kelakai leaf extract concentrations of 25%, 50%, 75%, 100% and group 5 was Sodium hypochlorite 2,5%. The parameter measured was the diameter of the inhibition zone (mm) formed on MHA.Results: One Way Anova and Post Hoc LSD test results showed a significant difference between each treatment group of kelakai leaf extract compared with Sodium hypochlorite 2,5%. Kelakai leaf extract 25%, 50%, 75%, 100% concentrations, and Sodium hypochlorite 2,5% had an average inhibition zone diameter which were 9.47 mm, 14.64 mm, 17.91 mm, 21.24 mm, and 23.27 mm.Conclusion: Kelakai leaf extract concentrations of 25%, 50%, 75%, and 100% had inhibitory activity against Enterococcus faecalis but had not been equivalent to Sodium hypochlorite 2,5%.
Pelatihan Dasar Kader Posyandu Fakultas Kedokteran Gigi Dalam Upaya Penanggulangan Gigi Berlubang Renie Kumala Dewi; Maharani Laillyza Apriasari; I Wayan Arya Krisnawan Firdaus
Jurnal Pengabdian ILUNG (Inovasi Lahan Basah Unggul) Vol 2, No 2 (2022)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ilung.v2i2.6170

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Kesehatan mulut dan gigi merupakan suatu hal yang penting, maka usaha perawatan kesehatan mulut dan gigi perlu dibina sejak dini. Masyarakat Desa Pulau Sugara sebagian besar masih menggunakan air sungai dalam kehidupan sehari-hari sehingga perlu dilakukan penyuluhan terhadap penggunan air sungai terhadap Kesehatan mulut dan gigi anak. Kader posyandu adalah anggota masyarakat yang dipilih untuk menangani masalah-masalah kesehatan termasuk kesehatan gigi dan mulut. Metode pelatihan dilakukan bersama KAPORAGI (Kader Posyandu Fakultas Kedokteran Gigi) dipilih dan dilatih oleh Tim/peserta kegiatan PKM FKG ULM untuk dapat memberikan penyuluhan kesehatan mulut dan gigi pada saat melakukan posyandu serta memeriksa rongga mulut anak apakah terdapat lubang pada giginya kemudian dicatat dalam odontogram kedokteran gigi seperti pada acuan buku pedoman kesehatan mulut dan gigi bagi KAPORAGI yang telah dibuat oleh Tim/peserta kegiatan PKM FKG ULM, sehingga segera dapat dijadwalkan untuk dirujuk ke Puskesmas terdekat untuk melakukan perawatan gigi dan mulut pada anak tersebut. Kegiatan pelatihan ini secara keseluruhan dapat dikatakan baik dilihat dari ketercapaian tujuan pelatihan, antusiasme peserta pelatihan, dan pengetahuan para orang tua yang masih sedang (64,7%) mengenai Kesehatan mulut dan gigi yang didapatkan melalui pengisian kuesioner pada waktu pelaksanaan kegiatan sehingga perlu peran KAPORAGI memberikan pengetahuan kesehatan mulut dan gigi anak yang tinggal di pinggiran sungai dan menjaring karies gigi pada anak usia dini sehingga segera tertangani dan tidak terjadi kerusakan yang lebih parah pada gigi anak.
Oxidative Stress on Buccal Mucosa Wound in Rats and Rule of Topical Application of Ethanolic Extracts of Mauli Banana (Musa acuminata) Stem Wenda Fitriati Noor; Novie Aprianti; Saldy Rizky Saputra; Maharani Laillyza Apriasari; Eko Suhartono
Journal of Tropical Life Science Vol. 5 No. 2 (2015)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.05.02.05

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The present study was undertaken to evaluate the effect of a topical application of ethanolic extracts of Mauli banana stem on buccal mucosa wounds in rats (Rattus novergicus). Three sets of experiments with 3 groups male rats each consisted of 9 animals were used for studying wound oxidative stress status. Group 1 (P0) as the negative control was left to heal spontaneously; group 2 (P1) as the postive control were treated with alocair topically; and group 3 (P2) as treatment group were treated with ethanloic extracts of Mauli banana stem topically, respectively, 24h after wound creation for 3 days. The oxidative stress status was evaluated by monitoring the SOD, CAT activity, MDA and CC levels. The effect of ethanolic extracts of Mauli banana stem on oxidative stress status revealed significant increased in SOD activity, decreased in MDA levels, and no significant change both in CAT activity and CC levels compared to negative control. These results showed that The ethanolic extracts of Mauli banana stem might affect the oxidative stress status during wound healing process. Key Word : Antioxidant, Free Radicals, Mauli banana, Oxidative Stress, Wound Healing.
The social resilience of fishermen to oral diseases during the covid-19 pandemic in puger jember east java Koko Komarudin; Mustain Mashud; Retno Andriati; Maharani Laillyza Apriasari
Odonto : Dental Journal Vol 9, No 2 (2022): December 2022
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.9.2.279-289

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Background: Puger fishermen are able to survive and develop (resilience) in carrying out their activities in the form of natural disturbances and various diseases, especially during the COVID-19 pandemic. Oral diseases are the lowest of the seven diseases recorded at the Puger Health Center. This disease can make patients exposed to COVID-19 worse, but the Puger area is included in the green zone. The Purpose of this study is to analyze the effect of knowledge, behavior and health services to the social resilience ability of Puger fishermen.Method: It used a quantitative approach with the method of structural equation modelling (SEM). Confirmatory factor analysis tests and path analysis were conducted to analyze the effect among variables according to the research purpose. Questionnaires were distributed to fishermen who were sampled as respondents. Respondents amounted to 111 people. It used is simple random sampling.Result: The knowledge has a positive effect, but it is not significant to social resilience with a significance level (β= 0.001 p: 0.314>0.05), behavior has a positive effect, but it is not significant to social resiliance with a significance level (β= 0.005 p: 0.649>0.05) and Health service has a positive effect, but it is not significant to social resilience with a significance level (β= 0.003 p: 0.218>0.05).Conclusion: Puger Fishermen has social resilience ability to oral diseases underpinned by knowledge, behavior as well as health service. These variables have a positive correlation with resilience. Yet the level is not quite significant.
Co-Authors Adhiya, Geyanina Melda Agung Satria Wardhana Almadina Latanza Amy Nindia Carabelly Anita Fitriani Annisa Vara Nurdianty Aprilyani, Nur Ariska Endariantari Asphia Rahmah Astuti, Nadia Dewi Aulia Azizah Aulia Rahma Annisa Bagus Soebadi Beta Widya Oktiani Beta Widya Oktiani Cane Lukisari, Cane Debby Saputera, Debby Destri Khusnul Khotimah Dewi Nurdiana Dewi Puspitasari Dewi Puspitasari Dewi Rahayu Diah Savitri Ernawati Dita Permatasari Dita Permatasari Dwi Kurniawan, Fajar Kusuma Dwi Setyaningtyas, Dwi Eko Suhartono Eriwati, Yosi Kusuma Erni Marlina Fajriani, Nuril Firdaus, I Wayan Arya Krishnawan Hadi Waskito Hamdani, Riky Hatta, Isnur Hening Tuti Hendarti Husma, Emma Annahal I Wayan Arya K. Firdaus I Wayan Arya Khrisnawan Firdaus I Wayan Arya Krishnawan Firdaus I Wayan Arya Krishnawan Firdaus I Wayan Arya Krisnawan Firdaus Ichrom Nahzi, Muhammad Yanuar Ika Kustiyah Oktaviyanti Khairunnisa Amalia Pratami Koko Komarudin Koko Komarudin Krishnawan Firdaus, I Wayan Arya Kurnia Fatwati Lia Yulia Budiarti M. Jusri M. Ridhotama Wibowo Maria Tanumihardja, Maria Marina Arum Syahadati Mashud, Mustain Melisa Budipramana, Melisa Moh. Ihsan Rifasanto Monica Thiodora Limay Monita Valentine Silalahi Muhammad Ikhlasul Amal Sangadji MUHAMMAD RAYHAN Nadia Dewi Astuti Nafi’ah, Nafi’ah Nor Kamalia Novie Aprianti Novie Aprianti, Novie Nurashfia Nurashfia Nurdiana Dewi Nuril Fajriani Nurrahman, Tri Nurul Ikhsani Umar Pramitha, Selviana Rizky Priyawan Rachmadi Rahmadella, Afifah Renie Kumala Dewi Resha Yusnida Retno Andriati, Retno Retno Pudji Rahayu Ridwan Ichshalul Fuady Rifasanto, Moh. Ihsan Saldy Rizky Saputra Saldy Rizky Saputra, Saldy Rizky Sari, Tiara Intan Permata Serenada Audria Sundah Sherli Diana Tri Putri, Deby Kania Utami, Juliyatin Putri Wenda Fitriati Noor Wenda Fitriati Noor, Wenda Fitriati Yunike Christanti Yusrinie Wasiaturrahmah