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All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Jurnal Berkala Epidemiologi STOMATOGNATIC- Jurnal Kedokteran Gigi ODONTO Dental Journal Dentino: Jurnal Kedokteran Gigi Berkala Kedokteran Dental Journal (Majalah Kedokteran Gigi) Padjadjaran Journal of Dentistry Dentin Jurnal Insan Farmasi Indonesia Jurnal Pengabdian Ilung (Inovasi Lahan Basah Unggul) Denta: Jurnal Kedokteran Gigi Odonto dental journal

Maharani Laillyza Apriasari

Departement Of Oral Medicine, Faculty Of Dentistry, Lambung Mangkurat University

Author-ID : 485202

Agriculture, Biological Sciences & Forestry Arts Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Energy Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Mauli banana stem extract application increased expression of NF-κB in traumatic ulcer healing Maharani Laillyza Apriasari; Retno Pudji Rahayu; Diah Savitri Ernawati
Dental Journal (Majalah Kedokteran Gigi) Vol. 51 No. 2 (2018): June 2018
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v51.i2.p67-70

Background: A traumatic ulcer represents one of the most prevalent disorders affecting the oral cavity. Ulceration of the oral cavity potentially results in secondary infection requiring topical medication which involves the use of antiseptics to accelerate wound healing. Previous research has shown that Mauli banana (Musa acuminata) stem extract (MBSE) contains bioactive material from terpenoid saponin present in Ambon bananas. The terpenoid saponin in Ambon banana stems will be captured by a G protein receptor in the macrophages, subsequently producing a protein kinase C that activates nuclear factor kappa beta (NF-κB). This increases both the activity and number of macrophages. Purpose: To analyze the expression of NF-κB (p50) in traumatic ulcers as an effect of MBSE. Methods: A true experimental design with a post-test only control group. It involved 40 male Rattus norvegicus strain rats as traumatic ulcer models divided into four groups: the negative control group administered gel, and the other treatment groups administered 25%, 37.5% and 50% ethanol extracts of MBSE gel respectively. A biopsy was performed on days 3 and 5. The preparation was produced to analyze the expression of NF-κB (p50) by means of immunohistochemistry examination. Results: There was a significant difference (p<0.05) in NF-κB (p50) expression (p=0.005) following MBSE gel administration of 37.5% concentration on day 3 compared to day 5. Conclusion: It can be concluded that MBSE gel topical application can increase expression of NF-κB (p50) in traumatic ulcer healing.

The different symptoms determining management of hand foot and mouth disease and primary varicella zoster infection Maharani Laillyza Apriasari
Dental Journal (Majalah Kedokteran Gigi) Vol. 52 No. 1 (2019): March 2019
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Background: Hand, foot and mouth disease (HFMD) is a medical condition endemic among children in South-East Asia, including Indonesia and, more specifically, Banjarmasin – the capital of South Sulawesi. The disease is mediated by Enterovirus 71 and Coxsackievirus 16 which attack the oral cavity, hands, feet, buttocks and genital areas. One differential diagnosis of this disease is Primary Varicella Zoster infection. Both diseases have similar clinical symptoms but different etiologies which can precipitate errors in the administration of therapy Purpose: To elucidate the distinction between HFMD and Primary varicella zoster infection. Case: An 8 year-old male sought treatment complaining of ulcers on the upper maxillary gingiva followed by the appearance of itchy and painful lesions affecting the nose, upper lip, hands and feet. The patient’s mother reported his history of 39oC fever followed by the development of red spots and ulcers on the face, hands and feet which caused itching. Clinically, it is similar to Primary varicella zoster infection which can affect any part of the body. The patient only used an immunomodulator once a day and was actively seeking available healthcare. Case management: Extraoral examination confirmed the presence of multiple erythematous vesicles and ulcers, 2 mm in diameter, which caused a sensation of itching around the nose and upper lip region. Multiple painful and itchy red macules and vesicles, 3-6 mm in diameter, appeared not only on the patient’s palms, back of the hands and feet. Intraoral examination of the right maxillary gingiva revealed multiple painful ulcers, 1-2 mm in diameter and yellowish in appearance, surrounded by erythema. The results of history-taking implied that no lesions appeared on other parts of the body. Conclusion: While these conditions share similar clinical manifestations, their contrasting etiologies require different treatments. The ultimate diagnosis can be determined clinically by the dentist, thereby preventing errors in the administration of therapy.

The management of herpes labialis, oral thrush and angular cheilitis in cases of oral diabetes Maharani Laillyza Apriasari
Dental Journal (Majalah Kedokteran Gigi) Vol. 52 No. 2 (2019): June 2019
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Background: As reported in several studies, prolonged or uncontrolled cases of diabetes mellitus (DM) may induce a more extreme inflammatory response. Mucosal lesions can be observed in patients who present this systemic condition. Purpose: The purpose of this study was to elaborate the management of herpes labialis, oral thrush and angular cheilitis as oral manifestations of diabetes. Case: A 49-year-old male complained of having experienced painful lip ulceration for the preceding seven days. The anamnesis of the patient revealed that, prior to lip ulceration, he had experienced high fever and malaise in addition to frequent urination at night and a tingling sensation in the toes and fingertips on waking. Case management: The patient was referred to undergo blood count, fasting blood glucose and oral glucose tolerance tests. The blood test result confirmed the patient to be suffering from DM and anemia. The immunocompromised condition of the patient prompted the occurrence of herpes labialis, oral thrush and angular cheilitis. Conclusion: Multidisciplinary treatment for herpes labialis resulting in oral candidiasis in DM patients is indispensable. Concurrent infection with HSV and candidiasis necessitates a more prolonged healing process. Consequently, it is a essential to treat the hyperglycemia which induces an immunocompromised state in diabetic patients.

Aktivitas Antifungi Ekstrak Etanol dan Metanol Batang Pisang Mauli 100% Maharani Laillyza Apriasari
STOMATOGNATIC - Jurnal Kedokteran Gigi Vol 12 No 1 (2015)
Publisher : Fakultas Kedokteran Gigi Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Background: North Hulu Sungai Banjarmasin people are using banana stem mauli to accelerate wound healing in the skin. Mauli banana stem extract contains antimicrobial and antioxidant effects. Need the development of traditional plants that can be used as a topical antiseptic drug in the oral cavity. Purpose: to determine the anti fungal affectivity of methanolextract of 100% mauli banana stem compared with the ethanol extract of 100% mauli banana stem. Methods and materials: pure laboratory experimental research with the completely randomized design using 3 treatments with 9 replications. Making 100% banana mauli stem extract by maceration method using the solution of ethanol and methanol. The sample was a pure culture of Candida albicans. Saboroud agar petridish were contained Candida albicans that have given filter paper soaked for 3 hours with100% methanol extract of mauli banana stem, 100% ethanol extract of mauli banana stem, and 0,2% Clorhexidine gluconate. Inhibition zone diameter of three treatments was compared after doing incubation for 1 day. It using the diffusion method. Results: Kruskal Wallis test of the three treatment resulted p value=0.00(p <0.05) that H0 was rejected, so it could be concluded that there were significant differences between the three treatments. Mann Whitney test resulted that the treatment of 100% ethanol was compared with100% methanol resulted p = 0.00 (p <0.05).There was a significant difference between the treatment of 100% ethanol and 100% methanol to the growthness of Candida albicans. Conclusion: The results of the study it appears that the banana stem mauli have antimicrobial activity. Methanol extract of banana stem mauli has a total flavonoids was higher than the ethanol extract of banana stem mauli. This makes methanol extracts had higher antifungal activity than the ethanol extract.

Pelatihan Dasar Kader Posyandu Fakultas Kedokteran Gigi Dalam Upaya Penanggulangan Gigi Berlubang Renie Kumala Dewi; Maharani Laillyza Apriasari; I Wayan Arya Krisnawan Firdaus
Jurnal Pengabdian ILUNG (Inovasi Lahan Basah Unggul) Vol 2, No 2 (2022)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ilung.v2i2.6170

Kesehatan mulut dan gigi merupakan suatu hal yang penting, maka usaha perawatan kesehatan mulut dan gigi perlu dibina sejak dini. Masyarakat Desa Pulau Sugara sebagian besar masih menggunakan air sungai dalam kehidupan sehari-hari sehingga perlu dilakukan penyuluhan terhadap penggunan air sungai terhadap Kesehatan mulut dan gigi anak. Kader posyandu adalah anggota masyarakat yang dipilih untuk menangani masalah-masalah kesehatan termasuk kesehatan gigi dan mulut. Metode pelatihan dilakukan bersama KAPORAGI (Kader Posyandu Fakultas Kedokteran Gigi) dipilih dan dilatih oleh Tim/peserta kegiatan PKM FKG ULM untuk dapat memberikan penyuluhan kesehatan mulut dan gigi pada saat melakukan posyandu serta memeriksa rongga mulut anak apakah terdapat lubang pada giginya kemudian dicatat dalam odontogram kedokteran gigi seperti pada acuan buku pedoman kesehatan mulut dan gigi bagi KAPORAGI yang telah dibuat oleh Tim/peserta kegiatan PKM FKG ULM, sehingga segera dapat dijadwalkan untuk dirujuk ke Puskesmas terdekat untuk melakukan perawatan gigi dan mulut pada anak tersebut. Kegiatan pelatihan ini secara keseluruhan dapat dikatakan baik dilihat dari ketercapaian tujuan pelatihan, antusiasme peserta pelatihan, dan pengetahuan para orang tua yang masih sedang (64,7%) mengenai Kesehatan mulut dan gigi yang didapatkan melalui pengisian kuesioner pada waktu pelaksanaan kegiatan sehingga perlu peran KAPORAGI memberikan pengetahuan kesehatan mulut dan gigi anak yang tinggal di pinggiran sungai dan menjaring karies gigi pada anak usia dini sehingga segera tertangani dan tidak terjadi kerusakan yang lebih parah pada gigi anak.

Oxidative Stress on Buccal Mucosa Wound in Rats and Rule of Topical Application of Ethanolic Extracts of Mauli Banana (Musa acuminata) Stem Wenda Fitriati Noor; Novie Aprianti; Saldy Rizky Saputra; Maharani Laillyza Apriasari; Eko Suhartono
Journal of Tropical Life Science Vol. 5 No. 2 (2015)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.05.02.05

The present study was undertaken to evaluate the effect of a topical application of ethanolic extracts of Mauli banana stem on buccal mucosa wounds in rats (Rattus novergicus). Three sets of experiments with 3 groups male rats each consisted of 9 animals were used for studying wound oxidative stress status. Group 1 (P0) as the negative control was left to heal spontaneously; group 2 (P1) as the postive control were treated with alocair topically; and group 3 (P2) as treatment group were treated with ethanloic extracts of Mauli banana stem topically, respectively, 24h after wound creation for 3 days. The oxidative stress status was evaluated by monitoring the SOD, CAT activity, MDA and CC levels. The effect of ethanolic extracts of Mauli banana stem on oxidative stress status revealed significant increased in SOD activity, decreased in MDA levels, and no significant change both in CAT activity and CC levels compared to negative control. These results showed that The ethanolic extracts of Mauli banana stem might affect the oxidative stress status during wound healing process. Key Word : Antioxidant, Free Radicals, Mauli banana, Oxidative Stress, Wound Healing.

Acute Toxicity Test of Toman Fish Extract on Erythrocyte Number and Hemoglobin Level in Normal and Diabetic Wistar Rat Model Amy Nindia Carabelly; Beta Widya Oktiani; Nurashfia Nurashfia; Maharani Laillyza Apriasari; Dewi Puspitasari
Berkala Kedokteran Vol 19, No 1 (2023)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v19i1.15703

Abstract: Patients with diabetes mellitus (DM) may experience vascular impairment, wounds that emerged from dental practice require special attention in people who suffer from DM. Toman fish has the potential as an alternative medicine to accelerate the healing process in normal and diabetic wound. Erythrocyte and hemoglobin are two components of blood profile which can be used as the parameter to identify the effect of material toxicity. This study aims to test the acute toxicity of Toman fish extract at 16 mL/Kg BW dosage on the number of erythrocyte and the level of hemoglobin in normal and diabetic Wistar rat model after 14 days treatment. This is a true experimental study with post-test only and control group design. Samples were comprised of 21 male Wistar rats allocated to three different groups; normal rats given Toman fish extract (A), diabetic rats given Toman fish extract (B), and diabetic rats given BR2 feed only (C). The results showed that in group A, the number of erythrocytes was 8.67x106/mm3 and the level of hemoglobin was 17.30 g/dL. In group B, the number of erythrocytes was 7.39x106/mm3 and the level of hemoglobin was 16.32 g/dL. In group C, the erythrocyte number was 4.88x106/ mm3 and the hemoglobin level was 11.54 g/dL. It can be concluded that Toman fish extract at the dosage of 16 mL/Kg BW after 14 days administration is not toxic which was indicated by erythrocyte number and hemoglobin level in the blood of normal and diabetic Wistar rats models.

QUANTITATIVE PHYTOCHEMICAL TEST OF METHANOL EXTRACT OF TABAT BARITO LEAVES (Ficus deltoidea Jack.) I Wayan Arya Krishnawan Firdaus; Asphia Rahmah; Maharani Laillyza Apriasari; Yusrinie Wasiaturrahmah
Dentino : Jurnal Kedokteran Gigi Vol 8, No 1 (2023)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v8i1.16085

ABSTRACTBackground: Tabat barito is a medicinal plant that has long been used by various ethnic groups in Indonesia, especially on the islands of Sumatra and Kalimantan. The people of Kalimantan use tabat barito as a traditional medicine for women who have just given birth, enhance blood circulation and get energy. Tabat barito leaves contain alkaloids, flavonoids, steroids, and phenolic compounds. Because of its use only based on the results of community trials and passed down orally, scientific research is needed for the chemical content or compounds contained therein. It aims to determine the bioactive profile of plants that play a role in therapy and their use can be accounted for. Purpose: To analyze the quantitative phytochemical test results of the methanol extract of tabat barito leaves (Ficus deltoidea Jack.) 100% concentration. Methods: Non-experimental research with quantitative laboratory examination to determine sample content. Results: The results showed that the total alkaloids content 154.31 mg/ml, flavonoids 62.917 mg/ml, steroids 49.036, and phenolic 99.689 mg/ml. Conclusion: The methanol extract of tabat barito leaves showed the content of alkaloid compounds at 154.31 mg/ml, flavonoids at 62.917 mg/ml, steroids at 49.036 mg/ml, and phenolics at 99.689 mg/ml. The compound with the highest total content was alkaloid at 154.31 mg/ml and the compound with the lowest total content was steroid at 49.036 mg/ml. Keywords: gravimetric, tabat barito leaves, uv-vis spectrophotometry, quantitative phytochemical test

ANTIBACTERIAL ACTIVITY OF MIXED MAULI BANANA STEM AND BASIL LEAVES AGAINST Staphylococcus aureus Melisa Budipramana; Yunike Christanti; Maharani Laillyza Apriasari; Juliyatin Putri Utami
Dentino : Jurnal Kedokteran Gigi Vol 8, No 1 (2023)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v8i1.16069

ABSTRACTBackground: Mauli banana is a typical plant in South Kalimantan which contains tannins (67.59%), saponins (14.49%), alkaloids (0.34%), and flavonoids (0.25%) as natural antiseptics inhibiting the growth of Streptococcus mutans. Basil is plant that contain eugenol (70%), flavonoids (4.75%), tannins (4.6%), and alkaloids (1%) as natural antiseptics inhibiting the growth of Candida albicans. This study was to examine the antibacterial activity of a mixture of banana mauli stem stems and basil leaves against Staphylococcus aureus. Purpose: to analyze the antibacterial activity against Staphylococcus aureus in the mixture of banana mauli stems and basil leaves extracts. Method: true experiment using pretest and posttest with control group design with 11 treatments consisting of 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90%, 100%, and aquadest. Antibacterial activity test was conducted using dilution method. Determination of Minimum Inhibitory Concentration (MIC) was determined by contrasting the absorbance value before and after incubation. Minimum Bactericidal Concentration (MBC) was obtained by testing the concentration with negative absorbance value on MSA media incubated for 24 hours. Results: The results of this study indicated that the concentration of 40%, 50%, 60%, 70%, 80%, 90%, and 100% could inhibit the growth of Staphylococcus aureus but these concentrations had yet been able to kill Staphylococcus aureus. Conclusion: The MIC of mauli banana and basil leaves extract combination against S aureus presentts at 40% concentration yet MBC cannot be obtained.Keywords : Antibacterial activity, Basil leaf, Dilution method, Mauli banana stem, Staphylococcus aureus

THE RELATIONSHIP BETWEEN STRESS AND RECURRENT APHTHOUS STOMATITIS AMONG STUDENTS OF THE DENTISTRY FACULTY OF LAMBUNG MANGKURAT UNIVERSITY: Hubungan Stres Terhadap Kejadian Stomatitis Aftosa Rekuren pada Mahasiswa Fakultas Kedokteran Gigi Universitas Lambung Mangkurat Riky Hamdani; Anita Fitriani; Maharani Laillyza Apriasari
Jurnal Berkala Epidemiologi Vol. 11 No. 2 (2023): Jurnal Berkala Epidemiologi (Periodic Epidemiology Journal)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbe.V11I22023.135-141

Background: Recurrent aphthous stomatitis (RAS) is a yellowish-white ulcer-shaped lesion in the oral mucosa. The prevalence of RAS is estimated to be 20% of the world population. Based on Basic Health Search Indonesia in 2018, the prevalence of RAS was 8% of all oral health problems in Indonesia. Stress is one of the risk factors for recurrent aphthous stomatitis. Someone who is stressed will experience a decrease in the immune system, resulting in tissue destruction in the oral cavity. Purpose: To analyze the relationship between stress and RAS in Faculty of Dentistry, Lambung Mangkurat University students. Methods: This is analytical observational research with a cross-sectional study design. The study used a simple random sampling technique with a total sample of 57 co-assistants of the Dentistry at Lambung Mangkurat University. RAS was examined using a questionnaire, and the stress level was measured using the Perceived Stress Scale (PSS) questionnaire. The results of the study were analyzed using the chi-square test. Results: The result shows that the stress level suffered by the respondents is mainly in the moderate category, with a percentage of 44%. In comparison, the incident of RAS with positive results is mainly experienced by respondents with a percentage of 70.18%. The analysis using the chi-square test showed a significant relationship between stress and SAR with a significance value of 0.01 (p <0.05). Conclusion: The higher the stress level experienced will increase the risk of developing SAR.

Co-Authors Adhiya, Geyanina Melda Agung Satria Wardhana Almadina Latanza Amy Nindia Carabelly Anita Fitriani Annisa Vara Nurdianty Aprilyani, Nur Ariska Endariantari Asphia Rahmah Astuti, Nadia Dewi Aulia Azizah Aulia Rahma Annisa Bagus Soebadi Beta Widya Oktiani Beta Widya Oktiani Cane Lukisari, Cane Debby Saputera, Debby Destri Khusnul Khotimah Dewi Nurdiana Dewi Puspitasari Dewi Puspitasari Dewi Rahayu Diah Savitri Ernawati Dita Permatasari Dita Permatasari Dwi Kurniawan, Fajar Kusuma Dwi Setyaningtyas, Dwi Eko Suhartono Eriwati, Yosi Kusuma Erni Marlina Fajriani, Nuril Firdaus, I Wayan Arya Krishnawan Fuady, Ridwan Ichshalul Hadi Waskito Hamdani, Riky Hatta, Isnur Hening Tuti Hendarti Husma, Emma Annahal I Wayan Arya K. Firdaus I Wayan Arya Khrisnawan Firdaus I Wayan Arya Krishnawan Firdaus I Wayan Arya Krisnawan Firdaus Ichrom Nahzi, Muhammad Yanuar Ika Kustiyah Oktaviyanti Khairunnisa Amalia Pratami Komarudin, Koko Krishnawan Firdaus, I Wayan Arya Kurnia Fatwati Lia Yulia Budiarti M. Jusri M. Ridhotama Wibowo Maria Tanumihardja, Maria Marina Arum Syahadati Mashud, Mustain Melisa Budipramana, Melisa Moh. Ihsan Rifasanto Monica Thiodora Limay Monita Valentine Silalahi Muhammad Ikhlasul Amal Sangadji MUHAMMAD RAYHAN Nadia Dewi Astuti Nafi’ah, Nafi’ah Nor Kamalia Novie Aprianti Novie Aprianti, Novie Nurashfia Nurashfia Nuril Fajriani Nurrahman, Tri Nurul Ikhsani Umar Pramitha, Selviana Rizky Priyawan Rachmadi Rahmadella, Afifah Renie Kumala Dewi Retno Andriati, Retno Retno Pudji Rahayu Rifasanto, Moh. Ihsan Saldy Rizky Saputra Saldy Rizky Saputra, Saldy Rizky Sari, Tiara Intan Permata Sherli Diana Silalahi, Monita Valentine Sundah, Serenada Audria Tri Putri, Deby Kania Utami, Juliyatin Putri Wenda Fitriati Noor Wenda Fitriati Noor, Wenda Fitriati Yunike Christanti Yusnida, Resha Yusrinie Wasiaturrahmah

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