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HEALTH BEHAVIOR AND DENTAL CARRIES IN COASTAL COMMUNITY: LITERATURE REVIEW Komarudin, Koko; Apriasari, Maharani Laillyza; Azizah, Aulia
Odonto : Dental Journal Vol 8, No 2 (2021): December 2021
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.8.2.74-80

Abstract

ABSTRACTBackground: The important role of coastal communities is not directly in line with their living conditions, which are mostly poor. Dental caries is basically a disease that is also suffered by the general public in Indonesia, even in the world. RISKESDAS 2018 shows the prevalence of caries in Indonesia is 88.8%. Dental caries is caused by the bacterium Streptococcus mutans. People who live in coastal areas are at risk of suffering from dental caries. Brushing behavior also has a relationship with the incidence of dental caries. Method: All articles reviewed were obtained from Pubmed, Science Direct, and Google Scholar with a period of 10 years in full text. using the keywords behavior, caries, and coastal area.Result: Based on reviews from several journals, it was found that the brushing behavior of coastal communities was good, but the frequency of brushing teeth was not appropriate and the behavior of using drinking water had no known fluoride content. There are variations in the category of dental caries at the age level of people in coastal areas.Conclusion: Knowledge and healthy behavior can reduce the risk of dental caries related to the behavior of coastal communities, so that life productivity can be much better than ever.
The social resilience of fishermen to oral diseases during the covid-19 pandemic in puger jember east java Komarudin, Koko; Mashud, Mustain; Andriati, Retno; Apriasari, Maharani Laillyza
Odonto : Dental Journal Vol 9, No 2 (2022): December 2022
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.9.2.279-289

Abstract

Background: Puger fishermen are able to survive and develop (resilience) in carrying out their activities in the form of natural disturbances and various diseases, especially during the COVID-19 pandemic. Oral diseases are the lowest of the seven diseases recorded at the Puger Health Center. This disease can make patients exposed to COVID-19 worse, but the Puger area is included in the green zone. The Purpose of this study is to analyze the effect of knowledge, behavior and health services to the social resilience ability of Puger fishermen.Method: It used a quantitative approach with the method of structural equation modelling (SEM). Confirmatory factor analysis tests and path analysis were conducted to analyze the effect among variables according to the research purpose. Questionnaires were distributed to fishermen who were sampled as respondents. Respondents amounted to 111 people. It used is simple random sampling.Result: The knowledge has a positive effect, but it is not significant to social resilience with a significance level (β= 0.001 p: 0.314>0.05), behavior has a positive effect, but it is not significant to social resiliance with a significance level (β= 0.005 p: 0.649>0.05) and Health service has a positive effect, but it is not significant to social resilience with a significance level (β= 0.003 p: 0.218>0.05).Conclusion: Puger Fishermen has social resilience ability to oral diseases underpinned by knowledge, behavior as well as health service. These variables have a positive correlation with resilience. Yet the level is not quite significant.
PREVALENCE OF ORAL DISEASES AT ULIN HOSPITAL BANJARMASIN IN 2017-2019 Apriasari, Maharani Laillyza; Sundah, Serenada Audria; Hamdani, Riky
Odonto : Dental Journal Vol 9, No 1 (2022): July 2022
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.9.1.62-72

Abstract

Background: Oral disease is a condition that causes lesions in the oral cavity, which can be influenced by age, gender, and level of education. Oral health is still becoming a problem in society that needs attention. According to basic health research 2018, the prevalence of oral disease in Indonesia remains considerably high reaching 57.6%. Oral diseases have practically been observed in Banjarmasin, yet no research has presented the prevalence of oral diseases in Ulin General Hospital, Banjarmasin. The purpose of this study was to determine the prevalence of oral disease in Ulin Hospital, Banjarmasin in 2017-2019Method: This research is a descriptive study using secondary data from medical record. Sampling method was carried out by total population sampling of oral disease patients who were treated at Oral and Dental Clinic, Ulin Hospital in 2017-2019Result: It showed that out of 102 oral disease patients, there were 78 patients suffering from recurrent aphthous stomatitis (76.5%), 8 patients from oral candidiasis (7.8%), 7 patients from oral squamous cell carcinoma (6.9%), 4 patients from oral submucous fibrosis (3.9%), 3 patients from burning mouth syndrome (2.9%), and 2 patients from allergic stomatitis (2%). Oral diseases were mostly found in over-45-years age group (54.9%), with the highest gender proportion is female reaching of 64.7%. Approximately 31.4% patients had completed high school education. Medical management was given to 60,8% patients with oral diseases.Conclusion: Recurrent aphthous stomatitis was the most common oral disease in Ulin Hospital, in 2017-2019, followed by oral candidiasis and oral squamous cell carcinoma.
ANTIBACTERIAL EFFECT OF KELAKAI LEAF EXTRACT (STENOCHLAENA PALUSTRIS (BURM) BEDD.) FOR INHIBITING ENTEROCOCCUS FAECALIS Firdaus, I Wayan Arya Krishnawan; Dewi, Nurdiana; Fuady, Ridwan Ichshalul; Apriasari, Maharani Laillyza
Odonto : Dental Journal Vol 9, No 1 (2022): July 2022
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.9.1.110-118

Abstract

Background: Root canal treatment is a stage of treating pulp infection by removing the necrotic tissue and eliminating microorganisms. Inadequate sterilization cause persistent root canal bacteria, including Enterococcus faecalis. The irrigation solution that has become the gold standard in root canal treatment is Sodium hypochlorite but it has some weaknesses. Kelakai leaf extract can be an alternative root canal irrigation because it has minimal side effects and antibacterial compounds such as flavonoid, saponin, alkaloid, and tannin.Methods: This research was a true experimental laboratory with posttest only and control group design. The research using 5 treatment groups with 3 replications, so that total sample was 15 samples. Group 1-4 were kelakai leaf extract concentrations of 25%, 50%, 75%, 100% and group 5 was Sodium hypochlorite 2,5%. The parameter measured was the diameter of the inhibition zone (mm) formed on MHA.Results: One Way Anova and Post Hoc LSD test results showed a significant difference between each treatment group of kelakai leaf extract compared with Sodium hypochlorite 2,5%. Kelakai leaf extract 25%, 50%, 75%, 100% concentrations, and Sodium hypochlorite 2,5% had an average inhibition zone diameter which were 9.47 mm, 14.64 mm, 17.91 mm, 21.24 mm, and 23.27 mm.Conclusion: Kelakai leaf extract concentrations of 25%, 50%, 75%, and 100% had inhibitory activity against Enterococcus faecalis but had not been equivalent to Sodium hypochlorite 2,5%.
ANTIFUNGUS EFFECTIVENESS OF CITRUS AMBLYCARPA PEEL, CITRUS HYSTRIX DC PEEL AND CITRUS AURANTIFOLIA PEEL EXTRACT (Against the Growth of Candida albicans) Yusnida, Resha; Saputera, Debby; Diana, Sherli; Dwi Kurniawan, Fajar Kusuma; Apriasari, Maharani Laillyza
Dentino: Jurnal Kedokteran Gigi Vol 10, No 1 (2025)
Publisher : FKG ULM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v10i1.22204

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Background: Candida albicans is a microorganism that causes many infections in the oral cavity. To treat infections caused by Candida albicans, antifungal therapy is needed. Alternative treatments for fungal infections can utilize traditional medicines, namely by using citrus amblycarpa peel extract, citrus hystrix DC peel, and citrus aurantifolia peel because they contain alkaloids, flavonoids, saponins, and tannins. Objective: Analyzing the antifungal effects of 100% concentration of citrus amblycarpa peel extract, 100% concentration of citrus hystrix DC peel, and 100% concentration of citrus aurantifolia peel on the growth of Candida albicans. Method: This study was a true experimental laboratory study with a post test only control group design, consisting of four treatment groups. Minimum Inhibitory Concentration (MIC) and Minimum Killing Concentration (MKC). Result: Parametric analysis using One Way Anova and Post Hoc Bonferroni KHM showed that there were significant differences in each treatment group and Post Hoc Games Howell test analysis showed that citrus amblycarpa peel extract showed no significant difference to citrus hystrik DC peel, citrus aurantifolia peel extract 100% concentration, while the aquades as a negative control there is a significant difference. Conclusion: Citrus amblycarpa peel extract, citrus hystrix DC peel extract, citrus aurantifolia peel 100% concentration, and aquades as a negative control had inhibitory effect on Candida albicans. Citrus amblycarpa peel extract concentration of 100% has killing power.
Pharmacotherapy And Behavioural-Modifying-Lifestyle For Oral Lesions Management In Multimorbid Patient Post-Pyelolithotomy: A Case Report Selviana Rizky Pramitha; Arissa Izzati; Maharani Laillyza Apriasari; Amy Nindia Carabelly; Dewi Puspitasari
Odonto : Dental Journal Vol 13, No 1 (2026): April 2026
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.13.1.%p

Abstract

Background: Chronic kidney disease (CKD), a recognized complication of pyelolithotomy along with multimorbidity in the elderly population, presents a higher incidence of oral lesions. Further damage to the renal vasculature interchangeably affects oral-systemic conditions. We report oral lesions management in MCC patient post-pyelolithotomy for better outcomes.  Case: A 65-year-old male patient complained of painful ulceration on the atrophic tongue for two weeks with a fair oral hygiene score. The condition had been managed with various topical agents alternately with no improvement. There was a history of pyelolithotomy and emergency room admission. Laboratory examination presented diabetes mellitus, stage 3B kidney disease and anemia of chronic disease. A diagnosis of ulcerative-type uremic stomatitis with atrophic glossitis in multimorbid patient was obtained. Pharmacotherapy of oral lesion including aloe vera extract mouthwash and povidone-iodine mouthwash showed improvement on the following day. Behavioural-modifying lifestyle involved physical activity, healthy eating, and adherence to treatment (oral hygiene maintenance and regular dental appointment). Systemic conditions were managed by multidiscipline treatment with Internal Medicine. Conclusion: Pharmacotherapy and behavioral modifying lifestyle may support a better prognosis for oral manifestation in multimorbid patient post pyelolithotomy
Pharmacotherapy And Behavioural-Modifying-Lifestyle For Oral Lesions Management In Multimorbid Patient Post-Pyelolithotomy: A Case Report Pramitha, Selviana Rizky; Izzati, Arissa; Apriasari, Maharani Laillyza; Carabelly, Amy Nindia; Puspitasari, Dewi
Odonto : Dental Journal Vol 13, No 1 (2026): April 2026
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.13.1.%p

Abstract

Background: Chronic kidney disease (CKD), a recognized complication of pyelolithotomy along with multimorbidity in the elderly population, presents a higher incidence of oral lesions. Further damage to the renal vasculature interchangeably affects oral-systemic conditions. We report oral lesions management in MCC patient post-pyelolithotomy for better outcomes.  Case: A 65-year-old male patient complained of painful ulceration on the atrophic tongue for two weeks with a fair oral hygiene score. The condition had been managed with various topical agents alternately with no improvement. There was a history of pyelolithotomy and emergency room admission. Laboratory examination presented diabetes mellitus, stage 3B kidney disease and anemia of chronic disease. A diagnosis of ulcerative-type uremic stomatitis with atrophic glossitis in multimorbid patient was obtained. Pharmacotherapy of oral lesion including aloe vera extract mouthwash and povidone-iodine mouthwash showed improvement on the following day. Behavioural-modifying lifestyle involved physical activity, healthy eating, and adherence to treatment (oral hygiene maintenance and regular dental appointment). Systemic conditions were managed by multidiscipline treatment with Internal Medicine. Conclusion: Pharmacotherapy and behavioral modifying lifestyle may support a better prognosis for oral manifestation in multimorbid patient post pyelolithotomy
Studi In Silico Interaksi Senyawa Aktif Daun Tabat Barito terhadap iNOS sebagai Target Molekuler Inflamasi Mukosa Mulut Pramitha, Selviana Rizky; Apriasari, Maharani Laillyza
Sinnun Maxillofacial Journal Vol. 8 No. 01 (2026): April 2026
Publisher : Fakultas Kedokteran Gigi Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/smj.v8i01.230

Abstract

Pendahuluan: Enzim inducible Nitric Oxide Synthase (iNOS) memegang peran sentral pada proses inflamasi di mana overekspresinya berkorelasi dengan peningkatan kerusakan jaringan, meliputi mukosa rongga mulut yang terpapar berulang dengan stimulus eksternal. Pengembangan senyawa nontoksik yang secara selektif mengatur iNOS tanpa memengaruhi isoenzim lain untuk perbaikan jaringan menjadi tantangan dalam dunia medis. Ekstrak daun Tabat Barito (Ficus deltoidea J.) dilaporkan non toksik dan beberapa fitokimianya memiliki efek antiinflamasi sehingga berpotensi untuk inhibitor iNOS. Tujuan: Menganalisis interaksi molekuler senyawa aktif daun Tabat Barito terhadap iNOS melalui pendekatan molecular docking sebagai target inflamasi mukosa mulut. Bahan dan Metode: Lima fitokimia diuji melalui molecular docking terhadap iNOS. Struktur kristal iNOS manusia (PDB ID: 1NSI) divalidasi menggunakan SAVESv6.1, ProSA, dan SWISS-MODEL. Profil farmakokinetik dianalisis dengan SwissADME. Persiapan protein dan ligan dilakukan dengan AutoDockTools (MGLTools 1.5.7), dan docking dianalisis menggunakan PyRx. Visualisasi interaksi menggunakan BIOVIA Discovery Studio Visualizer Client 2025. Hasil: Afinitas ikatan ligan bervariasi, di mana luteolin dan (+)-epicatechin menunjukkan ikatan terkuat, melampaui inhibitor standar L-NAME dan L-NMMA. Ligan berafinitas tinggi membentuk interaksi penting dengan residu situs katalitik serta beberapa ikatan hidrogen yang menstabilkan orientasi ligan. Analisis ADME menunjukkan profil drug-likeness yang baik untuk luteolin, epicatechin, dan vanillic acid, sedangkan quinic acid dan inhibitor standar memiliki penyerapan rendah akibat polaritas tinggi. Kesimpulan: Kelima fitokimia ekstrak daun Tabat Barito menunjukkan interaksi dengan iNOS, di mana vanillic acid merupakan senyawa dasar yang paling cocok untuk penggunaan oral dan topikal, sedangkan luteolin dan epicatechin menunjukkan potensi modulasi iNOS tertinggi, tetapi memerlukan modifikasi desain molekul.
EFFECT OF FICUS DELTOIDEA JACK. TO NEUTROPHIL AND MACROPHAGE CELLS IN ORAL WOUND HEALING Apriasari, Maharani Laillyza; Firdaus, I Wayan Arya Krishnawan; Sari Fitri, Rahayu Wida; Ishmah, Hana Nur; Pramitha, Selviana Rizky; Mahamad Apandi, Nurul Inaas
Dentino: Jurnal Kedokteran Gigi Vol 11, No 1 (2026)
Publisher : FKG ULM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v11i1.26130

Abstract

Background: Oral mucosal wounds require effective inflammatory control for optimal healing. However, conventional agents such as povidone-iodine may cause irritation and cytotoxicity, limiting their use. Ficus deltoidea, a medicinal plant from Kalimantan, possesses antimicrobial, antioxidant, and anti-inflammatory properties, making it a promising alternative for oral wound therapy. Objectives: To evaluate the effect of Ficus deltoidea leaf extract gel on neutrophil and macrophage cells in oral mucosal wound healing. Methods: A true experimental posttest-only control group study was conducted on 48 male Wistar rats. Standardized buccal mucosal wounds were treated with Ficus deltoidea J. leaf extract gel (GEDTB) 5%, 10%, 15% or gel base (control). Animals were sacrificed on days 1, 3, and 7, and neutrophil and macrophage counts were assessed histopathologically. Data were analyzed using two-way ANOVA with Bonferroni post hoc. Results: Neutrophil counts decreased significantly over time in all groups, with a faster reduction in extract-treated groups, particularly at 15%. On day 1, the control group had the highest neutrophil count, significantly greater than the 15% group (p<0.05), while by day 7, all treatment groups showed significantly lower neutrophil levels than control. Macrophage counts increased from day 1, peaked on day 3—highest in the 15% group—and declined significantly by day 7. Both treatment and time had significant effects on neutrophil and macrophage counts (p<0.05), with a significant interaction observed for macrophages. Conclusion: Ficus deltoidea J. leaf extract gel effectively modulates inflammatory cell by accelerating neutrophil reduction and enhancing macrophage activity in oral wound healing.Keywords: Anti-inflammatory activity, Ficus deltoidea jack.,Macrophages, Neutrophils, Oral wound healing
In Silico Model of Musa acuminata Stem as an Anticancer on Oral Squamous Cell Carcinoma against EGFR Rachmayani, Nevrila Dewi; Carabelly, Amy Nindia; Firdaus, I Wayan Arya Krishnawan; Apriasari, Maharani Laillyza; Utami, Juliyatin Putri
Journal of Dentistry Indonesia Vol. 33, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Oral squamous cell carcinoma (OSCC) is characterized by overexpression of the epidermal growth factor receptor (EGFR). Citral, eucalyptol, and caffeic acid phenethyl ester (CAPE), which are derived from Musa acuminata, have shown anticancer activity. This study evaluated the potential of citral, eucalyptol, and CAPE from Musa acuminata as anticancer agents for OSCC by targeting EGFR using an in silico approach. Methods: Potential biological activity was predicted using Prediction of Activity Spectra for Substances (PASS) Online. Molecular docking was conducted with AutoDock Vina, and BIOVIA Discovery Studio was used to analyze binding affinity, interaction types, and bond distances between the compounds and active-site residues of EGFR. Results: CAPE showed the strongest binding affinity (-8.6 kcal/mol), whereas citral and eucalyptol each showed a binding affinity of -5.4 kcal/mol. CAPE formed a conventional hydrogen bond with CYS775 at 2.65 Å and hydrophobic interactions with PHE856, LEU777, and MET766, through π-alkyl and π-π T-shaped interactions. These interaction distances were within the effective range of <3.5 Å, indicating a stable ligand-protein complex. Conclusions: These in silico findings suggest that CAPE derived from Musa acuminata is a promising anticancer candidate for OSCC through its interaction with EGFR.
Co-Authors Adhiya, Geyanina Melda Agung Satria Wardhana Almadina Latanza Amy Nindia Carabelly Amy Nindia Carabelly Anita Fitriani Annisa Vara Nurdianty Aprilyani, Nur Ariska Endariantari Arissa Izzati Asphia Rahmah Astuti, Nadia Dewi Aulia Azizah Aulia Rahma Annisa Bagus Soebadi Beta Widya Oktiani Beta Widya Oktiani Cane Lukisari, Cane Debby Saputera, Debby Destri Khusnul Khotimah Dewi Nurdiana Dewi Puspitasari Dewi Puspitasari Dewi Rahayu Diah Savitri Ernawati Dita Permatasari Dita Permatasari Dwi Kurniawan, Fajar Kusuma Dwi Setyaningtyas, Dwi Eko Suhartono Eriwati, Yosi Kusuma Erni Marlina Fajriani, Nuril Firdaus, I Wayan Arya Krishnawan Fuady, Ridwan Ichshalul Hadi Waskito Hamdani, Riky Hatta, Isnur Hening Tuti Hendarti Husma, Emma Annahal I Wayan Arya K. Firdaus I Wayan Arya Khrisnawan Firdaus I Wayan Arya Krishnawan Firdaus I Wayan Arya Krisnawan Firdaus Ichrom Nahzi, Muhammad Yanuar Ika Kustiyah Oktaviyanti Ishmah, Hana Nur Izzati, Arissa Khairunnisa Amalia Pratami Komarudin, Koko Krishnawan Firdaus, I Wayan Arya Kurnia Fatwati Lia Yulia Budiarti M. Jusri M. Ridhotama Wibowo Mahamad Apandi, Nurul Inaas Maria Tanumihardja, Maria Marina Arum Syahadati Mashud, Mustain Melisa Budipramana, Melisa Moh. Ihsan Rifasanto Monica Thiodora Limay Monita Valentine Silalahi Muhammad Ikhlasul Amal Sangadji MUHAMMAD RAYHAN Nadia Dewi Astuti Nafi’ah, Nafi’ah Nor Kamalia Novie Aprianti Novie Aprianti, Novie Nurashfia Nurashfia Nuril Fajriani Nurrahman, Tri Nurul Ikhsani Umar Pramitha, Selviana Rizky Priyawan Rachmadi Rachmayani, Nevrila Dewi Rahmadella, Afifah Renie Kumala Dewi Retno Andriati, Retno Retno Pudji Rahayu Rifasanto, Moh. Ihsan Saldy Rizky Saputra Saldy Rizky Saputra, Saldy Rizky Sari Fitri, Rahayu Wida Sari, Tiara Intan Permata Selviana Rizky Pramitha Sherli Diana Silalahi, Monita Valentine Sundah, Serenada Audria Tri Putri, Deby Kania Utami, Juliyatin Putri Wenda Fitriati Noor Wenda Fitriati Noor, Wenda Fitriati Yunike Christanti Yusnida, Resha Yusrinie Wasiaturrahmah