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All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Journal of Dentistry Indonesia Jurnal Berkala Epidemiologi STOMATOGNATIC- Jurnal Kedokteran Gigi ODONTO Dental Journal Dentino: Jurnal Kedokteran Gigi Berkala Kedokteran Dental Journal (Majalah Kedokteran Gigi) Padjadjaran Journal of Dentistry Dentin Jurnal Insan Farmasi Indonesia Jurnal Pengabdian Ilung (Inovasi Lahan Basah Unggul) Denta: Jurnal Kedokteran Gigi Odonto dental journal Lentera Negeri
Maharani Laillyza Apriasari
Departement Of Oral Medicine, Faculty Of Dentistry, Lambung Mangkurat University
Agriculture, Biological Sciences & Forestry Arts Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Energy Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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PREVALENCE OF ORAL DISEASES AT ULIN HOSPITAL BANJARMASIN IN 2017-2019 Apriasari, Maharani Laillyza; Sundah, Serenada Audria; Hamdani, Riky
Odonto : Dental Journal Vol 9, No 1 (2022): July 2022
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.9.1.62-72

Abstract

Background: Oral disease is a condition that causes lesions in the oral cavity, which can be influenced by age, gender, and level of education. Oral health is still becoming a problem in society that needs attention. According to basic health research 2018, the prevalence of oral disease in Indonesia remains considerably high reaching 57.6%. Oral diseases have practically been observed in Banjarmasin, yet no research has presented the prevalence of oral diseases in Ulin General Hospital, Banjarmasin. The purpose of this study was to determine the prevalence of oral disease in Ulin Hospital, Banjarmasin in 2017-2019Method: This research is a descriptive study using secondary data from medical record. Sampling method was carried out by total population sampling of oral disease patients who were treated at Oral and Dental Clinic, Ulin Hospital in 2017-2019Result: It showed that out of 102 oral disease patients, there were 78 patients suffering from recurrent aphthous stomatitis (76.5%), 8 patients from oral candidiasis (7.8%), 7 patients from oral squamous cell carcinoma (6.9%), 4 patients from oral submucous fibrosis (3.9%), 3 patients from burning mouth syndrome (2.9%), and 2 patients from allergic stomatitis (2%). Oral diseases were mostly found in over-45-years age group (54.9%), with the highest gender proportion is female reaching of 64.7%. Approximately 31.4% patients had completed high school education. Medical management was given to 60,8% patients with oral diseases.Conclusion: Recurrent aphthous stomatitis was the most common oral disease in Ulin Hospital, in 2017-2019, followed by oral candidiasis and oral squamous cell carcinoma.
ANTIBACTERIAL EFFECT OF KELAKAI LEAF EXTRACT (STENOCHLAENA PALUSTRIS (BURM) BEDD.) FOR INHIBITING ENTEROCOCCUS FAECALIS Firdaus, I Wayan Arya Krishnawan; Dewi, Nurdiana; Fuady, Ridwan Ichshalul; Apriasari, Maharani Laillyza
Odonto : Dental Journal Vol 9, No 1 (2022): July 2022
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.9.1.110-118

Abstract

Background: Root canal treatment is a stage of treating pulp infection by removing the necrotic tissue and eliminating microorganisms. Inadequate sterilization cause persistent root canal bacteria, including Enterococcus faecalis. The irrigation solution that has become the gold standard in root canal treatment is Sodium hypochlorite but it has some weaknesses. Kelakai leaf extract can be an alternative root canal irrigation because it has minimal side effects and antibacterial compounds such as flavonoid, saponin, alkaloid, and tannin.Methods: This research was a true experimental laboratory with posttest only and control group design. The research using 5 treatment groups with 3 replications, so that total sample was 15 samples. Group 1-4 were kelakai leaf extract concentrations of 25%, 50%, 75%, 100% and group 5 was Sodium hypochlorite 2,5%. The parameter measured was the diameter of the inhibition zone (mm) formed on MHA.Results: One Way Anova and Post Hoc LSD test results showed a significant difference between each treatment group of kelakai leaf extract compared with Sodium hypochlorite 2,5%. Kelakai leaf extract 25%, 50%, 75%, 100% concentrations, and Sodium hypochlorite 2,5% had an average inhibition zone diameter which were 9.47 mm, 14.64 mm, 17.91 mm, 21.24 mm, and 23.27 mm.Conclusion: Kelakai leaf extract concentrations of 25%, 50%, 75%, and 100% had inhibitory activity against Enterococcus faecalis but had not been equivalent to Sodium hypochlorite 2,5%.
Pharmacotherapy And Behavioural-Modifying-Lifestyle For Oral Lesions Management In Multimorbid Patient Post-Pyelolithotomy: A Case Report Selviana Rizky Pramitha; Arissa Izzati; Maharani Laillyza Apriasari; Amy Nindia Carabelly; Dewi Puspitasari
Odonto : Dental Journal Vol 13, No 1 (2026): April 2026
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.13.1.87-98

Abstract

Background: Chronic kidney disease (CKD), a recognized complication of pyelolithotomy along with multimorbidity in the elderly population, presents a higher incidence of oral lesions. Further damage to the renal vasculature interchangeably affects oral-systemic conditions. We report oral lesions management in MCC patient post-pyelolithotomy for better outcomes.  Case: A 65-year-old male patient complained of painful ulceration on the atrophic tongue for two weeks with a fair oral hygiene score. The condition had been managed with various topical agents alternately with no improvement. There was a history of pyelolithotomy and emergency room admission. Laboratory examination presented diabetes mellitus, stage 3B kidney disease and anemia of chronic disease. A diagnosis of ulcerative-type uremic stomatitis with atrophic glossitis in multimorbid patient was obtained. Pharmacotherapy of oral lesion including aloe vera extract mouthwash and povidone-iodine mouthwash showed improvement on the following day. Behavioural-modifying lifestyle involved physical activity, healthy eating, and adherence to treatment (oral hygiene maintenance and regular dental appointment). Systemic conditions were managed by multidiscipline treatment with Internal Medicine. Conclusion: Pharmacotherapy and behavioral modifying lifestyle may support a better prognosis for oral manifestation in multimorbid patient post pyelolithotomy
In Silico Model of Musa acuminata Stem as an Anticancer on Oral Squamous Cell Carcinoma against EGFR Rachmayani, Nevrila Dewi; Carabelly, Amy Nindia; Firdaus, I Wayan Arya Krishnawan; Apriasari, Maharani Laillyza; Utami, Juliyatin Putri
Journal of Dentistry Indonesia Vol. 33, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Oral squamous cell carcinoma (OSCC) is characterized by overexpression of the epidermal growth factor receptor (EGFR). Citral, eucalyptol, and caffeic acid phenethyl ester (CAPE), which are derived from Musa acuminata, have shown anticancer activity. This study evaluated the potential of citral, eucalyptol, and CAPE from Musa acuminata as anticancer agents for OSCC by targeting EGFR using an in silico approach. Methods: Potential biological activity was predicted using Prediction of Activity Spectra for Substances (PASS) Online. Molecular docking was conducted with AutoDock Vina, and BIOVIA Discovery Studio was used to analyze binding affinity, interaction types, and bond distances between the compounds and active-site residues of EGFR. Results: CAPE showed the strongest binding affinity (-8.6 kcal/mol), whereas citral and eucalyptol each showed a binding affinity of -5.4 kcal/mol. CAPE formed a conventional hydrogen bond with CYS775 at 2.65 Å and hydrophobic interactions with PHE856, LEU777, and MET766, through π-alkyl and π-π T-shaped interactions. These interaction distances were within the effective range of <3.5 Å, indicating a stable ligand-protein complex. Conclusions: These in silico findings suggest that CAPE derived from Musa acuminata is a promising anticancer candidate for OSCC through its interaction with EGFR.
Patient trust dynamics in ai-based telemedicine: a social psychological systematic review Alexander Sitepu; Maharani Laillyza Apriasari; Alvi Yasmina; Rosihan Adhani
Lentera Negeri Vol. 7 No. 1 (2026): Lentera Negeri
Publisher : Indonesian Institute For Counseling, Education and Therapy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29210/992460

Abstract

Background: Artificial intelligence (AI)-based telemedicine increasingly supports remote diagnosis, clinical decision support, and technology-mediated health communication. However, patient trust remains theoretically fragmented because prior studies often treat it as a general adoption variable rather than as a social psychological process. This review aimed to synthesize how patient trust in AI-based telemedicine is formed through social cognition, human-AI interaction, and institutional legitimacy. Method: A systematic literature review was conducted following PRISMA 2020. Scopus was the primary database, while PubMed and Google Scholar were used as complementary sources. Searches covered peer-reviewed literature published from 2015 to 2025 using Boolean combinations of trust, social acceptance, social psychology, human-AI interaction, artificial intelligence, telemedicine, telehealth, and virtual care. Two reviewers independently screened records, extracted data using a predefined matrix, and appraised empirical studies using the Mixed Methods Appraisal Tool, while conceptual papers were assessed for relevance, theoretical clarity, and contribution. Heterogeneity was handled through narrative thematic synthesis. Results: Eleven studies/reports were included. Three trust dimensions emerged: individual cognitive appraisal, including explainability, perceived risk, and prior experience; interactional attribution, including AI agency, role clarity, and communication quality; and socio-structural legitimation, including privacy, fairness, bias mitigation, and institutional governance. Human-AI interaction functioned as the experiential channel through which trust was calibrated, while social acceptance operated as a collective condition shaped by norms, professional identity, and legitimacy. Conclusion: Patient trust in AI-based telemedicine is a multilevel social psychological process. Sustainable implementation requires transparent design, privacy assurance, bias governance, and clear alignment between AI systems and clinical roles.
Pharmacotherapy And Behavioural-Modifying-Lifestyle For Oral Lesions Management In Multimorbid Patient Post-Pyelolithotomy: A Case Report Selviana Rizky Pramitha; Arissa Izzati; Maharani Laillyza Apriasari; Amy Nindia Carabelly; Dewi Puspitasari
Odonto : Dental Journal Vol 13, No 1 (2026): April 2026
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.13.1.87-98

Abstract

Background: Chronic kidney disease (CKD), a recognized complication of pyelolithotomy along with multimorbidity in the elderly population, presents a higher incidence of oral lesions. Further damage to the renal vasculature interchangeably affects oral-systemic conditions. We report oral lesions management in MCC patient post-pyelolithotomy for better outcomes.  Case: A 65-year-old male patient complained of painful ulceration on the atrophic tongue for two weeks with a fair oral hygiene score. The condition had been managed with various topical agents alternately with no improvement. There was a history of pyelolithotomy and emergency room admission. Laboratory examination presented diabetes mellitus, stage 3B kidney disease and anemia of chronic disease. A diagnosis of ulcerative-type uremic stomatitis with atrophic glossitis in multimorbid patient was obtained. Pharmacotherapy of oral lesion including aloe vera extract mouthwash and povidone-iodine mouthwash showed improvement on the following day. Behavioural-modifying lifestyle involved physical activity, healthy eating, and adherence to treatment (oral hygiene maintenance and regular dental appointment). Systemic conditions were managed by multidiscipline treatment with Internal Medicine. Conclusion: Pharmacotherapy and behavioral modifying lifestyle may support a better prognosis for oral manifestation in multimorbid patient post pyelolithotomy
EFFECT OF FICUS DELTOIDEA JACK. TO NEUTROPHIL AND MACROPHAGE CELLS IN ORAL WOUND HEALING Maharani Laillyza Apriasari; I Wayan Arya Krishnawan Firdaus; Rahayu Wida Sari Fitri; Hana Nur Ishmah; Selviana Rizky Pramitha; Nurul Inaas Mahamad Apandi
Dentino: Jurnal Kedokteran Gigi Vol 11, No 1 (2026)
Publisher : FKG ULM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v11i1.26130

Abstract

Background: Oral mucosal wounds require effective inflammatory control for optimal healing. However, conventional agents such as povidone-iodine may cause irritation and cytotoxicity, limiting their use. Ficus deltoidea, a medicinal plant from Kalimantan, possesses antimicrobial, antioxidant, and anti-inflammatory properties, making it a promising alternative for oral wound therapy. Objectives: To evaluate the effect of Ficus deltoidea leaf extract gel on neutrophil and macrophage cells in oral mucosal wound healing. Methods: A true experimental posttest-only control group study was conducted on 48 male Wistar rats. Standardized buccal mucosal wounds were treated with Ficus deltoidea J. leaf extract gel (GEDTB) 5%, 10%, 15% or gel base (control). Animals were sacrificed on days 1, 3, and 7, and neutrophil and macrophage counts were assessed histopathologically. Data were analyzed using two-way ANOVA with Bonferroni post hoc. Results: Neutrophil counts decreased significantly over time in all groups, with a faster reduction in extract-treated groups, particularly at 15%. On day 1, the control group had the highest neutrophil count, significantly greater than the 15% group (p<0.05), while by day 7, all treatment groups showed significantly lower neutrophil levels than control. Macrophage counts increased from day 1, peaked on day 3—highest in the 15% group—and declined significantly by day 7. Both treatment and time had significant effects on neutrophil and macrophage counts (p<0.05), with a significant interaction observed for macrophages. Conclusion: Ficus deltoidea J. leaf extract gel effectively modulates inflammatory cell by accelerating neutrophil reduction and enhancing macrophage activity in oral wound healing.Keywords: Anti-inflammatory activity, Ficus deltoidea jack.,Macrophages, Neutrophils, Oral wound healing
ANTIFUNGUS EFFECTIVENESS OF CITRUS AMBLYCARPA PEEL, CITRUS HYSTRIX DC PEEL AND CITRUS AURANTIFOLIA PEEL EXTRACT (Against the Growth of Candida albicans) Resha Yusnida; Debby Saputera; Sherli Diana; Fajar Kusuma Dwi Kurniawan; Maharani Laillyza Apriasari
Dentino: Jurnal Kedokteran Gigi Vol 10, No 1 (2025)
Publisher : FKG ULM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v10i1.22204

Abstract

Background: Candida albicans is a microorganism that causes many infections in the oral cavity. To treat infections caused by Candida albicans, antifungal therapy is needed. Alternative treatments for fungal infections can utilize traditional medicines, namely by using citrus amblycarpa peel extract, citrus hystrix DC peel, and citrus aurantifolia peel because they contain alkaloids, flavonoids, saponins, and tannins. Objective: Analyzing the antifungal effects of 100% concentration of citrus amblycarpa peel extract, 100% concentration of citrus hystrix DC peel, and 100% concentration of citrus aurantifolia peel on the growth of Candida albicans. Method: This study was a true experimental laboratory study with a post test only control group design, consisting of four treatment groups. Minimum Inhibitory Concentration (MIC) and Minimum Killing Concentration (MKC). Result: Parametric analysis using One Way Anova and Post Hoc Bonferroni KHM showed that there were significant differences in each treatment group and Post Hoc Games Howell test analysis showed that citrus amblycarpa peel extract showed no significant difference to citrus hystrik DC peel, citrus aurantifolia peel extract 100% concentration, while the aquades as a negative control there is a significant difference. Conclusion: Citrus amblycarpa peel extract, citrus hystrix DC peel extract, citrus aurantifolia peel 100% concentration, and aquades as a negative control had inhibitory effect on Candida albicans. Citrus amblycarpa peel extract concentration of 100% has killing power.
EFFECT OF GELAM LEAF EXTRACT (Melaleuca cajuputi) AND TRICALCIUM SILICATE CEMENT AS DIRECT PULP CAPPING Emma Annahal Husma; Sherli Diana; Debby Saputera; Maharani Laillyza Apriasari; Tri Nurrahman
Dentino: Jurnal Kedokteran Gigi Vol 9, No 2 (2024)
Publisher : FKG ULM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v9i2.20397

Abstract

Background: Reversible pulpitis is mild pulp inflammation. The treatment is direct pulpcapping. Tricalcium silicate cement has been better at inducing reparative dentin than other materials. Tricalcium silicate cement can cause inflammation 1-2 weeks after application, that natural ingredients need to improve the quality. Tricalcium silicate cement can be combined with galam leaf extract which contains anti-inflammatory properties by accelerating lymphocyte cells. Purpose: To analyzed the effect of gelam leaf extract (Melaleuca cajuputi) concentration of 100% and Tricalcium Silicate Cement on the number of lymphocyte cells on day 3 and 5 in direct pulp capping treatment. Methods: This research is a true experimental study with a post test-only with control design. This study used 24 Wistar rats, divided into 3 treatment groups with 2 different days, namely the group given a combination of Gelam leaf 100% + tricalcium silicate cement, tricalcium silicate cement as positive control, and without treatment as negative control. Results: One-way ANOVA test obtained p value=0.00<0.05, which indicates there is a significant difference between each group. Post Hoc Bonferroni test showed significant difference between galam leaf extract and tricalcium silicate cement, tricalcium silicate cement, and no treatment on days 3 and 5. Conclusion: The combination of galam leaf extract and tricalcium silicate cement can increase the number of lymphocyte cells on day 3 of pulp inflammation and reduce the number of lymphocyte cells on day 5 more effectively than tricalcium silicate cement and without treatment on days 3 and 5 so that the healing process is faster.
TETRACYCLINE MOUTHWASH AS ORAL CAVITY ULCER THERAPY IN PATIENTS WITH A HISTORY OF ALLERGIES Cane Lukisari; Dwi Setyaningtyas; Nafi’ah Nafi’ah; Maharani Laillyza Apriasari
Dentino: Jurnal Kedokteran Gigi Vol 9, No 1 (2024)
Publisher : FKG ULM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v9i1.18862

Abstract

Background: One of the allergic reactions in the oral mucosa is ulceration caused by IgE-mediated reactions to food substances or non-IgE-mediated reactions and non-immunological mechanisms. Ulceration is a damage to the epithelium of the oral cavity that affects the nerve endings in the lamina propria layer so that it causes pain or heat that requires treatment and therapy. Objective: To report the occurrence of ulcers due to food allergies and therapy with tetracycline mouthwash 0.25% solution. Case: A 22-year-old female patient came with complaints of a small ulcer on the inside of the gums and the entire upper and lower lips and a numb and dry tongue. The patient always experiences an ulcer every time he eats seafood and certain foods that the patient cannot mention because it happens so often and every time an ulcer appears it will continue to get bigger. Management: Patients are advised to avoid allergens and refer for a complete blood allergy test and Ig E. Tetracycline mouthwash 0.25% solution was given to be rinsed three times a day. And added supportive therapy, giving multivitamins. Conclusion: Tetracycline mouthwash has antimicrobial properties and properties as inhibitors of tissue metalloproteinases (TIMPs) can accelerate healing time and ulceration does not continue to get bigger, reduce taste and pain, according to the theory it can reduce secondary speed limits and duration. inhibits collagenase. Keyword: Allergy, Mouthwash, Tetracycline, Ulcer
Co-Authors Adhiya, Geyanina Melda Agung Satria Wardhana Alexander Sitepu Almadina Latanza Alvi Yasmina Amy Nindia Carabelly Amy Nindia Carabelly Anita Fitriani Annisa Vara Nurdianty Aprilyani, Nur Ariska Endariantari Arissa Izzati Asphia Rahmah Astuti, Nadia Dewi Aulia Azizah Aulia Rahma Annisa Bagus Soebadi Beta Widya Oktiani Beta Widya Oktiani Cane Lukisari Debby Saputera, Debby Destri Khusnul Khotimah Dewi Nurdiana Dewi Puspitasari Dewi Rahayu Diah Savitri Ernawati Dita Permatasari Dita Permatasari Dwi Kurniawan, Fajar Kusuma Dwi Setyaningtyas Eko Suhartono Emma Annahal Husma Eriwati, Yosi Kusuma Erni Marlina Fajriani, Nuril Firdaus, I Wayan Arya Krishnawan Fuady, Ridwan Ichshalul Hadi Waskito Hamdani, Riky Hana Nur Ishmah Hatta, Isnur Hening Tuti Hendarti I Wayan Arya K. Firdaus I Wayan Arya Khrisnawan Firdaus I Wayan Arya Krishnawan Firdaus I Wayan Arya Krishnawan Firdaus I Wayan Arya Krisnawan Firdaus Ichrom Nahzi, Muhammad Yanuar Ika Kustiyah Oktaviyanti Khairunnisa Amalia Pratami Komarudin, Koko Krishnawan Firdaus, I Wayan Arya Kurnia Fatwati Lia Yulia Budiarti M. Jusri M. Ridhotama Wibowo Maria Tanumihardja, Maria Marina Arum Syahadati Mashud, Mustain Melisa Budipramana, Melisa Moh. Ihsan Rifasanto Monica Thiodora Limay Monita Valentine Silalahi Muhammad Ikhlasul Amal Sangadji MUHAMMAD RAYHAN Nadia Dewi Astuti Nafi’ah Nafi’ah Nor Kamalia Novie Aprianti Novie Aprianti, Novie Nurashfia Nurashfia Nuril Fajriani Nurrahman, Tri Nurul Ikhsani Umar Nurul Inaas Mahamad Apandi Pramitha, Selviana Rizky Priyawan Rachmadi Rachmayani, Nevrila Dewi Rahayu Wida Sari Fitri Rahmadella, Afifah Renie Kumala Dewi Resha Yusnida Retno Andriati, Retno Retno Pudji Rahayu Rifasanto, Moh. Ihsan Rosihan Adhani Saldy Rizky Saputra Saldy Rizky Saputra, Saldy Rizky Sari, Tiara Intan Permata Selviana Rizky Pramitha Selviana Rizky Pramitha Sherli Diana Silalahi, Monita Valentine Sundah, Serenada Audria Tri Putri, Deby Kania Utami, Juliyatin Putri Wenda Fitriati Noor Wenda Fitriati Noor, Wenda Fitriati Yunike Christanti Yusrinie Wasiaturrahmah