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All Journal Journal of Food and Pharmaceutical Science Jurnal Ilmiah Farmasi EKSAKTA: Journal of Sciences and Data Analysis Indonesian Journal of Pharmaceutical Science and Technology MEDISAINS Asian Journal of Innovation and Entrepreneurship (AJIE) JURNAL PHARMASCIENCE Majalah Obat Tradisional MPI (Media Pharmaceutica Indonesiana) INDONESIAN JOURNAL OF PHARMACY Journal of Islamic Pharmacy Jurnal Farmasi Sains dan Komunitas Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) CHEESA: Chemical Engineering Research Articles JSFK (Jurnal Sains Farmasi & Klinis) AMALIAH: JURNAL PENGABDIAN KEPADA MASYARAKAT Jurnal Abdimas Madani dan Lestari (JAMALI) Jurnal Ners Medfarm: Jurnal Farmasi dan Kesehatan Journal of Pharmaceutical and Health Research Hydrogen: Jurnal Kependidikan Kimia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Medical Sains : Jurnal Ilmiah Kefarmasian Khazanah: Jurnal Mahasiswa SWARNA Jurnal Farmasi Kryonaut Journal of Food and Pharmaceutical Sciences Parapemikir Jurnal Ilmiah Farmasi Borneo Journal of Pharmacy Medical Sains : Jurnal Ilmiah Kefarmasian Journal of Pharmascience
Lutfi Chabib, Lutfi
Department Of Pharmacy, Islamic University Of Indonesia
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Ultra-High Performance Liquid Chromatography Method Validation for Micro-dissolution Analysis of Ketoconazole in Alginate-Acacia Gum Composite Capsules Lumakso, Fajar Aji; Annisa, Viviane; Cermenda, Riska; Chabib, Lutfi
Journal of Food and Pharmaceutical Sciences Vol 13, No 4 (2025): J.Food.Pharm.Sci
Publisher : Integrated Research and Testing Laboratory (LPPT) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.24078

Abstract

Ketoconazole, a BCS Class 2 antifungal drug, has good absorption but suffers from low solubility and poor bioavailability. To address this, a natural polymer-based matrix of alginate and acacia gum was formulated to enhance dissolution. This study aimed to validate a Ultra High Performance Liquid Chromatography method for analyzing ketoconazole content in micro-dissolution testing of capsule formulations. The method employed a C18 column with a mobile phase of acetonitrile:WFI (0.15% TEA, pH 3.5; 50:50) at 1 mL/min and detection at 265 nm. Validation demonstrated compliance with selectivity, linearity (r = 0.9996), sensitivity (LoD 6.51 µg/mL; LoQ 19.74 µg/mL), accuracy (99.6–101.3%), and precision (<2%, except one interday result at 2.08%). Micro-dissolution testing showed sustained ketoconazole release, exceeding 100% within 240 minutes. Data modeling (performed using DDSolver) indicated comparable fit for the Higuchi (R²_adj = 0.96) and Korsmeyer (R²_adj = 0.93) models, suggesting diffusion-controlled release of ketokonazole. The validated UHPLC method is suitable for micro-dissolution studies, and the alginate-acacia gum formulation effectively modulates drug release.
Ultra-High Performance Liquid Chromatography Method Validation for Micro-dissolution Analysis of Ketoconazole in Alginate-Acacia Gum Composite Capsules Lumakso, Fajar Aji; Annisa, Viviane; Cermenda, Riska; Chabib, Lutfi
Journal of Food and Pharmaceutical Sciences Vol 13, No 4 (2025): J.Food.Pharm.Sci
Publisher : Integrated Research and Testing Laboratory (LPPT) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.24078

Abstract

Ketoconazole, a BCS Class 2 antifungal drug, has good absorption but suffers from low solubility and poor bioavailability. To address this, a natural polymer-based matrix of alginate and acacia gum was formulated to enhance dissolution. This study aimed to validate a Ultra High Performance Liquid Chromatography method for analyzing ketoconazole content in micro-dissolution testing of capsule formulations. The method employed a C18 column with a mobile phase of acetonitrile:WFI (0.15% TEA, pH 3.5; 50:50) at 1 mL/min and detection at 265 nm. Validation demonstrated compliance with selectivity, linearity (r = 0.9996), sensitivity (LoD 6.51 µg/mL; LoQ 19.74 µg/mL), accuracy (99.6–101.3%), and precision (<2%, except one interday result at 2.08%). Micro-dissolution testing showed sustained ketoconazole release, exceeding 100% within 240 minutes. Data modeling (performed using DDSolver) indicated comparable fit for the Higuchi (R²_adj = 0.96) and Korsmeyer (R²_adj = 0.93) models, suggesting diffusion-controlled release of ketokonazole. The validated UHPLC method is suitable for micro-dissolution studies, and the alginate-acacia gum formulation effectively modulates drug release.
Riview Literatur : Aktivitas Daun Yakon (Smallanthus Sonchifolus) Sebagai Antibakteri Terhadap Staphylococcus Aureus Lutfi Chabib; Arba Pramundita; Prima Aulia Putra; Hady Anshory
Jurnal Ners Vol. 9 No. 2 (2025): APRIL 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v9i2.44403

Abstract

Kulit merupakan organ tubuh terluas yang menutupi seluruh bagian tubuh dan memiliki peran penting untuk melindungi organ tubuh. Posisi kulit terluar menyebabkan kulit rentan terkena penyakit kulit dan terjadi infeksi. Mayoritas infeksi kulit disebabkan oleh bakteri Staphylococcus aureus (S.aureus), yaitu bakteri gram positif yang dapat menyerang kekebalan tubuh. Salah satu cara untuk membunuh bakteri adalah menggunakan zat yang mengandung antibakteri. Salah satu tanaman yang berpotensi menjadi antibakteri adalah Yakon (Smallanthus sonchifolius). Skrining fitokimia menunjukkan bahwa daun yakon memiliki kandungan flavonoid, alkaloid, tanin, saponin, dan steroid yang berfungsi sebagai antibakteri. Senyawa lain yaitu seskuiterpen lakton juga ditemukan pada daun yakon dan memiliki aktivias antibakteri. Penggunaan ekstrak daun yakon pada konsentrasi 15% menghasilkan aktivitas antibakteri yang sangat kuat. Metodologi yang digunakan dalam tinjauan jurnal ini adalah tinjauan naratif, yang melibatkan pemeriksaan ekstensif literatur nasional dan internasional. Temuan pustaka menunjukkan bahwa daun yakon memiliki sifat antibakteri dan menghasilkan zona hambat terhadap bakteri Staphylococcus aureus (S.aureus).
Analytical Method Validation of High Performance Liquid Chromatography for Ketoconazole Tablets Lumakso, Fajar Aji; Annisa, Viviane; Alviansyah, Muhammad Rizal; Chabib, Lutfi
Indonesian Journal of Pharmaceutical Science and Technology Vol 13, No 1 (2026)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v13i1.69415

Abstract

Ketoconazole is an azole antifungal with low solubility and classified as Biopharmaceutical Classification System (BCS) Class II. A tablet formulation based on an alginate-acacia gum matrix is developed to enhance the solubility of ketoconazole. This study aims to validate the analytical method using High-Performance Liquid Chromatography (HPLC) for the assay of ketoconazole in these tablet formulations. The analysis was performed using a C18 column (250×4.6 mm, 5 μm) with a mobile phase consisting of water for injection (WFI) containing 0.15% TEA (pH 3.3) and acetonitrile (50:50 v/v), flow rate 1.0 mL/min, and detection at 232 nm. Method validation included system suitability testing, linearity, accuracy, precision, specificity, LOD, and LOQ. Specificity testing indicated no interference at the retention time of ketoconazole. Good linearity was achieved over 10–250 ppm (r = 0.9996), with good accuracy (99.8–101.75%) and precision (intraday and interday; %RSD < 2%). LOD and LOQ were 2.357 ppm and 7.142 ppm, respectively. The developed HPLC method was shown to be valid, accurate, precise, selective, and reliable for the assay of ketoconazole in tablets formulated with an alginate-acacia gum matrix. This method can be used for routine quality control.
Pengaruh Variasi Bahan Penghancur terhadap Sifat Fisikokimia dan Disolusi Tablet Aminofilin sebagai Terapi Asma Taufikurrahmi Taufikurrahmi; Hani’atul Kharimah; Hanida Destriana Fatmawati; Syarif Hidayatullah; Lutfi Chabib
Journal of Pharmascience Vol. 4 No. 1 (2017): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v4i1.5759

Abstract

ABSTRAK Pembuatan tablet Aminofilin menggunakan metode granulasi basah dikarenakan memiliki sifat alir dan kompaktibilitas yang kurang baik. Granulasi basah memerlukan bahan penghancur agar formula tablet sangat berlawanan dengan fungsi bahan pengikat. semakin kuat daya ikat bahan pengikat maka dipilih bahan penghancur dengan daya hancur yang semakin besar. Konsentrasi dari bahan penghancur akan mempengaruhi kecepatan disintegrasi. Tujuan dari penelitian adalah untuk mengetahui pengaruh dari konsentrasi bahan penghancur yaitu primojel yang digunakan terhadap kualitas tablet aminophilin yang dihasilkan. Pada penelitian akan dibuat sediaan tablet aminofilin dengan variasi bahan penghancur yaitu primojel. Dilakukan evaluasi granul seperti uji sifat alir serta evaluasi tablet seperti keseragaman bobot, ukuran, kandungan, kekerasan, kerapuhan, waktu hancur dan disolusi. Hasil yang diperoleh dari penelitian ini dapat disimpulkan bahwa formula tablet yang mengandung bahan penghancur pada formula I, formula II, Formula III menghasilkan tablet yang memenuhi persyaratan tablet yang baik. Kata Kunci: Aminofilin, Granulasi Basah, Variasi Primojel ABSTRAK Aminophylline tablet manufacturing using wet granulation method due to having flow properties and compactibility unfavorable. Wet granulation requires a shredder material that tablet formula is in contrast with the function of the binder. The stronger the power tie then selected binder material crushers with crushed greater power. The concentration of disintegrant will affect the speed of disintegration. The purpose of the study was to determine the effect of the concentration of primojel crushers are used to the quality of the resulting tablet aminophylline. The research will be made with a variety of aminophylline tablet dosage shredder material that is primojel. Test to evaluate the granules as flow properties and evaluation of tablets such as uniformity of weight, size, content, hardness, friability, disintegration time and dissolution. The results obtained from this study can be concluded that the formula tablets containing material crusher of formula I, Formula II, Formula III to produce a tablet that meets the requirements of a good tablet. Keywords: Aminophylline, Wet Granulation, Variation Primojel
Tanaman dengan Aktivitas Anti-Asma Muhammad Ikhwan Rizki; Lutfi Chabib; Akhmad Nabil; Baharudin Yusuf
Journal of Pharmascience Vol. 2 No. 1 (2015): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v2i1.5807

Abstract

Abstrak            Asma merupakan gangguan inflamasi kronis pada saluran pernafasan ditandai episode berulang mengi, sesak nafas, sesak dada, dan batuk.  Berbagai sel inflamasi berperan terutama sel mast, eosinofil, sel limfosit T, makrofag, neutrofil dan sel epitel. Masyarakat di Indonesia turun temurun secara tradisional menggunakan bahan alam dalam mengatasi berbagai penyakit. Tanaman dapat menghasilkan metabolit sekunder yang memiliki banyak khasiat dalam mengatasi berbagai penyakit disebabkan adanya efek sinergisme antar senyawa metabolit sekunder dan polivalent activity, sehingga memungkinkan mengatasi berbagai penyakit. Berdasarkan hal tersebut, asma dapat diatasi dengan menggunakan bahan alam diantaranya Putri Malu (Mimosa pudica, Linn.), Kelor (Moringa oleifera), Jintan Hitam (Nigella sativa L.), Rumput Fatimah (Labisia pumila), Ciplukan (Physalis minima L), Senggugu (Clerodendrum  serratumat), Jeringau (Acorus gramineus), dan Sirih (Piper betle Linn.). Kata Kunci: Tanaman, Anti-Asma AbstractAsthma is a chronic inflammatory disorder of the airways characterized by recurrent episodes of wheezing, breathlessness, chest tightness, and coughing. Various inflammatory cells play a role, especially mast cells, eosinophils, T lymphocytes, macrophages, neutrophils and epithelial cells. Indonesia people used natural materials to overcome various diseases. Plants can produce secondary metabolites that have many benefits in addressing a variety of diseases caused by the synergism between the effects of secondary metabolites and polivalent activity, making it possible to overcome various diseases. Based on this, asthma can be overcome by using natural medicines including Putri Malu (Mimosa pudica, Linn.), Kelor (Moringa oleifera), Jintan Hitam (Nigella sativa L.), Rumput Fatimah (Labisia pumila), Ciplukan (Physalis minima L), Senggugu (Clerodendrum  serratumat), Jeringau (Acorus gramineus), Sirih (Piper betle Linn.) Keywords: Asthma, Plants
Formulasi Tablet Effervescent Ekstrak Lidah Buaya (Aloe vera) Lutfi Chabib; Oktavia Indrati; Muhammad Ikhwan Rizki
Journal of Pharmascience Vol. 2 No. 1 (2015): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v2i1.5816

Abstract

Abstrak            Lidah buaya (Aloe vera) mengandung komponen seperti  acetylated mannans, polymannans, anthraquinone C-glycosides, anthrones, anthraquinones dan  berbagai jenis lectins. Komponen dalam lidah buaya yang bermanfaat sebagai laksatif adalah anthraquinon glycoside. Salah satu sediaan farmasi yang menarik adalah tablet effervescent, dimana bentuk sediaan ini mempunyai beberapa keuntungan, diantaranya adalah mudah untuk dikonsumsi dan bisa dikembangkan variasi rasa, sehingga diharapkan masyarakat dapat tertarik untuk mengkonsumsi sediaan lidah buaya dalam bentuk tablet effervescent. Tujuan penelitian ini yaitu mendapat formulasi optimum dari  tablet effervescent ekstrak lidah buaya. Lidah buaya dihaluskan lalu dimaserasi. Ekstrak lidah buaya diformulasi dalam empat bentuk formula yang berbeda dengan metode peleburan. Dilakukan pemeriksaan sifat fisik granul dan tablet yang terbentuk. Hasil penelitian menunjukkan lidah buaya (Aloe vera) dapat diformulasikan kedalam sediaan tablet  effervescent. Dari data evaluasi formulasi sediaan tablet effervescent lidah buaya (Aloe vera) yang paling baik untuk dibuat tablet effervescent yaitu formula I yang berisi granul ekstrak 150 mg, laktosa 1890 mg, asam sitrat 100 mg, asam tartat 300 mg, natrium bikarbonat 400 mg, PEG 6000 60 mg, aspartame 100 mg, dan pengaroma secukupnya. Kata Kunci: Aloe vera, tablet effervescent, formulasi AbstractAloe vera containing components such as acetylated mannans, polymannans, anthraquinone C-glycosides, anthrones, anthraquinones and various types of lectins. Components in aloe vera useful as laksatife is anthraquinon glycoside. One of the interesting pharmaceutical preparations is effervescent tablets, where has several advantages, is easy to take the variation flavors, so hopefully people can be interested to consume aloe vera preparations in the form of effervescent tablets. The purpose of this study was to get optimum formulation of Aloe vera effervescent tablets. Aloe vera is pulverized and then macerated. Aloe vera extract was formulated in six different formulas with fusion method. Then, physical properties of the granules and tablets were examinated. Results showed aloe (Aloe vera) could be formulated into effervescent tablets. The best formula for Aloe vera effervescent tablets was formula I which containing 150 mg of granule extract 150 mg, 1890 mg of lactose, 100 mg of citric acid, 300 mg of tartat acid, 400 mg of sodium bicarbonate, 60 mg of PEG 6000, 100 mg of aspartame, and flavor to taste. Keywords: Aloe vera, effervescent tablets, formulation  
Review Rheumatoid Arthritis: Terapi Farmakologi, Potensi Kurkumin dan Analognya, serta Pengembangan Sistem Nanopartikel Lutfi Chabib; Zullies Ikawati; Ronny Martien; Hilda Ismail
Journal of Pharmascience Vol. 3 No. 1 (2016): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v3i1.5830

Abstract

 ABSTRAK  Rheumatoid arthritis  (RA) adalah  penyakit  autoimun  yang menyebabkan  peradangan  kronis  pada sendi. Penatalaksanaan RA harus agresif dan sedini mungkin sehingga mampu meningkatkan hasil jangka pendek maupun panjang penderita. Rheumatoid arthritis akibat reaksi autoimun dalam jaringan sinovial yang melibatkan proses fagositosis. Tujuan dari pengobatan rheumatoid arthritis tidak hanya mengontrol gejala penyakit, tetapi juga penekanan aktivitas penyakit untuk mencegah kerusakan permanen. Penderita RA memulai pengobatan mereka dengan DMARDs (Disease Modifying Anti-Rheumatic Drugs) seperti metotreksat, sulfasalazin dan leflunomid. Alternatif pengobatan yang dapat dijadikan salah satu pilihan dalam penanganan RA yaitu senyawa kurkumin dan analognya. Sistem nanopartikel mampu meningkatan efektifitas dalam pengobatan terutama keadaan RA. Kata kunci : rheumatoid arthritis, Disease Modifying Anti-Rheumatic Drugs, kurkumin, nanopartikel. ABSTRACT Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic inflammation of the joints. Management of RA must be aggressive and as early as possible so as to increase the yield of short and long term patients. Rheumatoid arthritis due to an autoimmune reaction in the synovial tissue that involves the process of phagocytosis. The purpose of the treatment of rheumatoid arthritis not only control the symptoms of the disease, but also suppressed disease activity to prevent permanent damage. RA patients begin their treatment with DMARDs (Disease Modifying Anti-Rheumatic Drugs) such as methotrexate, sulfasalazine and leflunomid. Alternative treatments that can be used as an option in the treatment of RA are compounds curcumin and its analogs. Nanoparticle systems is able to increase the effectiveness in the treatment of RA, especially state. Keywords: rheumatoid arthritis, Disease Modifying Anti-Rheumatic Drugs, curcumin, nanoparticles.
Pengujian Toksisitas Seluler SNEDDS Ekstrak Daun Kangkung (Ipomoea reptans, Poir) Terstandar Lutfi Chabib; Farida Hayati; Rizki Awaluddin; Muh Iqbal Pangestu
Journal of Pharmascience Vol. 6 No. 2 (2019): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v6i2.7350

Abstract

ABSTRAK Kangkung darat (Ipomea reptans Poir) adalah salah satu tanaman di Indonesia yang secara empiris telah dimanfaatkan oleh masyarakat sebagai obat untuk terapi Diabetes Melitus (DM).  Riset sebelumnya telah dilakukan untuk memperoleh data ilmiah dari pemanfaatan kangkung darat sebagai terapi DM, dan pengembangannya dalam bentuk sediaan Self Nano Emulsifying Drug Delivery System (SNEDDS). Penelitian ini bertujuan untuk mengetahui sitotoksisitas sediaan SNEDDS ekstrak daun kangkung terstandar dengan menggunakan metode MTT (Methyl-Thiazolyl-Tetrazolium). Pengujian MTT dilakukan dengan cara well plate diplotkan terlebih dahulu untuk sampel uji 70 sumuran (well), kontrol sel 6 sumuran, dan kontrol media 6 sumuran.  Terakhir tiap sumuran ditambahkan stopper SDS sebanyak 100µl. Plate dibungkus alumunium foil dan diinkubasi semalaman pada suhu ruang. Hari berikutnya dilakukan pembacaan absorbansi sampel, kontrol media, dan kontrol sel menggunakan ELISA reader. Uji sitotoksik SNEEDS kangkung pada sel vero diperoleh hasil bahwa SNEEDS kangkung tidak menyebabkan kematian pada sel uji. Pada pengujian sel dilakukan pemaparan sampel excipient dari SNEEDS kangkung sebagai pembanding, dengan hasil menyebabkan kematian <50% sel uji pada dua kadar tertinggi dari sampel excipient. Namun pada hasil uji SNEEDS kangkung diperoleh data bahwa toksisitas excipient pada kadar tersebut tidak mempengaruhi timbulnya toksisitas pada sampel SNEEDS kangkung. Sehingga berdasarkan uji in vitro, SNEEDS kangkung tidak toksik terhadap sel vero. Kata kunci: Ipomoea reptans, sitotoksisitas, SNEDDS  ABSTRACT Kangkong (Ipomea reptans Poir) is a type of Indonesian plant empirically utilized by many people to treat diabetes mellitus (DM). A study has been conducted to obtain scientific data from the use of kangkong for DM treatment as well as to develop kangkong in SNEDDS preparation. This current study aimed to examine the cytotoxicity of kangkong leaf standardized extract in SNEDDS preparation through the MTT (Methyl-Thiazolyl-Tetrazolium) method. MTT assay was performed by initially plotting well plates for test sample (70 wells), control cell (6 wells), and control medium (6 wells). As much as 100µl SDS stopper was added into each well, and then plates were wrapped in aluminum foil and incubated all night at ambient temperature. On the following day, the absorbance of test sample, control medium, and control cell was identified using ELISA reader. The cytotoxicity test of kangkong SNEDDS on Vero cell lines showed that kangkong SNEDDS did not cause cell death. The cell was tested through exposure of excipient sample from kangkong SNEDDS as a comparison, resulting in <50% cell death by the two highest concentrations of excipient sample. However, the test result of kangkong SNEDDS indicated that excipient toxicity at such concentrations did not affect kangkong SNEDDS. Therefore, based on in vitro test, kangkong SNEDDS is not toxic against Vero cell lines. Keywords: Ipomoea reptans, cytotoxicity, SNEDDS
Optimization and Physical Characterization of Kojic Acid Nanoemulsion Formula As A Whitening Agent Yovi Guanse; Rini Dwiastuti; Brigita Tuelvin Jenita Gandi; Lutfi Chabib
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 22, No 2 (2025)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.009968

Abstract

Kojic acid (KA) as a topical formulation prevents hyperpigmentation through the inhibition of tyrosinase activity. However, KA has higher solubility in nonpolar solvents. Nanoparticle technology can be a novel innovation to enhance KA absorption into the skin. This study aims to improve the delivery of topically applied KA by enhancing absorption into the stratum corneum by optimizing the concentration of surfactant Tween 80 and co-surfactant Span 80. The nanoemulsion uses KA as an active ingredient and virgin coconut oil as the oil phase. The optimum area was analyzed using Design-Expert® 13 software, with a pure experimental design based on a 2x2 factorial design. The results indicate that all formulas are within the optimal region. Therefore, the determination of the optimal point can be grounded on the smallest composition within the optimal region with the objective of maximizing material efficiency, which is a formula with a concentration of Tween 80 and Span 80 of 10 grams and 3 grams, respectively. The particles are a spherical smooth shape and demonstrate an efficacy of 94.117% in inhibiting tyrosinase activity.
Co-Authors Abdul Hakim Agenilia Permatasari Aghna Mafruha Zahrah, Aghna Mafruha Agus Santosa Aji Winanta Akhmad Fauzy Akhmad Fauzy Akhmad Nabil Akhmad Nabil, Akhmad Alviansyah, Muhammad Rizal Anggara Setyabawana Putra, Anggara Setyabawana Aprianto . Aprianto Aprianto Arba Pramundita Arba Pramundita Ramadani Arif Arismunandar Arifa Caryn Dea Utami Hasyono Arman Suryani Artha Carolina Ashfiya, Salwa Asih Triastuti Awaluddin, Rizki Baharuddin Yusuf Baharudin Yusuf Bambang Subekti Baruna, Renno Ramadhani Ika Brigita Tuelvin Jenita Gandi Cermenda, Riska Cynthia Astiti Putri Deviami, Natasya Aulia Dian Martines, Luh Ade Dimas Adhi Pradana Dzihni Meytasari Ezatul Ezleen Kamarulzaman Farah Deastasa Nabilah Febry Azizah Ferdy Firmansyah Gandhi Barajana Vedha Hady Anshory Hamzah, Hasyrul Hani’atul Kharimah Hanida Destriana Fatmawati Hani’atul Kharimah Hannie Fitriani Hasnaeni hasnaeni, Hasnaeni Hastri Kholifah Hayati, Farida Herman Felani Hilda Ismail, Hilda Ilham Syahbandi Ipaenin, Jahiria Kholidah, Ziyyatul Lumakso, Fajar Aji M. Pandoman febrian Martien, Ronny Maulana Ardhi Mimiek Murrukmihadi Mufrod Mufrod Muh Iqbal Pangestu Muhammad Ikhwan Rizki Muhammad Iqbal Pangestu Muhtadi, Wildan Khairi Muslim, M. Rifqi Fadillah Mutiara Herawati, Mutiara Muzakir, Mellisa Nurul Afifi Lobubun Oktavia Indrati, Oktavia Prima Aulia Putra Reihan Khairiati Renno Ramadhani Ika Baruna Ria Cahya Andriana Rickha Octavia Rini Dwiastuti Rischi Dwi Irianti Rischi Dwi Irianti, Rischi Dwi Rizqi, Syifa Maulidia Rochmy Istikharah Ronny Martien Ronny Martien Safarullah, Muhammad Samsul Hadi Saskira Windy Siti Zahliyatul Munawiroh Syarif Hidayatullah Taufikurrahmi Taufikurrahmi Tengku Shella Trianloka, A. M. Bagas Tunny, Risman Uzulul Hikmah Viviane Annisa Wahyu, Imron Wistiqomah Indasari Yandi Syukri Yosi Febrianti, Yosi Yovi Guanse Ziyyatul Kholidah