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All Journal Perspektif : Review Penelitian Tanaman Industri Elkawnie Majalah Obat Tradisional Dentino: Jurnal Kedokteran Gigi Pharmascience Journal of Islamic Pharmacy JPSCR : Journal of Pharmaceutical Science and Clinical Research Abditani : Jurnal Pengabdian Masyarakat SRIWIJAYA JOURNAL OF MEDICINE Medika Kartika : Jurnal Kedokteran dan Kesehatan Perspektif, Review Penelitian Tanaman Industri AJAD : Jurnal Pengabdian kepada Masyarakat Proceeding of Mulawarman Pharmaceuticals Conferences Medical Sains : Jurnal Ilmiah Kefarmasian Journal of Applied Agricultural Science and Technology Room of Civil Society Development Riset Informasi Kesehatan AGRIC kawanad Kartika : Jurnal Ilmiah Farmasi Medical Sains : Jurnal Ilmiah Kefarmasian Room of Civil Social Development Agroscript: Journal of Applied Agricultural Sciences
Fahrauk Faramayuda, Fahrauk
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Aerospace Engineering Agriculture, Biological Sciences & Forestry Arts Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Control & Systems Engineering Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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REVIEW: PLANTS WITH REPELLENT ACTIVITY Purnama, Uwan; Faramayuda, Fahrauk
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 4 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i4.1174

Abstract

Mosquitoes are vectors of illnesses, such as encephalitis, dengue, filariasis, intestinal sickness, and encephalitis. These diseases have become epidemics in Indonesia and around the world. Natural repellents are alternatives for preventing mosquito-borne diseases that are safe, easily degradable, and eco-friendly. This review aimed to identify compounds in plants with mosquito repellent activity. Data were obtained from national and international journals using search platforms, including PubMed, Scholar, SciDirect, and Hindawi. This review focuses on plants with repellent activity, their resulting repellent activity, the content of bioactive compounds, and the mosquito species used. Many plants contain naturally occurring compounds that can repel mosquitoes. Following scientific research, 14 bioactive compounds have been shown to have repellent activity in plants. Keywords: repellent, volatile oil, mosquitos, bioactive compounds, narrative literature review
ANTIOXIDANT ACTIVITY OF COMBINATION OF WHITE-PURPLE Orthosiphon aristatus (Blume) Miq HERB EXTRACT AND Stevia rebaudiana Bertoni USING FRAP METHOD Faramayuda, Fahrauk; Syam, Akhirul Kahfi; Putri, Dhiffa Namira Alifia; Ismail, Nursafira Khairunnisa; Akbar, Tzazkia Febriyana; Farhan
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 10 No 2 (2025)
Publisher : Universitas Muhammadiyah Ahmad Dahlan Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v10i2.1612

Abstract

Oxidative stress is caused by an increase or decrease in the antioxidant defense activity. Orthosiphon aristatus (Blume) Miq and Stevia are two plants that contain antioxidant compounds and can bind free radical compounds. The combination of Orthosiphon aristatus (Blume) Miq and Stevia was expected to increase antioxidant activity. This study aimed to determine the antioxidant activity of a combination of the Orthosiphon aristatus (Blume) Miq white-purple variety and Stevia rebaudiana Bertoni extract. Antioxidant activity was tested using the FRAP method with a UV-visible spectrophotometer at a wavelength of 710 nm. The results of phytochemical screening showed that both plant extracts and dry material contained secondary metabolite compounds, including flavonoids, polyphenols, saponins, quinones, steroid-triterpenoids, and monoterpenes-sesquiterpenes. A qualitative test relating to antioxidants using TLC showed positive antioxidant activity, which was proven by the presence of green or blue light on the TLC plates. This was due to electron transfer in the compound, which reduced Fe3+ to Fe2+. On the other hand, quantitative measurements using the FRAP method showed the antioxidant capacity values consecutively, F1 combination extract (1:1) of 43.725 mg of QE/g extract, F2 combination extract (2:1) of 57.963 mg of QE/g extract, and combination extract of F3 (3:1) of 64.849 mg of QE/g extract. The extract combination of F3 showed the best formula, with a value of 64.849 mg QE/g extract.  Keywords: Orthosiphon aristatus (Blume) Miq, Stevia, antioxidants, FRAP
Pelatihan Pembuatan Serbuk Jamu Instan sebagai Model Pemberdayaan UMKM di Kota Cimahi Faramayuda, Fahrauk; Windyaswari, Ari Sri
Room of Civil Society Development Vol. 4 No. 4 (2025): Room of Civil Society Development
Publisher : Lembaga Riset dan Inovasi Masyarakat Madani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59110/rcsd.734

Abstract

Banyak pelaku usaha jamu di Indonesia menghadapi kendala dalam meningkatkan kualitas produk akibat keterbatasan keterampilan teknis dan pengetahuan pengolahan tanaman obat. Kegiatan pengabdian ini bertujuan untuk meningkatkan pengetahuan dan keterampilan komunitas usaha jamu di Kota Cimahi melalui pelatihan pembuatan serbuk instan. Metode pelaksanaan meliputi penyuluhan, praktik langsung, serta evaluasi melalui pre-test dan post-test yang diikuti oleh 37 peserta. Analisis data dilakukan dengan membandingkan rata-rata skor pre-test dan post-test, disertai dokumentasi lapangan. Hasil menunjukkan adanya peningkatan rata-rata skor dari 6,05 menjadi 6,41 atau sebesar 5,8%. Peserta juga berhasil menghasilkan produk serbuk instan berbahan jahe, kunyit, dan beras kencur, yang sebagian telah memperoleh izin edar sederhana berupa SPP-IRT. Selain itu, pelatihan berdampak pada peningkatan kapasitas produksi mitra serta kepercayaan diri peserta dalam memasarkan produk. Dengan demikian, pelatihan ini dapat dipandang sebagai model intervensi awal yang efektif untuk memperkuat daya saing UMKM jamu lokal, yang keberlanjutannya memerlukan dukungan pendampingan dan strategi pemasaran modern.
Sosialisasi Penanganan Pasca Panen Bahan Baku Rempah Obat Tradisional Faramayuda, Fahrauk; Riyanti, Soraya; Syam, Akhirul Kahfi; Windyaswari, Ari Sri; Karlina, Yeni; Limbong, Remare Halomoan; Fitrichia, Anggita Esa Putri; Pertiwi, Ananda Tunjung; Aprilia, Trialisa; Mutya, Ema; Dewi, Renti Mutiara; Pratiwi, Dwi Ayu; Septiani, Usi; Amedea, Esanda Zulfi; Wulandari, Yesi; Fitriani, Adinda; Dwigantina, Ami Soega
Kawanad : Jurnal Pengabdian kepada Masyarakat Vol. 1 No. 2 (2022): October
Publisher : Yayasan Kawanad

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56347/kjpkm.v1i2.52

Abstract

Community service activities carried out by students of Universitas Jenderal Achmad Yani were carried out on August 29, 2022, taking place in a medicinal plant garden, Faculty of Pharmacy, Universitas Jenderal Achmad Yani which was attended by UMKM Spice Nusantara Bandung participants. The socialization carried out was the presentation and delivery of post-harvest processing materials (wet sorting, washing, drying, and dry sorting) and the standardization of traditional raw materials. Conventional medicine is a form of treatment efforts in the community to support health which is currently being recommended by the government. Communities can use the toga as an economical and efficient measure to maintain body immunity because the community can obtain and use the toga quickly and simply to maintain family health. The postharvest process greatly determines the existence of active compounds that are efficacious for treatment. Incorrect postharvest management can change, reduce, or destroy the active substance of a plant into a substance that has no therapeutic effect and can even endanger health. The results of the participant's level of understanding were carried out post-test with the results of what is the purpose of post-harvest processing (100%), the sequence of post-harvest processing (80%), what is the general drying temperature (100%), a medicinal plant has good quality and efficacy then we need to know (80%), and what is the function of the washing process (90%) with the conclusion that socialization activities can significantly increase the knowledge of participants from MSMEs regarding planting, post-harvest processing, and the properties of medicinal plants significantly.
Pelatihan Pembuatan Serbuk Jamu Instan sebagai Model Pemberdayaan UMKM di Kota Cimahi Faramayuda, Fahrauk; Windyaswari, Ari Sri
Room of Civil Society Development Vol. 4 No. 4 (2025): Room of Civil Society Development
Publisher : Lembaga Riset dan Inovasi Masyarakat Madani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59110/rcsd.734

Abstract

Banyak pelaku usaha jamu di Indonesia menghadapi kendala dalam meningkatkan kualitas produk akibat keterbatasan keterampilan teknis dan pengetahuan pengolahan tanaman obat. Kegiatan pengabdian ini bertujuan untuk meningkatkan pengetahuan dan keterampilan komunitas usaha jamu di Kota Cimahi melalui pelatihan pembuatan serbuk instan. Metode pelaksanaan meliputi penyuluhan, praktik langsung, serta evaluasi melalui pre-test dan post-test yang diikuti oleh 37 peserta. Analisis data dilakukan dengan membandingkan rata-rata skor pre-test dan post-test, disertai dokumentasi lapangan. Hasil menunjukkan adanya peningkatan rata-rata skor dari 6,05 menjadi 6,41 atau sebesar 5,8%. Peserta juga berhasil menghasilkan produk serbuk instan berbahan jahe, kunyit, dan beras kencur, yang sebagian telah memperoleh izin edar sederhana berupa SPP-IRT. Selain itu, pelatihan berdampak pada peningkatan kapasitas produksi mitra serta kepercayaan diri peserta dalam memasarkan produk. Dengan demikian, pelatihan ini dapat dipandang sebagai model intervensi awal yang efektif untuk memperkuat daya saing UMKM jamu lokal, yang keberlanjutannya memerlukan dukungan pendampingan dan strategi pemasaran modern.
Enhancing Nutraceutical Properties of Moringa: A Biotechnological Perspective Faramayuda, Fahrauk; Riyanti, Soraya; Adely, Alyaa Muliahati
Sriwijaya Journal of Medicine Vol. 8 No. 3 (2025): Vol 8, No 3, 2025 (Issue In Progress)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjm.v8i3.347

Abstract

Moringa oleifera Lam. is recognized for its versatile nutritional and medicinal benefits, largely attributed to its rich polyphenolic content, which includes bioactive compounds with significant antioxidant, anticancer, antimicrobial, and antidiabetic properties. This study addresses the gap in knowledge regarding the enhancement of phenolic compounds in Moringa leaves through innovative biotechnological methods. The primary objective is to analyze the extraction and quantification of polyphenols from Moringa leaves subjected to boiling and fermentation processes to produce kombucha. Using the Folin-Ciocalteu method, quantified the total polyphenol content, revealing that boiled Moringa leaves contained 67.66 ± 2.79 mg/g of polyphenols, while the resulting kombucha tea exhibited a higher concentration at 70.66 ± 2.79 mg/g. These findings demonstrate the potential of Moringa leaves as not only a dietary supplement but also as a functional ingredient in health-promoting beverages, such as kombucha. The implications extend to enhancing the nutritional value of plant-based diets and establishing Moringa as a sustainable antioxidant source. This research underscores the importance of advanced biotechnological approaches in optimizing extraction and cultivation methods, thus potentially increasing phenolic yields. By providing crucial insights into the functional applications of Moringa leaves, this study contributes to the broader fields of plant biotechnology and food science, encouraging further exploration into their health benefits and utility in promoting sustainable nutrition.
Comparative Assessment of Antioxidant Properties Between In-Vitro Cultured Cat's Whiskers Leaves (Orthosiphon stamineus) and Quercetin Faramayuda, Fahrauk; Choirunnisa, Dinda; Karlina, Yenni
Journal of Applied Agricultural Science and Technology Vol. 9 No. 4 (2025): Journal of Applied Agricultural Science and Technology
Publisher : Green Engineering Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55043/jaast.v9i4.479

Abstract

The present study investigates the antioxidant properties of in-vitro cultured leaves of cat's whiskers (Orthosiphon stamineus) compared to the well-known antioxidant quercetin. Antioxidants are crucial for neutralizing free radicals and play a significant role in protecting cells from oxidative stress, a contributing factor to various diseases and aging processes. The research aims to quantify and compare the radical scavenging activity of extracts from the in vitro cultured leaves and quercetin, using the DPPH method, a widely recognized assay in antioxidant research. Extraction involved macerating in-vitro cultured cat's whiskers leaves with 96% ethanol, which facilitates the dissolution of active phytochemicals. Antioxidant activity was subsequently assessed through the DPPH assay, where colorimetric change indicates the extract’s scavenging ability towards free radicals. The findings revealed that the in vitro cultured leaves extract exhibited a potent antioxidant activity, with an IC50 value of 0.74 μg/mL, significantly lower than quercetin’s IC50 value of 7.51 μg/mL. These results highlight the potential of in-vitro cultured cat's whiskers as a natural antioxidant source, suggesting possible applications in the food and pharmaceutical industries, where combating oxidative stress is essential for health maintenance and disease prevention. Further research is necessary to elucidate the specific biochemical pathways and mechanisms underpinning the antioxidant capacity of the in vitro cultured leaves extracts.
Comparative Efficacy of Phaseolus aureus Extract and Synthetic Growth Regulators on Callus Induction in Curcuma xanthorrhiza Faramayuda, Fahrauk; Melani, Putri Dwi; Elfahmi, Elfahmi
AGROSCRIPT: Journal of Applied Agricultural Sciences Vol 7 No 2 (2025): December
Publisher : Universitas Perjuangan Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36423/agroscript.v7i2.2392

Abstract

Temulawak (Curcuma xanthorrhiza Roxb) a plant indigenous to Indonesia, is increasingly recognized for its medicinal properties, formulating a cornerstone of traditional medicine with annual usage marking a significant growth rate of approximately 5.4%. As awareness of its therapeutic potential expands, too does the demand for this valuable resource, necessitating enhanced efforts in its propagation and the extraction of its bioactive compounds. This study investigates the efficacy of different growth regulators in the induction of callus tissue from C. xanthorrhiza through plant tissue culture, a key method for regenerating valuable plant material. Specifically, the research focuses on the comparative effects of natural growth regulators, particularly water extracts from Phaseolus aureus, and synthetic growth regulators such as 2,4-Dichlorophenoxyacetic Acid (2,4-D) and Indole-3-butyric Acid (IBA) in varied concentrations. The experimental design included varying concentrations of P. aureus water extract at 10%, and 15%, alongside a fixed concentration of the synthetic agents. Findings indicated that synthetic growth regulators, particularly the combination of 2,4-D and IBA at a concentration of 0.4 ppm each, yielded superior callus proliferation compared to the natural extract treatments. However, P. aureus aqueous extract showed positive effects also on callus emergence and on increasing explant size when used at 10% concentration in Murashige-Skoog medium. Consequently, the study underscores the potential of integrating both natural and synthetic growth regulators to enhance callus induction and ultimately facilitate the sustainable use of C. xanthorrhiza as a medicinal resource.
Co-Authors Adella Shindy Pratiwi Adely, Alyaa Muliahati Adinda Fitriani Adriana, Reyhan Akbar, Tzazkia Febriyana Akhirul Kahfi Syam Amedea, Esanda Zulfi Ami Soega Dwigantina Ananda Tunjung Pertiwi Anggita Esa Putri Fitrichia Aprilia, Trialisa Ari Sr Windyaswari Ari Sri Widyaswari Ari Sri Windyaswari Ari Sri Windyaswari Ari Sri Windyaswari, Ari Sri Ayu, Inna Puspa Chandani Nurul Hafizah Choirunnisa, Dinda dessy ratnasari Dewi, Renti Mutiara Dhimas Ariya Wibiksana Dwi Ayu Pratiwi Dwigantina, Ami Soega Dyah Nur Azizah, Dyah Nur Elfahmi Elfahmi Elfahmi Elfahmi, Elfahmi Ema Mutya Endang Kumolowati Esanda Zulfi Amedea Euis Reni Yuslianti Faizal Hermanto Farhan Fikri Alatas Fitriani, Adinda Fitrichia, Anggita Esa Putri Iis Inayati Rakhmat Ismail, Nursafira Khairunnisa Jaka Permana Jovie Mien Dumanauw Julia Ratnawati Julia Ratnawati Khairunisa Harizqi Nurul Husna Limbong, Remare Halomoan Melani, Putri Dwi Muhamad Raihan Maulana Muhammad Irwan Mutya, Ema Niken Tunjung Murti Pratiwi Nira Purnamasari, Nira Nur Achsan Al-Hakim Nur Fauziyyah, Salma Alifia Nurhalizah, Dinda Siti Nurhayati, Viola Aditya Nursafira Khairunnisa Ismail Oktiyas Muzaky Luthfi Oktovia El Shara Paramita, Veronika Santi Pertiwi, Ananda Tunjung Pratiwi, Dwi Ayu Purnama, Uwan Purwoko, Agus Putri, Dhiffa Namira Alifia Ramelan, Riska Sigit Remare Halomoan Limbong Renti Mutiara Dewi Reyhan Adriana Deris Ridwan Ilyas Ridzka Magfirah Rifaz Muhammad Sukma Riska Sigit Ramelan Rizka Khoirunnisa Guntina Rizka Khoirunnisa Guntina Septiani, Usi Sigid Pamungkas Wicaksono Silvy Julian Siti Muslichah Soraya Riyanti Soraya Riyanti Soraya Riyanti, Soraya Sufyan Zainul Arifin Sugiyanto Sukrasno Sukrasno Sukrasno Sukrasno Sukrasno Sukrasno Sultan Salahudin Jamal SURYANI Suwidjiyo Pramono Totik Sri Mariani Totik Sri Mariani Totik Sri Mariani Totik Sri Mariani Tresa Tri Rayani Tresa Tri Rayani, Tresa Tri Trialisa Aprilia Tzazkia Febriyana Akbar Usi Septiani Viola Aditya Nurhayati Weni Widy Astuti Winda Nur Halimah Wulandari, Yesi Yeni Karlina Yeni Karlina Yeni Karlina, Yeni Yenni Karlina, Yenni Yesi Desmiaty, Yesi Yesi Wulandari Yuslianti, Euis Reni Zaini Alfahmi