Article Per Year (5 Year)
p-Index From 2021 - 2026
8.182
P-Index
This Author published in this journals
All Journal Pharmauho: Jurnal Farmasi, Sains, dan Kesehatan AMALIAH: JURNAL PENGABDIAN KEPADA MASYARAKAT JURNAL FARMASIMED (JFM) PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Riset Kefarmasian Indonesia Community Development Journal: Jurnal Pengabdian Masyarakat Madaniya Indonesian Journal of Chemical Science and Technology Jurnal Farmasi dan Sains Indonesia (JFSI) International Journal of Community Service Jurnal Pengabdian Masyarakat (ABDIRA) International Journal of Health and Pharmaceutical (IJHP) Jurnal Farmasi Klinik dan Sains Jurnal Pengabdian West Science FARMASAINKES Journal of Pharmaceutical and Sciences. Jurnal Pengabdian Masyarakat dan Riset Pendidikan E-Amal: Jurnal Pengabdian Kepada Masyarakat
Yayuk Putri Rahayu
Department Of Pharmacy, Universitas Muslim Nusantara Al Washliyah
Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Energy Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

Published : 66 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 66 Documents
Search

 3   4   5   6   7 
Bioautographic Analysis And Antibacterial Activity Test Of Curry Leaf (Murraya Koenigii (L) Spreng) Ethanol Extract On The Bacteria Propionibacterium Acnes Muhammad Wahyu Ikhsan Muhammad Wahyu Ikhsan; Haris Munandar Nasution; Yayuk Putri Rahayu; M. Pandapotan Nasution
International Journal of Health and Pharmaceutical (IJHP) Vol. 3 No. 1 (2022): February 2023
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (390.65 KB) | DOI: 10.51601/ijhp.v3i1.130

Abstract

Curry leaf (Murraya koenigii (L) Spreng) is one of the plants known to have antibacterial compounds. Curry leaves are also known as temurui leaves and are useful as a natural food flavoring. Curry leaves contain flavonoid compounds, alkaloids, calcium, zinc, riboflavin, folic acid. This study aimed to analyze the bioautography and antibacterial activity of ethanol extract of curry leaves against Propionibacterium acnes bacteria. The research method was carried out experimentally. Curry leaf simplicia extract was made with 96% ethanol as solvent. Curry leaf ethanol extract was made in various concentrations, namely 30%, 40% and 50%. The positive control used was Tetracycline HCl and the negative control was DMSO. The tests carried out on curry leaf simplicia included phytochemical screening, macroscopic examination, microscopic examination, water content examination, examination of water soluble extract content, examination of ethanol soluble extract content, examination of ash content and examination of acid insoluble ash content, bioautographic analysis he results of phytochemical screening showed that curry leaves contain secondary metabolites, namely flavonoids, alkaloids, tannins, saponins, steroids/triterpenoids, and glycosides. The results of the antibacterial activity showed that curry leaves could be used as antibacterial because they had strong inhibition at concentrations of 30%, 40% and 50%, namely 10.3 mm, 11.7 mm and 13.6 mm against P. acnes bacteria. The results of bioatuography showed that the Rf value in the clear zone was 0.17 with a ratio of chloroform:n-Hexane (8:2) on the chromatogram spots by spraying 10% FeCl3 positive for flavonoid compounds which were marked in black.
Edukasi dan Sosialisasi Bahaya Cemaran Bakteri Coliform pada Saus Makanan Jajanan Kepada Masyarakat Desa Amplas Kecamatan Percut Sei Tuan Yayuk Putri Rahayu; Sri Wahyuni; Ridwanto Ridwanto; Haris Munandar Nasution
Jurnal Pengabdian Masyarakat (ABDIRA) Vol 6, No 3 (2026): Abdira, Juli
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/abdira.v6i3.2077

Abstract

Sauces are often used in street food. Based on previous research results, many street food sauces were found to be contaminated with Coliform. Objectives: education and socialization of the dangers of Coliform contamination in street food sauces, skills for preventing Coliform contamination in street food sauces and choosing street food sauces according to SNI. Methods: (1) Lecture counseling on the dangers of Coliform contamination in street food sauces, (2) Education on preventing Coliform contamination in street food sauces and examples of choosing street food sauces according to SNI, (3) Discussion. Activity stages: (1) Survey and partner collaboration, (2) Preparation, (3) Socialization and education, (4) Implementation of Appropriate Technology (TTG), and (5) Evaluation. Results: The level of partner knowledge about the dangers of Coliform contamination in street food sauces and how to choose sauces according to SNI standards increased by 78.38% from an average of 4.63 to 8.25. Conclusion: (1) Partners gain knowledge about the dangers of Coliform contamination in snack sauces, (2) Partners gain knowledge and skills in preventing Coliform bacteria contamination in snack sauces and choosing clean and healthy snack sauces according to SNI.
Konsentrasi Hambat Minimum Dan Konsentrasi Bunuh Minimum Ekstrak Etanol Dan Nano Ekstrak Kulit Durian (Durio zibethinus murr) Terhadap Bakteri Staphylococcus epidermidis Tahnia Maulidya; Yayuk Putri Rahayu; Minda Sari Lubis; Haris Munandar Nasution
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 3 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i3.1925

Abstract

Introduction: Durian peel is a source of phytochemicals with antibacterial potential, and particle-size reduction may modify dispersion and measured in vitro activity. This study evaluated the operational minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of ethanol extract and a size-reduced ("nano extract") preparation of durian peel against Staphylococcus epidermidis. Methods: The ethanol extract was prepared by maceration with 96% ethanol; 30 g of the same extract was homogenized at 1,700 rpm for 1 h and ultrasonicated for 1 h. Particle size, phytochemical screening, broth absorbance at 600 nm, qualitative subculture, and disk diffusion were evaluated in triplicate (n=3). Inhibition-zone data were analyzed using one-way ANOVA. Results: The mean particle size was 645.72 nm. Operational MIC values were 6.25% for the ethanol extract and 0.625% for the nano extract, while no growth after subculture was observed at 50% and 5%, respectively. Mean inhibition zones ranged from 6.6-14.5 mm and 8.3-18.3 mm, with significant concentration-related differences within each series (p<0.001). Discussion and conclusion: The size-reduced preparation reached inhibitory endpoints at lower nominal concentrations within its test series. However, final concentrations were not analytically verified, and optical interference and qualitative bactericidal endpoints limit direct inference of intrinsic potency. These findings support in vitro antibacterial activity but do not establish a quantified increase in potency or a reduction in therapeutic dose
UJI AKTIVITAS ANTIBAKTERI NANOPARTIKEL EKSTRAK ETANOL DAUN MATOA (Pometia pinnata J.R. Forst & G. Forst) TERHADAP BAKTERI Streptococcus mutans Nelsa Fahira; Yayuk Putri Rahayu; Haris Munandar Nasution; M Pandapotan Nasution
Jurnal Riset Kefarmasian Indonesia Vol. 5 No. 1 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i1.327

Abstract

Streptococcus mutans is one of the bacteria that plays an important role in the formation of dental caries. One of the plants known to have antibacterial compounds are matoa leaves (Pometia pinnata J.R. Forst & G. Forst) family Sapindaceae. The objective of this research was to determine the antibacterial activity of matoa leaves ethanolic extract nanoparticles is better than matoa leaves ethanolic extract against S. mutans bacteria. The research method was carried out experimentally. Free variables, namely the concentration of matoa leaf ethanol extract (KEDM 25% ; KEDM 50%; and KEDM 75%) and the concentration of nanoparticles of matoa leaf ethanol extract (KNDM 2.5%; KNDM 5%; and KNDM 7.5%). Bound variables are antibacterial activity of ethanol extract and nanoparticles of matoa leaf ethanol extract against S. mutans bacteria. The nanoparticle size of the extract was characterized using a Particle Size Analyzer (PSA). Test of antibacterial activity of ethanol extract and matoa leaf ethanol extract nanoparticles against S. mutans using the diffusion method to Kirby Bauer. The result of the extract nanoparticle size characterization was 324.97 nm. Zone of Inhibition (ZOI) values of antibacterial ethanol extract of matoa leaves against S. mutans were 12.00 mm (KEDM 25%), 12.50 mm (KEDM 50%), and 12.60 mm (KEDM 75%). The antibacterial ZOI values of matoa leaf ethanol extract nanoparticles against S. mutans were 8.00 mm (KNDM 2.5%), 9.06 mm (KNDM 5%), and 10.10 mm (KNDM 7.5%). The conclusion is that ethanol extract of matoa leaves can be used as extract nanoparticles, where the extract nanoparticle concentration of 7.5% already has the ability of antibacterial activity that is close to the concentration of 25% ethanol extract, so that it can be said that the extract nanoparticle preparation can reduce the dose of a drug even though it is in the resistant category compared to Amoxicillin 25 g with the susceptible category.
UJI AKTIVITAS ANTIBAKTERI NANOPARTIKEL EKSTRAK ETANOL DAUN MATOA (Pometia pinnata J.R. Forst & G. Forst) TERHADAP BAKTERI Escherichia coli Huzeila Nisa Siregar; Yayuk Putri Rahayu; Haris Munandar Nasution; M Pandapotan Nasution
Jurnal Riset Kefarmasian Indonesia Vol. 5 No. 1 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i1.329

Abstract

Escherichia coli was one of the bacteria that causes diarrhea. Matoa leaves (Pometia pinnata J.R. Forst & G. Forst) ) is a plant from the Sapindaceae family and is known to have antibacterial compounds. This study aims to make ethanol extract of matoa leaves into extract nanoparticles and to determine the antibacterial activity of ethanol extract nanoparticles better than ethanol extract of matoa leaves against E. coli bacteria. This research was conducted experimentally with free variables, namely the concentration of matoa leaf ethanol extract (KEDM 25%; KEDM 50%; and KEDM 75%), and the nanoparticle concentration of matoa leaf ethanol extract (KNDM 2.5%; KNDM 5%; and KNDM 7.5%). The bound variable was the antibacterial activity of ethanol extract and nanoparticles of ethanol extract of matoa leaves against E. coli bacteria. Nanoparticle manufacturing uses the ionic glassing method with chitosan 0.1% and Na-TPP 0.1% (1:1). The nanoparticle size characterization of the extract used a Particle Size Analyzer (PSA). Antibacterial activity test using the diffusion method of Kirby Bauer's agar. The result of the characterization of the extract nanoparticles obtained a size of 324.97 nm. The value of the antibacterial Zone Of Inhibition (ZOI) of matoa leaf ethanol extract was 13.9 mm (KEDM 25%); 14.6 mm (KEDM 50%); and 18 mm (KEDM 75%). The antibacterial ZOI value of the ethanol extract nanoparticles was 6.6 mm (KNDM 2.5%); 7.2 mm (KNDM 5%); and 7.7 mm (KNDM 7.5%). The conclusion of this research was that matoa leaf ethanol extract can be used as an extract nanoparticle, where with a concentration of 2.5% extract nanoparticles already has antibacterial activity capability which is equivalent to half the dose of 25% ethanol extract concentration of matoa leaves, so it can be said that the extract nanoparticle preparation can reduce the dose of a drug by up to half the dose, even though it is in the resistant category compared to Tetracycline 30 μg.
Konsentrasi Hambat Minimum Dan Konsentrasi Bunuh Minimum Ekstrak Etanol Dan Nano Ekstrak Kulit Durian (Durio zibethinus murr) Terhadap Bakteri Staphylococcus epidermidis Tahnia Maulidya; Yayuk Putri Rahayu; Minda Sari Lubis; Haris Munandar Nasution
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 3 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i3.1925

Abstract

Introduction: Durian peel is a source of phytochemicals with antibacterial potential, and particle-size reduction may modify dispersion and measured in vitro activity. This study evaluated the operational minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of ethanol extract and a size-reduced ("nano extract") preparation of durian peel against Staphylococcus epidermidis. Methods: The ethanol extract was prepared by maceration with 96% ethanol; 30 g of the same extract was homogenized at 1,700 rpm for 1 h and ultrasonicated for 1 h. Particle size, phytochemical screening, broth absorbance at 600 nm, qualitative subculture, and disk diffusion were evaluated in triplicate (n=3). Inhibition-zone data were analyzed using one-way ANOVA. Results: The mean particle size was 645.72 nm. Operational MIC values were 6.25% for the ethanol extract and 0.625% for the nano extract, while no growth after subculture was observed at 50% and 5%, respectively. Mean inhibition zones ranged from 6.6-14.5 mm and 8.3-18.3 mm, with significant concentration-related differences within each series (p<0.001). Discussion and conclusion: The size-reduced preparation reached inhibitory endpoints at lower nominal concentrations within its test series. However, final concentrations were not analytically verified, and optical interference and qualitative bactericidal endpoints limit direct inference of intrinsic potency. These findings support in vitro antibacterial activity but do not establish a quantified increase in potency or a reduction in therapeutic dose
Co-Authors Adelia Ramadani Adelia Ramadani Adli Nuzula Rahmah Ahmad Gozali Siregar Alfi Wahyudi Nasution Amaliana, Amaliana Anny Sartika Daulay Ayu , Tri Indah Pagar Barutu, Liza Anisa Shevia Burju Artha Marshalina Silitonga Cici Niken Ariyanti Cindy Widya Rosa Br Simarmata Cynthia Syahni D Elysa Putri Mambang D. Elysa Putri Mambang D. Elysa Putri Mambang D. Elysa Putri Mambang D. Elysa Putri Mambang Delvi Amira Hutagaol Dena, Mutia Dikki Miswanda Elma Natasya Fatikasari, Cilki Fithri Pulungan, Ainil Fitri Mulyani, Fitri Gabena Indrayani Dalimunthe Ghalih Anwar Habibie, Dian Harahap, Azmi Kurniawan Harahap, Siti Salimah Harianto II Haris Munandar Nasution Haris Munandar Nasution Healthy Aldriany Prasetyo Hendri Gunawan Hutagaol, Delvi Amira Huzeila Nisa Siregar Ika Fitriani Ika Yeni Siahaan Khofifah , Nur Lastri Afni Leni Safriani Linda, Rosa Lisda Mayanti Lubis, Minda Sari Lubis, Nadya Frestika Lulu Ilma Khoirun Nissa M Pandapotan Nasution M Pandapotan Nasution M. Pandapotan Nasution M. Pandapotan Nasution M. Pandapotan Nasution Merani Phaustina Lumban Gaol Muhammad Amin Nasution Muhammad Arif Muhammad Hizbullah Muhammad Pandapotan Nasution Muhammad Wahyu Ikhsan Muhammad Wahyu Ikhsan Munaziatul Jannah Nadia Salsabilla Najwa Lailatulqodri Nanda Nadia Nasution , Muhammad Amin Nasution, M. Pandapotan Nelsa Fahira Nofa Lismandaria Nomi Noviani Novi Yuliandari Novika Utami Novriani Putri Santia Nurul Hasanah Oca Putri Nazuhra Oktavia, Sri Rahayu Rafita Yuniari Rafita Yuniart Rahmadani Rahmadani Rahman Halim Rati Satri Situmorang Ridwanto Ridwanto Rosalinda Mahdalena Sinaga Rosalinda Mahdalena Sinaga Rossa, Aliffa Safira , Liyuza Selfiani Selfiani Sepriani, Ananda Shilvia, Fatin Sinaga, Rosalinda Mahdalena Siti Aisyah Jamil Sony , Suyefri Sopha, Diana Sri Wahyuni Sri Wahyuni Supiyani, Supiyani Syarifah Elena Gultom Tahnia Maulidya Tawir Rina Rezeki Tusaddiah, Ria Winata, Ageng Tegar Yani, Farida Yayuk Yuliana Yayuk Yuniarti, Rafita Zulmai Rani