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Diah Mira Indramaya
Department Of Dermatology And Venereology Faculty Of Medicine Universitas Airlangga / Dr. Soetomo General Academic Hospital, Surabaya
Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Public Health Other

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Journal : Nusantara Medical Science Journal

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Profile And Treatment of Stevens-Johnson Syndrome Patients in DR. Soetomo General Hospital Anggun Tera Rahmasari; Diah Mira Indramaya; Pudji Lestari
Nusantara Medical Science Journal Volume 4 No. 2 Juli - Desember 2019
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v4i2.5696

Abstract

Background: Stevens-Johnson Syndrome (SJS) is a rare but potentially life- threatening form of Severe Cutaneous Adverse Reaction (SCAR). SJS is mostly caused by drugs and is associated with high morbidity and mortality. Moreover, no standard treatment has been established for SJS. The aim of this study is to present epidemiological features, etiologies, clinical outcomes, medical histories, and treatments of SJS patients at the Inpatient Units Kemuning I and II Dr. Soetomo General Hospital between 2011 until 2015.Methods: This retrospective study used secondary data collected from medical records. All patients in the Inpatient Units Kemuning I and II of Dr. Soetomo General Hospital from the year 2011 until 2015 who was diagnosed SJS were included in this study.Result: There were 29 medical records consisting of 23 females and 6 males with the diagnosis of SJS found in 2011-2015. Most patients were aged 25-44 years old, with no family history of SJS. A majority first presented with a clinical history of fever. The main cause of SJS in this cohort was amoxicillin. Mucosal areas that were involved the most was the eye and mouth. Systemic treatments for patients were corticosteroid. The average duration of treatment was 15,88 days. None of the patients died.Conclusion: SJS was more common in females compared to males. The main systemic therapy in Inpatient Units Kemuning I dan II of Dr. Soetomo General Hospital was intravenous cortiosteroid and no patients died.
Co-Authors AA Sudharmawan, AA Abdul Karim Ade Fernandes Afif Hidayati Afif Nurul Hidayati Afif Nurul Hidayati, Afif Nurul Agus Santoso Budi Amanda Gracia Manuputty Anggaraeni, Sylvia Anggun Tera Rahmasari Ardhiah Iswanda Putri Arifa Mustika Arifin Saiboo, Alvian Arisia Fadila Aruja Dhar Astindari Astindari Astindari, Astindari Azzahra, Alya Mutiara Bagus Haryo Kusumaputra, Bagus Haryo Bintanjoyo, Lunardi Brama Rachmantyo Budi Utomo Budi Utomo BUDI UTOMO Budiono Budiono Cita Rosita Sigit Prakoeswa Damayanti Damayanti Damayanti Damayanti Damayanti David Sontani Perdanakusuma Devi, Aprilin Krista Dewi Nurasrifah Diana Kartika Sari Dwi Murtiastutik Eliza, Frizka Esravila Ariya Wibisono Esti Hendradi Eva Lydiawati Evy Ervianti Fadila, Arisia Fania Ayu Wardani Farah Meriana Fajrin Hamiseno, Gifta Marshanda Qanitah Hari Sukanto, Hari Harningtyas, Citra Dwi Irmadita Citrashanty, Irmadita Irwadi, Irfiansyah Iskandar Zulkarnain Iswinarno Doso Saputro Izzatul Fithriyah Kristina Sihaloho Kristina Sihaloho Kristina Sihaloho, Kristina Lia Kinasih Ayuningati Lia Kinasih Ayuningati, Lia Kinasih Linda Astari, Linda M. Yulianto Listiawan Mah Zhook Yueng Marsudi Hutomo Marsudi Hutomo, Marsudi Maya Wardiana Maylita Sari Maylita Sari, Maylita Medhi Denisa Alinda, Medhi Denisa Meidyta Sinantryana Widyaswari, Meidyta Sinantryana Menul Ayu Umborowati Menul Ayu Umborowati Menul Ayu Umborowati Menul Ayu Umborowati, Menul Ayu Milan Muhammed Muslim, Ronaldo Mutiara Arikah Balqis Novia Indriyani Adisty Novia Indriyani Adisty, Novia Indriyani Nurfaiza, Diandra Yasmin Pepy Dwi Endraswari, Pepy Dwi Perdanakusuma, David Sontani Priangga Adi Wiratama Prida Ayudianti Pudji Lestari Rahmadewi Rahmadewi Rahmadewi Rebekah Setiabudi, Rebekah Renata Prameswari Ridha Ramadina Widiatma Riezky Januar Pramitha Riyana Noor Oktaviyanti Rochmanti, Maftuchah Rochmanti Rubianti, Marissa Astari Saleh Ashafi Salsabilla, Dhea Hasna Sawitri Sawitri Sawitri Sawitri Sawitri Sawitri Septiana Widyantari Subur Prajitno Sunarso Suyoso Sunarso Suyoso, Sunarso Tasya Wikassa Tengku Riza Zarzani N Triana Novitasari Trisniartami Setyaningrum Umi Miranti Wardiana, Maya Widyantari, Septiana Yuindartanto, Andre Yuli Wahyu Rahmawati Zahrah Hikmah, Zahrah Zahruddin Ahmad Zahruddin Ahmad Zarasade, Lobredia