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All Journal VALENSI Jurnal Al Bayan: Jurnal Jurusan Pendidikan Bahasa Arab Lisanuna: Jurnal Ilmu Bahasa Arab dan Pembelajarannya Indonesian Journal of Biotechnology Nady al-Adab EJI (English Journal of Indragiri) : Studies in Education, Literature, and Linguistics Bhamada: Jurnal Ilmu dan Teknologi Kesehatan (E-Journal) SCAFFOLDING: Jurnal Pendidikan Islam dan Multikulturalisme Jurnal ABDINUS : Jurnal Pengabdian Nusantara An Naba Jurnal Pemikiran dan Penelitian Pendidikan Islam MURHUM : JURNAL PENDIDIKAN ANAK USIA DINI Jurnal Abdimas Kartika Wijayakusuma Jurnal Penelitian Journal of Innovation and Research in Primary Education Jurnal Keperawatan Attaqwa:Jurnal Ilmu Pendidikan Islam Journal Research Midwifery Politeknik Tegal al Kimiya : Jurnal Ilmu Kimia dan Terapan Al-Tadris: Jurnal Pendidikan Bahasa Arab JI-KES (Jurnal Ilmu Kesehatan)
Umi Baroroh, Umi
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Religion Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Other

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PENGALAMAN IBU MENIKAH DINI YANG GAGAL MEMBERIKAN ASI EKSKLUSIF Hidayah, Seventina Nurul; Chikmah, Adevia Maulidya; Baroroh, Umi
JI-KES (Jurnal Ilmu Kesehatan) Vol. 4 No. 1 (2020): JI-KES (Jurnal Ilmu Kesehatan)
Publisher : LPPM Universitas Hafshawaty Zainul Hasan Probolinggo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33006/ji-kes.v4i1.164

Abstract

Selama pemberian ASI banyak alasan yang disampaikan ibu untuk tidak menyusui bayinya.   Pernikahan dini yang disertai dengan ketidaksiapan memberikan pola asuh yang baik akan berdampak pada status gizi anak terutama pemberian ASI Eksklusif. Air Susu Ibu (ASI) merupakan makanan terbaik bagi bayi setelah lahir yang mengandung nutrisi paling lengkap untuk pertumbuhan dan perkembangan bayi. ASI juga memiliki manfaat dalam mencegah terjadinya infeksi pada bayi. Namun, pemberian ASI Eksklusif masih terbilang rendah. Rendahnya cakupan menyusui dipengaruhi oleh banyak faktor, baik internal maupun eksternal. Penelitian ini bertujuan untuk mengeksplorasi pengalaman ibu menikah dini yang tidak berhasil memberikan ASI Eksklusif di wilayah Puskesmas Tegal Barat.Penelitian kualitatif menggunakan metode wawancara semistruktur dengan pendekatan fenomenologi. Wawancara dilakukan kepada 3 orang partisipan yang memiliki anak usia 6-12 bulan di Wilayah Puskesmas Tegal Barat. Sampel diambil menggunakan purposive sampling (variasi maksimal). Pernyataan responden dicatat dengan menggunakan perekam suara, dan kemudian ditranskipkan, dikodekan, ditafsirkan, dan dikategorikan, sehingga dapat membentuk tema.Hasil penelitian didapatkan lima tema, yaitu pengetahuan mengenai ASI Eksklusif, faktor yang menghambat keberhasilan ASI Eksklusif, peran tenaga kesehatan, cara yang dilakukan ibu untuk menambah produksi ASI dan makanan yang diberikan ibu untuk MPASI dini. Kesimpulan : Ketidakberhasilan pemberian ASI Eksklusif dipengaruhi oleh banyak faktor yaitu pengetahuan ibu yang kurang, terjadinya rawat pisah, rendahnya frekuensi menyusui langsung, terjadinya sindrom ASI kurang, pemberian susu formula sebelum ASI, pemberian MPASI dini dan penggunaan KB.  Kata kunci : Ketidakberhasilan, ASI Eksklusif
The Impact of Asian Parliamentary Debate Techniques on the Arabic Speaking Skills of University Students: Penerapan Debat Parlementer Asia untuk Meningkatkan Kemampuan Berbicara Bahasa Arab di Perguruan Tinggi Al Kautsar, Naafi; Mustofa, M. Tulus; Baroroh, Umi
Nady Al-Adab : Jurnal Bahasa Arab Vol. 22 No. 2 (2025): Nady al-Adab
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jna.v22i2.45351

Abstract

This study investigates the impact of Asian Parliamentary Debate (APD) techniques on the Arabic speaking skills of university students, specifically those in the Arabic Language Education program at UIN Sunan Kalijaga. Speaking skills, particularly in Arabic, are essential for students’ academic and professional success, yet many face challenges in mastering fluency, confidence, and argumentation. This research aims to evaluate the potential of APD in improving speaking skills, specifically fluency, self-confidence, and argumentative construction in Arabic. This qualitative study utilizes a descriptive methodology, incorporating observation, semi-structured interviews, and document analysis to collect data from second-semester students engaged in APD sessions. The study indicates notable advancements in students' speaking abilities, especially in areas of self-confidence, fluency, and argumentation. After three cycles of debate, students exhibited an increase in self-confidence from 60% to 90%, an improvement in fluency from 55% to 89%, and an enhancement in their ability to construct arguments from 50% to 90%. Furthermore, participation in debates also increased, from 60% to 95%. Interviews with students highlighted the positive effects of APD on overcoming public speaking fears and enhancing critical thinking. The findings suggest that APD techniques foster a dynamic and interactive learning environment that not only improves speaking skills but also boosts student engagement and critical thinking. These results contribute to the growing body of research on the effectiveness of debate techniques in language education, particularly in Arabic. The study recommends incorporating APD into Arabic language curricula to further enhance students' speaking abilities. Future research should explore the long-term effects of APD and its application in other language learning contexts
Exploring Brazilin as a Potential Breast Cancer Therapy via Molecular Dynamics Simulation Targeting ERα, 17β-HSD1, and NUDT5 Receptors Baroroh, Umi; Dasilva, Jasmine Aulia; Sundalian, Melvia; Astriany, Dewi; Ansori, Arif Nur Muhammad; Yee, Jonie C.
Jurnal Kimia Valensi Jurnal Kimia VALENSI, Volume 11, No. 2, November 2025
Publisher : Department of Chemistry, Faculty of Science and Technology Syarif Hidayatullah Jakarta State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/jkv.v11i2.46465

Abstract

Breast cancer remains one of the leading causes of cancer-related mortality worldwide, suggesting the need for novel therapeutic agents with greater efficacy and fewer side effects. Brazilin, a natural flavonoid compound isolated from Caesalpinia sappan L., has shown promising anticancer activity, particularly against breast cancer cells. This study explores the therapeutic potential of brazilin by evaluating its interactions with three key molecular targets: estrogen receptor alpha (ERα), 17β-hydroxysteroid dehydrogenase 1 (17β-HSD1), and Nudix hydrolase 5 (NUDT5). Using molecular dynamics (MD) simulations, the study assesses the stability and binding interactions of complex systems. The results indicate that brazilin forms a stable complex with ERα, demonstrated by a low RMSD (2.6 Å) and strong hydrogen bonding with Glu353, occupancies of 97.8%, and minimal flexibility at the binding site (average RMSF < 2.5 Å). The binding free energy (ΔG Total) for the ERα–brazilin complex was -54.28 kcal/mol, indicating a stronger affinity than the reference ligand 4-hydroxytamoxifen. Brazilin also showed favorable binding with 17β-HSD1 and NUDT5, with binding energies of -39.71 kcal/mol and -23.23 kcal/mol, respectively. These findings suggest that brazilin may modulate critical targets involved in breast cancer progression, particularly in hormone receptor-positive subtypes. Further experimental validation is necessary to confirm its efficacy and optimize its therapeutic potential.
Peningkatan Pemberian ASI Ekslusif Melalui Pendidikan Kesehatan Tentang Kecukupan ASI Nisa, Juhrotun; Baroroh, Umi; Fitrianingsih, Desy
Jurnal ABDINUS : Jurnal Pengabdian Nusantara Vol 6 No 3 (2022): Volume 6 Nomor 3 Tahun 2022
Publisher : Universitas Nusantara PGRI Kediri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29407/ja.v6i3.16796

Abstract

Adequate breastfeeding is very beneficial for the immune system, as well as the growth and development of babies, but the achievement of exclusive breastfeeding is still low. Knowledge is considered the most dominant factor in the success of breastfeeding, so this community service is carried out with the aim of increasing the knowledge of pregnant women about the adequacy of breastfeeding. The method used is the expert method in the form of health counseling related to exclusive breastfeeding, how to assess the adequacy of breast milk, production and demand for breast milk including expressed breast milk and how to increase milk production. The target of this activity is pregnant women at the Debong Lor Public Health Center. The result of this service activity is that there is an increase in the knowledge of pregnant women about the adequacy of breastfeeding. The data was obtained from the comparison of the results of the pretest and posttest. Health workers are expected to provide information about breastfeeding since pregnancy and the family can support exclusive breastfeeding.
Generation of a bivalent dengue virus-like particle targeting DENV-1 and DENV-2 in Pichia pastoris Kusumawardani, Shinta; Yusuf, Muhammad; Yosua, Yosua; Syafrudin, Elza Nurrachmanita; Baroroh, Umi; Nurainy, Neni; Subroto, Toto
Indonesian Journal of Biotechnology Vol 31, No 2 (2026)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijbiotech.114770

Abstract

Dengue remains a major global health concern, with current licensed vaccines offering variable protection across the four virus serotypes and posing safety considerations related to antibody-dependent enhancement (ADE). To contribute toward improved vaccine design, we developed a bivalent virus-like particle (VLP) targeting DENV-1 and DENV-2, the two most prevalent serotypes in Indonesia. Consensus envelope (CE) protein sequences from Indonesian DENV-1 and DENV-2 strains were codon-optimized and co-expressed in Pichia pastoris GS115 using the AOX1 promoter. The expressed proteins were solubilized from membrane fractions under denaturing conditions, purified via Ni2+-affinity chromatography, and subjected to urea gradient dialysis for VLP assembly. Transmission electron microscopy confirmed the formation of spherical VLPs. Western blot analysis confirmed expression and purification via anti-His detection, and supported antigenic integrity of the envelope proteins as recognized by anti-dengue E antibodies. The study demonstrates the feasibility of using P. pastoris for chimeric dengue VLP production based on regionally relevant strains. The findings support the development of serotype-focused VLP platforms as modular components in the development of future tetravalent dengue vaccines.
Co-Authors A. Hasan, Adtman Adevia Maulidya Chikmah, Adevia Maulidya Adi Sofyan Ansori, Muhammad Al Kautsar, naafi Andi Prastowo Ardiansyah, Seno Aulia As-Sa’idah, Rahmah Bunyamin Dasilva, Jasmine Aulia Desy Fitrianingsih, Desy Dewi Astriany Edi Ardian, Edi Faiza Rahma, Vika Fauzi, Novi Irwan Hardiyati, Mikyal Hardiyati, Mikyal I Made Sudana Ilma Ratih Zukrufiana Juhrotun Nisa, Juhrotun Kelana, Himalaya Wana Khotibul Umam Krisna Bayu, Krisna Kusumawardani, Shinta Mahariah Mardiah, Irma Maulida, Iroma Melvia Sundalian Meyliya Qudriani Meyliya Qudriani Meyliya Qudriani, Meyliya Muhammad Fairuz Rosyid Muhammad Yusuf Mukadam, Abdur Rasheed-Mahmoud Mustofa, M. Tulus Nela, Nela Nora Rahmanindar, Nora Nurainy, Neni Oktaviani, Sulistya Sabarudin Sabarudin Setiani, Nur Asni Seventina Nurul Hidayah, Seventina Nurul Syafrudin, Elza Nurrachmanita Syakir, Mukhlis Toto Subroto Ulfatul Latifah, Ulfatul Umi Baroroh Viranti, Milfa Wahidah, Zulfa Amalia Yee, Jonie C. Yosua Yosua