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All Journal Journal of Food and Pharmaceutical Science JURNAL GIZI INDONESIA Media Kesehatan Masyarakat Indonesia Media Gizi Mikro Indonesia Journal of the Medical Sciences (Berkala Ilmu Kedokteran) agriTECH Jurnal Pengabdian Kepada Masyarakat (Indonesian Journal of Community Engagement) Paediatrica Indonesiana GIZI INDONESIA Jurnal Gizi dan Dietetik Indonesia (Indonesian Journal of Nutrition and Dietetics) JNKI (Jurnal Ners dan Kebidanan Indonesia) (Indonesian Journal of Nursing and Midwifery) Jurnal Gizi Klinik Indonesia Amerta Nutrition Journal of Community Empowerment for Health Jurnal Dunia Gizi Narra J JURNAL KESEHATAN SAMODRA ILMU Berita Kedokteran Masyarakat Proceeding ISETH (International Summit on Science, Technology, and Humanity) Journal of Food and Pharmaceutical Sciences
Emy Huriyati
Department Of Health Nutrition, Faculty Of Medicine, Public Health, And Nursing, Universitas Gadjah Mada, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Education Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Journal : Paediatrica Indonesiana

 1 
Magnesium intake and insulin resistance in obese adolescent girls Harry Freitag Luglio Muhammad; Emy Huriyati; Rina Susilowati; Madarina Julia
Paediatrica Indonesiana Vol 49 No 4 (2009): July 2009
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (110.325 KB) | DOI: 10.14238/pi49.4.2009.200-4

Abstract

Background The worldwide increase in the prevalence ofcardiovascular diseases in adulthood is related to obesity inchildren and adolescents. Insulin resistance and hyperinsulinemia observed in obese individuals are the precursors of cardiovascular diseases and type 2 diabetes mellitus. Magnesium, through its action on insulin receptors, is proposed to be an important factor in preventing insulin resistance.Objective The aim of this study was to assess the associationbetween magnesium intake and insulin resistance in obeseadolescent girls.Methods This was a cross-sectional study on obese adolescentgirls in Yogyakarta, Indonesia. Insulin resistance was defined as a HOMA-IR index of3.16 or more. HOMA-IR was calculated usingfasting insulin and plasma glucose levels. Magnesium intake andenergy adjusted magnesium intake were measured using a 24-hour food recall method on 6 non-consecutive days.Results Of 7 8 obese adolescent girls included in our study, 56% of them were found to be insulin resistant. Magnesium intake was only 61 o/o of the recommended daily requirement for adolescent girls. There were no significant associations between magnesium intake and either HOMA-IR or hyperinsulinemia.Conclusion Our study does not find an association betweeninsulin resistance and magnesium intake in obese adolescent girls.
The role of genetic variation in TCF7L2 and KCNJ11, dietary intake, and physical activity on fasting plasma glucagon-like peptide-1 in male adolescents Harry Freitag Luglio; Emy Huriyati
Paediatrica Indonesiana Vol 57 No 5 (2017): September 2017
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (386.787 KB) | DOI: 10.14238/pi57.5.2017.239-45

Abstract

Background Transcription factor 7-like 2 (TCF7L2) and potassium voltage-gated channel subfamily j member 11 (KCNJ11) gene polymorphisms have been associated with type 2 diabetes mellitus (T2DM) via regulation of insulin production. Ingested nutrients induce glucagon-like peptide-1 (GLP-1), which in turn induces insulin secretion.Objective To evaluate the relationship between TCF7L2 and KCNJ11 gene polymorphism, dietary intake, and physical activity on fasting plasma GLP-1 in normal male adolescents.Methods This observational study with a cross-sectional design included 54 male adolescents selected from high schools in Yogyakarta, Indonesia. Interviews were done to collect data on energy intake and physical activity. The GLP-1 and insulin levels were measured from fasting blood plasma. The TCF7L2 and KCNJ11 gene polymorphisms were analyzed by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP).Results Fasting GLP-1 was positively correlated with energy intake (r=0.276; P=0.047), but not with physical activity (r=0.011; P=0.936). The GLP-1 concentration was not associated with TCF7L2 and KCNJ11 gene polymorphisms (all P>0.05). In subjects with an EE genotype (KCNJ11), GLP-1 was not correlated with insulin (r=-0.036; P=0.435). However, in subjects with an EK genotype (KCNJ11), GLP-1 was positively correlated with insulin (r=0.394; P=0.026).Conclusion GLP-1 concentration is positively correlated with body weight. Among male adolescents with a genetic variation in KCNJ11 (EK genotype), there is a significant correlation between GLP-1 and insulin signalling.
Co-Authors A’yun, Rizka Qurrota Abdul Wahab Abeng, Andi Tenri Abidillah Mursyid Adhila Fayasari Ahmad Hamim Sadewa Ailsa Nur Rahma Apta Widyadhana Aini, Reza Hanifatus Akhmad Sujai Almira Nadia Alpha Olivia Hidayati Andi Tenri Abeng Annisa Leny Saraswati Arta Farmawati Atika Sulistyan Ave Anugraheni Cati Martiyana Christin Debora Nabuasa Dangga, Victorianus Daniel Robert Daniel Robert, Daniel Darwin Nasution Detty Siti Nurdiati Dewi Marfuah Dian Caturini Sulistyonigrum Djauhar Ismail Djauhar Ismail Djauhar Ismail Djauhar Ismail Dwi Sarbini Dyah Ayu Kusuma Wardani Elisabeth Pampang Eni Harmayani Eni Harmayani Erinda Nurrahma Fajar Sri Tanjung Fatwa Sari Tetra Dewi Fitri Ardiani Fitri Ardiani Gebang, Antonius Adolf Hamam Hadi Hamam Hadi Hamam Hadi Hamam Hadi Happy Nurlita Octavinanda Hardiana Probosiwi Hari Kusnanto Harry Freitag Luglio Muhammad Hidayah, Rizki Amalia Husnah Husnah Inas Nur Hafizhah Janatin Hastuti Juffrie, M Kamsiah . Kantari, Eka Suci Khristina Dias Utami Lastiana Safitri Lastiana Safitri, Lastiana Latifah Mahdiyati Lely Lusmilasari, Lely Lily Arsanti Lestari Lisdrianto Hanindriyo Lisma Evareny, Mohammad Hakimi, Retna Siwi Padmawati M Juffrie Madarina Julia Madarina Julia Madarina Julia Madarina Julia Mae Sri Hartati Wahyuningsih Maria Goretti Adiyanti Maria Goretti Adiyanti, Maria Goretti Martalena Br Purba Martalena Br Purba Martalena Br Purba Martalena Br Purba, Martalena Br Mirza Hapsari Sakti Titis Penggalih Mubasysyir Hasanbasri Mubasysyir Hasanbasri Muhammad Jourdan Prasetyatama Mursyid, Abidillah Mustikaningtyas Mustikaningtyas Mustikaningtyas, Mustikaningtyas Mutiara Tirta Prabandari Lintang Kusuma Nabuasa, Christin Debora Nailufar, Farida Nasution, Darwin Ni Komang Wiardani Ningrum, Ema W. Nisa, Ainun Nisa, Fatma Zuhrotun Nur Fitri Widya Astuti Nurahma, Bira Arumndari Okta Haksaica Sulistyo Pampang, Elisabeth Perdana Samekto Tyasnugroho Suyoto Podojoyo Podojoyo Podojoyo, Podojoyo RAHMANIAH RAHMANIAH Ramadhaniah Ramadhaniah Ramadhaniah, Ramadhaniah Ratih Feraritra Danu Atmaja Refdiana Dewi Ribia Tutstsintaiyn Rina Susilowati Rina Susilowati Rissa Saputri Rizka Qurrota A’yun Ronny Tri Wirasto Rupiasa, Welresna Juliatri Putri Sadewa, Hamim Saputri, Aulia Rahmadini Saputri, Rissa Siti Wahdah Sri Ahadi Nugraheni Sri Ahadi Nugraheni, Sri Ahadi Sri Rahayoe Sujai, Akhmad Sulistyan, Atika Sulistyo, Okta Haksaica Sunarti, Sunarti Supriyati Susetyowati Susilo, Leonardus Reynald Tiara Marthias Toto Sudargo Toto Sudargo Usi Lanita Utami, Nurul Putrie Wardani, Dyah Ayu Kusuma Winda Irwanti Winda Irwanti, Winda Wirasto, Ronny Tri Wiryatun Lestariana Wiryatun Lestariana Wiryatun Lestariana, Wiryatun Yayi Suryo Prabandari Yusmiati Yusmiati Yusmiati Yusmiati, Yusmiati Zahra Anggita Pratiwi