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Anthocyanin Compounds from Ethanol Extract of Red Fruit (Pandanus conideus L.): A Functional Group Analysis Indah Amelia Rizky; Angga Bayu Budiyanto; Lukman Hardia
Jurnal Penelitian Pendidikan IPA Vol 10 No 11 (2024): November
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i11.9321

Abstract

Red Fruit (Pandanus conoideus L.) is a typical Papuan plant that is rich in bioactive compounds such as anthocyanins, which have the potential to act as antioxidants. This research aims to analyze the chemical structure of anthocyanin compounds from red fruit ethanol extract using Fourier Transformed Infrared (FTIR) spectroscopy. FTIR is a spectroscopic tool widely used to characterize or detect functional groups and qualitatively identify compounds in samples. Anthocyanins act as antioxidants and have various biological activities such as preventing cancer, cardiovascular disease, and diabetes. Extraction was carried out using the maceration method using 70% ethanol solvent, and characterization was performed using FTIR in the wave range 4000-450 cm⁻¹. The results of the research that has been carried out show that the ethanol extract of red fruit contains secondary metabolites such as flavonoids, alkaloids, and saponins. The FTIR results of red fruit extract show the presence of functional groups characterized by the presence of the O-H, C-O-C, C-O, and C=C functional groups which are important indicators of the antioxidant properties of anthocyanins. This research confirms the potential of Red Fruit as a natural source of anthocyanins which are useful as antioxidants
Analysis of administrative-pharmaceutical completeness on patient prescriptions at Puskesmas X, Sorong City Carmel Josuhua Paulus; Lukman Hardia; Angga Bayu Budiyanto
Science Midwifery Vol 14 No 2 (2026): Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v14i2.2374

Abstract

Prescription completeness is an important indicator in pharmaceutical services because it is related to therapeutic accuracy and patient safety. Incomplete prescriptions may increase the risk of medication errors during drug preparation and administration. This study aimed to determine the level of administrative and pharmaceutical completeness of patient prescriptions at Puskesmas X, Sorong City. This research used a descriptive observational method with a retrospective approach involving 1,572 patient prescriptions selected using a total sampling technique. The assessment was conducted based on the standards of the Indonesian Ministry of Health Regulation Number 73 of 2016 and Number 58 of 2014. The results showed that all prescriptions (100%) were categorized as incomplete. In the administrative aspect, patient name and prescription date reached 100% completeness, while patient height, doctor’s practice license number, and doctor’s phone number showed 0% completeness. Doctor’s initials/signature were found in 60.8% of prescriptions. In the pharmaceutical aspect, drug name, stability, and compatibility reached 100% completeness, while dosage form and drug strength reached 70.6% and 69.3%, respectively. The study concluded that pharmaceutical completeness was better than administrative completeness; however, prescription writing at Puskesmas X, Sorong Citis still, did not meet pharmaceutical service standards.
Efektivitas Kulit Buah Naga Merah (Hylocereus Polyrhizus) sebagai Antikolesterol Lukman Hardia; Rizqi Fadil Nadila; Wahyuni Watora
Jurnal Sains & Kesehatan Vol 5 No 1 (2026): Jurnal Sains dan Kesehatan
Publisher : Politeknik Baubau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57151/jsika.v5i1.1698

Abstract

Hypercholesterolemia is a condition where blood cholesterol levels exceed normal limits, becoming a risk factor for coronary heart disease. The skin of the red dragon fruit (Hylocereus polyrhizus) contains flavonoids, betayanin, and dietary fiber that have the potential to lower cholesterol levels. This study aims to determine the effectiveness and optimal dose of red dragon fruit peel extract as a cholesterol lowering in white rats of the Wistar strain (Rattus novergicus) induced by high cholesterol feed. This study used the pretest and post-test with control group design method, with 25 mice divided into 5 groups: negative control, positive control (simvastatin 10mg) and treatment groups with extract doses of 15, 30, and 60 mg/kg BB. The results showed that red dragon fruit peel extract had the effectiveness of hypercholesterolemia with a dose of 60mg/kgBB providing the most optimal reducing effect. Conclusion: Ethanol extract of red dragon fruit peel can significantly lower cholesterol levels in rats with hypercholesterolemia.
Co-Authors A. M. Muslihin Achmad Noerkhaerin Putra Agus sangka pratama Angga Bayu Budianto Angga Bayu Budiyanto Anisa, Meilinda Aponno, Alyssa Mileta Arif Radhika Mentari Arni, Veni Zafi Assem, Vincentia Santy Astuti, Ratih Arum Aulia Mifthakul Jannah Budianto, Angga Bayu Carmel Josuhua Paulus Darmayanti Tumpu Diah Wulandari Dian Nur Khofifah Dika Rahayu Dion Fahcrul Rozi Eka Savira Ni'ma Arfiani Erawati, Rika Ernifan Ernifan Eva Maya Sari Fabanyo, Syahrul H. fania, vikafania Fransiska, Gilda Indah Amelia Rizky Indah Diah Ningrum Irwandi Irwandi Irwandi Irwandi Irwandi Irwandi Irwandi Jannah, Aulia Mifthakul Lanipi, Retna Parica Lanipi, Retna Paricca Levina Virginia M Natsir Djide M. Yogi Riyantama Isjoni Mansyur Arief Maulana, Fajar Meilinda Anisa Muh Ishar Difinubun Nanik Sulistyani Nazla Wati Sanaky Ningrum, Indah Diah Nuhidayah Sarifuddin Nuhidayah Sarifuddin Nur ‘Azah Nurwahyuni Paulus, Johan Kartino Pratama, Agus Sangka putri puspitawati, devyana Rahayu, Dika Rasi Fitri Yanti Tuasikal Retna Parica Lanipi Retna Parica Lanipi Retna Paricca Lanipi Rizqi Fadil Nadila Rossardy, Marzella Dea Sanaky, Nazla Wati Sarifuddin, Nuhidayah Selfiana Iek Serlin Marsela Sintya Sari Dwi Kusumaningrum Siska Siska Siti Fatma Z.F. Sun, Suny Syahrul H. Fabanyo Titiek Suhardi Haripurnomo Kushadiwijaya Hidayati Tuasikal, Rasi Fitri Yanti Tunnazilah, Nurhikmah Tutuhatunewa, Priscillia Ryani ulandari, clarista windi Umpain, Agnes Nesa Utami, Hikmahtul Putri Vincentia Santy Assem Wa Ode Nurwahida Wael, Muh. Dahlan Wahyuni Watora Wasaraka, Fadila Alfiah Watora, Wahyuni Wiwik Triyani Wiwik Wiwik, Wiwik Triyani Yanti, Inda Dwi Yapsenang, Amar Jansen Yuniatri, Nur Khusna Yusnita La Goa Zf, Siti Fatma