Article Per Year (5 Year)
p-Index From 2021 - 2026
9.413
P-Index
This Author published in this journals
All Journal Pharmaciana: Jurnal Kefarmasian Jurnal Penelitian Pendidikan IPA (JPPIPA) Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) Jurnal Kesehatan Manarang Jurnal Pendidikan Biolearning Journal Jurnal Abdimasa PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Ners Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Science Midwifery Jurnal Promotif Preventif Jurnal Kesehatan Tambusai JOURNAL LA MEDIHEALTICO International Journal of Health, Economics, and Social Sciences (IJHESS) Jurnal EduHealth Jurnal Sains dan Teknologi Sci-Tech Journal Jurnal Sains dan Kesehatan Jurnal Ilmiah Ilmu Terapan Universitas Jambi Journal of Pharmaceutical and Sciences. Jurnal Etnofarmasi Jurnal Mahasiswa Ilmu Kesehatan Journal of Public Health and Pharmacy Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Ilmu Kesehatan Jurnal Etnofarmasi
Lukman Hardia
Universitas Pendidikan Muhammadiyah Sorong
Aerospace Engineering Agriculture, Biological Sciences & Forestry Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

Published : 69 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 69 Documents
Search

 3   4   5   6   7 
Antibacterial Activity Testing of Methanol Extract of Yellow Rope Barb (Anamirta cocculus) Wa Ode Nurwahida; A.M. Muslihin; Lukman Hardia
Jurnal Penelitian Pendidikan IPA Vol 11 No 4 (2025): April
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i4.10760

Abstract

Indonesia has abundant natural wealth. One of the endemic plants of Papua which is often used in traditional medicine is yellow rope (A. cocculus). This study aims to determine the antibacterial activity of methanol extract of yellow rope bark (A. cocculus) against P. acnes, S. aureus, and E. coli bacteria using an experimental microbiological approach in the laboratory, and the experiment model may also serve as a contextual laboratory-based learning resource in microbiology education. The antibacterial activity test was carried out using the disc diffusion method which was made in 3 concentrations, namely 5%, 10% and 15%. The results of measuring the diameter of the inhibition zone showed that each concentration was able to inhibit the growth of P. acnes bacteria with an average diameter of 2,816 mm (Weak), 6,733 mm (Medium), 9,333 mm (Medium), and control (+) clindamycin 2 μg 14,483 mm (Strong). S. aureus bacteria with an average diameter of 3.133 mm (Weak), 6.35 mm (Medium), 8.235 mm (Medium) and control (+) clindamycin 2 μg 20.97 mm (Very strong). E. coli bacteria showed an average diameter of 3.875 mm (Weak), 6.175 mm (Medium), 8.566 mm (Medium) and control (+) ciprofloxacin 5 μg 20.783 mm (very strong). This research shows that the methanol extract of yellow stem bark (A. cocculus) has antibacterial activity.
Pengaruh Konsentrasi Ekstrak Etanol Metimun (Cucumis sativus L.) Terhadap Konsentrasi Antioksidan dalam Sediaan Masker Gel Peel Off Fransiska, Gilda; Watora, Wahyuni; Hardia, Lukman
Jurnal Sains & Kesehatan Vol 4 No 2 (2025): Jurnal Sains dan Kesehatan
Publisher : Politeknik Baubau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57151/jsika.v4i2.1590

Abstract

Salah satu tanaman yang berpotensi sebagai sumber antioksidan alami adalah mentimun (Cucumis sativus L.). Kandungan air yang tinggi serta keberadaan vitamin C dan flavonoid di dalam mentimun berperan dalam aktivitas antioksidan dengan mekanisme menghambat, menangkap, maupun memutus reaksi radikal bebas yang bersifat sangat reaktif dan dapat memicu terbentuknya radikal bebas baru. Berdasarkan hasil uji fitokimia, ekstrak mentimun diketahui mengandung beberapa senyawa metabolit sekunder, seperti alkaloid, flavonoid dan saponin. Pemanfaatan bahan tersebut sebagai sediaan kosmetik berbentuk masker gel peel off dinilai sangat tepat. Jenis masker ini memiliki keunggulan dari segi kepraktisan karena setelah mengering dapat dilepaskan langsung dari permukaan kulit tanpa harus dibilas terlebih dahulu. Penelitian ini bertujuan untuk menganalisis pengaruh perbedaan konsentrasi ekstrak etanol mentimun (Cucumis sativus L.) yang diformulasikan dalam masker gel peel off terhadap aktivitas antioksidan yang dihasilkan. Metode yang digunakan adalah metode DPPH (2,2-diphenyl-1-picrylhydrazil atau 1,1-diphenyl-2-picrylhydrazil). Sediaan masker gel peel off diformulasikan dengan variasi konsentrasi ekstrak, yaitu 0,5% pada formula I, 1% pada formula II, dan 1,5% pada formula III. Nilai IC₅₀ yang diperoleh dari pengujian masker gel peel off pada F1 dengan konsentrasi ekstrak 0,5% menunjukkan hasil bernilai negatif sehingga IC₅₀ tidak dapat ditentukan, sedangkan ekstrak 1% (F2) memiliki nilai IC₅₀ sebesar 230,7 ppm dan ekstrak 1,5% (F3) sebesar 79,29 ppm, yang menunjukan peningkatan aktivitas antioksidan seiring dengan meningkatnya konsentrasi ekstrak dalam sediaan masker.
Analgesic effectiveness test of kitolod leaf ethanol extract (isotoma longiflora l.) against male white mice (mus musculus) Yanti, Inda Dwi; Budiyanto, Angga Bayu; Hardia, Lukman
Science Midwifery Vol 13 No 6 (2026): February: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i6.2227

Abstract

This study aims to evaluate the analgesic effectiveness of ethanol extract of Kitolod leaves (Isotoma longiflora L.) in male white mice (Mus musculus). Kitolod leaves are traditionally used as herbal remedies for pain, yet scientific evidence regarding their analgesic potential remains limited. This true experimental research employed a pre- and post-test with control group design, involving five groups: negative control (Na-CMC 1%), positive control (diclofenac sodium 50 mg), and three treatment groups administered Kitolod leaf extract at doses of 56 mg/kgBW, 112 mg/kgBW, and 224 mg/kgBW. Extract preparation was carried out using maceration with 96% ethanol, followed by phytochemical screening which confirmed the presence of flavonoids, alkaloids, tannins, and steroids. Analgesic activity was assessed using the tail flick method by measuring latency response to thermal stimuli at intervals of 30, 60, 90, 120, 150, and 180 minutes post-treatment. The results showed that Kitolod leaf extract increased pain response latency, with the 112 mg/kgBW and 224 mg/kgBW doses demonstrating the strongest analgesic effects comparable to diclofenac sodium. Statistical analysis using independent sample t-test and one-way ANOVA indicated significant differences (p < 0.05) between treatment and control groups. These findings suggest that Kitolod leaf ethanol extract possesses promising analgesic properties and may serve as a potential natural alternative for pain management.
ANALISIS BIBLIOMETRIK PENELITIAN ETNOMEDISIN A.M. Muslihin; Lukman Hardia
JURNAL ETNOFARMASI Vol. 2 No. 01 (2024): JURNAL ETNOFARMASI
Publisher : Universitas Pendidikan Muhammadiyah Sorong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36232/jurnalfarmasiunimuda.v2i01.1713

Abstract

Ethnomedicine is the study of certain communities in using medicines. Information on the use of medicinal plants can be provided using an ethnomedicine approach. Ethnomedicine as a method that can be used to explore the use of medicinal plants can be the first step to developing new medicines. Knowledge about how to process traditional ingredients used in certain community groups can be used as a reference in developing medicinal raw materials. Research on the use of medicinal plants in various communities (cross-cultural studies) can be used to find drugs and bioactive compounds. Ethnomedicine is an important stage in screening, selecting and developing new medicines derived from plants. Ethnic communities in an area have unique culture and local wisdom due to regional differences. This has an impact on knowledge about traditional medicine and medicine. Various tribes or ethnic groups in Indonesia have their own experiences in dealing with health problems. Ethnomedicine is part of a community's traditional medicine, often empirically proven, scientifically validated, for the discovery or development of new medicinal compounds.
UJI FISIK SEDIAAN SABUN CAIR EKSTRAK ETANOL DAUN MANGROVE (Rhizophora mucronata) Rasi Fitri Yanti Tuasikal; Irwandi Irwandi; Lukman Hardia
JURNAL ETNOFARMASI Vol. 2 No. 01 (2024): JURNAL ETNOFARMASI
Publisher : Universitas Pendidikan Muhammadiyah Sorong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36232/jurnalfarmasiunimuda.v2i01.1715

Abstract

Caffeic acid, vanillic acid, p-hydroxy benzoic acid, tannins, kau-16-ene, benzophene, phenolic compounds of the flavonoid group, phenolic acids, and dihydroflavonol tannins are all present in mangrove leaves. Alkaloids, coumarins, flavonoids, phenols and polyphenols, quinones, resins, saponins, phytosterols, tannins, xantoprotins, pigments (chlorophyll, carotenoids), and sugars are just some of the substances that can be found in plants. This plant has potential as an antibacterial, antimalarial, antiviral, and antioxidant. The purpose of this study was to obtain the formulation of Mangrove leaf ethanol extract liquid soap preparation and also know the physical properties of black mangroves leaf extract liquid soap preparation. In this study, physical tests of preparations such as organoleptic tests, pH tests, viscosity tests, and foam height tests were carried out. The results in organoleptic test research meet SNI standards, the Ph test has a high pH value of F1 12.71, the dosage properties become more alkaline, the viscosity test results meet SNI standards, while for the high test F3 foam has a high value of 84.91 so that it exceeds the SNI standard.
UJI EFEKTIVITAS ANALGESIK EKSTRAK ETANOL BUAH MERAH (Pandanus conoideus) TERHADAP MENCIT (Mus musculus) Nazla Wati Sanaky; Lukman Hardia; Irwandi Irwandi
JURNAL ETNOFARMASI Vol. 2 No. 01 (2024): JURNAL ETNOFARMASI
Publisher : Universitas Pendidikan Muhammadiyah Sorong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36232/jurnalfarmasiunimuda.v2i01.1717

Abstract

Many traditional plants have analgesic activity and can be used as alternative therapy. One plant that can be used for analgesic activity is Buah Merah (P. conoideus). Red fruit (Pandanus conoideus) is a medicinal plant that is well known and has proven its efficacy. The results of the phytochemical screening of red fruit, contained several active compounds, namely: tannins, flavonoids, saponins and alkaloids. The aim of this research is to determine the effectiveness of red fruit (P. conoideus) ethanol extract in providing an analgesic effect on mice (Mus musculus). This research used an analgesic meter and male mice as experimental animals. Each group was given treatment, the positive control group was given paracetamol, dose group 1 was given suspension with a concentration of 10%, dose 2 was given suspension with a concentration of 20% and dose group 3 was given 30% suspension then left for 30 minutes then placed on an analgesic meter until the mice writhe, then observe the response that appears. The response of mice from each group was observed for 30, 60, 90 and 120 minutes. The results of the one-way anova test showed that there was an influence and significant differences between the treatment groups. The results show that the ethanol extract of red fruit (P. conoideus) has an analgesic effect on mice (Mus musculus) and a concentration of 20% has the most effective analgesic activity.
FORMULASI DAN UJI EFEKTIVITAS SALEP EKSTRAK ETANOL DAUN MANGROVE (Rhizophora mucronata) TERHADAP PENYEMBUHAN LUKA SAYAT PADA MENCIT (Mus muscullus) Wiwik Triyani Wiwik; Irwandi Irwandi; Lukman Hardia
JURNAL ETNOFARMASI Vol. 2 No. 01 (2024): JURNAL ETNOFARMASI
Publisher : Universitas Pendidikan Muhammadiyah Sorong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36232/jurnalfarmasiunimuda.v2i01.1718

Abstract

Mangrove (Rhizophora mucronata) contains flavonoids, saponins and tannins. Compounds contained in mangrove leaves have antiinflammatory, anti viral and antimicrobial activites. Based on the compound, mangrove (Rhizophora mucronata) can be used an ointment for cuts. This study aims to test the preparation ofmangrove leaf ethanol extract ointment on the healing of cuts in mice. The process of extracting mangrove leaves (Rhizophora mucronata) uses the maceration method. In testing the ointment preparations, organoleptic tests, homogeneity tests, pH tests, spreadability tests and viscosity tests were carried out. Testing the effectiveness of wound healing using 5 groups consisting of 3 mice. Each group was giffen different treatment, namale K- was given an ointment base, K+ was given betadine ointment, F1 was given an ointment with a concetration of 2,5%, F2 was given an ointment with a concentration of 5% and F3 was given an ointment with a concentration of 7,5%. The results showed that the ointment met the standard organoleptic test requirements, test homogeneity, pH test, spreadability test and viscosity test. Based on the results of the incision test on mice, the most effective ointment preparation was a preparation with a concentration of 5%
UJI EFEK HIPOGLIKEMIK EKSTRAK BUAH MERAH (Pandanus conoideus L.) TERHADAP MENCIT (Mus musculus) Dika Rahayu; Lukman Hardia; Irwandi Irwandi
JURNAL ETNOFARMASI Vol. 1 No. 01 (2023): JURNAL ETNOFARMASI
Publisher : Universitas Pendidikan Muhammadiyah Sorong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36232/jurnalfarmasiunimuda.v1i01.1719

Abstract

Buah merah (P. conoideus L.) merupakan salah satu tanaman endemik yang secara tradisional dimanfaatkan oleh masyarakat Papua dengan cara mengambil sari buahnya dan telah digunakan oleh masyarakat untuk pengobatan berbagai penyakit degeneratif seperti diabetes mellitus. Penelitian ini bertujuan untuk mengetahui efek hipoglikemik ekstrak buah merah (Pandanus conoideus L.) terhadap mencit (Mus musculus). Penelitian ini menggunakan hewan uji mencit jantan sebanyak 25 ekor yang dibagi menjadi 5 kelompok perlakuan, tiap kelompok terdiri dari 5 ekor mencit jantan. Kelompok K+ diberi glibenklamid 0,433 mg/kg BB yang disuspensikan dengan Na-CMC 2% (kontrol positif) , kelompok K- diberi Na-CMC 2% (kontrol negatif), kelompok P1, P2, dan P3 diberi ekstrak buah merah masing-masing 0,175 g, 0,35 g, dan 0,7 g. Pemberian dilakukan dengan cara peroral dengan volume pemberian 1 mL/25 g BB, dan pengukuran kadar glukosa darah dilakukan setelah menit ke 30, 60, 90, dan 120 dengan menggunakan glukometer. Hasil penelitian menunjukan adanya aktivitas hipoglikemik pada mencit jantan yang diberikan glukosa secara oral. Konsentrasi dosis yang paling efektif dan memiliki efek sebanding dengan kontrol positif suspensi glibenklamid dalam menurunkan kadar glukosa darah mencit yaitu konsentrasi dosis 0,175 gram.
EVALUASI POLA PERESEPAN OBAT ANTI HIPERTENSI Di PUSKESMAS Aulia Mifthakul Jannah; Lukman Hardia; Angga Bayu Budiyanto
JURNAL ETNOFARMASI Vol. 1 No. 01 (2023): JURNAL ETNOFARMASI
Publisher : Universitas Pendidikan Muhammadiyah Sorong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36232/jurnalfarmasiunimuda.v1i01.1722

Abstract

Kriteria pemakaian obat secara rasional meliputi tepat diagnosa, tepat indikasi penyakit, tepat pemilihan obat, tepat pasien, tepat dosis, tepat cara pemakaian, tepat interval waktu pemberian, tepat lama pemberian, serta waspada terhadap efek samping. Evaluasi peresepan obat penting dilakukan untuk mengetahui dan memastikan bahwa pasien telah menerima pengobatan yang sesuai dengan kebutuhan klinisnya, dalam dosis dan jangka waktu yang sesuai, dan dengan biaya terendah. Ketidakrasionalan peresepan masih sering ditemukan terutama di Puskesmas yang merupakan pusat pelayanan kesehatan tingkat 1, dimana obat dan dosis yang diresepkan oleh tenaga medis kurang sesuai akibat ketersediaan obat yang terbatas, dan salah satunya adalah obat hipertensi. Sehingga perlu dilakukan evaluasi pola peresepan obat antihipertensi di Puskesmas Mariat Kabupaten Sorong periode Juli – September 2022. Penelitian ini bertujuan Untuk mengevaluasi pola peresepan obat anti-hipertensi di Puskesmas Mariat Kabupaten Sorong. Penelitian ini menggunakan rekam medis sebanyak 63 resep. Hasil penelitian Evaluasi Peresepan obat Antihipertensi Di Puskesmas Mariat Kabupaten Sorong Periode Juli-September 2022 bahwa tepat obat sebanyak 100% tepat pasien sebanyak 100% tepat dosis sebanyak 100%, tepat interval waktu pemberian sebanyak 88,46%. Obat Antihipertensi yang diberikan kepada pasien adalah terapi kombinasi golongan CCB+ACEI (amlodipin + captopril) dengan persentase yaitu 25% dan selanjutnya monoterapi amlodipin sebanyak 75%, dan captopril sebanyak 0%.
EFEKTIVITAS SALEP EKSTRAK ETANOL DAUN MANGROVE (Rhizophora mucronata) TERHADAP PENYEMBUHAN LUKA BAKAR PADA MENCIT JANTAN (Mus Muscullus) Indah Diah Ningrum; Ratih Arum Astuti; Lukman Hardia
JURNAL ETNOFARMASI Vol. 1 No. 01 (2023): JURNAL ETNOFARMASI
Publisher : Universitas Pendidikan Muhammadiyah Sorong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36232/jurnalfarmasiunimuda.v1i01.1723

Abstract

Mangrove (Rhizophora mucronata) mengandung flavonoid, saponin dan tanin. Senyawa yang terdapat dalam daun mangrove memiliki aktivitas antiinflamasi, antivirus, dan antimikroba. Berdasarkan senyawa yang dimiliki, mangrove (Rhizophora mucronata) bisa dimanfaatkan sebagai salep untuk luka bakar. Penelitian ini bertujuan untuk menguji sediaan salep ekstrak etanol daun mangrove terhadap penyembuhan luka bakar pada mencit. Proses ekstraksi daun mangrove (Rhizophora mucronata) menggunakan metode maserasi. Pada pengujian sediaan salep dilakukan uji organoleptik, uji homogenitas, uji pH, uji daya sebar dan uji viskositas. Pengujian efektivitas penyembuhan luka bakar menggunakan 5 kelompok yang terdiri dari 4 ekor mencit. Tiap kelompok diberi perlakuan berbeda yaitu K- diberi basis salep, K+ diberi betadin salep, F1 diberi salep konsentrasi 5%, F2 diberi salep konsentrasi 7,5% dan F3 diberi salep konsentrasi 10%. Hasil penelitian menunjukkan bahwa sediaan salep memenuhi syarat standar uji organoleptik, uji homogenitas, uji pH, uji daya sebar dan uji viskositas. Berdasarkan hasil uji luka bakar pada mencit sediaan salep yang paling efektif adalah sediaan dengan
Co-Authors A. M. Muslihin Achmad Noerkhaerin Putra Akrom, Akrom Angga Bayu Budianto Angga Bayu Budiyanto Angga Bayu Budiyanto Anisa, Meilinda Aponno, Alyssa Mileta Arif Radhika Mentari Arni, Veni Zafi Assem, Vincentia Santy Astuti, Ratih Arum Aulia Mifthakul Jannah Budianto, Angga Bayu Darmayanti Tumpu Diah Wulandari Dika Rahayu Dion Fahcrul Rozi Eka Savira Ni'ma Arfiani Erawati, Rika Eva Maya Sari Fabanyo, Syahrul H. fania, vikafania Fransiska, Gilda Indah Diah Ningrum Irwandi Irwandi Irwandi Irwandi Irwandi Irwandi Irwandi Jannah, Aulia Mifthakul Lanipi, Retna Parica Lanipi, Retna Paricca Levina Virginia M Natsir Djide M. Yogi Riyantama Isjoni Mansyur Arief Maulana, Fajar Meilinda Anisa Muh Ishar Difinubun Nanik Sulistyani Nazla Wati Sanaky Ningrum, Indah Diah Nuhidayah Sarifuddin Nuhidayah Sarifuddin Nur ‘Azah Nurwahyuni Paulus, Johan Kartino Pratama, Agus Sangka putri puspitawati, devyana Rahayu, Dika Rasi Fitri Yanti Tuasikal Retna Parica Lanipi Retna Parica Lanipi Retna Paricca Lanipi Rizky, Indah Amelia Rossardy, Marzella Dea Sanaky, Nazla Wati Sarifuddin, Nuhidayah Selfiana Iek Serlin Marsela Sintya Sari Dwi Kusumaningrum Siska Siska Siti Fatma Z.F. Sun, Suny Syahrul H. Fabanyo Titiek Suhardi Haripurnomo Kushadiwijaya Hidayati Tuasikal, Rasi Fitri Yanti Tunnazilah, Nurhikmah Tutuhatunewa, Priscillia Ryani ulandari, clarista windi Umpain, Agnes Nesa Utami, Hikmahtul Putri Vincentia Santy Assem Wa Ode Nurwahida Wael, Muh. Dahlan Wasaraka, Fadila Alfiah Watora, Wahyuni Wiwik Triyani Wiwik Wiwik, Wiwik Triyani Yanti, Inda Dwi Yapsenang, Amar Jansen Yuniatri, Nur Khusna Yusnita La Goa Zf, Siti Fatma