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All Journal International Journal of Public Health Science (IJPHS) Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Pharmaciana: Jurnal Kefarmasian Jurnal Penelitian Pendidikan IPA (JPPIPA) Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) Jurnal Kesehatan Manarang Biolearning Journal Jurnal Abdimasa PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Ners Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Science Midwifery Jurnal Promotif Preventif Mitra Mahajana: Jurnal Pengabdian Masyarakat Jurnal Kesehatan Tambusai JOURNAL LA MEDIHEALTICO International Journal of Health, Economics, and Social Sciences (IJHESS) Jurnal EduHealth Jurnal Sains dan Teknologi Sci-Tech Journal Jurnal Sains dan Kesehatan Jurnal Ilmiah Ilmu Terapan Universitas Jambi Journal of Pharmaceutical and Sciences. Jurnal Etnofarmasi Jurnal Mahasiswa Ilmu Kesehatan Journal of Public Health and Pharmacy Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Ilmu Kesehatan Jurnal Etnofarmasi
Lukman Hardia
Program Studi Farmasi, Fakultas Farmasi, Universitas Pendidikan Muhammadiyah Sorong
Aerospace Engineering Agriculture, Biological Sciences & Forestry Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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Studi Fitokimia Senyawa Aktif Ekstrak Batang Nelambo suon (Rubiaceae) Marzella Dea Rossardy; A.M. Muslihin; Wahyuni Watora; Angga Bayu Budiyanto; Lukman Hardia; Irwandi Irwandi; Alyssa Mileta Aponno; Hikmahtul Putri Utami
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1333

Abstract

Background: Papua has high biodiversity with significant potential as a source of traditional medicinal plants, including Nelambo suon (Rubiaceae), which has been empirically used by local communities. However, scientific information regarding the active compounds in its stem bark remains limited. Objective: This study aimed to identify the secondary metabolite groups present in the ethanol extract of Nelambo suon stem bark through phytochemical screening. Methods: The research was conducted experimentally using the maceration method with 80% ethanol as the solvent. The stem bark simplicia was extracted and qualitatively screened for alkaloids, flavonoids, tannins, and saponins using specific reagents. Results: The results showed that the ethanol extract of Nelambo suon stem bark contained alkaloids, flavonoids, tannins, and saponins, indicated by characteristic color changes, precipitate formation, and foam production. Conclusion: These findings suggest that Nelambo suon stem bark is a potential source of bioactive compounds and may be further developed as a herbal medicinal material based on local wisdom.
Nutritional profile and immunomodulatory potential of a polyherbal honey formulation for stunted children Akrom Akrom; Titiek Hidayati; Arif Budi Setianto; Laela Hayu Nurani; Ikhwan Dahlan Rais; Nurkhasanah Nurkhasanah; Lukman Hardia; Prasasti Bintarum; Muslih Anwar
International Journal of Public Health Science (IJPHS) Vol 15, No 3: September 2026
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v15i3.23026

Abstract

Stunting remains a major public health challenge in Indonesia and has been linked to immune dysregulation, including increased pro-inflammatory TNF-α and reduced anti-inflammatory IL-4 activity. Nutrient-dense polyherbal supplementation may provide a complementary strategy to support nutritional status and immune function. This experimental study investigated the nutritional composition and immunomodulatory activity of polyherbal honey (PHH) formulated with curcuma xanthorrhiza, black cumin seeds, and honey. Vitamins, minerals, and bioactive constituents were characterized using laboratory assays. The immunomodulatory effects of PHH were subsequently evaluated in HTB-183 cells by measuring IL-4 and TNF-α expression after exposure to different formulation concentrations. The analysis confirmed the presence of vitamins A, C, and E; calcium and potassium; and several bioactive compounds in the PHH formulation. PHH exposure increased IL-4 expression and reduced TNF-α expression relative to untreated cells, although the magnitude of these responses varied across concentrations. These findings demonstrate that PHH contains nutritional and phytochemical constituents with potential immunomodulatory activity. Further preclinical and clinical investigations are required to determine its efficacy and safety as complementary nutritional support for children with stunting.
Hubungan Faktor Risiko dengan Penggunaan Obat pada Pasien Sindrom Ovarium Polikistik di Klinik Kencana, Kota Sorong Adriyani E. G. Sitanggang; Lukman Hardia; Irwandi Irwandi
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 3 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i3.1794

Abstract

Polycystic ovary syndrome (PCOS) requires individualized pharmacotherapy because reproductive and metabolic manifestations vary among patients. This study evaluated the associations of age, documented menstrual complaints, and pregnancy-related presentations with medication-count category among patients with PCOS at Kencana Clinic, Sorong City. A retrospective cross-sectional analysis was conducted on 118 eligible records selected by computer-generated simple random sampling from 412 records dated January 2022-December 2023. Associations were analyzed using the chi-square test and expressed as odds ratios (ORs) with 95% confidence intervals (CIs). Patients aged >25 years were more likely to receive >2 medications than those aged ≤25 years (40/73 vs 16/45; OR = 2.197; 95% CI = 1.022-4.721; p = 0.042). Menstrual complaints and pregnancy-related presentations were not significantly associated with medication-count category (p = 0.297 for each comparison). Older age was associated with greater medication-count complexity, but did not establish causality. Treatment planning should integrate age with metabolic status, comorbidities, and reproductive goals.
Co-Authors A. M. Muslihin Achmad Noerkhaerin Putra Adriyani E. G. Sitanggang Agus sangka pratama Akrom Akrom Akrom, Akrom Alyssa Mileta Aponno Angga Bayu Budianto Angga Bayu Budiyanto Angga Bayu Budiyanto Angga Bayu Budiyanto Angga Bayu Budiyanto Angga Bayu Budiyanto Anisa, Meilinda Arif Budi Setianto Arif Radhika Mentari Arni, Veni Zafi Assem, Vincentia Santy Astuti, Ratih Arum Aulia Mifthakul Jannah Azzahra Vivin Mahdiya Afandy Budianto, Angga Bayu Carmel Josuhua Paulus Darmayanti Tumpu Diah Wulandari Dian Nur Khofifah Dika Rahayu Dion Fahcrul Rozi Eka Savira Ni'ma Arfiani Erawati, Rika Ernifan Ernifan Eva Maya Sari Fabanyo, Syahrul H. Fajar Maulana fania, vikafania Gilda Fransiska Hikmahtul Putri Utami Ica Damayanti Ikhwan Dahlan Rais Inda Dwi Yanti Indah Amelia Rizky Indah Diah Ningrum Innal Saitis Innal Saitis Irene Eunike Tanod Irwandi Irwandi Irwandi Irwandi Irwandi Irwandi Irwandi Irwandi Irwandi Jannah, Aulia Mifthakul Justitia Cahyani Fadli Laela Hayu Nurani Lanipi, Retna Parica Lanipi, Retna Paricca Levina Virginia M Natsir Djide M. Yogi Riyantama Isjoni Mansyur Arief Marzella Dea Rossardy Meilinda Anisa Mika Tri Kumala Swandari Muh Ishar Difinubun Muh. Dahlan Wael Muslih Anwar Nanik Sulistyani Nanik Sulistyani Nazila Galela Nazla Wati Sanaky Ningrum, Indah Diah Nuhidayah Sarifuddin Nuhidayah Sarifuddin Nur ‘Azah Nurkhasanah Nurkhasanah Nurul Maghfirah1 Nurwahyuni Paulus, Johan Kartino Prasasti Bintarum Pratama, Agus Sangka putri puspitawati, devyana Rahayu, Dika Rasi Fitri Yanti Tuasikal Retna Parica Lanipi Retna Parica Lanipi Retna Paricca Lanipi Risanyel Elsan Tuturop Rizqi Fadil Nadila SALIM, MUH.AGUS Sanaky, Nazla Wati Sarifuddin, Nuhidayah Selfiana Iek Serlin Marsela Sintya Sari Dwi Kusumaningrum Siska Siska Siti Fatma Z.F. Siti Rahmadani Sitti Hadija Samual Sun, Suny Syahrul H. Fabanyo Titiek Hidayati Titiek Suhardi Haripurnomo Kushadiwijaya Hidayati Tuasikal, Rasi Fitri Yanti Tunnazilah, Nurhikmah Tutuhatunewa, Priscillia Ryani ulandari, clarista windi Umpain, Agnes Nesa Vincentia Santy Assem Wa Ode Nurwahida Wahyuni Watora Wasaraka, Fadila Alfiah Wiwik Triyani Wiwik Wiwik, Wiwik Triyani Wiwit Ayu Fitrianti Yapsenang, Amar Jansen Yuniatri, Nur Khusna Yusnita La Goa Zf, Siti Fatma