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Potential Pharmaceutical Biotechnology Products in the Form of Formulations and Preparations of Telang Flower Kombucha Dish Soap (Clitoria ternatea L) as an Antibacterial from Beef (Bos taurus) Isolate Rezaldi, Firman; Nurvadilah, Eva; Junaedi, Candra; Somantri, Ucu Wandi; Fadillah, M. Fariz; Maritha, Vevi; Yenny, Ratna Fitry; Setyaji, Diyan Yunanto
Journal of Health and Nutrition Research Vol. 3 No. 1 (2024)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v3i1.237

Abstract

This research aims to see the potential of each formulation and preparation of dishwashing soap with the active ingredient telang flower kombucha in inhibiting the growth of pathogenic bacteria isolated from beef. This research is a laboratory experiment, namely by making a dishwashing soap base without the active substance of telang flower kombucha. Make a dishwashing soap base that adds the active substance of butterfly pea flower kombucha at concentrations of 20%, 30% and 40%. Biochemical identification results have shown that beef samples contain gram-positive bacteria in the form of Staphylococcus aureus and Listeria monocytogenes, as well as gram-negative bacteria in the form of Salmonella thyposa and Escherichia coli. The results of this research have also proven that pharmaceutical biotechnology products in the form of formulations and dishwashing soap preparations with the active ingredient telang flower kombucha have a positive correlation in inhibiting the growth of the four test bacteria. Based on the one-way ANOVA statistical test at each P value <0.05, it proves that telang flower kombucha dish soap at a concentration of 40% according to post hoc analysis is not significantly different from concentrations of 20% and 30% as a pharmaceutical and antibacterial biotechnology product. isolated from beef. The conclusion of this research is that the formulation and preparation of dishwashing soap at a concentration of 40% proved to be the most effective as a pharmaceutical biotechnology product in inhibiting the growth of the four test bacteria.
Antioxidant Activity in Pharmaceutical Biotechnology Products in The Form of Formulations and Preparations of Telang Flower Kombucha Hand Soap (Clitoria ternatea L) Maigoda, Tonny Cortis; Hariadi, Hari; Triyono, Agus; Rezaldi, Firman; Sugiono, Sugiono; Saifullah, Ipul; Munir, Misbakhul; Kurniawan, Maskun; Rohmatulloh, Rizal; Yenny, Ratna Fitry; Pamungkas, Barolym Tri; Amin, Suseno; Judiono, Judiono
Jurnal Biologi Tropis Vol. 24 No. 2 (2024): April - Juni
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i2.7195

Abstract

Free radicals need to be handled and even prevented so that they are not exposed to the skin, especially the hands. One solution to preventing the exposure of free radicals to the skin of the hands is to wash your hands with herbal soap which is made from the active ingredient of telang flower kombucha. Telang flower kombucha was designed as an active ingredient in the formulation and hand washing soap preparation in this research has been proven as a pharmaceutical biotechnology product in warding off free radicals. This research was designed by making a formulation and preparation of telang flower kombucha hand washing soap at concentrations of 20%, 30% and 40% then measuring it using UV-Vis spectrophotometry. Based on statistical analysis, especially post hoc analysis of pharmaceutical biotechnology products in the form of formulations and preparations of telang flower kombucha hand washing soap at a concentration of 40%, it is significantly different from 20% and 30% as a source of antioxidants.
The Effect of Concentrations Bioherbicide Kirinyuh Leaf Extract to Control The Growth of Teki Weeds Nudin, Fatwa; Nurmayulis, Nurmayulis; Yenny, Ratna Fitry; Putri, Widia Eka
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.8167

Abstract

The research was aimed to know the effect of different concentrations bioherbicide of kirinyuh leaf extract to control the growth of teki weeds. This research was conducted from Juny until August 2024 in Sindang Resmi, Purwaraja village, Menes district, Pandeglang city, Banten and Biotechnology Laboratory, Faculty of Agriculture, Sultan Ageng Tirtayasa University. The method used Randomized Completely Block Design with one factor. The factor with five replications to obtain 25 experimental units, namely: 25%, 50%, 60%, 75% and 90% . The results showed that kirinyuh leaf extract 90% has a significant effect for plant height at 5 days after planting (DAP) (4.40 cm), 10 DAP (13.40 cm), 20 DAP (21.60 cm), 25 DAP (26.60 cm) and 30 DAP (27.80 cm). Plant dry weight (6.00 g) and crown dry weight (3.20 g). The treatment of different consentrations of kirinyuh leaf extract showed significant differences on the parameters.
Antibakteri Keracunan Bahan Pangan Pada Formulasi Sediaan Sabun Mandi Kombucha Bunga Telang Sebagai Produk Bioteknologi Farmasi Dari 3 Lokasi Budidaya Fadhillah, Maya; Rezaldi, Firman; Yenny, Ratna Fitry; Maritha, Vevi; Ayuwardani, Novi; Suminar, Erni
Jurnal Ilmiah Biosaintropis (Bioscience-Tropic) Vol 10 No 1 (2024): Agustus 2024
Publisher : Fakultas Matematika & Ilmu Pengetahuan Alam - Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/ejbst.v10i1.586

Abstract

 Produk bioteknologi farmasi dalam bentuk formulasi dan sediaan sabun mandi cair kombucha bunga telang dapat dimanfaatkan sebagai salah satu sediaan farmasi atau kosmetik yang bersifat antibakteri penyebab keracunan bahan pangan dan sebelumnya telah teruji pada formulasi dan sediaan sabun cuci tangan berbahan aktif kombucha bunga telang, sehingga pada penelitian ini penulis tertarik untuk menggunakan 3 lokasi budidaya tanaman bunga telang. Penelitian ini bertujuan untuk membuat formulasi dan sediaan sabun mandi cair berbahan aktif kombucha bunga telang yang diperoleh dari tiga lokasi budidaya yaitu kampung pekuncen kota cilegon, kampung cinangka anyer kabupaten serang, dan desa banjarwangi kabupaten pandeglang banten. Penelitian ini bersifat eksperimental laboratorium yaitu dengan cara membuat basis sabun mandi cair tanpa zat aktif, membuat basis sabun mandi cair dengan bahan aktif kombucha bunga telang pada konsentrasi 20%, 30%, dan 40% yang diperoleh dari 3 lokasi budidaya, dan menyediakan sabun mandi pasaran sebagai kontrol positif. Metode dalam pengujian sediaan farmasi (kosmetik/sabun mandi cair) melalui difusi cakram. Data mengenai rata-rata diameter zona hambat dianalisis melalui ANOVA satu jalur jika terdapat perbedaan secara signifikan dilanjut melalui analisis pos hoc Hasil penelitian ini telah terbukti bahwa masing-masing bunga telang yang dibudidayakan dari 3 lokasi dan juga dibuat sebagai formulasi dan sediaan sabun mandi cair kombucha berkolerasi secara positif dalam menghambat keemepat pertumbuhan bakteri uji. Berdasarkan analisis ANOVA satu jalur dengan masing-masing nilai P<0,05, maka dapat dilakukan uji lanjut berupa analisis pos hoc dimana formulasi dan sediaan sabun mandi cair berbahan aktif kombucha bunga telang dari 3 lokasi budidaya pada konsentrasi 40% berbeda nyata dengan konsentrasi 20% dan 30% sebagai antibakteri penyebab keracunan bahan pangan baik yang dihasilkan dari Lokasi budidaya kampung pekucen, kota cilegon banten, kampung cinangka kabupaten serang, banten, dan desa banjarwangi, kabupaten pandeglang, banten.
AKTIVITAS ANTIOKSIDAN PADA SEDIAAN KOMBUCHA BUNGA TELANG YANG DIRACIK DARI FORMULASI GULA AREN DAN MADU SR12 SEBAGAI PRODUK BIOTEKNOLOGI PANGAN DAN FARMASI Rezaldi, Firman; Utami, Arti Wahyu; Resti Wijayanti, Fitria Eka; Purbanova, Reni; Wati, Dyah Rohma; Suminar, Erny; Kusumiyati, Kusumiyati; Mu’jijah, Mu’jijah; Faizah, Nai’matul Retno; Cahyono, Andri Tri; Setyaji, Diyan Yunanto; Fadillah, M Fariz; Yenny, Ratna Fitry
AGRIBIOS Vol 22 No 2 (2024): November
Publisher : Program Studi Agribisnis Fakultas Pertanian

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36841/agribios.v22i2.5209

Abstract

The food and pharmaceutical fields are two elements needed in everyday life to improve human health and well-being. This is because functional foods, medicines, and natural cosmetics have become an increasingly current trend to be applied both based on food biotechnology and pharmaceutical biotechnology. One of the food and pharmaceutical biotechnology products that can be effective as a source of antioxidants is the butterfly pea flower kombucha preparation. Butterfly pea flower kombucha preparations that are effective as a source of antioxidants certainly have a substrate formula that varies based on the results of their concoctions. The results of previous studies have proven that butterfly pea flower kombucha with a concentration of palm sugar and SR12 honey has activity as a source of antibacterial. Research to see the antioxidant activity that is formulated based on various formulations of palm sugar and SR12 honey substrates. The stages of this research include making butterfly pea flower kombucha with various concentrations of palm sugar and SR12 honey substrates and testing its antioxidant activity on each preparation formulated from the palm sugar and SR12 honey substrate formulation (20%, 30%, and 40%). One-way analysis of variance was applied, followed by post-hoc analysis. Based on the post-hoc analysis, the study showed that butterfly pea flower kombucha at a concentration of 40%, as well as the formula of palm sugar and SR12 honey, showed significant differences from the concentrations of 20% and 30% after testing one-way analysis of variance, with each P value <0.05. The conclusion is that the preparation of butterfly pea flower kombucha based on the use of palm sugar and SR12 honey substrates is efficacious as a source of antioxidants so that in the long term it can be used as a functional food ingredient or pharmaceutical.
FORMULASI SEDIAAN SPRAY ALAMI PADA KOMBUCHA BUNGA TELANG SEBAGAI PRODUK BIOTEKNOLOGI FARMASI DAN ANTIFUNGI PADA TANAMAN KOMODITAS HORTIKULTURA JENIS KENTANG (Solanum tuberosum L) Rezaldi, Firman; Maritha, Vevi; Yenny, Ratna Fitry; Saifullah, Ipul; Sugiono, Sugiono; Rohmatulloh, Rizal; Munir, Misbakhur; Setiawan, Usman; Mubarok, Syariful; Kusumiyati, Kusumiyati
AGRIBIOS Vol 22 No 1 (2024): JUNI
Publisher : Program Studi Agribisnis Fakultas Pertanian

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36841/agribios.v22i1.4600

Abstract

Tanaman kentang memiliki manfaat sebagai sumber karbohidrat, sehingga dapat dimanfaatkan sebagai menu pengganti nasi. Gagalnya panen pada tanaman kentang disebabkan oleh faktor faktor biotik yang sangat potensial dalam menyerang tanaman kentang sehingga para petani sulit dalam memenuhi permintaan pasar dalam jangka waktu terkendali maupun tidak terkendali. Fungi patogen penyebab busuk pada tanaman kentang yaitu spesies Phytophthora infestans. Fungi patogen penyebab bercak cokelat pada tanaman kentang berupa Ralstonia solanacearum merupakan spesies fungi patogen penyebab layu pada daun tanaman kentang, sehingga dibutuhkan antibiotik secara natural dari kombucha bunga telang yang cukup ramah lingkungan dengan pertimbangan adanya penggunaan pestisida secara kimiawi cukup potensial dalam merusak lingkungan budidaya tanaman. Penelitian ini bersifat eksperimental laboratorium yaitu dengan cara membuat formulasi dan sediaan spray kombucha bunga telang pada konsentrasi 20%, 30%, dan 40%, menyediakan aquadest steril yang dirancang sebagai kontrol negatif, menyediakan antibiotik pasaran sebagai kontrol positif. Tahapan tahapan penelitian ini meliputi persiapan bunga telang, kultur awal kombucha, fermentasi kombucha bunga telang, menguji daya hambat pertumbuhan fungi patogen dari masing-masing formulasi dan sediaan spray kombucha bunga telang, dan analisis data. Hasil penelitian ini telah terbukti bahwa seluruh formulasi dan sediaan kombucha bunga telang dapat dimanfaatkan sebagai antifungi bagi tanaman kentang yang cukup potensial dalam diserang fungi patogen, sehingga perlu diberikan edukasi bagi petani dalam pemanfaatan kombucha bunga telang untuk diperankan sebagai minuman probiotik peningkat sistem imun maupun sediaan spray natural yang ramah lingkungan.
PENGARUH BERBAGAI JENIS PUPUK KOTORAN HEWAN DAN VITAMIN B KOMPLEKS TERHADAP PERTUMBUHAN TANAMAN DURIAN (Durio zibethinus Murr.) Dewi, Resti Susilawati; Susiyanti, Susiyanti; Rohmawati, Imas; Fatmawaty, Andi Apriany; Yenny, Ratna Fitry
Agros Journal of Agriculture Science Vol 25, No 4 (2023): edisi Oktober
Publisher : Fakultas Pertanian, Universitas Janabadra

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37159/jpa.v25i4.3520

Abstract

This study aims to determine the type of animal manure fertilizer and the best type of vitamin B complex on the growth of durian plants (Durio zibethinus Murr.). The research used was a factorial Randomized  Block Design (RBD) with two factors and three replications. The first factor with 3 levels: P1 : goat manure fertilizer, P2 : cow manure fertilizer and P3: chicken manure fertilizer. The second factor with 3 levels: V1: B1 thiamin, V2: B3 nicotinic acid and V3: B6 pyridoxine. The results showed that the application of cow dung fertilizer had a significant effect on the parameters of shoot number increase and leaf number increase. The type of vitamin B complex B1 thiamin significantly influenced the parametersof shoot number increase and leaf number increase. There is an interaction between the treatment of various types of animal manure fertilizer and types of vitamin B complex on the parameters of shoot number increase and leaf number increase. Durian cultivation can be done using cow dung fertilizer and vitamin B complex at appropriate doses. Keywords: animal manure fertilizer, durian, vitamin B complex INTISARI Penelitian ini bertujuan untuk mengetahui jenis pupuk kandang dan jenis vitamin B kompleks yang terbaik terhadap pertumbuhan tanaman durian (Durio zibethinus Murr.). Penelitian yang digunakan adalah Rancangan Acak Kelompok (RAK) faktorial dengan dua faktor dan tiga kali ulangan. Faktor pertama dengan 3 taraf: P1: pupuk kotoran kambing, P2: pupuk kotoran sapi dan P3: pupuk kotoran ayam Faktor kedua dengan 3 taraf: V1: B1 thiamin, V2: B3 asam nikotinat dan V3: B6 piridoksin. Hasil penelitian menunjukkan bahwa pemberian pupuk kotoran sapi berpengaruh nyata terhadap parameter pertambahan jumlah tunas dan pertambahan jumlah daun. Jenis vitamin B kompleks B1 thiamin berpengaruh nyata terhadap parameter pertambahan jumlah tunas dan pertambahan jumlah daun. Terdapat interaksi antara perlakuan macam pupuk kotoran sapi dan jenis vitamin B kompleks terhadap parameter pertambahan jumlah tunas dan pertambahan jumlah daun. Budidaya tanaman durian dapat dilakukan menggunakan pupuk kotoran sapi dan vitamin B kompleks dengan dosis yang sesuai. Kata kunci: pupuk kotoran hewan, durian, vitamin B kompleks