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All Journal Pharmaciana: Jurnal Kefarmasian Jurnal Riset Kimia Medical Laboratory Technology Journal Jurnal Penelitian Farmasi Indonesia Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) JSFK (Jurnal Sains Farmasi & Klinis) JURNAL PHOTON JFL : Jurnal Farmasi Lampung Jurnal Ilmu Kefarmasian Indonesia Jurnal Midpro Jurnal Ilmiah Farmako Bahari Jurnal Farmasi Sains dan Praktis Jurnal Bakti Nusantara Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Rahma Dona
Sekolah Tinggi Ilmu Farmasi Riau
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Physics Public Health Other

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ISOLASI DAN UJI AKTIVITAS ANTIBAKTERI SENYAWA METABOLIT SEKUNDER DARI EKSTRAK METANOL DAUN MARPUYAN (Rhodamnia cinerea Jack.) Musyirna Rahmah Nst; Dwi Andreyas; Rahma Dona; Emrizal; Emma Susanti; Ihsan Ikhtiarudin; Rahayu Utami
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 9 No. 2 (2023): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v9i2.671

Abstract

A study on isolation and antibacterial activity of secondary metabolites from the methanol extract of Marpuyan (Rhodamnia cinerea Jack.) Leaves on Escherichia coli has been carried out. Isolation was carried out by column chromatography methods. Whereas the antibacterial activity test was carried out using agar diffusion method. The results of the isolation produced 17.9 mg of RC-F13 isolate compound in the form of light yellow crystals, with a melting point of 170-172oC and soluble in methanol. The results of identification of RC- F13 isolate compounds through testing with AlCl3 reagents, positive including the flavonoid group, were strengthened by the results of the UV spectrum and FT-IR spectrum. Based on the results of the UV spectrum, it was seen that the RC- F13 isolate compound showed λ max 353.60, 257.00 and 209.20 nm. The FT-IR spectrum shows the presence of several functional groups such as OH, C aliphatic C-H, C = O carbonyl, C = C aromatic and C-O. testing the antibacterial activity of methanol extract with a concentration of 20%; 10%; 1%; 0.1% and 0.01%, fraction 13 at 1% concentration; 0.1% and 0.01% and RC- F13 isolate compound concentration of 0.1%, against Escherichia coli bacteria did not show any antibacterial activity which was marked by the absence of clear areas around the disc.
The Isolatıon, Characterızatıon, and Antıfungal Assay of Lactıc Acıd Bacterıa Isolated from Green Glutınous Rıce Tape Agaınst Aspergillus flavus Nasution, Musyirna Rahmah; Aulya, Nurliza; Dona, Rahma; Ningsih, Yozi Fiedya
Medical Laboratory Technology Journal Vol. 11 No. 1 (2025): June
Publisher : Poltekkes Kemenkes Banjarmasin Jurusan Analis Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/mltj.v11i1.645

Abstract

Green glutinous rice tape is a fermented food made from glutinous rice, katuk leaves (Sauropus androgynus), and yeast, originating from Tembilahan, Riau Province. This product can serve as a source of lactic acid bacteria (LAB) capable of producing antimicrobial compounds to inhibit pathogenic microorganisms, including Aspergillus flavus, a well-known spoilage fungus in food products. However, to date, no reports have explored the ability of LAB from green glutinous rice tape to inhibit the growth of Aspergillus flavus. This study aimed to isolate LAB from green glutinous rice tape, conduct macroscopic, microscopic, and biochemical characterizations, and evaluate the antifungal activity of the LAB isolates against Aspergillus flavus using the good diffusion method. The isolation process yielded four LAB isolates from Tembilahan green tape (TKHT-2, TKHT-3, TKHT-5, and TKHT-7), which were identified as members of the genus Lactobacillus sp., with antifungal activities of 25.50 ± 5.78 mm, 24.33 ± 0.62 mm, 22.16 ± 6.56 mm, and 18.66 ± 4.28 mm, respectively. The corresponding cell-free supernatants (CFS) from these isolates (TKHT-S2, TKHT-S3, TKHT-S5, and TKHT-S7) also demonstrated antifungal activity with inhibition zones of 19.83 ± 3.47 mm, 19.83 ± 4.24 mm, and 14.50 ± 3.26 mm, respectively. LAB cells and their cell-free supernatants partially inhibited Aspergillus flavus, indicating a fungistatic effect. These findings suggest the potential application of LAB from green glutinous rice tape as a natural preservative or antifungal agent in food products.
Penyuluhan Pentingnya Pengetahuan Menjaga Kesehatan Ginjal Masyarakat di Stadion Utama Riau Novita, Gressy; utari, Mayang; Octaviani, Melzi; Dona, Rahma; Anggraeni, Silvana; Kasnaidi, Ahmad Faisal; Jonang, Aqila Rifdah; Khairiah, Kinanti Bahy; Sasnita, Nadya Ayu; Novita, Nova; Sari, Novita; Rizki Annisa A; Septiani Nindia Putri; Suci Anggela Soraya
Jurnal Bakti Nusantara Vol. 2 No. 3 (2025): Jurnal Bakti Nusantara
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/jbn.v2i3.87

Abstract

Penyakit ginjal merupakan salah satu masalah kesehatan global yang semakin meningkat prevalensinya. Penyakit ginjal kronik menempati urutan ke-12 sebagai penyebab kematian tertinggi di dunia, dengan tren peningkatan setiap tahunnya. Di Indonesia, prevalensi penyakit ginjal kronis mencapai 0,38%, namun diperkirakan angka sebenarnya lebih tinggi mengingat banyak kasus tidak terdeteksi pada tahap awal. Penyebab dari meningkatnya angka penderita penyakit ginjal di Indonesia adalah karena pola hidup yang tidak sehat, kurangnya pengetahuan dan terbatasnya akses informasi tentang cara mencegah penyakit ginjal. Pengabdian masyarakat ini bertujuan untuk mengedukasi masyarakat tentang kesehatan ginjal dan cara pencegahannya. Metode yang digunakan adalah penyuluhan secara langsung menggunakan media leaflet dan diskusi. Materi edukasi adalah mengenai kesehatan ginjal, mulai dari cara menjaga kesehatan ginjal, mengetahui gejala dan faktor resiko penyebab penyakit ginjal tersebut. Evaluasi kegiatan dilakukan dengan memberikan tes awal dan tes akhir. Berdasarkan hasil pretes dan postes dapat disimpulkan bahwa terdapat pengaruh pemberian penyuluhan secara langsung menggunakan media leaflet terhadap pengetahuan masyarakat di Stadion Utama Riau. Hal ini dapat dilihat pada uji Wilcoxon pada skor pretest dan posttest yaitu dengan nilai p value 0,000 (p<0,05). Melalui pengabdian ini, diharapkan masyarakat dapat lebih memahami pentingnya menjaga kesehatan ginjal serta mengubah pola hidup mereka menjadi lebih sehat. Pada akhirnya, seiring dengan meningkatnya pengetahuan masyarakat, maka diharapkan terjadi penurunan angka penderita penyakit ginjal di Indonesia.
Co-Authors Abdi Wira Septama Abdi Wira Septama Adel Zamri Adel Zamri Adel Zamri Adel Zamri agistia, nesa Ainun Alfatma Anggraeni, Silvana Armon Fernando Armon Fernando Aulya, Nurliza BENNI ISKANDAR Dwi Andreyas Emrizal Enda Mora Fikri Maulana Fikri Maulana, Fikri Fina Aryani, Fina Furi, Mustika Gressy Novita Haiyul Fadhli Hendra, Rudi Husnawati Ihsan Ikhtiarudin Jasril Jasril Jonang, Aqila Rifdah Kasnaidi, Ahmad Faisal Khairiah, Kinanti Bahy Laela Hayu Nurani Melzi Octaviani Milianty, Jesy Musyirna Rahmah Nst Muthui’ah Muthui’ah Nahdiah Nahdiah Nahdiah Nahdiah, Nahdiah Nanik Sulistyani Neni Frimayanti Ningrum, Tilar Eka Widia Ningsih, Yozi Fiedya Nofriyanti Nova Novita Nova Tantri Silalahi Novita Sari Nurul Susianti Rahayu Utami Rahayu Utami Rizki Annisa A Ronapadua Musyirna Rahmah Nasution Sahara dan Emma Susanti Rosnita Dewi Rahmawati Sasnita, Nadya Ayu Selvia Selvia Septi Muharni Septiani Nindia Putri Silalahi, Nova Tantri Sinata, Novia Suci Anggela Soraya Syahbandi, Ilham Tyasakti Viryana utari, Mayang Vincent Tristan Winda Tria Safitri Wira Noviana, Wira Noviana YANTO YANTO