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All Journal Pharmaciana: Jurnal Kefarmasian IDJP (Indonesian Journal of Pharmaceutics) JSFK (Jurnal Sains Farmasi & Klinis) Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang Jurnal Pengabdian UNDIKMA Jurnal Ilmiah Farmasi Simplisia Jurnal Farmasi Galenika Sadewa: Jurnal Pengabdian Masyarakat
Mikhania Christiningtyas Eryani
Bagian Farmasetika, Fakultas Farmasi Universitas Jember; Program Magister Farmasi, Fakultas Farmasi Universitas Jember
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Crystal Engineering of Ibuprofen and Caffeine by Cocrystal Formation Using Solvent Evaporation and Slurry Methods Mikhania Christiningtyas Eryani; Yudi Wicaksono; Budipratiwi Wisudyaningsih; Kuni Barikah; Hery Febrianto
JSFK (Jurnal Sains Farmasi & Klinis) Vol 13 No 1 (2026): J Sains Farm Klin 13(1), April 2026
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.13.1.15-20.2026

Abstract

Ibuprofen is a pharmaceutical active compound used to treat mild to moderate pain and fever. However, ibuprofen has low solubility in water. One method to increase solubility is cocrystal formation. The ibuprofen cocrystal was prepared in this study using caffeine as a coformer at a 1:1 molar ratio via solvent evaporation and slurry methods. The results of the XRD and thermal analysis of the sample indicate that a new solid phase is formed in the specific sa mple, which is different from both of its constituent components. Morphologically, the resulting cocrystals show a change in shape from their constituent compounds as well as a change in size. The solubility test results show that cocrystal formation is able to increase the solubility of ibuprofen. The conclusion of this study is that ibuprofen cocrystals can be formed with the coformer caffeine at a molar ratio of 1:1 using the slurry method and solvent evaporation.
BIJAK MENGGUNAKAN KOSMETIK DAN SUPLEMEN KESEHATAN rashati Dewi; Asa Falahi; anies Rohman Dwijayanti; Mikhania Christiningtyas Eryani
Jurnal SADEWA Vol 4 No 01 (2026): Sadewa: Jurnal Pengabdian Masyarakat
Publisher : LPPM Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/sadewa.v4i01.1096

Abstract

Teenagers are the next generation and the determining factor of the nation's future. The use of supplements and cosmetics is an important matter for teenagers to fulfill. The consumption of supplements by teenagers is a form of daily nutritional fulfillment activity. The use of cosmetics also attracts the attention of teenagers. The aim of this community service is to provide education on SMK Farmasi dr. Soebandi student to be wise in using cosmetics and health supplements. The method in this activity using explanation method and quantitative questionnaire data collection. This activity has a positive impact on increasing student knowledge also awareness of the importance of choosing and using cosmetics and supplements safely. That can be seen the increase pre-post test score from 63 to 80. Although the increase knowledge statistically is not significant, but this activity enhances participants understanding and encourages more rational consumer behavior.
Co-Authors Adelia Firandi Adi Prayitno Amaliyah Nurul Hidayah anies Rohman Dwijayanti Ardian Baitariza, Ardian Asa Falahi Ayuning Trias, Diah Budipratiwi Wisudyaningsih Denok Risky Ayu Paramita Dewi Riskha Nurmalasari Erika Herawati, Irma Hery Febrianto Ika Norcahyanti Januarti, Melinda Judy Handojo, Kukuh Kuni Barikah Nur Patihul Patihul Husni rashati Dewi Rashati, Dewi Safitri, Manzil Tryani Sutisna Putri, Sussy Yudi Wicaksono